A K Percy

Summary

Affiliation: University of Alabama at Birmingham
Country: USA

Publications

  1. pmc Profiling scoliosis in Rett syndrome
    Alan K Percy
    Department of Pediatrics, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
    Pediatr Res 67:435-9. 2010
  2. pmc Variable phenotypic expression of a MECP2 mutation in a family
    Kimberly Augenstein
    Neuromuscular and Rehabilitation Associates of Northern Michigan, Traverse City, MI, USA
    J Neurodev Disord 1:313. 2009
  3. ncbi request reprint Rett syndrome: recent research progress
    Alan K Percy
    Department of Pediatrics, University of Alabama at Birmingham, AL 35294 0021, USA
    J Child Neurol 23:543-9. 2008
  4. doi request reprint Rett syndrome: North American database
    Alan K Percy
    Civitan International Research Center, University of Alabama at Birmingham, 35294 0021, USA
    J Child Neurol 22:1338-41. 2007
  5. ncbi request reprint Rett syndrome: clinical and molecular update
    Alan K Percy
    Department of Pediatrics, University of Alabama at Birmingham, Birmingham, Alabama, USA
    Curr Opin Pediatr 16:670-7. 2004
  6. ncbi request reprint Child neurology training via the research pathway: outcome study
    Alan K Percy
    Department of Pediatrics, University of Alabama at Birmingham, Birmingham, AL 35233 1711, USA
    J Child Neurol 19:142-4. 2004
  7. ncbi request reprint Rett syndrome: model of neurodevelopmental disorders
    Alan K Percy
    Civitan International Research Center, University of Alabama, Birmingham, AL 35294, USA
    J Child Neurol 20:718-21. 2005
  8. pmc Rett syndrome diagnostic criteria: lessons from the Natural History Study
    Alan K Percy
    Department of Pediatric Neurology and Civitan International Research Center, University of Alabama at Birmingham, Birmingham, AL, USA
    Ann Neurol 68:951-5. 2010
  9. pmc Rett syndrome: exploring the autism link
    Alan K Percy
    Civitan International Research Center, University of Alabama at Birmingham, 35294, USA
    Arch Neurol 68:985-9. 2011
  10. ncbi request reprint Paul Dyken Lecture of the Southern Pediatric Neurology Society. Inherited neurodegenerative disease: the evolution of our thinking
    A K Percy
    Department of Pediatrics, University of Alabama at Birmingham, USA
    J Child Neurol 14:256-62. 1999

Collaborators

Detail Information

Publications30

  1. pmc Profiling scoliosis in Rett syndrome
    Alan K Percy
    Department of Pediatrics, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
    Pediatr Res 67:435-9. 2010
    ..Clinical trial design should account for scoliosis and related factors judiciously...
  2. pmc Variable phenotypic expression of a MECP2 mutation in a family
    Kimberly Augenstein
    Neuromuscular and Rehabilitation Associates of Northern Michigan, Traverse City, MI, USA
    J Neurodev Disord 1:313. 2009
    ..Strategies for accurate diagnosis in such instances should be considered carefully...
  3. ncbi request reprint Rett syndrome: recent research progress
    Alan K Percy
    Department of Pediatrics, University of Alabama at Birmingham, AL 35294 0021, USA
    J Child Neurol 23:543-9. 2008
    ..As such, it is timely to update recent research progress. This update summarizes research advances during the past 18 to 24 months in terms of clinical and translational research, as well as basic research...
  4. doi request reprint Rett syndrome: North American database
    Alan K Percy
    Civitan International Research Center, University of Alabama at Birmingham, 35294 0021, USA
    J Child Neurol 22:1338-41. 2007
    ....
  5. ncbi request reprint Rett syndrome: clinical and molecular update
    Alan K Percy
    Department of Pediatrics, University of Alabama at Birmingham, Birmingham, Alabama, USA
    Curr Opin Pediatr 16:670-7. 2004
    ..Recent reports not only present new insights into the clinical and molecular understanding of this unique disorder but also have important implications for the neurobiology beyond Rett syndrome...
  6. ncbi request reprint Child neurology training via the research pathway: outcome study
    Alan K Percy
    Department of Pediatrics, University of Alabama at Birmingham, Birmingham, AL 35233 1711, USA
    J Child Neurol 19:142-4. 2004
    ..Thus far, these trainees have published more than 125 articles in peer-reviewed journals. Although small in scope, this training track has met its objective of producing clinician-scientists...
  7. ncbi request reprint Rett syndrome: model of neurodevelopmental disorders
    Alan K Percy
    Civitan International Research Center, University of Alabama, Birmingham, AL 35294, USA
    J Child Neurol 20:718-21. 2005
    ....
  8. pmc Rett syndrome diagnostic criteria: lessons from the Natural History Study
    Alan K Percy
    Department of Pediatric Neurology and Civitan International Research Center, University of Alabama at Birmingham, Birmingham, AL, USA
    Ann Neurol 68:951-5. 2010
    ..This analysis underscores the critical role of main criteria for classic RTT; variant RTT requires both main and supportive criteria...
  9. pmc Rett syndrome: exploring the autism link
    Alan K Percy
    Civitan International Research Center, University of Alabama at Birmingham, 35294, USA
    Arch Neurol 68:985-9. 2011
    ..Fundamental understanding of autism based on unique genetic mechanism(s) must await similar advances...
  10. ncbi request reprint Paul Dyken Lecture of the Southern Pediatric Neurology Society. Inherited neurodegenerative disease: the evolution of our thinking
    A K Percy
    Department of Pediatrics, University of Alabama at Birmingham, USA
    J Child Neurol 14:256-62. 1999
    ..These issues include a high index of suspicion for an inherited neurometabolic disease and an open mind to possible interrelations with other known and seemingly dissimilar conditions...
  11. ncbi request reprint Genetics of Rett syndrome: properties of the newly discovered gene and pathobiology of the disorder
    A K Percy
    Department of Pediatrics, University of Alabama at Birmingham, School of Medicine, 35233 1711, USA
    Curr Opin Pediatr 12:589-95. 2000
    ..As such, this discovery opens up completely new vistas as to fundamental neurobiologic processes, to disease mechanisms in the neurodevelopmental disabilities, and to potential new therapeutic strategies for RS and related disorders...
  12. ncbi request reprint Neuropathology of occipital horn syndrome
    C A Palmer
    Department of Neurology, University of Alabama at Birmingham, 35294, USA
    J Child Neurol 16:764-6. 2001
    ..These findings are similar to those seen in the brains of patients with Menkes' syndrome, which is not surprising, given the known phenotypic overlap and the proven allelism of occipital horn syndrome with classic Menkes' syndrome...
  13. ncbi request reprint Cocaine inhibition of neuronal differentiation in NGF-induced PC12 cells is independent of ras signaling
    D A Zachor
    Department of Pediatrics, University of Alabama at Birmingham, UAB, Civitan International Research Center, 35294 0017, USA
    Int J Dev Neurosci 18:765-72. 2000
    ..These results suggest that cocaine, dopamine and activation of D1 receptors affect the NGF signaling downstream, independent of ras expression, leading to altered neuronal differentiation...
  14. ncbi request reprint Cocaine inhibits NGF-induced PC12 cells differentiation through D(1)-type dopamine receptors
    D A Zachor
    Department of Pediatrics, University of Alabama at Birmingham, 331C, Sparks Building, 1720 Seventh Avenue South, Birmingham, AL 35294 0017, USA
    Brain Res 869:85-97. 2000
    ..Subsequently, up regulation of D(1) receptors alters NGF signaling pathways...
  15. ncbi request reprint Deep sedation with propofol in patients with Rett syndrome
    Nancy M Tofil
    Department of Pediatrics, Division of Critical Care, University of Alabama, Birmingham, AL 35233, USA
    J Child Neurol 21:857-60. 2006
    ..Sedation of patients with Rett syndrome is associated with a relatively high rate of complications and should not be done without appropriate personnel available who recognize the risks of sedating this unique population...
  16. ncbi request reprint Deep sedation with propofol in patients with Rett syndrome
    Nancy M Tofil
    Department of Pediatrics, Division of Critical Care, University of Alabama at Birmingham, Birmingham, AL, USA
    J Child Neurol 21:210-3. 2006
    ..Sedation of patients with Rett syndrome is associated with a relatively high rate of complications and should not be done without appropriate personnel available who recognize the risks of sedating this unique population...
  17. ncbi request reprint Rett syndrome. Current status and new vistas
    Alan K Percy
    Departments of Pediatrics, Neurology, and Neurobiology, University of Alabama, Birmingham School of Medicine, 1600 7th Avenue South, Suite 516, Birmingham, AL 35233, USA
    Neurol Clin 20:1125-41. 2002
    ..These rapid advances in our understanding of RS over the past three decades have opened new avenues of study in developmental neurobiology...
  18. ncbi request reprint Clinical trials and treatment prospects
    Alan K Percy
    University of Alabama at Birmingham, School of Medicine, Birmingham, Alabama 35233, USA
    Ment Retard Dev Disabil Res Rev 8:106-11. 2002
    ..The availability of animal models expressing mutations in MECP2 should enhance the evaluation of innovative therapies for RS...
  19. pmc Clinical severity and quality of life in children and adolescents with Rett syndrome
    J B Lane
    University of Alabama, Birmingham, AL, USA
    Neurology 77:1812-8. 2011
    ..This study describes the impact of clinical severity on QOL among female children and adolescents with classic RTT...
  20. ncbi request reprint Early progressive encephalopathy in boys and MECP2 mutations
    P Kankirawatana
    Department of Pediatrics, University of Alabama at Birmingham, USA
    Neurology 67:164-6. 2006
    ..MECP2 mutations should be assessed in boys with progressive encephalopathy and one or more of respiratory insufficiency, abnormal movements or tone, and intractable seizures...
  21. ncbi request reprint C-fos mediates cocaine inhibition of NGF-induced PC12 cell differentiation
    D A Zachor
    Department of Pediatrics, University of Alabama at Birmingham 35294, USA
    Mol Genet Metab 64:62-9. 1998
    ..Further studies will be required to examine the role of D1 receptor activation in mediating c-fos expression and to explore the effects of cocaine on other IEGs...
  22. ncbi request reprint Rett syndrome: clinical correlates of the newly discovered gene
    A K Percy
    Department of Pediatrics, Neurology, and Neurobiology, University of Alabama at Birmingham, School of Medicine, Birmingham, AL 35233, USA
    Brain Dev 23:S202-5. 2001
    ....
  23. pmc Longevity in Rett syndrome: analysis of the North American Database
    Russell S Kirby
    School of Public Health, University of Alabama at Birmingham, Birmingham, AL, USA
    J Pediatr 156:135-138.e1. 2010
    ..To determine longevity in Rett syndrome (RTT) from a large cohort...
  24. pmc Dendritic spine pathologies in hippocampal pyramidal neurons from Rett syndrome brain and after expression of Rett-associated MECP2 mutations
    Christopher A Chapleau
    Department of Neurobiology, Evelyn McKnight Brain Institute, Civitan International Research Center, The University of Alabama at Birmingham, Birmingham, AL 35294 2182, USA
    Neurobiol Dis 35:219-33. 2009
    ....
  25. doi request reprint Linking process to outcome: are we training pediatricians to meet evolving health care needs?
    M Douglas Jones
    Department of Pediatrics, University of Colorado Denver, School of Medicine, Aurora, CO 80045, USA
    Pediatrics 123:S1-7. 2009
    ....
  26. ncbi request reprint Certification in child neurology: new directions for the twenty-first century
    Alan K Percy
    University of Alabama, Birmingham, AL, USA
    J Child Neurol 20:644-7. 2005
    ..Training pathways in child neurology are also reviewed as they have evolved in response to evident staff shortages and to promote entry into academic careers...
  27. ncbi request reprint Board certification in child neurology and neurology: cohort study
    Dorthea Juul
    American Board of Psychiatry and Neurology, Inc, Deerfield, IL 60015, USA
    J Child Neurol 20:25-7. 2005
    ..Overall, it was estimated that 82% of the 1994 child neurology and neurology graduates sought ABPN certification, and of these, 82% were successful...
  28. ncbi request reprint Certification in neurodevelopmental disabilities: the development of a new subspecialty and results of the initial examinations
    Frederick B Palmer
    University of Tennessee Health Science Center, Memphis, Tennessee 38105, USA
    Ment Retard Dev Disabil Res Rev 9:128-31. 2003
    ..After the "grandfathering period," candidates for the examination must complete ACGME-approved training programs in the subspecialty...
  29. ncbi request reprint Eating difficulties in girls with Rett syndrome compared with other developmental disabilities
    Janet Sugarman Isaacs
    Children s National Medical Center, Department of Genetics and Metabolism, Washington, DC, USA
    J Am Diet Assoc 103:224-30. 2003
    ....
  30. ncbi request reprint Rett syndrome: pathogenesis, diagnosis, strategies, therapies, and future research directions
    Kathleen M Deidrick
    Department of Health Psychology, University of Missouri Columbia, MO, USA
    J Child Neurol 20:708-17. 2005