NORA IRMA PERRONE BIZZOZERO

Summary

Affiliation: University of New Mexico
Country: USA

Publications

  1. ncbi request reprint Role of HuD in nervous system function and pathology
    Nora Perrone-Bizzozero
    Department of Neurosciences, University of New Mexico School of Medicine, Albuquerque, NM 87131, USA
    Front Biosci (Schol Ed) 5:554-63. 2013
  2. pmc Increased expression of axogenesis-related genes and mossy fibre length in dentate granule cells from adult HuD overexpressor mice
    Nora I Perrone-Bizzozero
    Departmemt of Neurosciences, University of New Mexico School of Medicine, Albuquerque, NM 87131, USA
    ASN Neuro 3:259-70. 2011
  3. ncbi request reprint Long-term treatment of rats with haloperidol: lack of an effect on brain N-acetyl aspartate levels
    Juan Bustillo
    Department of Psychiatry, University of New Mexico Health Sciences Center, Albuquerque, NM 87131 0001, USA
    Neuropsychopharmacology 31:751-6. 2006
  4. pmc Alterations in mossy fiber physiology and GAP-43 expression and function in transgenic mice overexpressing HuD
    Daniel C Tanner
    Department of Neurosciences, University of New Mexico HSC, Albuquerque, New Mexico 87106, USA
    Hippocampus 18:814-23. 2008
  5. ncbi request reprint Coordinated expression of HuD and GAP-43 in hippocampal dentate granule cells during developmental and adult plasticity
    Federico Bolognani
    Department of Cell Biology and Physiology, University of New Mexico School of Medicine, Albuquerque, NM 87131, USA
    Neurochem Res 32:2142-51. 2007
  6. ncbi request reprint Associative and spatial learning and memory deficits in transgenic mice overexpressing the RNA-binding protein HuD
    Federico Bolognani
    Department of Cell Biology and Physiology, University of New Mexico HSC, Albuquerque, NM 87131, USA
    Neurobiol Learn Mem 87:635-43. 2007
  7. ncbi request reprint In vivo post-transcriptional regulation of GAP-43 mRNA by overexpression of the RNA-binding protein HuD
    Federico Bolognani
    Department of Neurosciences, University of New Mexico School of Medicine, Albuquerque, NM 87131, USA
    J Neurochem 96:790-801. 2006
  8. ncbi request reprint Growth-associated protein 43 (GAP-43) and synaptophysin alterations in the dentate gyrus of patients with schizophrenia
    Jessie S Chambers
    Department of Neurosciences, University of New Mexico School of Medicine, 915 Camino de Salud NE, Albuquerque, NM 87131, USA
    Prog Neuropsychopharmacol Biol Psychiatry 29:283-90. 2005
  9. ncbi request reprint Poly(A) tail length-dependent stabilization of GAP-43 mRNA by the RNA-binding protein HuD
    Andrea C Beckel-Mitchener
    Department of Neurosciences, University of New Mexico School of Medicine, Albuquerque, New Mexico 87131 5223, USA
    J Biol Chem 277:27996-8002. 2002
  10. ncbi request reprint Changes in protein kinase C (PKC) activity, isozyme translocation, and GAP-43 phosphorylation in the rat hippocampal formation after a single-trial contextual fear conditioning paradigm
    Elizabeth Young
    Department of Neurosciences, University of New Mexico School of Medicine, Albuquerque 87131 5223, USA
    Hippocampus 12:457-64. 2002

Research Grants

  1. MECHANISMS OF CONTROL OF THE GAP-43 GENE
    Nora Perrone Bizzozero; Fiscal Year: 2004
  2. Mechanisms of Post-Transcriptional Control of Neuronal mRNAs
    Nora Perrone Bizzozero; Fiscal Year: 2007
  3. ARND--IMPACT ON SYNAPTIC PLASTICITY MECHANISMS
    Nora Perrone Bizzozero; Fiscal Year: 2002
  4. MECHANISMS OF CONTROL OF THE GAP-43 GENE
    Nora Perrone Bizzozero; Fiscal Year: 1999
  5. Mechanisms of Post-Transcriptional Control of Neuronal mRNAs
    NORA IRMA PERRONE BIZZOZERO; Fiscal Year: 2010

Collaborators

  • John Lauriello
  • J Bustillo
  • Gregory J Moore
  • ELIZABETH ANN YOUNG
  • DANIEL SAVAGE
  • Shenfeng Qiu
  • Federico Bolognani
  • Nora I Perrone-Bizzozero
  • Daniel C Tanner
  • Jessie S Chambers
  • Nora Perrone-Bizzozero
  • Julie Deschenes-Furry
  • Rodrigo D Paz
  • Rachael L Neve
  • Rafael Galindo
  • Catherine L Smith
  • Andrea C Beckel-Mitchener
  • Clark W Bird
  • Joanna Mounce
  • Edwin J Weeber
  • L Donald Partridge
  • Robin J Parks
  • Kambiz Mousavi
  • Bernard J Jasmin
  • Sami Z Daoud
  • Robert Conley
  • Rosalinda Roberts
  • Nancy C Andreasen
  • Deirdre Thomas
  • Linda Saland
  • Rownak Afroz
  • Shanti Frausto
  • Christina Wolff
  • Henry M Furneaux
  • Ann W Githinji
  • Karina Meiri
  • Richard W Burry
  • Gary J Bassell
  • Kevin K Caldwell
  • Rebecca Keller
  • Angel Miera

Detail Information

Publications18

  1. ncbi request reprint Role of HuD in nervous system function and pathology
    Nora Perrone-Bizzozero
    Department of Neurosciences, University of New Mexico School of Medicine, Albuquerque, NM 87131, USA
    Front Biosci (Schol Ed) 5:554-63. 2013
    ..This review will focus on the involvement of HuD in nervous system function and pathology...
  2. pmc Increased expression of axogenesis-related genes and mossy fibre length in dentate granule cells from adult HuD overexpressor mice
    Nora I Perrone-Bizzozero
    Departmemt of Neurosciences, University of New Mexico School of Medicine, Albuquerque, NM 87131, USA
    ASN Neuro 3:259-70. 2011
    ..These results support the notion that HuD stabilizes a number of developmentally regulated mRNAs in DGCs, resulting in increased axonal elongation...
  3. ncbi request reprint Long-term treatment of rats with haloperidol: lack of an effect on brain N-acetyl aspartate levels
    Juan Bustillo
    Department of Psychiatry, University of New Mexico Health Sciences Center, Albuquerque, NM 87131 0001, USA
    Neuropsychopharmacology 31:751-6. 2006
    ..The documented lower NAA in chronically treated schizophrenia patients is most likely not a simple effect of antipsychotic medications...
  4. pmc Alterations in mossy fiber physiology and GAP-43 expression and function in transgenic mice overexpressing HuD
    Daniel C Tanner
    Department of Neurosciences, University of New Mexico HSC, Albuquerque, New Mexico 87106, USA
    Hippocampus 18:814-23. 2008
    ....
  5. ncbi request reprint Coordinated expression of HuD and GAP-43 in hippocampal dentate granule cells during developmental and adult plasticity
    Federico Bolognani
    Department of Cell Biology and Physiology, University of New Mexico School of Medicine, Albuquerque, NM 87131, USA
    Neurochem Res 32:2142-51. 2007
    ..Altogether, these results demonstrate that HuD plays a role in the post-transcriptional control of GAP-43 mRNA in dentate granule cells during developmental and adult plasticity...
  6. ncbi request reprint Associative and spatial learning and memory deficits in transgenic mice overexpressing the RNA-binding protein HuD
    Federico Bolognani
    Department of Cell Biology and Physiology, University of New Mexico HSC, Albuquerque, NM 87131, USA
    Neurobiol Learn Mem 87:635-43. 2007
    ..We conclude that posttranscriptional regulation of gene expression by stabilization of specific mRNAs may have to be restricted temporally and spatially for proper acquisition and storage of memories...
  7. ncbi request reprint In vivo post-transcriptional regulation of GAP-43 mRNA by overexpression of the RNA-binding protein HuD
    Federico Bolognani
    Department of Neurosciences, University of New Mexico School of Medicine, Albuquerque, NM 87131, USA
    J Neurochem 96:790-801. 2006
    ..In conclusion, our results demonstrate that HuD overexpression is sufficient to increase GAP-43 mRNA stability in vivo...
  8. ncbi request reprint Growth-associated protein 43 (GAP-43) and synaptophysin alterations in the dentate gyrus of patients with schizophrenia
    Jessie S Chambers
    Department of Neurosciences, University of New Mexico School of Medicine, 915 Camino de Salud NE, Albuquerque, NM 87131, USA
    Prog Neuropsychopharmacol Biol Psychiatry 29:283-90. 2005
    ....
  9. ncbi request reprint Poly(A) tail length-dependent stabilization of GAP-43 mRNA by the RNA-binding protein HuD
    Andrea C Beckel-Mitchener
    Department of Neurosciences, University of New Mexico School of Medicine, Albuquerque, New Mexico 87131 5223, USA
    J Biol Chem 277:27996-8002. 2002
    ..We conclude that HuD stabilizes the GAP-43 mRNA through a mechanism that is dependent on the length of the poly(A) tail and involves changes in its affinity for the mRNA...
  10. ncbi request reprint Changes in protein kinase C (PKC) activity, isozyme translocation, and GAP-43 phosphorylation in the rat hippocampal formation after a single-trial contextual fear conditioning paradigm
    Elizabeth Young
    Department of Neurosciences, University of New Mexico School of Medicine, Albuquerque 87131 5223, USA
    Hippocampus 12:457-64. 2002
    ....
  11. ncbi request reprint Fetal alcohol exposure alters GAP-43 phosphorylation and protein kinase C responses to contextual fear conditioning in the hippocampus of adult rat offspring
    Daniel C Tanner
    Department of Neurosciences, University of New Mexico, Albuquerque, New Mexico, USA
    Alcohol Clin Exp Res 28:113-22. 2004
    ..Drawing on these observations, we hypothesized that FAE manifests its cognitive impairment by disrupting PKC activation and membrane translocation, thereby decreasing GAP-43 phosphorylation and function...
  12. ncbi request reprint RNA-protein interactions and control of mRNA stability in neurons
    Federico Bolognani
    Department of Cell Biology and Physiology, University of New Mexico School of Medicine, Albuquerque, New Mexico, USA
    J Neurosci Res 86:481-9. 2008
    ..In this Mini-Review, we briefly discuss the general mechanisms of control of mRNA turnover and present evidence supporting the importance of these mechanisms in the expression of an increasing number of neuronal genes...
  13. ncbi request reprint GAP-43 mRNA in growth cones is associated with HuD and ribosomes
    Catherine L Smith
    Department of Neuroscience, College of Medicine and Public Health, The Ohio State University, Columbus, Ohio 43210 1239, USA
    J Neurobiol 61:222-35. 2004
    ..Together, these results demonstrate that many of the components necessary for GAP-43 mRNA translation/stabilization are present within growth cones...
  14. ncbi request reprint The RNA-binding protein HuD binds acetylcholinesterase mRNA in neurons and regulates its expression after axotomy
    Julie Deschenes-Furry
    Department of Cellular and Molecular Medicine and Centre for Neuromuscular Disease, University of Ottawa, Ottawa, Ontario, Canada K1H 8M5
    J Neurosci 27:665-75. 2007
    ..Together, the results of this study demonstrate that AChE expression in neurons of the rat SCG is regulated via post-transcriptional mechanisms that involve the AU-rich element and HuD...
  15. ncbi request reprint Dendritic localization of the RNA-binding protein HuD in hippocampal neurons: association with polysomes and upregulation during contextual learning
    Federico Bolognani
    Department of Neurosciences, School of Medicine, University of New Mexico, Albuquerque, NM 87131 5223, USA
    Neurosci Lett 371:152-7. 2004
    ..Our findings suggest that HuD plays a role in synaptic plasticity mechanisms stabilizing mRNAs associated with ribosomes both in the soma and dendrites of hippocampal neurons...
  16. ncbi request reprint Increased expression of activity-dependent genes in cerebellar glutamatergic neurons of patients with schizophrenia
    Rodrigo D Paz
    Department of Neurosciences, University of New Mexico School of Medicine, Albuquerque, 87131, USA
    Am J Psychiatry 163:1829-31. 2006
    ..The purpose of this study was to evaluate the functional state of glutamatergic neurons in the cerebellar cortex of patients with schizophrenia...
  17. ncbi request reprint Prenatal ethanol exposure reduces mGluR5 receptor number and function in the dentate gyrus of adult offspring
    Rafael Galindo
    Department of Neurosciences, University of New Mexico School of Medicine, Albuquerque, New Mexico 87131 0001, USA
    Alcohol Clin Exp Res 28:1587-97. 2004
    ....
  18. ncbi request reprint Altered myelination of the hippocampal formation in subjects with schizophrenia and bipolar disorder
    Jessie S Chambers
    915 Camino de Salud NE, Department of Neurosciences, University of New Mexico School of Medicine, Albuquerque, NM 87131, USA
    Neurochem Res 29:2293-302. 2004
    ..Our results demonstrate an interaction between gender, mental illness, and myelination, and may be related to cognitive deficits seen in schizophrenia and bipolar disorder...

Research Grants21

  1. MECHANISMS OF CONTROL OF THE GAP-43 GENE
    Nora Perrone Bizzozero; Fiscal Year: 2004
    ..abstract_text> ..
  2. Mechanisms of Post-Transcriptional Control of Neuronal mRNAs
    Nora Perrone Bizzozero; Fiscal Year: 2007
    ....
  3. ARND--IMPACT ON SYNAPTIC PLASTICITY MECHANISMS
    Nora Perrone Bizzozero; Fiscal Year: 2002
    ..Ultimately, this information will help design better therapeutic strategies to overcome behavioral and cognitive deficits in children affected with Alcohol Related Neurodevelopmental Disorders (ARND). ..
  4. MECHANISMS OF CONTROL OF THE GAP-43 GENE
    Nora Perrone Bizzozero; Fiscal Year: 1999
    ....
  5. Mechanisms of Post-Transcriptional Control of Neuronal mRNAs
    NORA IRMA PERRONE BIZZOZERO; Fiscal Year: 2010
    ..abstract_text> ..