Research Topics
| W M PerlsteinSummaryAffiliation: University of Florida Country: USA Publications
Research Grants
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Detail Information
Publications
Dissociation in human prefrontal cortex of affective influences on working memory-related activityWilliam M Perlstein
Department of Clinical and Health Psychology and McKnight Brain Institute, University of Florida, Gainesville, FL 32610, USA
Proc Natl Acad Sci U S A 99:1736-41. 2002..Findings suggest a conceptualization of DLPFC and its involvement in WM that takes into account a role for affective parameters...
Prepulse effects as a function of cortical projection systemW M Perlstein
Department of Clinical and Health Psychology, University of Florida, HSC, P O Box 100165, Gainesville, FL 32610, USA
Biol Psychol 56:83-111. 2001..Results show that prestimulus inhibition of ERPs is not due to intrinsic refractoriness and that pairing differentially affects ERPs associated with modality specific and nonspecific projection systems...
Temporal dissociation of components of cognitive control dysfunction in severe TBI: ERPs and the cued-Stroop taskWilliam M Perlstein
Department of Clinical and Health Psychology, HSC Box 100165, University of Florida, Gainesville, FL 32610, USA
Neuropsychologia 44:260-74. 2006....
Parametric manipulation of working memory load in traumatic brain injury: behavioral and neural correlatesWilliam M Perlstein
Department of Clinical and Health Psychology, University of Florida, Gainesville, Florida 32610, USA
J Int Neuropsychol Soc 10:724-41. 2004..Overall, results demonstrate that individuals with moderate-to-severe TBI exhibit WM deficits that are associated with dysfunction within a distributed network of brain regions that support verbally mediated WM...
Steady-state visual evoked potentials reveal frontally-mediated working memory activity in humansWilliam M Perlstein
Department of Clinical and Health Psychology, University of Florida, Gainesville, FL 32610, USA
Neurosci Lett 342:191-5. 2003..Frontal WM-related SSVEP power correlated selectively with task performance. These results demonstrate the utility of SSVEPs for studying representational aspects of cognition...
Relation of prefrontal cortex dysfunction to working memory and symptoms in schizophreniaW M Perlstein
Department of Clinical and Health Psychology and Psychiatry, University of Florida, Gainesville 32610, USA
Am J Psychiatry 158:1105-13. 2001....
The dynamic mechanisms of placebo induced analgesia: Evidence of sustained and transient regional involvementJason G Craggs
Department of Clinical and Health Psychology, College of Health Professions, HPNP, Gainesville, FL 32610 0165, USA
Pain 139:660-9. 2008..Identifying brain regions associated with pain-modulation with different temporal profiles is consistent with the multidimensionality of PA and highlights the need for continued investigation of this construct...
Performance monitoring, error processing, and evaluative control following severe TBIMichael J Larson
Department of Clinical and Health Psychology, University of Florida, Gainesville, Florida 32610, USA
J Int Neuropsychol Soc 13:961-71. 2007..Implications for future research and potential clinical application as well as potential limitations in conducting electrophysiological research in neurologically-impaired populations are discussed...
Affective context-induced modulation of the error-related negativityMichael J Larson
Department of Clinical and Health Psychology, University of Florida, Gainesville, Florida 32610, USA
Neuroreport 17:329-33. 2006..Findings support the hypothesis that affective factors influence the error-related negativity, potentially reflecting an affective mismatch associated with performance monitoring...
Reward context sensitivity impairment following severe TBI: an event-related potential investigationMichael J Larson
Department of Clinical and Health Psychology, University of Florida, Gainesville, Florida 32610, USA
J Int Neuropsychol Soc 13:615-25. 2007..Findings implicate an electrophysiological marker of impaired reward context sensitivity following severe TBI...
Age-related changes in word retrieval: role of bilateral frontal and subcortical networksChristina E Wierenga
Department of Veterans Affairs Rehabilitation Research and Development, Brain Rehabilitation Research Center at the Malcom Randall, VA Medical Center, Gainesville, FL 32610, USA
Neurobiol Aging 29:436-51. 2008..Findings are discussed in the context of possible compensatory mechanisms invoked to maintain performance in healthy aging, and suggest that increased involvement of the right hemisphere is not universally beneficial to performance...
Placebo analgesia is accompanied by large reductions in pain-related brain activity in irritable bowel syndrome patientsDonald D Price
Department of Oral and Maxillofacial Surgery, University of Florida, Gainesville, FL 32610, USA
Pain 127:63-72. 2007..Although many factors influence placebo analgesia, it is accompanied by reduction in pain processing within the brain in clinically relevant conditions...
Brain activity related to temporal summation of C-fiber evoked painRoland Staud
Department of Medicine, McKnight Brain Institute, University of Florida, Gainesville, FL 32610, USA
Pain 129:130-42. 2007....
Cognitive control impairments in traumatic brain injuryMichael J Larson
Department of Clinical Psychology, University of Florida, Gainesville, FL 32610, USA
J Clin Exp Neuropsychol 28:968-86. 2006..Thus, patients with M/S TBI evidence cognitive control dysfunction in the processing and active maintenance of context representations...
Functional brain interactions that serve cognitive-affective processing during pain and placebo analgesiaJason G Craggs
Clinical and Health Psychology, University of Florida, Gainesville, FL 32610, USA
Neuroimage 38:720-9. 2007..Although it is likely that placebo analgesia results partly from afferent inhibition of a nociceptive signal, the mechanisms likely involve the interaction of a cognitive-affective network with input from both hemispheres...
Cognitive control in closed head injury: context maintenance dysfunction or prepotent response inhibition deficit?Paul J Seignourel
Department of Clinical and Health Psychology, University of Florida, Gainesville, FL 32610, USA
Neuropsychology 19:578-90. 2005..Thus, context maintenance could be a useful framework for characterizing cognitive control deficits in CHI...
Brain activity associated with slow temporal summation of C-fiber evoked pain in fibromyalgia patients and healthy controlsRoland Staud
Department of Medicine, McKnight Brain Institute, University of Florida, Gainesville, FL 32610, United States
Eur J Pain 12:1078-89. 2008..These results suggest that enhanced neural mechanisms of TSSP in FM are reflected at all pain related brain areas, including posterior thalamus, and are not the result of selective enhancement at cortical levels...
Neural substrates of object identification: Functional magnetic resonance imaging evidence that category and visual attribute contribute to semantic knowledgeChristina E Wierenga
Department of Veterans Affairs Rehabilitation Research and Development, Brain Rehabilitation Research Center at the Malcom Randall VA Medical Center, Gainesville, Florida, USA
J Int Neuropsychol Soc 15:169-81. 2009..Taken together, results support distinctions in the role of visual attributes and category in semantic representation...
Widespread hyperalgesia in irritable bowel syndrome is dynamically maintained by tonic visceral impulse input and placebo/nocebo factors: evidence from human psychophysics, animal models, and neuroimagingDonald D Price
Department of Oral Surgery, University of Florida College of Dentistry, Gainesville, Florida, USA
Neuroimage 47:995-1001. 2009..This explanatory model may be relevant to other persistent pain conditions...
Prefrontal cortex dysfunction mediates deficits in working memory and prepotent responding in schizophreniaWilliam M Perlstein
Department of Clinical and Health Psychology and the McKnight Brain Institute, University of Florida, Gainesville, 32610, USA
Biol Psychiatry 53:25-38. 2003..Findings are consistent with the operation of a single underlying PFC-mediated cognitive control mechanism and with physiologic dysfunction of the dorsolateral PFC in schizophrenic patients reflecting impairments in this mechanism...
Research Grants
- SPATIO-TEMPORAL IMAGING OF EMOTION AND FEARWILLIAM PERLSTEIN; Fiscal Year: 2004..Completion of this award would place the candidate in the position to continue programmatic research along these lines and provide a unique contribution to the cognitive neuroscience study of emotion and its disorders. ..
- Cognitive Control Dysfunction: Acute Closed Head InjuryWILLIAM PERLSTEIN; Fiscal Year: 2005....
