David Penson

Summary

Affiliation: University of Southern California
Country: USA

Publications

  1. ncbi 5-year urinary and sexual outcomes after radical prostatectomy: results from the prostate cancer outcomes study
    David F Penson
    Department of Urology, Keck School of Medicine, University of Southern California, Los Angeles, California 90089, USA
    J Urol 173:1701-5. 2005
  2. ncbi Prostate cancer
    David F Penson
    Departments of Urology and Preventive Medicine, Keck School of Medicine, University of Southern California, 1441 Eastlake Avenue, Los Angeles, CA 90089, USA
    J Urol 177:2020-9. 2007
  3. ncbi Use of prostate-specific antigen in the follow-up of patients with localized prostate cancer: results of a nationwide survey of urologists
    David Penson
    Norris Comprehensive Cancer Center, Department of Urology, Keck School of Medicine, University of Southern California, Los Angeles, California 90089, USA
    Urology 68:80-4. 2006
  4. ncbi An update on randomized clinical trials in localized and locoregional prostate cancer
    David F Penson
    Urology and Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90089, USA
    Urol Oncol 23:280-8. 2005
  5. ncbi Prostate cancer: epidemiology and health-related quality of life
    David F Penson
    Department of Urology, University of Southern California Keck School of Medicine, Norris Comprehensive Cancer Center, Los Angeles, California 90089, USA
    Urology 72:S3-11. 2008
  6. ncbi Quality of life after therapy for localized prostate cancer
    David F Penson
    Departments of Urology and Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA
    Cancer J 13:318-26. 2007
  7. ncbi Assessing the quality of prostate cancer care
    David F Penson
    Department of Urology, Keck School of Medicine, University of Southern California, Los Angeles, California 90089, USA
    Curr Opin Urol 18:297-302. 2008
  8. ncbi The cost-effectiveness of combined androgen blockade with bicalutamide and luteinizing hormone releasing hormone agonist in men with metastatic prostate cancer
    David F Penson
    Department of Urology and Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California 90089, USA
    J Urol 174:547-52; discussion 552. 2005
  9. ncbi Sexual dysfunction and symptom impact in men with long-standing type 1 diabetes in the DCCT/EDIC cohort
    David F Penson
    Department of Urology, Keck School of Medicine, USC Norris Cancer Center, 1441 Eastlake Avenue, Los Angeles, CA 90089, USA
    J Sex Med 6:1969-78. 2009
  10. ncbi The economic burden of metastatic and prostate specific antigen progression in patients with prostate cancer: findings from a retrospective analysis of health plan data
    David F Penson
    Keck School of Medicine, University of Southern California, Los Angeles, California 90089, USA
    J Urol 171:2250-4. 2004

Research Grants

  1. Race, Comorbidity & Long Term Prostate Cancer Outcomes
    David Penson; Fiscal Year: 2007
  2. 2007 AUA/SBUR Summer Research Conference "Clinical Trials and Outcomes Research"
    David Penson; Fiscal Year: 2007

Detail Information

Publications80

  1. ncbi 5-year urinary and sexual outcomes after radical prostatectomy: results from the prostate cancer outcomes study
    David F Penson
    Department of Urology, Keck School of Medicine, University of Southern California, Los Angeles, California 90089, USA
    J Urol 173:1701-5. 2005
    ..In this study we assessed temporal changes in urinary and sexual function up to 5 years following radical prostatectomy in a population based cohort...
  2. ncbi Prostate cancer
    David F Penson
    Departments of Urology and Preventive Medicine, Keck School of Medicine, University of Southern California, 1441 Eastlake Avenue, Los Angeles, CA 90089, USA
    J Urol 177:2020-9. 2007
    ..We quantified the burden of prostate cancer in the United States by identifying trends in incidence, disease presentation, survival rates and use of health care resources, and by estimating the economic impact of the disease...
  3. ncbi Use of prostate-specific antigen in the follow-up of patients with localized prostate cancer: results of a nationwide survey of urologists
    David Penson
    Norris Comprehensive Cancer Center, Department of Urology, Keck School of Medicine, University of Southern California, Los Angeles, California 90089, USA
    Urology 68:80-4. 2006
    ..To perform a nationwide survey of urologists' opinions and behavior regarding the use of prostate-specific antigen (PSA) in prostate cancer follow-up and secondary treatment...
  4. ncbi An update on randomized clinical trials in localized and locoregional prostate cancer
    David F Penson
    Urology and Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90089, USA
    Urol Oncol 23:280-8. 2005
    ..Although there are numerous phase III studies ongoing in these areas, there are still large gaps in our understanding of the treatment of localized disease, and additional clinical trials are needed...
  5. ncbi Prostate cancer: epidemiology and health-related quality of life
    David F Penson
    Department of Urology, University of Southern California Keck School of Medicine, Norris Comprehensive Cancer Center, Los Angeles, California 90089, USA
    Urology 72:S3-11. 2008
    ..Therefore, practice patterns are heterogeneous and depend more on the availability of treatments than on the features of the disease itself...
  6. ncbi Quality of life after therapy for localized prostate cancer
    David F Penson
    Departments of Urology and Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA
    Cancer J 13:318-26. 2007
    ..Finally, I attempt to directly compare the quality-of-life effects of the various treatments to assist clinicians in advising patients with newly diagnosed localized prostate cancer...
  7. ncbi Assessing the quality of prostate cancer care
    David F Penson
    Department of Urology, Keck School of Medicine, University of Southern California, Los Angeles, California 90089, USA
    Curr Opin Urol 18:297-302. 2008
    ....
  8. ncbi The cost-effectiveness of combined androgen blockade with bicalutamide and luteinizing hormone releasing hormone agonist in men with metastatic prostate cancer
    David F Penson
    Department of Urology and Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California 90089, USA
    J Urol 174:547-52; discussion 552. 2005
    ..The goal of this study was to assess the cost-effectiveness of CAB with bicalutamide and LH-RH agonist therapy to LH-RH agonist therapy alone...
  9. ncbi Sexual dysfunction and symptom impact in men with long-standing type 1 diabetes in the DCCT/EDIC cohort
    David F Penson
    Department of Urology, Keck School of Medicine, USC Norris Cancer Center, 1441 Eastlake Avenue, Los Angeles, CA 90089, USA
    J Sex Med 6:1969-78. 2009
    ..Male sexual dysfunction is a common complication of diabetes (DM), but the relative impact of erectile dysfunction (ED), orgasmic dysfunction (OD), and/or decreased libido (DL) on global sexual bother has not been assessed...
  10. ncbi The economic burden of metastatic and prostate specific antigen progression in patients with prostate cancer: findings from a retrospective analysis of health plan data
    David F Penson
    Keck School of Medicine, University of Southern California, Los Angeles, California 90089, USA
    J Urol 171:2250-4. 2004
    ..We evaluated the economic burden of metastatic and prostate specific antigen (PSA) progression in patients with prostate cancer (CaP) using a cancer registry linked administrative database...
  11. ncbi Changes in specific domains of sexual function and sexual bother after radical prostatectomy
    Jesse D Le
    University of California San Francisco, San Francisco, CA, USA
    BJU Int 106:1022-9. 2010
    ....
  12. ncbi Impact of ethnicity on primary treatment choice and mortality in men with prostate cancer: data from CaPSURE
    Kelvin A Moses
    Department of Urology, Emory University School of Medicine, 1365 Clifton Rd, NE, Building B, Atlanta, GA 30322, USA
    J Clin Oncol 28:1069-74. 2010
    ..Additional research on the influence of patient/physician education and perception and the role that socioeconomic factors play in mortality from prostate cancer may be areas of focus for public health initiatives...
  13. ncbi Prostate cancer outcomes among older men: insurance status comparisons results from CaPSURE database
    N Sadetsky
    Department of Urology, UCSF Comprehensive Cancer Center, University of California San Francisco, CA 94115, USA
    Prostate Cancer Prostatic Dis 11:280-7. 2008
    ..Future explorations of associations between health care delivery system, cancer care and outcomes are needed...
  14. ncbi Prostate-sparing cystectomy: a review of the oncologic and functional outcomes. Contraindicated in patients with bladder cancer
    John P Stein
    Department of Urology, Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, California 90089, USA
    Urol Oncol 27:466-72. 2009
    ..Prostate-sparing techniques have recently become an alternative surgical approach for the treatment of the disease. We review the literature regarding the oncologic and functional outcomes for prostate-sparing approaches...
  15. ncbi Radical cystectomy with extended lymphadenectomy: evaluating separate package versus en bloc submission for node positive bladder cancer
    John P Stein
    Department of Urology, University of Southern California, Norris Comprehensive Cancer Center, Los Angeles, California 90089, USA
    J Urol 177:876-81; discussion 881-2. 2007
    ..We evaluated the clinical and pathological findings resulting from this modification...
  16. ncbi Racial/Ethnic differences in functional outcomes in the 5 years after diagnosis of localized prostate cancer
    Terri Kang Johnson
    University of Southern California Keck School of Medicine, Dept of Preventive Medicine, 1441 Eastlake Ave, Rm 3427A, MC9175, Los Angeles, CA 90089 9175, USA
    J Clin Oncol 22:4193-201. 2004
    ..We investigated racial/ethnic differences in functional outcomes up to 5 years after diagnosis among men with aggressively treated localized prostate cancer...
  17. ncbi Long-term oncological outcomes in women undergoing radical cystectomy and orthotopic diversion for bladder cancer
    John P Stein
    Department of Urology, Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, California 90089, USA
    J Urol 181:2052-8; discussion 2058-9. 2009
    ..We compared oncological outcomes in women undergoing radical cystectomy and orthotopic diversion for bladder transitional cell carcinoma...
  18. ncbi Trends in the treatment of localized prostate cancer using supplemented cancer registry data
    Ann S Hamilton
    Keck School of Medicine, University of Southern California, Los Angeles, CA, USA
    BJU Int 107:576-84. 2011
    ..To conduct an analysis of localized prostate cancer treatment in the USA between 1998 and 2002...
  19. ncbi Discussing quality-of-life issues with a patient newly diagnosed with prostate cancer
    John L Gore
    Department of Urology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA 90095, USA
    Nat Clin Pract Urol 3:449-52. 2006
    ..A 66-year-old man with hypertension, hyperlipidemia, and benign prostatic hyperplasia presented for evaluation of an elevated PSA level of 6.2 ng/ml...
  20. ncbi Quality of life in patients with localized prostate cancer
    Marcus L Quek
    Department of Urology, Keck School of Medicine at the University of Southern California, Los Angeles, CA 90089, USA
    Urol Oncol 23:208-15. 2005
    ..We will begin by examining the established HRQOL instruments for use in localized prostate cancer. We will then discuss the effect of various treatments on QOL and review the literature comparing HRQOL outcomes between therapies...
  21. ncbi Invasive T1 bladder cancer: indications and rationale for radical cystectomy
    John P Stein
    Department of Urology, University of Southern California Keck School of Medicine, Norris Comprehensive Cancer Center, Los Angeles, CA 90089, USA
    BJU Int 102:270-5. 2008
    ..This review provides a rationale for a radical cystectomy in patients with high-risk, invasive T1 bladder cancer...
  22. ncbi Salvage radical prostatectomy: quality of life outcomes and long-term oncological control of radiorecurrent prostate cancer
    Kristin M Sanderson
    Department of Urology, Keck School of Medicine, University of Southern California, University of Southern California Norris Cancer Center, Los Angeles, California 90089, USA
    J Urol 176:2025-31; discussion 2031-2. 2006
    ..Using a standardized questionnaire we also evaluate outcome data regarding the long-term sexual and urinary effects of salvage radical prostatectomy...
  23. ncbi Quality of life after treatment for prostate cancer
    David F Penson
    Department of Urology, David Geffen School of Medicine and School of Public Health, University of California, Los Angeles 66-121CHS, Box 951738, Los Angeles, CA 90095-1738, USA
    Curr Urol Rep 4:185-95. 2003
    ..Better information regarding the potential impact of prostate cancer treatment on quality of life will improve medical decision-making...
  24. ncbi Quality of life in young men after radical prostatectomy
    J L Wright
    Department of Urology, University of Washington School of Medicine, Seattle, WA 98195, USA
    Prostate Cancer Prostatic Dis 11:67-73. 2008
    ..Baseline scores are strongly associated with post-RP scores and severity of declines. Current relationships and use of sexual aids have significant roles in post-RP bother...
  25. ncbi Quality of life issues in bladder cancer patients following cystectomy and urinary diversion
    Michael P Porter
    Department of Urology, University of Washington, H220 Health Sciences Center, Box 357183, Seattle, WA 98195-7183, USA
    Urol Clin North Am 32:207-16. 2005
    ..Patients will then be able to make a more fully informed decision on the most appropriate form of therapy for this serious life-altering disease...
  26. ncbi Predictors of intravesical therapy for nonmuscle invasive bladder cancer: results from the surveillance, epidemiology and end results program 2003 patterns of care project
    George J Huang
    Department of Urology, Keck School of Medicine, University of Southern California, Los Angeles, California, USA
    J Urol 180:520-4; discussion 524. 2008
    ..We examined patterns of intravesical therapy use in nonmuscle invasive bladder cancer in 2003 to determine whether disparities remained in the quality of cancer care...
  27. ncbi Treatment outcomes in localized prostate cancer: a patient-oriented approach
    Richard Lee
    Department of Urology, University of Washington School of Medicine, Seattle, WA, USA
    Semin Urol Oncol 20:63-73. 2002
    ....
  28. ncbi Benign prostatic hyperplasia evaluation and management by urologists and primary care physicians: practice patterns from the observational BPH registry
    John T Wei
    Department of Urology, University of Michigan and i3 Drug Safety, Ann Arbor, Michigan 48109 2800, USA
    J Urol 186:971-6. 2011
    ..We examined the evaluation of and management for lower urinary tract symptoms/benign prostatic hyperplasia by physician specialty (urologist vs primary care physician)...
  29. ncbi Evaluating use patterns of and adherence to medications for benign prostatic hyperplasia
    Michael B Nichol
    Department of Clinical Pharmacy and Pharmaceutical Economics and Policy, University of Southern California, Los Angeles, California 90089, USA
    J Urol 181:2214-21; discussion 2221-2. 2009
    ..We investigated adherence to benign prostatic hyperplasia medications in a California Medicaid population...
  30. ncbi Clinical outcomes and recurrence predictors of lymph node positive urothelial cancer after cystectomy
    Harman M Bruins
    Department of Urology, Keck School of Medicine, University of Southern California, Los Angeles, California, USA
    J Urol 182:2182-7. 2009
    ..We examined outcomes in patients with low volume lymph node metastasis and identified variables associated with disease recurrence...
  31. ncbi Health related quality of life for men treated for localized prostate cancer with long-term followup
    George J Huang
    Department of Urology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
    J Urol 183:2206-12. 2010
    ..Long-term changes after treatment are not yet fully understood. We characterized health related quality of life evolution from baseline to 4 years after treatment...
  32. ncbi Health related quality of life after radical cystectomy and urinary diversion for bladder cancer: a systematic review and critical analysis of the literature
    Michael P Porter
    Department of Urology, University of Washington, Seattle 98195 7183, USA
    J Urol 173:1318-22. 2005
    ..It is unclear whether the existing body of literature supports this assumption...
  33. ncbi The relationship among lower urinary tract symptoms, prostate specific antigen and erectile dysfunction in men with benign prostatic hyperplasia: results from the proscar long-term efficacy and safety study
    Sung Hyun Paick
    Department of Urology, University of Washington School of Medicine and Harborview Medical Center, Seattle, Washington 98104, USA
    J Urol 173:903-7. 2005
    ..The absence of a relationship between PSA and ED highlights the need for further investigation into the mechanisms of benign prostatic hyperplasia related sexual dysfunction...
  34. ncbi Racial variation in the incidence of squamous cell carcinoma of the bladder in the United States
    Michael P Porter
    Department of Urology, College of Medicine and Department of Epidemiology, School of Public Health and Community Medicine, University of Washington, Seattle, USA
    J Urol 168:1960-3. 2002
    ..CONCLUSIONS: Squamous cell carcinoma of the bladder appears to be twice as common in black as in white individuals in the United States...
  35. ncbi Pay for performance: rationale and potential implications for urology
    Chris M Gonzalez
    Department of Urology, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, USA
    J Urol 178:402-8. 2007
    ..The rationale behind this initiative and what it means for the practicing urologist are discussed...
  36. ncbi The cost-effectiveness of treatment for varicocele related infertility
    David F Penson
    Department of Urology, University of Washington School of Medicine, Seattle, Washington, USA
    J Urol 168:2490-4. 2002
    ..The findings of this study should be used to counsel infertile patients with varicocele that immediate IVF is not cost-effective...
  37. ncbi Comparison of the International Index of Erectile Function erectile domain scores and nocturnal penile tumescence and rigidity measurements: does one predict the other?
    Claire C Yang
    Department of Urology, University of Washington, Seattle, WA 98195 6510, USA
    BJU Int 98:105-9; discussion 109. 2006
    ..To describe the relationship between the International Index of Erectile Function (IIEF) erectile domain score, and nocturnal penile tumescence and rigidity values measured by RigiScan (Timm Medical Technologies, Eden Prairie, MN)...
  38. ncbi Cigarette smoking and risk of prostate cancer in middle-aged men
    Lora A Plaskon
    Department of Urology, University of Washington, Seattle, USA
    Cancer Epidemiol Biomarkers Prev 12:604-9. 2003
    ..Given that smoking cessation seems to reduce these risks, results from this study have public health ramifications and suggest that prostate cancer should be added to the list of tumors for which cigarette smoking is a risk factor...
  39. ncbi Prostate cancer on the Internet--information or misinformation?
    Peter C Black
    University of Southern California Norris Cancer Center, Los Angeles, California, USA
    J Urol 175:1836-42; discussion 1842. 2006
    ..We assessed the quality of information available to patients on prostate cancer on the Internet...
  40. ncbi Pathological guidelines for orthotopic urinary diversion in women with bladder cancer: a review of the literature
    John P Stein
    Department of Urology, University of Southern California, Norris Comprehensive Cancer Center, Los Angeles, California 90089, USA
    J Urol 178:756-60. 2007
    ..We reviewed the literature regarding the incidence of urethral involvement, the risk factors for urethral involvement and the incidence of urethral recurrence in women undergoing orthotopic urinary diversion for bladder cancer...
  41. ncbi Symptoms and inflammation in chronic prostatitis/chronic pelvic pain syndrome
    John N Krieger
    Department of Urology, School of Medicine, University of Washington, Seattle, Washington, USA
    Urology 60:959-63. 2002
    ....
  42. ncbi Erectile aid use by men treated for localized prostate cancer
    Jonathan Bergman
    Department of Urology, University of California Los Angeles, Los Angeles, California 90095 1738, USA
    J Urol 182:649-54. 2009
    ..We evaluated associations between demographic and clinical characteristics, quality of life outcome measures and erectile aids in men treated for localized prostate cancer...
  43. ncbi The physical burden of prostate cancer
    David F Penson
    VA Puget Sound Health Care System, Section of Urology, 112 UR 1660 S Columbian Way, Seattle, WA 98108, USA
    Urol Clin North Am 30:305-13. 2003
    ..By being cognizant of the physical impact of prostate cancer on quality of life, providers can address patients' problems early in their course of treatment and maximize patients' HRQOL and overall satisfaction with care...
  44. ncbi 13-year outcomes following treatment for clinically localized prostate cancer in a population based cohort
    Peter C Albertsen
    University of Connecticut Health Center, Farmington 06030 3955, and St Francis Hospital and Medical Center, Hartford, Connecticut, USA
    J Urol 177:932-6. 2007
    ....
  45. ncbi Longitudinal differences in disease specific quality of life in men with erectile dysfunction: results from the Exploratory Comprehensive Evaluation of Erectile Dysfunction study
    David M Latini
    Department of Urology and Urology Outcomes Research Group, Univeristy of California, San Francisco, USA
    J Urol 169:1437-42. 2003
    ....
  46. ncbi Is quality of life different for men with erectile dysfunction and prostate cancer compared to men with erectile dysfunction due to other causes? Results from the ExCEED data base
    David F Penson
    Section of Urology, VA Puget Sound Health Care System and Departmnent Urology, University of Washington, Seattle, USA
    J Urol 169:1458-61. 2003
    ..Lake Forest, Illinois) data base, which is a multicenter, observational disease registry of men with erectile dysfunction...
  47. ncbi General quality of life 2 years following treatment for prostate cancer: what influences outcomes? Results from the prostate cancer outcomes study
    David F Penson
    Section of Urology, VA Puget Sound Health Care System and the Department of Urology, University of Washington, Seattle, WA 98108, USA
    J Clin Oncol 21:1147-54. 2003
    ..The goal of this study was to determine the relationship between primary treatment, urinary dysfunction, sexual dysfunction, and general health-related quality of life (HRQOL) in prostate cancer...
  48. ncbi Impact of PSA screening on the incidence of advanced stage prostate cancer in the United States: a surveillance modeling approach
    Ruth Etzioni
    Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109 1024, USA
    Med Decis Making 28:323-31. 2008
    ..The objective was to quantify this link between PSA screening and the decline in distant stage incidence...
  49. ncbi Five-year outcomes after prostatectomy or radiotherapy for prostate cancer: the prostate cancer outcomes study
    Arnold L Potosky
    Division of Cancer Control and Population Sciences, National Cancer Institute, EPN Rm 4005, 6130 Executive Blvd, MSC 7344, Bethesda, MD 20892 7344, USA
    J Natl Cancer Inst 96:1358-67. 2004
    ..We present treatment-specific quality-of-life outcomes for prostate cancer patients 5 years after initial diagnosis...
  50. ncbi Trends in treatment costs for localized prostate cancer: the healthy screenee effect
    Steven B Zeliadt
    Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109 1024, USA
    Med Care 45:154-9. 2007
    ..We sought to obtain estimates of trends in initial treatment costs during the prostate-specific antigen (PSA) era that account for the changing patient case-mix associated with screening...
  51. ncbi Health-related quality of life for men with prostate cancer and diabetes: a longitudinal analysis from CaPSURE
    David M Latini
    Scott Department of Urology and Dan L Duncan Cancer Center, Baylor College of Medicine, Houston, Texas, USA
    Urology 68:1242-7. 2006
    ....
  52. ncbi Clinical and psychosocial characteristics of men with erectile dysfunction: baseline data from ExCEED
    David M Latini
    Scott Department of Urology, Baylor College of Medicine, Houston, TX, USA
    J Sex Med 3:1059-67. 2006
    ..Erectile dysfunction (ED) is associated with psychological impairment, and further research is required to understand their relationship...
  53. ncbi Race independently predicts prostate specific antigen testing frequency following a prostate carcinoma diagnosis
    Steven B Zeliadt
    Fred Hutchinson Cancer Research Center, Seattle, Washington 98109-1024, USA
    Cancer 98:496-503. 2003
    ..Further research is needed to identify the reasons for the racial disparity in PSA surveillance and to design interventions to lessen these differences...
  54. ncbi Survival benefit associated with adjuvant androgen deprivation therapy combined with radiotherapy for high- and low-risk patients with nonmetastatic prostate cancer
    Steven B Zeliadt
    Fred Hutchinson Cancer Research Center, Health Services Department, University of Washington School of Public Health and Community Medicine, Seattle, WA 98109 1024, USA
    Int J Radiat Oncol Biol Phys 66:395-402. 2006
    ..This study examines the effectiveness of adjuvant ADT combined with radiotherapy for a wide range of patients treated in the 1990s...
  55. ncbi Do impotent men with diabetes have more severe erectile dysfunction and worse quality of life than the general population of impotent patients? Results from the Exploratory Comprehensive Evaluation of Erectile Dysfunction (ExCEED) database
    David F Penson
    Section of Urology, VA Puget Sound Health Care System, and the Department of Urology, University of Washington, Seattle, Washington, USA
    Diabetes Care 26:1093-9. 2003
    ..The primary objective of this study was to compare disease-specific health-related quality of life (HRQOL) and severity of ED in impotent men with and without diabetes...
  56. ncbi How well does the Partin nomogram predict pathological stage after radical prostatectomy in a community based population? Results of the cancer of the prostate strategic urological research endeavor
    David F Penson
    Section of Urology, Veterans Affairs Puget Sound Health Care System and Department of Urology, University of Washington, Seattle, Washington, USA
    J Urol 167:1653-7; discussion 1657-8. 2002
    ..We assessed the performance of the nomogram in the Cancer of the Prostate Strategic Urological Research Endeavor, a nationwide, community based observational disease registry of men with prostate cancer...
  57. ncbi Lifetime implications and cost-effectiveness of using finasteride to prevent prostate cancer
    Steven B Zeliadt
    Fred Hutchinson Cancer Research Center, Seattle, Wash 98109, USA
    Am J Med 118:850-7. 2005
    ....
  58. ncbi Prostate cancer and the Will Rogers phenomenon
    Peter C Albertsen
    University of Connecticut Health Center, 263 Farmington Avenue, Farmington, CT 06030 3955, USA
    J Natl Cancer Inst 97:1248-53. 2005
    ..To determine whether this decline is in part a result of Gleason score reclassification during the same time period, we documented the potential impact of reclassification between 1992 and 2002 on clinical outcomes...
  59. ncbi Overdiagnosis due to prostate-specific antigen screening: lessons from U.S. prostate cancer incidence trends
    Ruth Etzioni
    Program in Biostatistics, Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
    J Natl Cancer Inst 94:981-90. 2002
    ..Overdiagnosis was defined as the detection of prostate cancer through PSA testing that otherwise would not have been diagnosed within the patient's lifetime...
  60. ncbi Racial disparity in primary and adjuvant treatment for nonmetastatic prostate cancer: SEER-Medicare trends 1991 to 1999
    Steven B Zeliadt
    Department of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109 1024, USA
    Urology 64:1171-6. 2004
    ..To assess trends in the initial care of nonmetastatic prostate cancer, including the use of primary and adjuvant androgen deprivation therapy (ADT), using population-based treatment claims from 1991 to 1999...
  61. ncbi Psychological impact of erectile dysfunction: validation of a new health related quality of life measure for patients with erectile dysfunction
    David M Latini
    Department of Urology and Urology Outcomes Research Group, University of California, San Francisco, USA
    J Urol 168:2086-91. 2002
    ....
  62. ncbi Dietary patterns, supplement use, and the risk of symptomatic benign prostatic hyperplasia: results from the prostate cancer prevention trial
    Alan R Kristal
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
    Am J Epidemiol 167:925-34. 2008
    ..A diet low in fat and red meat and high in protein and vegetables, as well as regular alcohol consumption, may reduce the risk of symptomatic BPH...
  63. ncbi Phase III prevention trial of fenretinide in patients with resected non-muscle-invasive bladder cancer
    Anita L Sabichi
    Department of Clinical Cancer Prevention, The University of Texas M D Anderson Cancer Center, Houston, TX 77230 1439, USA
    Clin Cancer Res 14:224-9. 2008
    ..The study aims to evaluate the efficacy and toxicity of fenretinide in preventing tumor recurrence in patients with transitional cell carcinoma (TCC) of the bladder...
  64. ncbi Quantifying the role of PSA screening in the US prostate cancer mortality decline
    Ruth Etzioni
    Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
    Cancer Causes Control 19:175-81. 2008
    ..To quantify the plausible contribution of prostate-specific antigen (PSA) screening to the nearly 30% decline in the US prostate cancer mortality rate observed during the 1990s...
  65. ncbi Prostate-specific antigen and free prostate-specific antigen in the early detection of prostate cancer: do combination tests improve detection?
    Ruth Etzioni
    Program in Biostatistics, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, M2 B230, Seattle, WA 98109 1024, USA
    Cancer Epidemiol Biomarkers Prev 13:1640-5. 2004
    ..The combined use of free and total prostate-specific antigen (PSA) in early detection of prostate cancer has been controversial. This article systematically evaluates the discriminating capacity of a large number of combination tests...
  66. ncbi Cross-sectional and longitudinal comparisons of health-related quality of life between patients with prostate carcinoma and matched controls
    Richard M Hoffman
    Medicine Service, New Mexico Veterans Affairs Health Care System, Albuquerque, NM 87108, USA
    Cancer 101:2011-9. 2004
    ..Prostate carcinoma and treatments affect health-related quality of life (HRQOL). The authors prospectively compared prostate and general HRQOL between prostate carcinoma cases and an age-matched and ethnicity-matched control group...
  67. ncbi Steroid hormones and hormone-related genetic and lifestyle characteristics as risk factors for benign prostatic hyperplasia: review of epidemiologic literature
    Marian L Neuhouser
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109-1024, USA
    Urology 64:201-11. 2004
  68. ncbi Long-term effects of finasteride on prostate specific antigen levels: results from the prostate cancer prevention trial
    Ruth D Etzioni
    Fred Hutchinson Cancer Research Center, Seattle, Washington 98109 1024, USA
    J Urol 174:877-81. 2005
    ..We estimated the long-term effects of finasteride on PSA in men with and without a prostate cancer diagnosis at the end of the study...
  69. ncbi Laparoscopic urological oncology: here come the outcomes!
    David F Penson
    J Urol 174:1174. 2005
  70. ncbi Variations in prostate cancer patterns of care: is it the quality of care or the quality of the data?
    David F Penson
    J Clin Oncol 23:7783-4. 2005
  71. ncbi Why do men choose one treatment over another?: a review of patient decision making for localized prostate cancer
    Steven B Zeliadt
    Public Health Sciences Division, Fred Hutchinson Cancer Center, Seattle, Washington 98109, USA
    Cancer 106:1865-74. 2006
    ..Considerable progress is needed in helping patients fully understand how to balance the complex issues surrounding prostate cancer treatment decision making...
  72. ncbi Combining longitudinal studies of PSA
    Lurdes Y T Inoue
    University of Washington, Department of Biostatistics, F 600 Health Sciences Building, Campus Mail Stop 357232, Seattle, WA 98195, USA
    Biostatistics 5:483-500. 2004
    ....
  73. ncbi Laparoscopic partial nephrectomy and prostatectomy: weighing the costs and the benefits
    David F Penson
    J Urol 172:6-7. 2004
  74. ncbi Validation of increasing prostate specific antigen as a predictor of prostate cancer death after treatment of localized prostate cancer with surgery or radiation
    Peter C Albertsen
    University of Connecticut Health Center, Farmington, Connecticut 06030 3955, USA
    J Urol 171:2221-5. 2004
    ..This study documents patterns of PSA recurrence after surgery or radiation to treat localized prostate cancer and quantifies the extent to which an increasing PSA predicts death from prostate cancer...
  75. ncbi Longitudinal differences in psychological outcomes for men with erectile dysfunction: results from ExCEED
    David M Latini
    Scott Department of Urology, Baylor College of Medicine, Houston, TX, USA
    J Sex Med 3:1068-76. 2006
    ..The direction of the relationship between psychological adjustment and erectile dysfunction (ED) is unclear and may differ for different men, and few studies have examined psychological outcomes for men receiving ED treatment...
  76. ncbi PSA screening and elderly men
    Eric A Singer
    JAMA 297:949; author reply 949-50. 2007
  77. ncbi Pharmacoeconomics of available treatment options for metastatic prostate cancer
    Steven B Zeliadt
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA
    Pharmacoeconomics 25:309-27. 2007
    ..It is essential that we address the weaknesses in our understanding of the economic consequences of therapies for prostate cancer, and find ways to include economic information into the process of determining optimal therapy...
  78. ncbi On the importance of race, socioeconomic status and comorbidity when evaluating quality of life in men with prostate cancer
    Scott D Ramsey
    Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, Seattle, WA 98109, USA
    J Urol 177:1992-9. 2007
    ..To determine the completeness and quality of available health related quality of life information we performed a review of health related quality of life studies, assessing what information was and was not reported...
  79. ncbi Health related quality of life in men with prostate cancer
    David F Penson
    Section of Urology, VA Puget Sound Health Care System, Seattle, WA, USA
    J Urol 169:1653-61. 2003
    ..This information is of critical importance when counseling men with newly diagnosed prostate cancer regarding treatment choices and is also helpful in setting appropriate expectations for men with metastatic disease...
  80. ncbi An ecologic study of prostate-specific antigen screening and prostate cancer mortality in nine geographic areas of the United States
    Pamela A Shaw
    Fred Hutchinson Cancer Research Center, Seattle, WA, 98109-1024, USA
    Am J Epidemiol 160:1059-69. 2004
    ..Ecologic analyses of the effectiveness of PSA testing should be interpreted with caution...

Research Grants3

  1. Race, Comorbidity & Long Term Prostate Cancer Outcomes
    David Penson; Fiscal Year: 2007
    ..Specifically, it will help newly-diagnosed patients make more informed decisions regarding treatment and will help researchers design novel interventions to improve the quality of life of prostate cancer survivors. ..
  2. 2007 AUA/SBUR Summer Research Conference "Clinical Trials and Outcomes Research"
    David Penson; Fiscal Year: 2007
    ....