WILLIAM contact PERRY

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc Quantifying over-activity in bipolar and schizophrenia patients in a human open field paradigm
    William Perry
    Department of Psychiatry, University of California, San Diego, La Jolla, CA 92093 8218, USA
    Psychiatry Res 178:84-91. 2010
  2. pmc Beyond the numbers: expanding the boundaries of neuropsychology
    William Perry
    Department of Psychiatry, University of California, San Diego, CA 92093 8620, USA
    Arch Clin Neuropsychol 24:21-9. 2009
  3. ncbi request reprint Sensorimotor gating deficits in adults with autism
    William Perry
    Department of Psychiatry, University of California, San Diego, California, USA
    Biol Psychiatry 61:482-6. 2007
  4. ncbi request reprint Neuropsychological test performance in patients co-infected with hepatitis C virus and HIV
    William Perry
    Hepatology Neurobehavioral Research Program, University of California, San Diego, CA 92103 8218, USA
    AIDS 19:S79-84. 2005
  5. ncbi request reprint A retrospective review of the neuropsychological test performance of physicians referred for medical infractions
    William Perry
    Department of Psychiatry, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093 8218, USA
    Arch Clin Neuropsychol 20:161-70. 2005
  6. ncbi request reprint Prepulse inhibition in patients with non-psychotic major depressive disorder
    William Perry
    Department of Psychiatry, University of California San Diego, 200 West Arbor Drive, Mailcode 8218, San Diego, CA 92103 8218, USA
    J Affect Disord 81:179-84. 2004
  7. ncbi request reprint Let's call the whole thing off: a response to Dawes (2001)
    William Perry
    Department of Psychiatry, University of California, San Diego, 9500 Gilman Drive, La Jolla, California 92093 8218, USA
    Psychol Assess 15:582-5. 2003
  8. ncbi request reprint The use of the Ego Impairment Index across the schizophrenia spectrum
    William Perry
    Department of Psychiatry, University of California, San Diego, La Jolla, CA 92093 8620, USA
    J Pers Assess 80:50-7. 2003
  9. ncbi request reprint Information processing deficits in acutely psychotic schizophrenia patients medicated and unmedicated at the time of admission
    William Perry
    Neuropsychiatry and Behavioral Medicine Service, Department of Psychiatry, University of California San Diego, La Jolla 92093 8620, USA
    Am J Psychiatry 159:1375-81. 2002
  10. ncbi request reprint Schizophrenia patients demonstrate a dissociation on declarative and non-declarative memory tests
    W Perry
    University of California, Department of Psychiatry, 9500 Gilman Drive, La Yolla, San Diego, CA 92093 8620, USA
    Schizophr Res 46:167-74. 2000

Collaborators

Detail Information

Publications46

  1. pmc Quantifying over-activity in bipolar and schizophrenia patients in a human open field paradigm
    William Perry
    Department of Psychiatry, University of California, San Diego, La Jolla, CA 92093 8218, USA
    Psychiatry Res 178:84-91. 2010
    ..The current study extends our methodology for quantifying exploration and over-activity in a controlled laboratory setting and aids in assessing the overlap and distinguishing characteristics of BD and SCZ...
  2. pmc Beyond the numbers: expanding the boundaries of neuropsychology
    William Perry
    Department of Psychiatry, University of California, San Diego, CA 92093 8620, USA
    Arch Clin Neuropsychol 24:21-9. 2009
    ....
  3. ncbi request reprint Sensorimotor gating deficits in adults with autism
    William Perry
    Department of Psychiatry, University of California, San Diego, California, USA
    Biol Psychiatry 61:482-6. 2007
    ..Adults with autistic disorder (AD) exhibit clinical features of inhibitory deficits, such as restrictive and repetitive behaviors, that may be explained by deficits in sensorimotor gating...
  4. ncbi request reprint Neuropsychological test performance in patients co-infected with hepatitis C virus and HIV
    William Perry
    Hepatology Neurobehavioral Research Program, University of California, San Diego, CA 92103 8218, USA
    AIDS 19:S79-84. 2005
    ..To determine the effect of co-infection on neuropsychological performance in relatively healthy hepatitis C virus (HCV)-alone patients when compared with HCV/HIV-co-infected patients...
  5. ncbi request reprint A retrospective review of the neuropsychological test performance of physicians referred for medical infractions
    William Perry
    Department of Psychiatry, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093 8218, USA
    Arch Clin Neuropsychol 20:161-70. 2005
    ..Applying a neuropsychological framework to the assessment of physicians may uncover potential cognitive factors that contribute to medical practice errors...
  6. ncbi request reprint Prepulse inhibition in patients with non-psychotic major depressive disorder
    William Perry
    Department of Psychiatry, University of California San Diego, 200 West Arbor Drive, Mailcode 8218, San Diego, CA 92103 8218, USA
    J Affect Disord 81:179-84. 2004
    ..Therefore, we assessed PPI in non-psychotic MDD patients and compared their results to schizophrenia patients and non-patients...
  7. ncbi request reprint Let's call the whole thing off: a response to Dawes (2001)
    William Perry
    Department of Psychiatry, University of California, San Diego, 9500 Gilman Drive, La Jolla, California 92093 8218, USA
    Psychol Assess 15:582-5. 2003
    ..Thus, the conclusion presented in this Comment is that it is time for us to "call the whole thing off" and end the Rorschach controversy that has occupied so much recent attention and generated so few new ideas...
  8. ncbi request reprint The use of the Ego Impairment Index across the schizophrenia spectrum
    William Perry
    Department of Psychiatry, University of California, San Diego, La Jolla, CA 92093 8620, USA
    J Pers Assess 80:50-7. 2003
    ....
  9. ncbi request reprint Information processing deficits in acutely psychotic schizophrenia patients medicated and unmedicated at the time of admission
    William Perry
    Neuropsychiatry and Behavioral Medicine Service, Department of Psychiatry, University of California San Diego, La Jolla 92093 8620, USA
    Am J Psychiatry 159:1375-81. 2002
    ..The present study investigated the effects of antipsychotics on prepulse inhibition and startle habituation in acutely hospitalized patients with schizophrenia...
  10. ncbi request reprint Schizophrenia patients demonstrate a dissociation on declarative and non-declarative memory tests
    W Perry
    University of California, Department of Psychiatry, 9500 Gilman Drive, La Yolla, San Diego, CA 92093 8620, USA
    Schizophr Res 46:167-74. 2000
    ..The schizophrenia patients' dissociation on declarative vs. non-declarative memory tests is discussed in terms of possible underlying structural impairment...
  11. ncbi request reprint A multimethod approach to assessing perseverations in schizophrenia patients
    W Perry
    University of California, San Diego, Department of Psychiatry, La Jolla 92093 8620, USA
    Schizophr Res 33:69-77. 1998
    ..These data provide evidence that perseverative behavior is widely observed in schizophrenia patients using a variety of instruments. The authors discuss the benefit of using multiple measures of perseveration in schizophrenia research...
  12. ncbi request reprint Sensorimotor gating and thought disturbance measured in close temporal proximity in schizophrenic patients
    W Perry
    Department of Psychiatry, University of California, San Diego, USA
    Arch Gen Psychiatry 56:277-81. 1999
    ..To address this issue, sensorimotor gating and thought disturbance were measured in close temporal proximity, thus strengthening the evidence for the association of these 2 abnormalities in schizophrenic patients...
  13. ncbi request reprint Working memory in schizophrenia: transient "online" storage versus executive functioning
    W Perry
    Department of Psychiatry, University of California, San Diego, La Jolla 92093 8620, USA
    Schizophr Bull 27:157-76. 2001
    ..The importance of clearly identifying which distinct aspects of working memory are assessed is discussed...
  14. ncbi request reprint Self-monitoring enhances Wisconsin Card Sorting Test performance in patients with schizophrenia: performance is improved by simply asking patients to verbalize their sorting strategy
    W Perry
    University of California, San Diego, Department of Psychiatry, USA
    J Int Neuropsychol Soc 7:344-52. 2001
    ..Cumulatively, these data suggest that a simple instruction may enhance executive function and impact WCST performance in patients with schizophrenia...
  15. ncbi request reprint Incremental validity of the Ego Impairment Index: a re-examination of Dawes (1999)
    W Perry
    Department of Psychiatry, University of California, San Diego, 9500 Gilman Drive, La Jolla, California 92093 8218, USA
    Psychol Assess 13:403-7. 2001
    ..005) even after the 2 EII variables selected by Dawes and the measure of social competence were 1st entered into the equation. The results suggest that the EII adds meaningful information in the assessment of thought disturbance...
  16. ncbi request reprint Cognitive dysfunction in chronic hepatitis C: a review
    William Perry
    Department of Psychiatry, Hepatology Neurobehavioral Research Program, UCSD Liver Center, University of California, 200 West Arbor Drive, San Diego, CA 92108 8707, USA
    Dig Dis Sci 53:307-21. 2008
    ..Implications of these findings and directions for future work are discussed...
  17. ncbi request reprint Utility of the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS) in patients with end-stage liver disease awaiting liver transplant
    Scott Mooney
    Department of Psychiatry, University of California, San Diego, CA 92103 8212, USA
    Arch Clin Neuropsychol 22:175-86. 2007
    ..In summary, the RBANS appears to adequately characterize known patterns of cognitive dysfunction in ESLD patients...
  18. ncbi request reprint Neuropsychological impairment in patients with chronic hepatitis C
    Robin C Hilsabeck
    University of California, San Diego Medical Center, San Diego, CA, USA
    Hepatology 35:440-6. 2002
    ..Future studies need to determine the effect of this decrease in cognitive function on quality of life...
  19. ncbi request reprint Relationship of tinnitus questionnaires to depressive symptoms, quality of well-being, and internal focus
    Shannon K Robinson
    University of California San Diego, USA
    Int Tinnitus J 9:97-103. 2003
    ..37-.52; all p values < .01) but not with the PSCS. When controlling for the shared variance between tinnitus measures, the THQ independently predicted the HRSD, whereas the TRQ independently predicted the BDI...
  20. pmc Prepulse inhibition of startle in adults with ADHD
    David Feifel
    University of California San Diego, School of Medicine, Department of Psychiatry, San Diego, CA 92103 8218, USA
    J Psychiatr Res 43:484-9. 2009
    ..This distinction may be related to a relative sparing of pre-conscious attentional functions in ADHD compared to other disorders with PPI impairment...
  21. doi request reprint Performance of the hepatic encephalopathy scoring algorithm in a clinical trial of patients with cirrhosis and severe hepatic encephalopathy
    Tarek Hassanein
    Department of Medicine, University of California San Diego, 200 West Arbor Drive, San Diego, CA 92103 8423, USA
    Am J Gastroenterol 104:1392-400. 2009
    ..The grading of hepatic encephalopathy (HE) is based on a combination of indicators that reflect the state of consciousness, intellectual function, changes in behavior, and neuromuscular alterations seen in patients with liver failure...
  22. ncbi request reprint Introduction to the Hepatic Encephalopathy Scoring Algorithm (HESA)
    Tarek I Hassanein
    Department of Medicine, Hepatology Neurobehavioral Research Program, UCSD Liver Center, University of California, 200 West Arbor Drive, San Diego, CA 92108 8707, USA
    Dig Dis Sci 53:529-38. 2008
    ..The results also suggest HESA may be more sensitive to mental status impairment in the middle grades of HE than WHC. These findings suggest HESA holds promise as a multi-method approach to grading all levels of HE...
  23. pmc Heart rate variability in bipolar mania and schizophrenia
    Brook L Henry
    University of California San Diego, Department of Psychiatry, La Jolla, CA 92103 0851, United States
    J Psychiatr Res 44:168-76. 2010
    ..We recorded cardiac activity and assessed HRV in acutely hospitalized manic bipolar (BD) and schizophrenia (SCZ) patients compared to age- and gender-matched healthy comparison (HC) subjects...
  24. ncbi request reprint The category test perseveration, loss of set, and memory scales: three new scales and their relationship to executive functioning measures
    Arpi Minassian
    Department of Psychiatry, University of California, San Diego 92103 8620, USA
    Assessment 10:213-21. 2003
    ..Although future studies designed to test discriminant and convergent validity are warranted, these scales may be useful in determining specific aspects of impaired CT performance...
  25. pmc A reverse-translational study of dysfunctional exploration in psychiatric disorders: from mice to men
    William Perry
    Department of Psychiatry, University of California, San Diego, 9500 Gilman Dr, MC 0804, La Jolla, CA 92093 0804, USA
    Arch Gen Psychiatry 66:1072-80. 2009
    ..Exploration is fundamental to survival and is dysregulated in these 2 disorders. Although exploratory behavior in rodents has been widely studied, surprisingly little work has examined this critical function in humans...
  26. ncbi request reprint Adults with autism show increased sensitivity to outcomes at low error rates during decision-making
    Arpi Minassian
    Department of Psychiatry, University of California, San Diego, 200 West Arbor Drive, Mailcode 8620, San Diego, CA 92103 8620, USA
    J Autism Dev Disord 37:1279-88. 2007
    ..Thus, behavioral paradigms that provide frequent reinforcement may be helpful in modifying decision-making abilities in AD...
  27. pmc The relationship between sensorimotor gating and clinical improvement in acutely ill schizophrenia patients
    Arpi Minassian
    Department of Psychiatry, University of California, San Diego School of Medicine, USA
    Schizophr Res 89:225-31. 2007
    ..Our results suggest that PPI can be improved by short-term treatment, and that improvement in sensorimotor gating is associated with treatment-related improvement of symptoms of schizophrenia...
  28. ncbi request reprint Assessing disturbed thinking and cognition using the Ego Impairment Index in older schizophrenia patients: paranoid vs. nonparanoid distinction
    Lisa A Auslander
    Department of Psychiatry, University of California, San Diego, CA, USA
    Schizophr Res 53:199-207. 2002
    ..We compared thought-disturbance via the Rorschach-derived Ego Impairment Index (EII) between DSM-IV paranoid vs. nonparanoid (undifferentiated and disorganized) subtypes of older schizophrenia patients...
  29. ncbi request reprint Pupillary dilation to simple vs. complex tasks and its relationship to thought disturbance in schizophrenia patients
    Arpi Minassian
    Department of Psychiatry, University of California, 200 West Arbor Drive, Mailcode 8620, San Diego, CA 92103 8620, USA
    Int J Psychophysiol 52:53-62. 2004
    ..These findings support the 'resource limitations hypothesis' of schizophrenia and underscore the utility of a simultaneous paradigm when studying the relationship between attentional deficits and thought disturbance...
  30. pmc Effect of methamphetamine dependence on everyday functional ability
    Brook L Henry
    University of California San Diego, Department of Psychiatry, La Jolla, CA, United States
    Addict Behav 35:593-8. 2010
    ..We assessed the effect of METH dependence on everyday functioning using the UCSD Performance-Based Skills Assessment (UPSA-2), a performance-based measure designed to evaluate real-life skills...
  31. pmc Cross-species assessments of motor and exploratory behavior related to bipolar disorder
    Brook L Henry
    University of California San Diego, Department of Psychiatry, La Jolla, CA, USA
    Neurosci Biobehav Rev 34:1296-306. 2010
    ....
  32. ncbi request reprint Visual scanning deficits in schizophrenia and their relationship to executive functioning impairment
    Arpi Minassian
    Department of Psychiatry, University of California San Diego, 200 West Arbor Drive, Mailcode 8620, San Diego, CA 92103 8620, USA
    Schizophr Res 74:69-79. 2005
    ....
  33. ncbi request reprint Increased sensitivity to error during decision-making in bipolar disorder patients with acute mania
    Arpi Minassian
    Department of Psychiatry, University of California San Diego, 200 West Arbor Drive, Mailcode 8620, San Diego, CA 92103 8620, USA
    J Affect Disord 82:203-8. 2004
    ..In this study we examined whether BD patients with psychotic mania show altered patterns of decision-making as a function of the frequency of incorrect predictions or error rate...
  34. ncbi request reprint Inhibitory deficits in ocular motor behavior in adults with attention-deficit/hyperactivity disorder
    David Feifel
    Adult ADHD Program, Department of Psychiatry, University of California, San Diego, La Jolla, California, USA
    Biol Psychiatry 56:333-9. 2004
    ..The ability to suppress unwanted saccadic eye movements is mediated by prefrontal cortex-basal ganglia circuitry and thus constitutes a useful measure of inhibitory ability...
  35. pmc The quantitative assessment of motor activity in mania and schizophrenia
    Arpi Minassian
    University of California, Department of Psychiatry, San Diego, CA, USA
    J Affect Disord 120:200-6. 2010
    ..We used an ambulatory monitoring device to quantify motor activity in BD and schizophrenia (SCZ) patients in a novel exploratory paradigm, the human Behavioral Pattern Monitor (BPM)...
  36. pmc GBR 12909 administration as a mouse model of bipolar disorder mania: mimicking quantitative assessment of manic behavior
    Jared W Young
    Department of Psychiatry, University of California, San Diego, 9500 Gilman Drive MC 0804, La Jolla, CA 92093 0804, USA
    Psychopharmacology (Berl) 208:443-54. 2010
    ....
  37. ncbi request reprint Modifying the Rorschach Human Experience Variable to create the Human Representational Variable
    Donald J Viglione
    California School of Professional Psychology, San Diego Alliant International University, San Diego, CA 92131 1799, USA
    J Pers Assess 81:64-73. 2003
    ..Data presented here suggest that the HRV has improved psychometric properties compared to the HEV and that it is simpler to understand. Research recommendations and interpretive suggestions are also presented...
  38. pmc A reverse-translational approach to bipolar disorder: rodent and human studies in the Behavioral Pattern Monitor
    Jared W Young
    University of California San Diego, Department of Psychiatry, 9500 Gilman Dr, La Jolla, CA 92093 0603, USA
    Neurosci Biobehav Rev 31:882-96. 2007
    ..This unique approach to modeling BD provides an opportunity to identify the neurobiology underlying BD mania and test novel antimanic agents...
  39. ncbi request reprint Rapid oral loading of extended release divalproex in patients with acute mania
    Brian P Miller
    Neuropsychiatry and Behavioral Medicine Unit, University of California, San Diego Medical Center, San Diego, California 92103 8218, USA
    Gen Hosp Psychiatry 27:218-21. 2005
    ..Recently, an extended release formulation of divalproex sodium (divalproex ER) was approved for treatment of migraine headaches. This formulation may be a useful treatment option for patients with acute mania...
  40. pmc Implications of hepatitis C virus infection for behavioral symptoms and activities of daily living
    Carolina Posada
    San Diego State University University of California, San Diego Joint Doctoral Program in Clinical Psychology, San Diego, CA, USA
    J Clin Exp Neuropsychol 32:637-44. 2010
    ..These results show that a subset of HCV-infected individuals report clinically elevated behavioral symptoms. Clinical implications for the assessment and management of elevated behavioral symptoms in HCV are discussed...
  41. ncbi request reprint Refinements in the Rorschach Ego Impairment Index incorporating the human representational variable
    Donald J Viglione
    California School of Professional Psychology, Alliant International University, San Diego 92131 1799, USA
    J Pers Assess 81:149-56. 2003
    ..This was accomplished by recalculating the factor coefficients with a sample of 363 Rorschach protocols. We present additional validity data for the new EII-2. Research recommendations and interpretive guidelines are also presented...
  42. ncbi request reprint A method to optimize the response range while maintaining Rorschach Comprehensive System validity
    Kristin L Dean
    Department of Clinical Psychology, California School of Professional Psychology at Alliant International University, USA
    J Pers Assess 89:149-61. 2007
    ..The findings have clinical implications for protocol administration with thought-disordered populations that typically produce brief records...
  43. ncbi request reprint Cognitive functioning and psychiatric symptomatology in patients with chronic hepatitis C
    Robin C Hilsabeck
    Department of Neuropsychiatry and Behavioral Science, Texas Tech University Health Sciences Center, Lubbock, Texas 79430, USA
    J Int Neuropsychol Soc 9:847-54. 2003
    ....
  44. ncbi request reprint Biopsychosocial predictors of fatigue in chronic hepatitis C
    Robin C Hilsabeck
    Department of Neuropsychiatry and Behavioral Science, Texas Tech University Health Sciences Center, 3601 4th Street, STOP 8321, Lubbock, TX 79430, USA
    J Psychosom Res 58:173-8. 2005
    ..The objective of this study was to investigate the relationship of biopsychosocial variables to fatigue in patients with chronic hepatitis C (CHC) with the goal of identifying areas of possible intervention...
  45. ncbi request reprint Effect of interferon-alpha on cognitive functioning in patients with chronic hepatitis C
    Robin C Hilsabeck
    Department of Neuropsychiatry and Behavioral Science, Texas Tech University Health Sciences Center, Lubbock, Texas, USA
    J Int Neuropsychol Soc 11:16-22. 2005
    ..Additional research is needed to replicate these findings and to explore risk factors for susceptibility to IFN-alpha-induced effects...
  46. ncbi request reprint A process approach to verbal fluency in patients with schizophrenia
    Leeza M Maron
    Schizophr Res 68:105-6. 2004

Research Grants6

  1. Inhibitory Deficits in Mania and Hyperdopaminiergic Mice
    William Perry; Fiscal Year: 2004
    ..Such preclinical models, and the human measures essential to their validation, are critical to the future discovery of novel treatments of this condition. ..
  2. Inhibitory Deficits in Mania and Hyperdopaminiergic Mice
    William Perry; Fiscal Year: 2005
    ..Such preclinical models, and the human measures essential to their validation, are critical to the future discovery of novel treatments of this condition. ..
  3. Inhibitory Deficits in Mania and Hyperdopaminiergic Mice
    William Perry; Fiscal Year: 2006
    ..Such preclinical models, and the human measures essential to their validation, are critical to the future discovery of novel treatments of this condition. ..
  4. Inhibitory Deficits in Mania and Hyperdopaminiergic Mice
    William Perry; Fiscal Year: 2007
    ..Such preclinical models, and the human measures essential to their validation, are critical to the future discovery of novel treatments of this condition. ..
  5. INHIBITORY DEFICITS IN HUMAN AND ANIMAL MODELS OF BIPOLAR DISORDER
    WILLIAM contact PERRY; Fiscal Year: 2010
    ..Completion of this work will assist in understanding the underlying brain dysfunction of BD as well as assist in discovering and developing novel treatments. ..