Alexander V Pereboev

Summary

Affiliation: University of Alabama at Birmingham
Country: USA

Publications

  1. ncbi request reprint Enhanced gene transfer to mouse dendritic cells using adenoviral vectors coated with a novel adapter molecule
    Alexander V Pereboev
    Division of Human Gene Therapy, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    Mol Ther 9:712-20. 2004
  2. pmc Genetically delivered antibody protects against West Nile virus
    Alexander Pereboev
    Division of Human Gene Therapy, Department of Medicine, University of Alabama at Birmingham 35294 2172, USA
    Antiviral Res 77:6-13. 2008
  3. ncbi request reprint Rhesus monocyte-derived dendritic cells modified to over-express TGF-beta1 exhibit potent veto activity
    Clement Asiedu
    Department of Surgery, Division of Transplant Immunology, University of Alabama at Birmingham, 35294, USA
    Transplantation 74:629-37. 2002
  4. ncbi request reprint Converting nonhuman primate dendritic cells into potent antigen-specific cellular immunosuppressants by genetic modification
    Asiedu Clement
    Department of Surgery, University of Alabama at Birmingham, 35294, USA
    Immunol Res 26:297-302. 2002
  5. ncbi request reprint Adenovirus serotype 3 utilizes CD80 (B7.1) and CD86 (B7.2) as cellular attachment receptors
    Joshua J Short
    Department of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294 2172, USA
    Virology 322:349-59. 2004
  6. ncbi request reprint The natural history of a novel, systemic, disseminated model of syngeneic mouse B-cell lymphoma
    Michael J Passineau
    Department of Medicine, University of Alabama at Birmingham, AL 35291, USA
    Leuk Lymphoma 46:1627-1638. 2005
  7. pmc Chimeric adenoviral vectors incorporating a fiber of human adenovirus 3 efficiently mediate gene transfer into prostate cancer cells
    Miho Murakami
    Division of Human Gene Therapy, Department of Medicine, Obstetrics and Gynecology, Pathology, Surgery, The University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
    Prostate 70:362-76. 2010
  8. ncbi request reprint CD40 is expressed on ovarian cancer cells and can be utilized for targeting adenoviruses
    Tanja Hakkarainen
    Department of Biotechnology and Molecular Medicine, A I Virtanen Institute for Molecular Sciences, University of Kuopio, 70211 Kuopio, Finland
    Clin Cancer Res 9:619-24. 2003

Research Grants

  1. Recombinant antibodies as an anti-microbial shield
    Alexander Pereboev; Fiscal Year: 2004

Collaborators

Detail Information

Publications8

  1. ncbi request reprint Enhanced gene transfer to mouse dendritic cells using adenoviral vectors coated with a novel adapter molecule
    Alexander V Pereboev
    Division of Human Gene Therapy, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    Mol Ther 9:712-20. 2004
    ....
  2. pmc Genetically delivered antibody protects against West Nile virus
    Alexander Pereboev
    Division of Human Gene Therapy, Department of Medicine, University of Alabama at Birmingham 35294 2172, USA
    Antiviral Res 77:6-13. 2008
    ..Adenovirus-mediated in vivo delivery of the antibody gene resulted in sustained Fc-9E2 serum levels leading to abrogation of lethal WNV infection in an animal model...
  3. ncbi request reprint Rhesus monocyte-derived dendritic cells modified to over-express TGF-beta1 exhibit potent veto activity
    Clement Asiedu
    Department of Surgery, Division of Transplant Immunology, University of Alabama at Birmingham, 35294, USA
    Transplantation 74:629-37. 2002
    ..Accordingly, we examined a hypothesis that mature rhesus monkey (Rh) monocyte-derived dendritic cells (MDDCs) modified by gene transfer to over-express active TGF-beta1 might mediate veto activity without the need to express CD8alpha...
  4. ncbi request reprint Converting nonhuman primate dendritic cells into potent antigen-specific cellular immunosuppressants by genetic modification
    Asiedu Clement
    Department of Surgery, University of Alabama at Birmingham, 35294, USA
    Immunol Res 26:297-302. 2002
    ..Such modified MDDCs have the potential to promote tolerance induction to allografts in vivo...
  5. ncbi request reprint Adenovirus serotype 3 utilizes CD80 (B7.1) and CD86 (B7.2) as cellular attachment receptors
    Joshua J Short
    Department of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294 2172, USA
    Virology 322:349-59. 2004
    ..This finding suggests a mechanism whereby viral exploitation of these proteins as receptors may achieve both goals of cellular entry and evading the immune system...
  6. ncbi request reprint The natural history of a novel, systemic, disseminated model of syngeneic mouse B-cell lymphoma
    Michael J Passineau
    Department of Medicine, University of Alabama at Birmingham, AL 35291, USA
    Leuk Lymphoma 46:1627-1638. 2005
    ..The present study therefore describes a high-fidelity model of disseminated lymphoma with implications for novel targeted therapeutics...
  7. pmc Chimeric adenoviral vectors incorporating a fiber of human adenovirus 3 efficiently mediate gene transfer into prostate cancer cells
    Miho Murakami
    Division of Human Gene Therapy, Department of Medicine, Obstetrics and Gynecology, Pathology, Surgery, The University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
    Prostate 70:362-76. 2010
    ..We evaluated whether Ad vectors displaying species B fiber shaft and knob domains (Ad5F3Luc1, Ad5F11Luc1, and Ad5F35Luc1) would efficiently infect cancer cells of distinct origins, including prostate cancer...
  8. ncbi request reprint CD40 is expressed on ovarian cancer cells and can be utilized for targeting adenoviruses
    Tanja Hakkarainen
    Department of Biotechnology and Molecular Medicine, A I Virtanen Institute for Molecular Sciences, University of Kuopio, 70211 Kuopio, Finland
    Clin Cancer Res 9:619-24. 2003
    ..In this study, we demonstrate the expression of CD40 on several ovarian carcinoma cell lines and the ability of CD40 to mediate targeted adenoviral infection in vitro...

Research Grants1

  1. Recombinant antibodies as an anti-microbial shield
    Alexander Pereboev; Fiscal Year: 2004
    ..To test the concept of a gene-therapy approach of the recAb anti-microbial defense in animal model. ..