Subashan Perera

..To estimate the magnitude of small meaningful and substantial individual change in physical performance measures and evaluate their responsiveness...

..To describe the management of and satisfaction with laboratory testing, and desirability of laboratory health information technology in the nursing home setting...

..Currently, there is limited information on nonpain symptoms and their appropriate treatment in this setting at the end of life...

..Design A cross-sectional secondary analysis of observational cohort data was conducted...

..A task-oriented, motor sequence learning exercise intervention has been shown to reduce the energy cost of walking and improve gait speed, but whether the intervention also improves activity and participation has not been demonstrated...

..Tests of walking during challenging conditions may uncover mobility difficulty that is not identified with usual gait testing...

..Physical performance measures, such as gait speed, might help account for variability, allowing clinicians to make more individualized estimates...

..Heel QUS is associated with DXA-derived BMD at other major axial sites and may be used to follow skeletal health and bone mass changes in these women...

..To examine screening strategies for osteoporosis and fractures for treatment of long-term care residents...

..To examine the test-retest reliability and concurrent validity of variability of gait characteristics...

..This study estimated clinically meaningful change in measures of gait variability using both distribution- and anchor-based approaches...

..To assess whether the Timed Up and Go (TUG) is superior to gait speed in predicting multiple geriatric outcomes...

..Abnormalities of gait and changes in posture during walking are more common in older adults than in young adults and may contribute to an increase in the energy expended for walking...

..To develop a consensus list of agreed-upon laboratory, pharmacy, and Minimum Data Set signals that a computer system can use in the nursing home to detect potential adverse drug reactions (ADRs)...

..Most video games do not involve physical exercise, but some novel forms of interactive video games combine physical activity and cognitive challenge...

..The purpose was to examine the effect of age and fear of falling on gait during transition to a narrow path...

..Our objective was to examine changes in bone density and turnover with sustained, discontinued, or delayed oral bisphosphonate therapy in men receiving ADT...

..Because walking may also be energy inefficient in people with decreased mobility, another approach is to reduce energy cost by improving timing and coordination (TC) of movement...

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..In addition to bone mineral density (BMD), trabecular microstructure contributes to skeletal strength. Our goal was to examine changes in trabecular microstructure in women on therapy...

..DXA alone leads to misclassifications of osteoporosis, which can be avoided by VF assessment. HR-MRI provides a novel technique to assess deterioration of structural integrity in men with VF and adds micro-structural information...

..To determine whether fear avoidance beliefs (FABs) in older adults with chronic low back pain (CLBP) are significantly associated with gait speed decline and/or self-report of greater disability...

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..To estimate the relationship between 1-year improvement in measures of health and physical function and 8-year survival...

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..Depression in older adults is often undertreated due, in part, to medication costs. We examined the impact of improved prescription drug coverage under Medicare Part D on use of antidepressants, medication choice, and adherence...

..To obtain normative longitudinal vestibulo-ocular and balance test data in children from ages three to nine years with normal middle ear status...

..GCAE was more effective than PENS alone in reducing fear avoidance beliefs, but not in reducing pain or in improving physical function...

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..Specific patterns of gait variability may imply different underlying causes. Types of gait variability should be specified. Interventions may be targeted at specific types of gait variability...

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..To expand the ability to assess physical frailty by developing a Clinical Global Impression of Change in Physical Frailty (CGIC-PF) instrument...

..g., internal medicine, family medicine, geriatric medicine) should pay more systematic attention to educating trainees about chronic pain to optimize patient care, decrease suffering, and diminish healthcare expenditures...

..To assess the ability of gait speed alone and a three-item lower extremity performance battery to predict 12-month rates of hospitalization, decline in health, and decline in function in primary care settings serving older adults...

..We examined treatment effects on these outcomes in a randomized controlled trial (RCT) of exercise in subacute stroke survivors...

..These results suggest that deficits in inhibitory function may detrimentally affect step decision processing, by delaying voluntary step responses...

..Replication is needed in a population with more thorough ascertainment of PD onset...

..Improving immunization rates across multiple LTC facilities remains an elusive challenge. This quality improvement study sought to improve immunization rates across 6 LTC facilities and identify persistent barriers to better performance...

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..To examine the prevalence and correlates of non-opioid and opioid analgesic use and descriptively evaluate potential undertreatment in a sample of community-dwelling elders with symptomatic knee and/or hip osteoarthritis (OA)...

..Gait speed is a strong predictor of incident walking disability. The objective was to determine if gait variability adds to the prediction of incident mobility disability independent of gait speed...

..Patient-related characteristics and beliefs have not been the focus of prior research in this area, which has primarily evaluated the effects of patients' health status and health care system factors...

..To investigate the influence of androgen deprivation therapy (ADT) in men with nonmetastatic prostate cancer...

..Striatal dopaminergic activity decreases with normal aging...

..The objective of this study was to conduct a systematic review of pharmacy and laboratory signals used by clinical event monitors to detect ADEs in hospitalized adults...

..The nematode Caenorhabditis elegans might be a novel animal model for sarcopenia as worms experience sarcopenia during aging and mutations affecting the daf-2/insulin-like signaling pathway are able to delay this process...

..To have health care professionals in nursing homes identify organizational-level and individual-level modifiable barriers to medication error reporting...

..We explored perceived advantages and disadvantages of video dance as a personal exercise option in postmenopausal women...

..Limited data are available on the efficacy of oral bisphosphonate therapy in breast cancer survivors. Our goal was to examine prevention of breast cancer-related bone loss in this cohort...

..We examined the impact of improvements in drug coverage under Medicare Part D on utilization of, and adherence to, medications for heart failure in older adults...

..The purpose of this study was to examine the construct validity of the Stroke Impact Scale (SIS) using telephone mode of administration...

..The purpose of this study was to examine if the amelioration of stroke-related neuromuscular impairments, improved cardiovascular fitness, or better balance contributed to gains in distance walking...

..The purpose of this study was to examine the interaction of religion and spirituality with self-reported health status in a community-dwelling geriatric population...

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..To examine racial/ethnic variations in rates of hospice use in a national cohort and to identify individual characteristics associated with hospice use...

..Potentially inappropriate medication use is a serious quality concern, especially when it occurs in more vulnerable older adults or for extended durations...

..This study evaluated assessments of physical functioning and social functioning using the Stroke Impact Scale (SIS) and Short Form-36 (SF-36) to characterize health-related quality of life for patients after stroke...

..Further studies are needed to determine if rehabilitation poststroke can increase the rate of knee strength development and if it results in faster walking speeds...

..The purposes of this study were to compare proxy-patient responses on each domain of the Stroke Impact Scale (SIS) and the SIS-16, estimate the bias, and evaluate the validity of proxy scores...

..8 m/s). The purpose of the current study was to determine whether changes in velocity-based community ambulation classification were related to clinically meaningful changes in stroke-related function and quality of life...

..These stroke survivors have severely limited functional exercise capacity. Research and clinical practice in stroke rehabilitation should incorporate more comprehensive evaluation and treatment of endurance limitations...

..05 for all comparisons). The results point to a need for more PCP education about CLBP in older adults. It also suggests that accurate needs assessment should not rely on physician confidence ratings alone...

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..Frail elderly (FE) adults who are nursing home eligible but are receiving home- and community-based services (HCBS) constitute a distinct group sharing a high disease burden and high levels of medication use with the NF population...

..The objective of this study was to determine whether a structured, progressive, physiologically based exercise program for subacute stroke produces gains greater than those attributable to spontaneous recovery and usual care...

..The purpose of this study was to examine response rate, mode effects, and reliability of the Stroke Impact Scale (SIS) in a veteran stroke population using mail and telephone modes of administration...

..The purpose of this study was to compare disability and quality of life as measured by the Stroke Impact Scale (SIS) of stroke patients deemed recovered (Barthel Index > or =95) with 2 stroke-free populations of community-dwelling elderly...

..Determine whether a rehabilitation program targeting functional motor recovery of persons with poststroke hemiparesis improved motor coordination...

..To examine the effect of exercise on depressive symptoms and the effect of baseline depressive symptoms on the benefits from exercise in stroke survivors who have completed acute rehabilitation...

..Transient declines in gait speed and self-reported health are as common as persistent declines and affect mortality risk...

..These results warrant further investigation of altered sensorimotor processing or compensatory biomechanical strategies that may lead to inaccurate grip force execution after strokes...

..Neuromuscular impairments poststroke contribute to diminished performance in the 6-minute walk test. Pulse and blood pressure pre- and posttesting can indicate cardiovascular stress...

..Both newer and older antidepressants were used at modestly higher rates in urban areas. Further work is needed to elucidate the patient, prescriber, and facility factors that explain these prescribing patterns...