Andre Perisse

Summary

Affiliation: University of Maryland
Country: USA

Publications

  1. pmc An elaborated feeding cycle model for reductions in vectorial capacity of night-biting mosquitoes by insecticide-treated nets
    Arnaud Le Menach
    Universite Pierre et Marie Curie Paris 6, UMR S 707, Paris, France
    Malar J 6:10. 2007
  2. pmc Comparative effectiveness of nafcillin or cefazolin versus vancomycin in methicillin-susceptible Staphylococcus aureus bacteremia
    Marin L Schweizer
    Department of Epidemiology and Preventive Medicine, University of Maryland School of Medicine, Baltimore, MD, USA
    BMC Infect Dis 11:279. 2011
  3. pmc Impact of empiric antimicrobial therapy on outcomes in patients with Escherichia coli and Klebsiella pneumoniae bacteremia: a cohort study
    Kerri A Thom
    Department of Epidemiology and Preventive Medicine, University of Maryland School of Medicine, Baltimore, MD, USA
    BMC Infect Dis 8:116. 2008
  4. pmc Concurrent acute illness and comorbid conditions poorly predict antibiotic use in upper respiratory tract infections: a cross-sectional analysis
    Ilene H Zuckerman
    Department of Pharmaceutical Health Services Research, School of Pharmacy, University of Maryland, Baltimore, Baltimore, Maryland 21201, USA
    BMC Infect Dis 7:47. 2007
  5. pmc Genomic comparison of multi-drug resistant invasive and colonizing Acinetobacter baumannii isolated from diverse human body sites reveals genomic plasticity
    Jason W Sahl
    Department of Microbiology, Institute for Genome Sciences, Baltimore, MD 21201, USA
    BMC Genomics 12:291. 2011
  6. ncbi request reprint Impact of severity of illness bias and control group misclassification bias in case-control studies of antimicrobial-resistant organisms
    Anthony D Harris
    Department of Epidemiology and Preventive Medicine, University of Maryland, College Park, USA
    Infect Control Hosp Epidemiol 26:342-5. 2005
  7. ncbi request reprint A systematic review of quasi-experimental study designs in the fields of infection control and antibiotic resistance
    Anthony D Harris
    Division of Health Care Outcomes Research, Department of Epidemiology and Preventive Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    Clin Infect Dis 41:77-82. 2005
  8. ncbi request reprint What infection control interventions should be undertaken to control multidrug-resistant gram-negative bacteria?
    Anthony D Harris
    Department of Epidemiology and Preventive Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    Clin Infect Dis 43:S57-61. 2006
  9. pmc The use and interpretation of quasi-experimental studies in medical informatics
    Anthony D Harris
    Division of Healthcare Outcomes Research, Department of Epidemiology and Preventive Medicine, University of Maryland School of Medicine, 100 N Greene Street, Lower Level, Baltimore, MD, USA
    J Am Med Inform Assoc 13:16-23. 2006
  10. ncbi request reprint How important is patient-to-patient transmission in extended-spectrum beta-lactamase Escherichia coli acquisition
    Anthony D Harris
    Department of Epidemiology and Preventive Medicine, University of Maryland, 100 North Greene Street, Baltimore, MD 21201, USA
    Am J Infect Control 35:97-101. 2007

Detail Information

Publications74

  1. pmc An elaborated feeding cycle model for reductions in vectorial capacity of night-biting mosquitoes by insecticide-treated nets
    Arnaud Le Menach
    Universite Pierre et Marie Curie Paris 6, UMR S 707, Paris, France
    Malar J 6:10. 2007
    ..Insecticide Treated Nets (ITNs) are an important tool for malaria control. ITNs are effective because they work on several parts of the mosquito feeding cycle, including both adult killing and repelling effects...
  2. pmc Comparative effectiveness of nafcillin or cefazolin versus vancomycin in methicillin-susceptible Staphylococcus aureus bacteremia
    Marin L Schweizer
    Department of Epidemiology and Preventive Medicine, University of Maryland School of Medicine, Baltimore, MD, USA
    BMC Infect Dis 11:279. 2011
    ..The outcome of interest for this study was 30-day in-hospital mortality...
  3. pmc Impact of empiric antimicrobial therapy on outcomes in patients with Escherichia coli and Klebsiella pneumoniae bacteremia: a cohort study
    Kerri A Thom
    Department of Epidemiology and Preventive Medicine, University of Maryland School of Medicine, Baltimore, MD, USA
    BMC Infect Dis 8:116. 2008
    ....
  4. pmc Concurrent acute illness and comorbid conditions poorly predict antibiotic use in upper respiratory tract infections: a cross-sectional analysis
    Ilene H Zuckerman
    Department of Pharmaceutical Health Services Research, School of Pharmacy, University of Maryland, Baltimore, Baltimore, Maryland 21201, USA
    BMC Infect Dis 7:47. 2007
    ..Antibiotics are generally not indicated for upper respiratory infections (URIs). Our objectives were to describe patterns of URI treatment and to identify patient and provider factors associated with antibiotic use for URIs...
  5. pmc Genomic comparison of multi-drug resistant invasive and colonizing Acinetobacter baumannii isolated from diverse human body sites reveals genomic plasticity
    Jason W Sahl
    Department of Microbiology, Institute for Genome Sciences, Baltimore, MD 21201, USA
    BMC Genomics 12:291. 2011
    ..baumannii strains isolated from distinct body sites. Isolates from blood, peri-anal, and wound sources were examined in an attempt to identify genetic features that could be correlated to each isolation source...
  6. ncbi request reprint Impact of severity of illness bias and control group misclassification bias in case-control studies of antimicrobial-resistant organisms
    Anthony D Harris
    Department of Epidemiology and Preventive Medicine, University of Maryland, College Park, USA
    Infect Control Hosp Epidemiol 26:342-5. 2005
    ..If this bias exists, these studies might be expected to report lower odds ratios (ORs) because control-patients would be more like case-patients...
  7. ncbi request reprint A systematic review of quasi-experimental study designs in the fields of infection control and antibiotic resistance
    Anthony D Harris
    Division of Health Care Outcomes Research, Department of Epidemiology and Preventive Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    Clin Infect Dis 41:77-82. 2005
    ..Efforts to improve the conduct and presentation of quasi-experimental studies are urgently needed to more rigorously evaluate interventions...
  8. ncbi request reprint What infection control interventions should be undertaken to control multidrug-resistant gram-negative bacteria?
    Anthony D Harris
    Department of Epidemiology and Preventive Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    Clin Infect Dis 43:S57-61. 2006
    ....
  9. pmc The use and interpretation of quasi-experimental studies in medical informatics
    Anthony D Harris
    Division of Healthcare Outcomes Research, Department of Epidemiology and Preventive Medicine, University of Maryland School of Medicine, 100 N Greene Street, Lower Level, Baltimore, MD, USA
    J Am Med Inform Assoc 13:16-23. 2006
    ..They hope that future medical informatics studies will implement higher level quasi-experimental study designs that yield more convincing evidence for causal links between medical informatics interventions and outcomes...
  10. ncbi request reprint How important is patient-to-patient transmission in extended-spectrum beta-lactamase Escherichia coli acquisition
    Anthony D Harris
    Department of Epidemiology and Preventive Medicine, University of Maryland, 100 North Greene Street, Baltimore, MD 21201, USA
    Am J Infect Control 35:97-101. 2007
    ..The objective of this study was to quantify the amount of patient-to-patient transmission among patients who acquire an ESBL-producing E coli infection using perianal surveillance cultures in an intensive care unit (ICU) population...
  11. pmc Risk factors for colonization with extended-spectrum beta-lactamase-producing bacteria and intensive care unit admission
    Anthony D Harris
    Department of Epidemiology and Preventive Medicine, School of Medicine, University of Maryland, Baltimore 21201, USA
    Emerg Infect Dis 13:1144-9. 2007
    ..15; 95% CI 1.04-1.27). Coexisting conditions and previous antimicrobial drug exposure are thus predictive of colonization, and a large percentage of these patients have subsequent positive clinical cultures for ESBL-producing bacteria...
  12. ncbi request reprint Patient-to-patient transmission is important in extended-spectrum beta-lactamase-producing Klebsiella pneumoniae acquisition
    A D Harris
    Department of Epidemiology and Preventive Medicine, University of Maryland, Baltimore, MD 21201, USA
    Clin Infect Dis 45:1347-50. 2007
    ..Among 27 patients who acquired Klebsiella pneumoniae infection, 14 had infections (52%) that were due to patient-to-patient transmission, and 6 (22%) had a subsequent positive extended-spectrum beta-lactamase clinical culture results...
  13. pmc Targeted surveillance of methicillin-resistant Staphylococcus aureus and its potential use to guide empiric antibiotic therapy
    Anthony D Harris
    Department of Epidemiology and Preventive Medicine, University of Maryland School of Medicine, 685 W Baltimore St, Room 330, Baltimore, MD 21201, USA
    Antimicrob Agents Chemother 54:3143-8. 2010
    ..The risk of MRSA infection was far higher in those who were deemed to be at high risk and who were surveillance culture positive. Targeted MRSA active surveillance may be beneficial in guiding empiric anti-MRSA therapy...
  14. ncbi request reprint The use and interpretation of quasi-experimental studies in infectious diseases
    Anthony D Harris
    Department of Epidemiology and Preventive Medicine, University of Maryland, Baltimore, Maryland 21201, USA
    Clin Infect Dis 38:1586-91. 2004
    ....
  15. ncbi request reprint Control-group selection importance in studies of antimicrobial resistance: examples applied to Pseudomonas aeruginosa, Enterococci, and Escherichia coli
    Anthony D Harris
    Department of Epidemiology and Preventive Medicine, University of Maryland School of Medicine, and VA Maryland Health Care System, Baltimore, MD, USA
    Clin Infect Dis 34:1558-63. 2002
    ..68). The selection of control patients from the potentially suboptimal control type 1 can falsely identify certain antibiotics and overestimate the OR of the resistance-defining antibiotic...
  16. ncbi request reprint Methodological principles of case-control studies that analyzed risk factors for antibiotic resistance: a systematic review
    A D Harris
    Dept of Epidemiology and Preventive Medicine, University of Maryland Medical System, Baltimore, MD 21201, USA
    Clin Infect Dis 32:1055-61. 2001
    ..Future studies need to consider more closely the optimization of control group selection, adjusting for confounding caused by time at risk, and adjusting for confounding caused by comorbid illness...
  17. pmc Risk factors for piperacillin-tazobactam-resistant Pseudomonas aeruginosa among hospitalized patients
    Anthony D Harris
    Department of Epidemiology and Preventive Medicine, University of Maryland VA Maryland Health Care System, Baltimore, Maryland 21201, USA
    Antimicrob Agents Chemother 46:854-8. 2002
    ..aeruginosa. Our results suggest that the nosocomial isolation of piperacillin-tazobactam-resistant P. aeruginosa may be affected by multiple antibiotics...
  18. doi request reprint The importance of case-mix adjustment for infection rates and the need for more research
    Anthony D Harris
    Department of Epidemiology and Preventive Medicine, University of Maryland, Baltimore, Maryland 21201, USA
    Infect Control Hosp Epidemiol 29:693-4. 2008
  19. ncbi request reprint Risk factors for imipenem-resistant Pseudomonas aeruginosa among hospitalized patients
    Anthony D Harris
    Department of Epidemiology and Preventive Medicine, University of Maryland, VA Maryland Health Care System, 10 N Greene St BT111, Baltimore, MD 21201, USA
    Clin Infect Dis 34:340-5. 2002
    ..Antibiotics associated with ISPA are different from antibiotics associated with IRPA. The OR for imipenem as a risk factor for IRPA is less than that reported from studies in which control group selection was suboptimal...
  20. pmc Detection of methicillin-resistant Staphylococcus aureus and vancomycin-resistant enterococci on the gowns and gloves of healthcare workers
    Graham M Snyder
    Department of Epidemiology and Preventive Medicine, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA
    Infect Control Hosp Epidemiol 29:583-9. 2008
    ..To assess the rate of and the risk factors for the detection of methicillin-resistant S. aureus (MRSA) and vancomycin-resistant enterococci (VRE) on the protective gowns and gloves of healthcare workers (HCWs)...
  21. ncbi request reprint Impact of freezing on the future utility of archived surveillance culture specimens
    Heather P Green
    Department of Epidemiology and Preventive Medicine, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA
    Infect Control Hosp Epidemiol 28:886-8. 2007
    ..Results demonstrate that 98% of 250 bacterial isolates identified on initial culture were subsequently recovered by culture of frozen specimens after a median storage period of 564 days...
  22. ncbi request reprint The effect of active surveillance for vancomycin-resistant enterococci in high-risk units on vancomycin-resistant enterococci incidence hospital-wide
    Anwer H Siddiqui
    Division of Healthcare Outcomes Research, Department of Epidemiology and Preventive Medicine, University of Maryland School of Medicine, Baltimore 21201, USA
    Am J Infect Control 30:40-3. 2002
    ..The aim of this study was to describe the effect of active surveillance for patients with VRE in high-risk units on the VRE incidence rate hospital-wide...
  23. ncbi request reprint Co-carriage rates of vancomycin-resistant Enterococcus and extended-spectrum beta-lactamase-producing bacteria among a cohort of intensive care unit patients: implications for an active surveillance program
    Anthony D Harris
    Department of Epidemiology and Preventive Medicine, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA
    Infect Control Hosp Epidemiol 25:105-8. 2004
    ..To assess the co-colonization rates of extended-spectrum beta-lactamase (ESBL)-producing bacteria and vancomycin-resistant Enterococcus (VRE) obtained on active surveillance cultures...
  24. ncbi request reprint Rates of hand disinfection associated with glove use, patient isolation, and changes between exposure to various body sites
    Peter W Kim
    Department of Epidemiology and Preventive Medicine, University of Maryland School of Medicine, USA
    Am J Infect Control 31:97-103. 2003
    ..It is unclear whether workers change gloves and disinfect hands adequately between exposures to different body sites/secretions while caring for a patient...
  25. ncbi request reprint Aggressive control measures for resistant Acinetobacter baumannii and the impact on acquisition of methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococcus in a medical intensive care unit
    Marc Oliver Wright
    Infection Control Hospital Epidemiology, University of Maryland Medical Center, Baltimore, USA
    Infect Control Hosp Epidemiol 25:167-8. 2004
    ..Aggressive control measures can reduce VRE, and perhaps MRSA, transmission...
  26. pmc Impact of empiric antibiotic therapy on outcomes in patients with Pseudomonas aeruginosa bacteremia
    Regina B Osih
    University of Maryland, Department of Epidemiology and Preventive Medicine, 100 N Greene St lower level, Baltimore, MD 21201, USA
    Antimicrob Agents Chemother 51:839-44. 2007
    ..74). These data suggest that the use of appropriate empirical therapy, i.e., before susceptibility results are known may not be as critical to patient outcomes as other studies have suggested...
  27. pmc Do contact precautions cause depression? A two-year study at a tertiary care medical centre
    H R Day
    University of Maryland School of Medicine, Baltimore, MD, USA
    J Hosp Infect 79:103-7. 2011
    ..4, 95% confidence interval (CI) 1.2-1.5] but not with anxiety (OR 0.8, 95% CI 0.7-1.1) in the non-ICU population. Depression was 40% more prevalent among general inpatients on contact precautions...
  28. ncbi request reprint Assessing risks for a pre-emergent pathogen: virginiamycin use and the emergence of streptogramin resistance in Enterococcus faecium
    D L Smith
    Department of Epidemiology and Preventive Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    Lancet Infect Dis 3:241-9. 2003
    ..The potential effects are greatest for intermediate rates of human-to-human transmission (R0 approximately equal 1)...
  29. ncbi request reprint Preliminary assessment of an automated surveillance system for infection control
    Marc Oliver Wright
    Department of Infection Control and Hospital Epidemiology, University of Maryland Medical Center, 29 South Greene Street, Suite 400, Baltimore, MD 21201, USA
    Infect Control Hosp Epidemiol 25:325-32. 2004
    ..We examined the use of automated control charts, provided by an automated surveillance system, for detection of potential outbreaks...
  30. ncbi request reprint Risk of mortality with a bloodstream infection is higher in the less severely ill at admission
    Peter W Kim
    VA Maryland Health Care System, 100 N Greene St lower level, Baltimore, MD 21201, USA
    Am J Respir Crit Care Med 171:616-20. 2005
    ..Health care-associated bloodstream infections are common in critically ill patients; however, investigators have had difficulty in quantifying the clinical impact of these infections given the high expected mortality among these patients...
  31. pmc Bacterial contamination of health care workers' white coats
    Amy M Treakle
    Department of Medicine, University of Maryland Medical Center, Baltimore, MD, USA
    Am J Infect Control 37:101-5. 2009
    ....
  32. ncbi request reprint A survey on handwashing practices and opinions of healthcare workers
    A D Harris
    Beth Israel Deaconess Medical Center, Boston, MA, USA
    J Hosp Infect 45:318-21. 2000
    ..Healthcare workers are not in favour of interventions involving rewards and punishments, but are more attracted to interventions that make handwashing easier...
  33. pmc The role of patient-to-patient transmission in the acquisition of imipenem-resistant Pseudomonas aeruginosa colonization in the intensive care unit
    J Kristie Johnson
    Department of Pathology, Institute of Genomic Sciences, University of Maryland School of Medicine, 10 South Pine Street, Baltimore, MD 21201, USA
    J Infect Dis 200:900-5. 2009
    ..Imipenem-resistant Pseudomonas aeruginosa (IRPA) is an emerging problem. The causal role of antibiotic selective pressure versus patient-to-patient transmission has not been assessed using a large cohort...
  34. pmc Impact of a computerized clinical decision support system on reducing inappropriate antimicrobial use: a randomized controlled trial
    Jessina C McGregor
    Department of Epidemiology and Preventive Medicine, University of Maryland, Baltimore, 100 North Greene Street, Lower Level, Baltimore, MD 21201, USA
    J Am Med Inform Assoc 13:378-84. 2006
    ..However, most function with minimal computer support. We evaluated the effectiveness and cost-effectiveness of a computerized clinical decision support system for the management of antimicrobial utilization...
  35. pmc Controlling for severity of illness in outcome studies involving infectious diseases: impact of measurement at different time points
    Kerri A Thom
    Department of Epidemiology and Preventive Medicine, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA
    Infect Control Hosp Epidemiol 29:1048-53. 2008
    ..Severity of illness is an important confounder in outcome studies involving infectious diseases. However, it is unclear whether the time at which severity of illness is measured is important...
  36. pmc Low prevalence of Acinetobacter baumannii colonization on hospital admission
    Kerri A Thom
    Department of Epidemiology and Preventive Medicine, University of Maryland School of Medicine, 100 N Greene Street, Baltimore, MD 21201, USA
    Am J Infect Control 38:329-31. 2010
    ..18%); no multidrug-resistant A baumannii was identified. Interventions aimed at early identification of A baumannii-colonized patients may not benefit by widely targeting non-critically ill patients on hospital admission...
  37. pmc Multilocus sequence typing compared to pulsed-field gel electrophoresis for molecular typing of Pseudomonas aeruginosa
    Jennifer K Johnson
    Department of Pathology, University of Maryland School of Medicine, MSTF, Baltimore, MD 21201, USA
    J Clin Microbiol 45:3707-12. 2007
    ..999 versus 0.975, respectively). Thus, while MLST was better for detecting genetic relatedness, we determined that PFGE was more discriminatory than MLST for determining genetic differences in P. aeruginosa...
  38. pmc Clinical utility of infection control documentation of prior methicillin-resistant Staphylococcus aureus colonization or infection for optimization of empirical antibiotic therapy
    Marin L Schweizer
    Department of Epidemiology, University of Maryland School of Medicine, Baltimore, Maryland 2201, USA
    Infect Control Hosp Epidemiol 29:972-4. 2008
    ..Documented prior MRSA colonization or infection was predictive of subsequent MRSA infections (odds ratio, 4.05). Physicians appear to use this documentation when prescribing empirical therapy for suspected bacteremia...
  39. ncbi request reprint Increasing prevalence of gastrointestinal colonization with ceftazidime-resistant gram-negative bacteria among intensive care unit patients
    Kerri A Thom
    Department of Epidemiology and Preventive Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    Infect Control Hosp Epidemiol 28:1240-6. 2007
    ..Gastrointestinal colonization is an important reservoir for antibiotic-resistant bacteria, and it often precedes clinical infection...
  40. pmc Prevalence of methicillin-resistant Staphylococcus aureus and Acinetobacter baumannii in a long-term acute care facility
    Jon P Furuno
    Department of Epidemiology and Preventive Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    Am J Infect Control 36:468-71. 2008
    ..Patients in long-term acute care (LTAC) facilities often have many known risk factors for acquisition of antibiotic-resistant bacteria. However, the prevalence of resistance in these facilities has not been well described...
  41. pmc Animal antibiotic use has an early but important impact on the emergence of antibiotic resistance in human commensal bacteria
    David L Smith
    Department of Epidemiology and Preventive Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    Proc Natl Acad Sci U S A 99:6434-9. 2002
    ..Our model indicates that the greatest impact occurs very early in the emergence of resistance, when AR bacteria are rare, possibly below the detection limits of current surveillance methods...
  42. ncbi request reprint Summer Peaks in the Incidences of Gram-Negative Bacterial Infection Among Hospitalized Patients
    Eli N Perencevich
    Veterans Affairs Maryland Health Care System, and the Department of Epidemiology and Preventive Medicine, University of MarylandSchool of Medicine, Baltimore, Maryland 21202, USA
    Infect Control Hosp Epidemiol 29:1124-31. 2008
    ..We quantified the seasonal variation in the incidences of hospital infection caused by common bacterial pathogens and estimated the association between temperature changes and infection rates...
  43. ncbi request reprint Value of performing active surveillance cultures on intensive care unit discharge for detection of methicillin-resistant Staphylococcus aureus
    Jon P Furuno
    Department of Epidemiology and Preventive Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    Infect Control Hosp Epidemiol 28:666-70. 2007
    ..To quantify the value of performing active surveillance cultures for detection of methicillin-resistant Staphylococcus aureus (MRSA) on intensive care unit (ICU) discharge...
  44. ncbi request reprint Prediction rules to identify patients with methicillin-resistant Staphylococcus aureus and vancomycin-resistant enterococci upon hospital admission
    Jon P Furuno
    Department of Epidemiology and Preventive Medicine, University of Maryland School of Medicine, 100 N Greene Street, Baltimore, MD 21201, USA
    Am J Infect Control 32:436-40. 2004
    ..The aim of this study was to assess the validity of factors from past medical history in defining patients at high risk for subsequent positive cultures with VRE or MRSA upon hospital admission...
  45. pmc Frequent multidrug-resistant Acinetobacter baumannii contamination of gloves, gowns, and hands of healthcare workers
    Daniel J Morgan
    Departments of Epidemiology and Preventive Medicine, University of Maryland, Baltimore, Baltimore, MD 21201, USA
    Infect Control Hosp Epidemiol 31:716-21. 2010
    ..Multidrug-resistant (MDR) gram-negative bacilli are important nosocomial pathogens...
  46. pmc Predictive ability of positive clinical culture results and International Classification of Diseases, Ninth Revision, to identify and classify noninvasive Staphylococcus aureus infections: a validation study
    LaRee A Tracy
    Department of Epidemiology and Preventive Medicine, University of Maryland, Baltimore, Maryland, USA
    Infect Control Hosp Epidemiol 31:694-700. 2010
    ..To develop and validate an algorithm to identify and classify noninvasive infections due to Staphylococcus aureus by using positive clinical culture results and administrative data...
  47. ncbi request reprint Utility of the Chronic Disease Score and Charlson Comorbidity Index as comorbidity measures for use in epidemiologic studies of antibiotic-resistant organisms
    Jessina C McGregor
    Department of Epidemiology and Preventive Medicine, School of Medicine, University of Maryland, Baltimore, MD 21201, USA
    Am J Epidemiol 161:483-93. 2005
    ..05). A revised comorbidity measure specific to resistant infections would likely provide a better assessment of the comorbidity-attributable risk of antibiotic-resistant infections...
  48. pmc Multilocus sequence typing versus pulsed-field gel electrophoresis for characterization of extended-spectrum beta-lactamase-producing Escherichia coli isolates
    Lucia L Nemoy
    Department of Epidemiology and Preventive Medicine, University of Maryland School of Medicine, MSTF Building, Room 9 34, 10 South Pine Street, Baltimore, MD 21201, USA
    J Clin Microbiol 43:1776-81. 2005
    ..MLST has clear utility in studies of ESBL-producing E. coli, based on a greater discriminatory ability and reproducibility than PFGE and the ability to a priori define genetically related bacterial strains...
  49. pmc Epidemiological risk factors for isolation of ceftriaxone-resistant versus -susceptible citrobacter freundii in hospitalized patients
    Peter W Kim
    Department of Epidemiology and Preventive Medicine, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA
    Antimicrob Agents Chemother 47:2882-7. 2003
    ..1 to 6.2). Risk factors for CSCF were peripheral vascular disease (OR, 23.2; 95% CI, 4.3 to 124.6), AIDS (OR, 9.5; 95% CI, 1.6 to 55.5), cerebrovascular disease (OR, 4.2; 95% CI, 1.6 to 10.8), and ICU stay (OR, 3.1; 95% CI, 1.8 to 5.4)...
  50. ncbi request reprint Physicians' acceptable treatment failure rates in antibiotic therapy for coagulase-negative staphylococcal catheter-associated bacteremia: implications for reducing treatment duration
    Eli N Perencevich
    Veterans Affairs Maryland Healthcare System, Baltimore, MD 21201, USA
    Clin Infect Dis 41:1734-41. 2005
    ..We aimed to identify acceptable failure rates among infectious disease consultants (IDCs) for treatment of central venous catheter-associated bacteremia...
  51. pmc Methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococci co-colonization
    Jon P Furuno
    Department of Epidemiology and Preventive Medicine, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA
    Emerg Infect Dis 11:1539-44. 2005
    ..06, 95% CI 1.85-5.07). None of the co-colonized patients would have been identified with clinical cultures alone. We report a high prevalence of VRE/MRSA co-colonization upon admission to ICUs at a tertiary-care hospital...
  52. ncbi request reprint Identifying groups at high risk for carriage of antibiotic-resistant bacteria
    Jon P Furuno
    Department of Epidemiology and Preventive Medicine, University of Maryland School of Medicine, Baltimore 21201, USA
    Arch Intern Med 166:580-5. 2006
    ..We aimed to develop a highly sensitive, simple-to-administer prediction rule to identify subpopulations of patients at high risk for colonization on hospital admission...
  53. ncbi request reprint Comorbidity risk-adjustment measures were developed and validated for studies of antibiotic-resistant infections
    Jessina C McGregor
    Department of Epidemiology and Preventive Medicine, University of Maryland, Baltimore, MD 21201, USA
    J Clin Epidemiol 59:1266-73. 2006
    ....
  54. pmc Empiric antibiotic therapy for Staphylococcus aureus bacteremia may not reduce in-hospital mortality: a retrospective cohort study
    Marin L Schweizer
    Department of Epidemiology and Preventive Medicine, University of Maryland School of Medicine, Baltimore, Maryland, United States of America
    PLoS ONE 5:e11432. 2010
    ..We aimed to measure the clinical impact of appropriate empiric antibiotic therapy on mortality, while statistically adjusting for comorbidities, severity of illness and presence of virulence factors in the infecting strain...
  55. ncbi request reprint Acceptable rates of treatment failure in osteomyelitis involving the diabetic foot: a survey of infectious diseases consultants
    Eli N Perencevich
    VA Maryland Healthcare System, Dept of Epidemiology and Preventive Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    Clin Infect Dis 38:476-82. 2004
    ..4% to be acceptable. The methodology used in this study may prove useful in delineating acceptable treatment failure thresholds, an initial step in shortening durations of antimicrobial therapy...
  56. pmc Patients with Acinetobacter baumannii bloodstream infections are colonized in the gastrointestinal tract with identical strains
    Kerri A Thom
    Division of Healthcare Outcomes Research, Department of Epidemiology and Preventive Medicine, University of Maryland School of Medicine, 100 N Greene Street, Baltimore, MD 21201, USA
    Am J Infect Control 38:751-3. 2010
    ..Seven patients with imipenem-resistant A baumannii bacteremia were identified from January to June of 2008. Six of 7 (86%) patients were colonized in the gastrointestinal tract with genetically similar strains preceding their bacteremia...
  57. pmc Transfusion practice in the intensive care unit: a 10-year analysis
    Giora Netzer
    From the Division of Pulmonary and Critical Care Medicine, the Department of Epidemiology and Preventive Medicine, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA
    Transfusion 50:2125-34. 2010
    ..Clinical guidelines recommend a restrictive transfusion strategy in nonhemorrhaging critically ill patients...
  58. ncbi request reprint Projected benefits of active surveillance for vancomycin-resistant enterococci in intensive care units
    Eli N Perencevich
    Veterans Affairs Maryland Healthcare System, Baltimore, Maryland, USA
    Clin Infect Dis 38:1108-15. 2004
    ..Passive surveillance was minimally effective. Using the best available data, active surveillance is projected to be effective for reducing VRE transmission in ICU settings...
  59. ncbi request reprint Statistical analysis and application of quasi experiments to antimicrobial resistance intervention studies
    Michelle Shardell
    Department of Epidemiology and Preventive Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    Clin Infect Dis 45:901-7. 2007
    ..An example of a hospital-based intervention to reduce methicillin-resistant Staphylococcus aureus infection rates and reduce overall length of stay is used to explore these methods...
  60. pmc Comparison of culture media for detection of Acinetobacter baumannii in surveillance cultures of critically-ill patients
    A O Ajao
    Department of Epidemiology and Public Health, University of Maryland School of Medicine, 685 W Baltimore St, Baltimore, MD 21201, USA
    Eur J Clin Microbiol Infect Dis 30:1425-30. 2011
    ..baumannii. CHROMagar did not differentiate MDR- A. baumannii from non-MDR-A. baumannii. CHROMagar may be useful for rapid detection of patients with MDR-A. baumannii if improved upon to better select for MDR-A. baumannii...
  61. pmc Fluoroquinolone use and Clostridium difficile-associated diarrhea
    Margaret E McCusker
    University of Maryland, Baltimore, Maryland, USA
    Emerg Infect Dis 9:730-3. 2003
    ..A multivariable regression model showed that treatment with fluoroquinolones (odds ratio 12.7; 95% confidence interval 2.6 to 61.6) was the strongest risk factor for CDAD...
  62. ncbi request reprint Relative influence of antibiotic therapy attributes on physician choice in treating acute uncomplicated pyelonephritis
    Jessina C McGregor
    Department of Epidemiology and Preventive Medicine, University of Maryland, Baltimore, USA
    Med Decis Making 27:387-94. 2007
    ....
  63. pmc Efficient recovery of fluoroquinolone-susceptible and fluoroquinolone-resistant Escherichia coli strains from frozen samples
    Ebbing Lautenbach
    Division of Infectious Diseases of the Department of Medicine, the Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104 6021, USA
    Infect Control Hosp Epidemiol 29:367-9. 2008
    ..The strains that were not recovered were typically present only in low numbers in the initial sample. These findings emphasize the utility of frozen surveillance samples...
  64. ncbi request reprint The case-case-control study design: addressing the limitations of risk factor studies for antimicrobial resistance
    Keith S Kaye
    Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA
    Infect Control Hosp Epidemiol 26:346-51. 2005
    ..There are significant limitations of the standard case-control study design for identifying risk factors for resistant organisms. The objective of this study was to develop a study design to overcome these limitations...
  65. pmc Persistent colonization and the spread of antibiotic resistance in nosocomial pathogens: resistance is a regional problem
    David L Smith
    Fogarty International Center, National Institutes of Health, Bethesda, MD 20892 2220, USA
    Proc Natl Acad Sci U S A 101:3709-14. 2004
    ..To successfully manage ARB at tertiary-care hospitals, regional coordination of infection control may be necessary, including tracking asymptomatic carriers through health-care systems...
  66. pmc Multidrug-resistant Acinetobacter infection mortality rate and length of hospitalization
    Rebecca H Sunenshine
    Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    Emerg Infect Dis 13:97-103. 2007
    ..5, 95% CI 1.2-5.4 and OR 4.2, 95% CI 1.5-11.6] respectively). Increased hospitalization associated with MDR Acinetobacter infection emphasizes the need for infection control strategies to prevent cross-transmission in healthcare settings...
  67. ncbi request reprint Methicillin-resistant Staphylococcus aureus infection and colonization among hospitalized prisoners
    Marc Oliver Wright
    Evanston Northwestern Healthcare, Department of Infection Control, Evanston, IL 60201, USA
    Infect Control Hosp Epidemiol 28:877-9. 2007
    ..Hospitalized prisoners are at high risk for MRSA infection and colonization, and surveillance should include cultures of nares and wound samples...
  68. ncbi request reprint A systematic review of the methods used to assess the association between appropriate antibiotic therapy and mortality in bacteremic patients
    Jessina C McGregor
    Oregon State University College of Pharmacy, Portland, OR 97239, USA
    Clin Infect Dis 45:329-37. 2007
    ..In brief, future studies should define "inappropriate" therapy on the basis of in vitro susceptibility data, should separately evaluate empiric and definitive therapy, and should control for the baseline severity of illness...
  69. doi request reprint Measuring acceptable treatment failure rates for community-acquired pneumonia: potential for reducing duration of treatment and antimicrobial resistance
    Keith S Kaye
    Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA
    Infect Control Hosp Epidemiol 29:137-42. 2008
    ..Reducing the duration of antibiotic therapy is one strategy for reducing antibiotic exposure and thereby minimizing the potential for the emergence of antimicrobial resistance...
  70. ncbi request reprint How important is the environment in the emergence of nosocomial antimicrobial-resistant bacteria?
    Anthony D Harris
    Clin Infect Dis 46:686-8. 2008
  71. pmc Test characteristics of perirectal and rectal swab compared to stool sample for detection of fluoroquinolone-resistant Escherichia coli in the gastrointestinal tract
    Ebbing Lautenbach
    Division of Infectious Diseases, Department of Biostatistics and Epidemiology, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, PA 19104 6021, USA
    Antimicrob Agents Chemother 49:798-800. 2005
    ..For rectal swab, the sensitivity was 90% (95% CI, 68 to 99%) and the specificity was 100% (95% CI, 91 to 100%)...
  72. ncbi request reprint Willingness to pay to avoid sharps-related injuries: a study in injured health care workers
    David N Fisman
    City of Hamilton Social and Public Health Services Department, Ontario, Canada
    Am J Infect Control 30:283-7. 2002
    ..Injuries caused by sharp medical devices are common among health care workers and may result in the transmission of human immunodeficiency virus and hepatitis C virus...
  73. ncbi request reprint Fatigue increases the risk of injury from sharp devices in medical trainees: results from a case-crossover study
    David N Fisman
    Drexel University School of Public Health, Philadelphia, PA, 19102, USA
    Infect Control Hosp Epidemiol 28:10-7. 2007
    ..Our objective was to evaluate the relationship between fatigue and workplace injury risk among medical trainees and nontrainee healthcare workers...
  74. ncbi request reprint Sharps-related injuries in health care workers: a case-crossover study
    David N Fisman
    Hamilton Department of Social and Public Health Services, McMaster University, Hamilton, Ontario, Canada
    Am J Med 114:688-94. 2003

Research Grants9

  1. Study design importance in analyzing emerging pathogens
    Anthony Harris; Fiscal Year: 2005
    ..The second aim will be done by combining epidemiological relatedness and molecular relatedness through pulse-field gel electrophoresis of ESBL cultures to quantify the importance of patient to patient transmission. ..
  2. Epidemiology of imipenem-resistant P.aeruginosa
    Anthony Harris; Fiscal Year: 2007
    ..Aim 4: Determine the cost-effectiveness of three different infection control interventions. ..
  3. New Nosocomial Interventions to Decrease Antimicrobial Resistance Transmission
    Anthony Harris; Fiscal Year: 2007
    ....
  4. Epidemiology of emerging pathogens among hospitalizeds patients
    Anthony D Harris; Fiscal Year: 2010
    ..The reasons for the emergence of A. baumannii are unknown and no interventions have been successful at curbing this emergence. For these reasons, A. baumannii is a significant public health problem. ..