Research Topics
| Jonathan PerkinsSummaryAffiliation: University of Washington Country: USA Publications
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Detail Information
Publications
Morphologic and histologic outcomes of tongue reduction surgery in an animal modelJonathan A Perkins
Division of Pediatric Otolaryngology, Children s Hospital and Regional Medical Center, Seattle, WA 98105 0371, USA
Otolaryngol Head Neck Surg 139:291-297. 2008..To describe the effect of anterior tongue reduction surgery on tongue size, morphology, and histology...
Relational databases for rare disease study: application to vascular anomaliesJonathan A Perkins
Children s Hospital and Regional Medical Center, Division of Otolaryngology Head and Neck Surgery, Seattle, WA 98105 0371, USA
Arch Otolaryngol Head Neck Surg 134:62-6. 2008..The rarity of these lesions places a premium on coordinated studies among multiple participant sites...
Clinical outcomes in lymphocytopenic lymphatic malformation patientsJonathan A Perkins
Division of Pediatric Otolaryngology, Children s Hospital and Regional Medical Center, Seattle, Washington, USA
Lymphat Res Biol 5:169-74. 2007..To determine if lymphocytopenia in patients with lymphatic malformation (LM) is associated with rates of infection and poor clinical outcomes...
Clinical and radiographic findings in children with spontaneous lymphatic malformation regressionJonathan A Perkins
Division of Pediatric Otolaryngology, Children s Hospital and Regional Medical Center, Seattle, WA 98105 0371, USA
Otolaryngol Head Neck Surg 138:772-7. 2008..Evaluate clinical and radiographic characteristics of spontaneously regressing lymphatic malformations ("lesions")...
Airway procedures and hemangiomas: treatment patterns and outcome in U.S. pediatric hospitalsJonathan A Perkins
Division of Pediatric Otolaryngology Head and Neck Surgery, Seattle Children s Hospital, 4800 Sand Point Way N E, Seattle, WA 98105, USA
Int J Pediatr Otorhinolaryngol 73:1302-7. 2009..Characterize and compare care in children with hemangiomas, who do or do not undergo airway procedures...
Emerging concepts in airway infantile hemangioma assessment and managementJonathan A Perkins
Division of Pediatric Otolaryngology and Department of Otolaryngology Head and Neck Surgery, Seattle Children s Hospital, Seattle, WA 98105 0371, USA
Otolaryngol Head Neck Surg 141:207-212. 2009..The purpose of this study was to evaluate changes in airway infantile hemangioma treatment...
Overview of macroglossia and its treatmentJonathan A Perkins
Division of Pediatric Otolaryngology, Seattle Children s Hospital, Department of Otolaryngology Head and Neck Surgery, University of Washington, Seattle, WA 98105 0371, USA
Curr Opin Otolaryngol Head Neck Surg 17:460-5. 2009..To discuss current literature regarding the diagnosis, assessment and treatment of macroglossia in pediatric patients...
Proposal for staging airway hemangiomasJonathan A Perkins
Division of Pediatric Otolaryngology, Seattle Children s Hospital, Seattle, WA 98105 0371, USA
Otolaryngol Head Neck Surg 141:516-521. 2009..To describe a method of airway infantile hemangioma staging using standardized assessment of airway narrowing, and hemangioma location and volume, as determined with endoscopy and CT angiography...
Lymphatic malformations: current cellular and clinical investigationsJonathan A Perkins
Division of Pediatric Otolaryngology Head and Neck Surgery, Seattle Children s Hospital, Seattle, WA 98105 0371, USA
Otolaryngol Head Neck Surg 142:789-94. 2010..Summarize current knowledge of lymphatic malformation development, biology, and clinical outcome measures...
Three-dimensional CT angiography imaging of vascular tumors of the head and neckJonathan A Perkins
Division of Pediatric Otolaryngology, Department of Otolaryngology Head and Neck Surgery, University of Washington, 4800 Sand Point Way N E G 0035, Seattle, WA 98105 0371, USA
Int J Pediatr Otorhinolaryngol 69:319-25. 2005..To evaluate the utility of three-dimensional (3D) computerized tomography angiography (CTA) in head and neck vascular anomalies...
Lymphatic malformations: review of current treatmentJonathan A Perkins
Division of Pediatric Otolaryngology Head and Neck Surgery, Seattle Children s Hospital, Seattle, WA 98105 0371, USA
Otolaryngol Head Neck Surg 142:795-803, 803.e1. 2010..Summarize current knowledge of lymphatic malformation medical, sclerotherapy, and surgical treatment; and highlight areas of treatment controversy and treatment difficulty that need improvement...
Microdissection needle tonsillectomy and postoperative pain: a pilot studyJonathan Perkins
Division of Pediatric Otolaryngology, Children s Hospital Regional Medical Center, MS 6E 1, 4800 Sand Point Way NE, PO Box 5371, Seattle, WA 98105 0371, USA
Arch Otolaryngol Head Neck Surg 129:1285-8. 2003..To determine whether microdissection needle cautery for tonsillectomy results in decreased postoperative pain when compared with standard electrocautery...
Bacterial biofilm presence in pediatric tracheotomy tubesJonathan Perkins
Division of Pediatric Otolaryngology, Children s Hospital and Regional Medical Center, Seattle, WA 98105 0371, USA
Arch Otolaryngol Head Neck Surg 130:339-43. 2004..To determine whether bacterial biofilms are present on pediatric tracheotomy tubes...
Laryngeal anatomic differences in pediatric patients with severe laryngomalaciaScott C Manning
Department of Otolaryngology, University of Washington, Seattle, WA 98105, USA
Arch Otolaryngol Head Neck Surg 131:340-3. 2005..To compare the aryepiglottic (AE) length in pediatric patients who have severe laryngomalacia (SL) and are undergoing aryepiglottoplasty with the AE length of a convenience sample of control patients without laryngomalacia...
Histopathologic and immunophenotypic profile of subglottic hemangioma: multicenter studyArunkumar N Badi
Division of Pediatric Otolaryngology, Medical College of Wisconsin, Children s Hospital of Wisconsin, 9000 W Wisconsin Avenue, Milwaukee, WI 53226, USA
Int J Pediatr Otorhinolaryngol 73:1187-91. 2009..We present the largest, multi-institutional study, to date, with immunophenotypic characterization of SGH...
Endoscopic posterior cricoid split and rib grafting in 10 childrenAndrew F Inglis
Department of Otolaryngology Head and Neck Surgery, University of Washington, Children s Hospital and Regional Medical Center, Seattle 98105, USA
Laryngoscope 113:2004-9. 2003..To report our experience with endoscopic posterior cricoid split and rib graft insertion (EPCS/RG) in children with posterior glottic (PGS) and subglottic stenosis (SGS)...
Ultrasound-guided endovenous diode laser in the treatment of congenital venous malformations: preliminary experienceManrita K Sidhu
Department of Radiology, Children s Hospital and Regional Medical Center, 4800 Sand Point Way NE, R5438 1, Seattle, WA 98105, USA
J Vasc Interv Radiol 16:879-84. 2005..One patient had a self-limited mucosal tongue base ulcer. In this small series of patients, endovenous laser treatment of venous malformations was effective during short-term follow-up...
Diagnostic and surgical challenges in the pediatric skull baseScott C Manning
Department of Otolaryngology Head and Neck Surgery, University of Washington, 4800 Sand Point Way NE, Seattle, WA 98105, USA
Otolaryngol Clin North Am 38:773-94. 2005..Pediatric patients present special challenges because of their smaller anatomy, but potential gains in reduced morbidity make improvements in skull base approaches well worth pursuing...
Lymphocytopenia in children with lymphatic malformationRichard M Tempero
Department of Otolaryngology-Head and Neck Surgery, Division of Genetics and Developmental Medicine, University of Washington, Seattle, WA 98105, USA
Arch Otolaryngol Head Neck Surg 132:93-7. 2006..Although the relationship between lymphocytopenia and infection was not addressed in this study, the recognition of lymphocytopenia in patients with LM may have important clinical and prognostic implications...
Internal kinematics of the tongue following volume reductionVolodymyr Shcherbatyy
Department of Orthodontics, University of Washington, Seattle, Washington 98195 3446, USA
Anat Rec (Hoboken) 291:886-93. 2008..This compensatory effect, however, diminishes during stimulation of the hypoglossal nerve and individual tongue muscles...
Functional loads of the tongue and consequences of volume reductionZi Jun Liu
Department of Orthodontics, University of Washington, Seattle, WA 98195, USA
J Oral Maxillofac Surg 66:1351-61. 2008..This study was conducted to evaluate functional loads of the tongue on its surrounding bones and investigate how tongue volume reduction affects these loads...
Quantitative computed tomographic scan and polysomnographic analysis of patients with syndromic midface hypoplasia before and after Le Fort III distraction advancementRussell E Ettinger
Craniofacial Center, Seattle Children s Hospital, Seattle, Wash 98105, USA
Plast Reconstr Surg 127:1612-9. 2011..The purpose of this study was to relate changes in maxillary position to changes in obstructive sleep apnea measures on polysomnography in a consecutive series of patients...
Endoscopic repair of a rare basioccipital meningocele associated with recurrent meningitisAndrew L Ko
Department of Neurological Surgery, University of Washington School of Medicine, Seattle, Washington 98105, USA
J Neurosurg Pediatr 6:188-92. 2010..Note that recurrent meningitis in the setting of a skull base defect may indicate the presence of other congenital anomalies that will necessitate multidisciplinary care for a patient's long-term well-being...
PHACES syndrome: otolaryngic considerations in recognition and managementEmily F Rudnick
Department of Otolaryngology Head and Neck Surgery, University of Washington, Seattle, Washington, USA
Int J Pediatr Otorhinolaryngol 73:281-8. 2009..To describe the otolaryngic manifestations of PHACES and evaluate current diagnostic and management principles for these patients...
Effects of tongue volume reduction on craniofacial growth: A longitudinal study on orofacial skeletons and dental archesZi Jun Liu
Department of Orthodontics, School of Dentistry, University of Washington, P O Box 357446, Seattle, WA 98195, USA
Arch Oral Biol 53:991-1001. 2008..The mandible, in particular its symphysis portion, and the anterior dental arch width are most affected. These effects may in part contribute to the decrease of functional loads in the anterior mouth by a volume-reduced tongue...
Plastic laryngeal foreign bodies in children: a diagnostic challengeDavid C Bloom
Department of Otolaryngology, Head and Neck Surgery University of Washington, Division of Pediatric Otolaryngology Children's Hospital and Regional Medical Center, Seattle, 98105, USA
Int J Pediatr Otorhinolaryngol 69:657-62. 2005..Laryngeal foreign bodies should be in the differential diagnosis of all children presenting with atypical upper respiratory complaints especially if a history suggestive of witnessed aspiration and dysphonia can be obtained...
Tracheotomy in pediatric patients: a national perspectiveCharlotte W Lewis
Child Health Institute, University of Washington, Seattle 98195 4920, USA
Arch Otolaryngol Head Neck Surg 129:523-9. 2003..Given the complexity of health care that these patients subsequently require, monitoring the performance of this procedure and patient outcomes across the diverse US health care system is warranted...
A comparison of nasendoscopy and multiview videofluoroscopy in assessing velopharyngeal insufficiencyDerek J Lam
Department of Otolaryngology Head and Neck Surgery, University of Washington Medical Center, Box 356515, 1959 NE Pacific Street, Seattle, WA 98195, USA
Otolaryngol Head Neck Surg 134:394-402. 2006..1) To compare nasendoscopy (NE) and multiview fluoroscopy (MVF) in assessing velopharyngeal gap size; and 2) to determine the relationship between these assessments and velopharyngeal insufficiency (VPI) severity...
Sleep disturbances in 22q11.2 deletion syndrome: a case with obstructive and central sleep apneaCarrie L Heike
Department of Pediatrics, Division of Craniofacial Medicine, University of Washington and Children s Hospital and Regional Medical Center, Seattle, Washington, USA
Cleft Palate Craniofac J 44:340-6. 2007..She also had central sleep apnea, initially attributed to spinal cord impingement from cervical instability. Posterior cervical fusion was associated with a decrease in the number of central apneic events...
Somatostatin treatment of massive lymphorrhea following excision of a lymphatic malformationDaniel W Suver
University of Washington Medical School, University of Washington, Seattle, WA 98195, USA
Int J Pediatr Otorhinolaryngol 68:845-50. 2004..Based on this report and a review of the available literature, we advocate the early consideration of somatostatin and its analogues in the control of lymphorrhea...
Management of airway hemangiomasKarthik Balakrishnan
Department of Otolaryngology, University of Washington, Seattle Children s Hospital, 1959 NE Pacific Street, BB1165, UWMC Box 356515, Seattle, WA 98195 6515, USA
Expert Rev Respir Med 4:455-62. 2010..The article is divided into discussions of airway infantile hemangioma in general, medical therapy and surgical therapy. It concludes with predictions about the near future of airway infantile hemangioma research and therapy...
Management of lymphatic malformationsDavid C Bloom
Department of Otolaryngology/Head and Neck Surgery University of Washington, Division of Pediatric Otolaryngology Children's Hospital and Regional Medical Center, Seattle, Washington 98105, USA
Curr Opin Otolaryngol Head Neck Surg 12:500-4. 2004....
Similar histologic features and immunohistochemical staining in microcystic and macrocystic lymphatic malformationsEunice Y Chen
Division of Pediatric Otolaryngology Head and Neck Surgery, Children s Hospital and Regional Medical Center, Seattle, Washington 98105 0371, USA
Lymphat Res Biol 7:75-80. 2009..In this study, we describe the histologic features and expression of lymphatic endothelial markers in microcystic and macrocystic lymphatic malformations and correlate clinical data with histologic and immunohistochemical data...
Polymerase chain reaction for pathogen identification in persistent pediatric cervical lymphadenitisPeter Choi
Department of Otolaryngology Head and Neck Surgery, University of Washington, Seattle, WA, USA
Arch Otolaryngol Head Neck Surg 135:243-8. 2009..To study routine culture-negative persistent cervical lymphadenitis in children treated surgically during a 10-year period (December 26, 1997, to October 1, 2007) at a single institution...
Plasmacytoid dendritic cells and interferon levels are increased in lymphatic malformationsJo Nadine Fleming
Department of Pathology, University of Washington, Seattle, WA, USA
Otolaryngol Head Neck Surg 139:671-676. 2008..Describe the presence of plasmacytoid dendritic cells and type 1 interferon and the activation of interferon signaling pathway in lymphatic malformations...
Gorham Stout syndrome (disappearing bone disease): two additional case reports and a review of the literatureSamson Lee
Department of Otolaryngology-Head and Neck Surgery, University of Washington, 1959 N.E. Pacific Street, Seattle, WA 98195-6515, USA
Arch Otolaryngol Head Neck Surg 129:1340-3. 2003..In this clinical report, we describe 2 additional cases of Gorham-Stout syndrome affecting the maxillofacial skeleton. We provide a review of the clinical diagnosis of this syndrome and describe treatment options...
How airway venous malformations differ from airway infantile hemangiomasNooshin Parhizkar
DO, Division of Pediatric Otolaryngology, Seattle Children s Hospital, 4800 Sand Point Way NE, Mail Stop W 7729, Seattle, WA 98105 0371, USA
Arch Otolaryngol Head Neck Surg 137:352-7. 2011..To compare airway infantile hemangiomas (IHs) and venous malformations (VMs) clinically, radiographically, endoscopically, and histologically...
Gorham-stout syndrome of the petrous apex causing chronic cerebrospinal fluid leakSharon L Cushing
Division of Pediatric Otolaryngology Head and Neck Surgery, Seattle Children s Hospital, University of Washington, Seattle, Washington, USA
Otol Neurotol 31:789-92. 2010..To describe the clinical course, diagnostic features, and treatment of a case of Gorham-Stout syndrome involving the petrous apex and causing chronic cerebrospinal fluid (CSF) leak...
Multicenter interrater and intrarater reliability in the endoscopic evaluation of velopharyngeal insufficiencyKathleen C Y Sie
Division of Pediatric Otolaryngology, Childhood Communication Center, Children s Hospital and Regional Medical Center, PO Box 5371 6E 1, Seattle, WA 98105 0371, USA
Arch Otolaryngol Head Neck Surg 134:757-63. 2008..To explore interrater and intrarater reliability (R (inter) and R (intra), respectively) of a standardized scale applied to nasoendoscopic assessment of velopharyngeal (VP) function, across multiple centers...
Facial nerve anatomy, dissection and preservation in lymphatic malformation managementGi Soo Lee
Department of Otolaryngology Head and Neck Surgery, University of Washington, Seattle, WA, United States
Int J Pediatr Otorhinolaryngol 72:759-66. 2008..Data collected included: facial nerve function, relationship of lymphatic malformation to facial nerve, facial nerve anatomy, dissection extent and clinical outcome...
Hemangiomas of infancy: treatment of ulceration in the head and neckRoy F Thomas
Otolaryngology Service, Madigan Army Medical Center, Tacoma, Wash, USA
Arch Facial Plast Surg 7:312-5. 2005..We review the common characteristics of ulcerated hemangiomas and discuss the treatment modalities available. We present case reports to illustrate management options and a stepwise algorithm for treatment of ulcerated hemangiomas...
Head and neck endocrine surgery in children: 1997 and 2000Wayne J Harsha
Otolaryngology Service, Madigan Army Medical Center, Tacoma, USA
Arch Otolaryngol Head Neck Surg 131:564-70. 2005..Thyroglossal duct cyst excision and thyroid lobectomy are the most common procedures. There were regional differences in the rates of most HNE surgical treatments. In addition, hospital charges increased between 1997 and 2000...
