Research Topics
| D F PensonSummaryAffiliation: University of Washington Country: USA Publications
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Detail Information
Publications
The association between socioeconomic status, health insurance coverage, and quality of life in men with prostate cancerD F Penson
Department of Urology, University of Washington School of Medicine, Seattle, WA, USA
J Clin Epidemiol 54:350-8. 2001..These findings have important ramifications for clinicians, researchers and policy makers...
The physical burden of prostate cancerDavid F Penson
VA Puget Sound Health Care System, Section of Urology, 112 UR 1660 S Columbian Way, Seattle, WA 98108, USA
Urol Clin North Am 30:305-13. 2003..By being cognizant of the physical impact of prostate cancer on quality of life, providers can address patients' problems early in their course of treatment and maximize patients' HRQOL and overall satisfaction with care...
Lessons learnt about early prostate cancer from large scale databases: population-based pearls of wisdomDavid F Penson
University of Washington, Seattle, WA 98106, USA
Surg Oncol 11:3-11. 2002..Information gathered from large, administrative databases will be helpful when counseling patients regarding their treatments options for localized prostate cancer and in identifying future directions for prostate cancer research...
Quality of life following prostate cancer treatmentsD F Penson
Department of Urology, University of Washington School of Medicine, VAPSHCS Section of Urology, 112 UR, 1660 South Columbian Way, Seattle, WA 98108, USA
Curr Urol Rep 1:71-7. 2000..Patients need to be informed of the possible impact of therapy on quality of life when choosing treatment...
Do impotent men with diabetes have more severe erectile dysfunction and worse quality of life than the general population of impotent patients? Results from the Exploratory Comprehensive Evaluation of Erectile Dysfunction (ExCEED) databaseDavid F Penson
Section of Urology, VA Puget Sound Health Care System, and the Department of Urology, University of Washington, Seattle, Washington, USA
Diabetes Care 26:1093-9. 2003..The primary objective of this study was to compare disease-specific health-related quality of life (HRQOL) and severity of ED in impotent men with and without diabetes...
General quality of life 2 years following treatment for prostate cancer: what influences outcomes? Results from the prostate cancer outcomes studyDavid F Penson
Section of Urology, VA Puget Sound Health Care System and the Department of Urology, University of Washington, Seattle, WA 98108, USA
J Clin Oncol 21:1147-54. 2003..The goal of this study was to determine the relationship between primary treatment, urinary dysfunction, sexual dysfunction, and general health-related quality of life (HRQOL) in prostate cancer...
Relationship of first-year costs of treating localized prostate cancer to initial choice of therapy and stage at diagnosis: results from the CAPSURE databaseD F Penson
Department of Urology, University of Washington School of Medicine, Seattle, Washington, USA
Urology 57:499-503. 2001..This supports the notion that cost savings may be possible with earlier detection of disease or by minimizing the use of hormonal adjuvant therapy...
Prostate cancer on the Internet--information or misinformation?Peter C Black
University of Southern California Norris Cancer Center, Los Angeles, California, USA
J Urol 175:1836-42; discussion 1842. 2006..We assessed the quality of information available to patients on prostate cancer on the Internet...
Prostate cancer and the Will Rogers phenomenonPeter C Albertsen
University of Connecticut Health Center, 263 Farmington Avenue, Farmington, CT 06030 3955, USA
J Natl Cancer Inst 97:1248-53. 2005..To determine whether this decline is in part a result of Gleason score reclassification during the same time period, we documented the potential impact of reclassification between 1992 and 2002 on clinical outcomes...
Quality of life in patients with localized prostate cancerMarcus L Quek
Department of Urology, Keck School of Medicine at the University of Southern California, Los Angeles, CA 90089, USA
Urol Oncol 23:208-15. 2005..We will begin by examining the established HRQOL instruments for use in localized prostate cancer. We will then discuss the effect of various treatments on QOL and review the literature comparing HRQOL outcomes between therapies...
Quality of life issues in bladder cancer patients following cystectomy and urinary diversionMichael P Porter
Department of Urology, University of Washington, H220 Health Sciences Center, Box 357183, Seattle, WA 98195-7183, USA
Urol Clin North Am 32:207-16. 2005..Patients will then be able to make a more fully informed decision on the most appropriate form of therapy for this serious life-altering disease...
5-year urinary and sexual outcomes after radical prostatectomy: results from the prostate cancer outcomes studyDavid F Penson
Department of Urology, Keck School of Medicine, University of Southern California, Los Angeles, California 90089, USA
J Urol 173:1701-5. 2005..In this study we assessed temporal changes in urinary and sexual function up to 5 years following radical prostatectomy in a population based cohort...
Health related quality of life after radical cystectomy and urinary diversion for bladder cancer: a systematic review and critical analysis of the literatureMichael P Porter
Department of Urology, University of Washington, Seattle 98195 7183, USA
J Urol 173:1318-22. 2005..It is unclear whether the existing body of literature supports this assumption...
The relationship among lower urinary tract symptoms, prostate specific antigen and erectile dysfunction in men with benign prostatic hyperplasia: results from the proscar long-term efficacy and safety studySung Hyun Paick
Department of Urology, University of Washington School of Medicine and Harborview Medical Center, Seattle, Washington 98104, USA
J Urol 173:903-7. 2005..The absence of a relationship between PSA and ED highlights the need for further investigation into the mechanisms of benign prostatic hyperplasia related sexual dysfunction...
Racial disparity in primary and adjuvant treatment for nonmetastatic prostate cancer: SEER-Medicare trends 1991 to 1999Steven B Zeliadt
Department of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109 1024, USA
Urology 64:1171-6. 2004..To assess trends in the initial care of nonmetastatic prostate cancer, including the use of primary and adjuvant androgen deprivation therapy (ADT), using population-based treatment claims from 1991 to 1999...
Comparison of the International Index of Erectile Function erectile domain scores and nocturnal penile tumescence and rigidity measurements: does one predict the other?Claire C Yang
Department of Urology, University of Washington, Seattle, WA 98195 6510, USA
BJU Int 98:105-9; discussion 109. 2006..To describe the relationship between the International Index of Erectile Function (IIEF) erectile domain score, and nocturnal penile tumescence and rigidity values measured by RigiScan (Timm Medical Technologies, Eden Prairie, MN)...
Discussing quality-of-life issues with a patient newly diagnosed with prostate cancerJohn L Gore
Department of Urology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA 90095, USA
Nat Clin Pract Urol 3:449-52. 2006..A 66-year-old man with hypertension, hyperlipidemia, and benign prostatic hyperplasia presented for evaluation of an elevated PSA level of 6.2 ng/ml...
Quantifying the role of PSA screening in the US prostate cancer mortality declineRuth Etzioni
Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
Cancer Causes Control 19:175-81. 2008..To quantify the plausible contribution of prostate-specific antigen (PSA) screening to the nearly 30% decline in the US prostate cancer mortality rate observed during the 1990s...
On the importance of race, socioeconomic status and comorbidity when evaluating quality of life in men with prostate cancerScott D Ramsey
Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, Seattle, WA 98109, USA
J Urol 177:1992-9. 2007..To determine the completeness and quality of available health related quality of life information we performed a review of health related quality of life studies, assessing what information was and was not reported...
13-year outcomes following treatment for clinically localized prostate cancer in a population based cohortPeter C Albertsen
University of Connecticut Health Center, Farmington 06030 3955, and St Francis Hospital and Medical Center, Hartford, Connecticut, USA
J Urol 177:932-6. 2007....
Health-related quality of life for men with prostate cancer and diabetes: a longitudinal analysis from CaPSUREDavid M Latini
Scott Department of Urology and Dan L Duncan Cancer Center, Baylor College of Medicine, Houston, Texas, USA
Urology 68:1242-7. 2006....
Longitudinal differences in psychological outcomes for men with erectile dysfunction: results from ExCEEDDavid M Latini
Scott Department of Urology, Baylor College of Medicine, Houston, TX, USA
J Sex Med 3:1068-76. 2006..The direction of the relationship between psychological adjustment and erectile dysfunction (ED) is unclear and may differ for different men, and few studies have examined psychological outcomes for men receiving ED treatment...
Clinical and psychosocial characteristics of men with erectile dysfunction: baseline data from ExCEEDDavid M Latini
Scott Department of Urology, Baylor College of Medicine, Houston, TX, USA
J Sex Med 3:1059-67. 2006..Erectile dysfunction (ED) is associated with psychological impairment, and further research is required to understand their relationship...
Salvage radical prostatectomy: quality of life outcomes and long-term oncological control of radiorecurrent prostate cancerKristin M Sanderson
Department of Urology, Keck School of Medicine, University of Southern California, University of Southern California Norris Cancer Center, Los Angeles, California 90089, USA
J Urol 176:2025-31; discussion 2031-2. 2006..Using a standardized questionnaire we also evaluate outcome data regarding the long-term sexual and urinary effects of salvage radical prostatectomy...
Survival benefit associated with adjuvant androgen deprivation therapy combined with radiotherapy for high- and low-risk patients with nonmetastatic prostate cancerSteven B Zeliadt
Fred Hutchinson Cancer Research Center, Health Services Department, University of Washington School of Public Health and Community Medicine, Seattle, WA 98109 1024, USA
Int J Radiat Oncol Biol Phys 66:395-402. 2006..This study examines the effectiveness of adjuvant ADT combined with radiotherapy for a wide range of patients treated in the 1990s...
An ecologic study of prostate-specific antigen screening and prostate cancer mortality in nine geographic areas of the United StatesPamela A Shaw
Fred Hutchinson Cancer Research Center, Seattle, WA, 98109-1024, USA
Am J Epidemiol 160:1059-69. 2004..Ecologic analyses of the effectiveness of PSA testing should be interpreted with caution...
Racial/Ethnic differences in functional outcomes in the 5 years after diagnosis of localized prostate cancerTerri Kang Johnson
University of Southern California Keck School of Medicine, Dept of Preventive Medicine, 1441 Eastlake Ave, Rm 3427A, MC9175, Los Angeles, CA 90089 9175, USA
J Clin Oncol 22:4193-201. 2004..We investigated racial/ethnic differences in functional outcomes up to 5 years after diagnosis among men with aggressively treated localized prostate cancer...
Treatment outcomes in localized prostate cancer: a patient-oriented approachRichard Lee
Department of Urology, University of Washington School of Medicine, Seattle, WA, USA
Semin Urol Oncol 20:63-73. 2002....
How well does the Partin nomogram predict pathological stage after radical prostatectomy in a community based population? Results of the cancer of the prostate strategic urological research endeavorDavid F Penson
Section of Urology, Veterans Affairs Puget Sound Health Care System and Department of Urology, University of Washington, Seattle, Washington, USA
J Urol 167:1653-7; discussion 1657-8. 2002..We assessed the performance of the nomogram in the Cancer of the Prostate Strategic Urological Research Endeavor, a nationwide, community based observational disease registry of men with prostate cancer...
Overdiagnosis due to prostate-specific antigen screening: lessons from U.S. prostate cancer incidence trendsRuth Etzioni
Program in Biostatistics, Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
J Natl Cancer Inst 94:981-90. 2002..Overdiagnosis was defined as the detection of prostate cancer through PSA testing that otherwise would not have been diagnosed within the patient's lifetime...
Pathological guidelines for orthotopic urinary diversion in women with bladder cancer: a review of the literatureJohn P Stein
Department of Urology, University of Southern California, Norris Comprehensive Cancer Center, Los Angeles, California 90089, USA
J Urol 178:756-60. 2007..We reviewed the literature regarding the incidence of urethral involvement, the risk factors for urethral involvement and the incidence of urethral recurrence in women undergoing orthotopic urinary diversion for bladder cancer...
Is quality of life different for men with erectile dysfunction and prostate cancer compared to men with erectile dysfunction due to other causes? Results from the ExCEED data baseDavid F Penson
Section of Urology, VA Puget Sound Health Care System and Departmnent Urology, University of Washington, Seattle, USA
J Urol 169:1458-61. 2003..Lake Forest, Illinois) data base, which is a multicenter, observational disease registry of men with erectile dysfunction...
Quality of life after treatment for prostate cancerDavid F Penson
Department of Urology, David Geffen School of Medicine and School of Public Health, University of California, Los Angeles 66-121CHS, Box 951738, Los Angeles, CA 90095-1738, USA
Curr Urol Rep 4:185-95. 2003..Better information regarding the potential impact of prostate cancer treatment on quality of life will improve medical decision-making...
Race independently predicts prostate specific antigen testing frequency following a prostate carcinoma diagnosisSteven B Zeliadt
Fred Hutchinson Cancer Research Center, Seattle, Washington 98109-1024, USA
Cancer 98:496-503. 2003..Further research is needed to identify the reasons for the racial disparity in PSA surveillance and to design interventions to lessen these differences...
Validation of increasing prostate specific antigen as a predictor of prostate cancer death after treatment of localized prostate cancer with surgery or radiationPeter C Albertsen
University of Connecticut Health Center, Farmington, Connecticut 06030 3955, USA
J Urol 171:2221-5. 2004..This study documents patterns of PSA recurrence after surgery or radiation to treat localized prostate cancer and quantifies the extent to which an increasing PSA predicts death from prostate cancer...
Five-year outcomes after prostatectomy or radiotherapy for prostate cancer: the prostate cancer outcomes studyArnold L Potosky
Division of Cancer Control and Population Sciences, National Cancer Institute, EPN Rm 4005, 6130 Executive Blvd, MSC 7344, Bethesda, MD 20892 7344, USA
J Natl Cancer Inst 96:1358-67. 2004..We present treatment-specific quality-of-life outcomes for prostate cancer patients 5 years after initial diagnosis...
Combining longitudinal studies of PSALurdes Y T Inoue
University of Washington, Department of Biostatistics, F 600 Health Sciences Building, Campus Mail Stop 357232, Seattle, WA 98195, USA
Biostatistics 5:483-500. 2004....
Cross-sectional and longitudinal comparisons of health-related quality of life between patients with prostate carcinoma and matched controlsRichard M Hoffman
Medicine Service, New Mexico Veterans Affairs Health Care System, Albuquerque, NM 87108, USA
Cancer 101:2011-9. 2004..Prostate carcinoma and treatments affect health-related quality of life (HRQOL). The authors prospectively compared prostate and general HRQOL between prostate carcinoma cases and an age-matched and ethnicity-matched control group...
Why do men choose one treatment over another?: a review of patient decision making for localized prostate cancerSteven B Zeliadt
Public Health Sciences Division, Fred Hutchinson Cancer Center, Seattle, Washington 98109, USA
Cancer 106:1865-74. 2006..Considerable progress is needed in helping patients fully understand how to balance the complex issues surrounding prostate cancer treatment decision making...
PSA screening and elderly menEric A Singer
JAMA 297:949; author reply 949-50. 2007
Pharmacoeconomics of available treatment options for metastatic prostate cancerSteven B Zeliadt
Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA
Pharmacoeconomics 25:309-27. 2007..It is essential that we address the weaknesses in our understanding of the economic consequences of therapies for prostate cancer, and find ways to include economic information into the process of determining optimal therapy...
Prostate cancerDavid F Penson
Departments of Urology and Preventive Medicine, Keck School of Medicine, University of Southern California, 1441 Eastlake Avenue, Los Angeles, CA 90089, USA
J Urol 177:2020-9. 2007..We quantified the burden of prostate cancer in the United States by identifying trends in incidence, disease presentation, survival rates and use of health care resources, and by estimating the economic impact of the disease...
Symptoms and inflammation in chronic prostatitis/chronic pelvic pain syndromeJohn N Krieger
Department of Urology, School of Medicine, University of Washington, Seattle, Washington, USA
Urology 60:959-63. 2002....
Quality of life after therapy for localized prostate cancerDavid F Penson
Departments of Urology and Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA
Cancer J 13:318-26. 2007..Finally, I attempt to directly compare the quality-of-life effects of the various treatments to assist clinicians in advising patients with newly diagnosed localized prostate cancer...
Internet health resources and the cancer patientGeorge J Huang
Department of Urology, Keck School of Medicine, University of Southern California, Los Angeles, California 90089, USA
Cancer Invest 26:202-7. 2008....
Dietary patterns, supplement use, and the risk of symptomatic benign prostatic hyperplasia: results from the prostate cancer prevention trialAlan R Kristal
Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
Am J Epidemiol 167:925-34. 2008..A diet low in fat and red meat and high in protein and vegetables, as well as regular alcohol consumption, may reduce the risk of symptomatic BPH...
Impact of PSA screening on the incidence of advanced stage prostate cancer in the United States: a surveillance modeling approachRuth Etzioni
Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109 1024, USA
Med Decis Making 28:323-31. 2008..The objective was to quantify this link between PSA screening and the decline in distant stage incidence...
Invasive T1 bladder cancer: indications and rationale for radical cystectomyJohn P Stein
Department of Urology, University of Southern California Keck School of Medicine, Norris Comprehensive Cancer Center, Los Angeles, CA 90089, USA
BJU Int 102:270-5. 2008..This review provides a rationale for a radical cystectomy in patients with high-risk, invasive T1 bladder cancer...
Predictors of intravesical therapy for nonmuscle invasive bladder cancer: results from the surveillance, epidemiology and end results program 2003 patterns of care projectGeorge J Huang
Department of Urology, Keck School of Medicine, University of Southern California, Los Angeles, California, USA
J Urol 180:520-4; discussion 524. 2008..We examined patterns of intravesical therapy use in nonmuscle invasive bladder cancer in 2003 to determine whether disparities remained in the quality of cancer care...
Lifetime implications and cost-effectiveness of using finasteride to prevent prostate cancerSteven B Zeliadt
Fred Hutchinson Cancer Research Center, Seattle, Wash 98109, USA
Am J Med 118:850-7. 2005....
Radical cystectomy with extended lymphadenectomy: evaluating separate package versus en bloc submission for node positive bladder cancerJohn P Stein
Department of Urology, University of Southern California, Norris Comprehensive Cancer Center, Los Angeles, California 90089, USA
J Urol 177:876-81; discussion 881-2. 2007..We evaluated the clinical and pathological findings resulting from this modification...
Trends in treatment costs for localized prostate cancer: the healthy screenee effectSteven B Zeliadt
Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109 1024, USA
Med Care 45:154-9. 2007..We sought to obtain estimates of trends in initial treatment costs during the prostate-specific antigen (PSA) era that account for the changing patient case-mix associated with screening...
Long-term effects of finasteride on prostate specific antigen levels: results from the prostate cancer prevention trialRuth D Etzioni
Fred Hutchinson Cancer Research Center, Seattle, Washington 98109 1024, USA
J Urol 174:877-81. 2005..We estimated the long-term effects of finasteride on PSA in men with and without a prostate cancer diagnosis at the end of the study...
An update on randomized clinical trials in localized and locoregional prostate cancerDavid F Penson
Urology and Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90089, USA
Urol Oncol 23:280-8. 2005..Although there are numerous phase III studies ongoing in these areas, there are still large gaps in our understanding of the treatment of localized disease, and additional clinical trials are needed...
Laparoscopic urological oncology: here come the outcomes!David F Penson
J Urol 174:1174. 2005
Variations in prostate cancer patterns of care: is it the quality of care or the quality of the data?David F Penson
J Clin Oncol 23:7783-4. 2005
Prostate-specific antigen and free prostate-specific antigen in the early detection of prostate cancer: do combination tests improve detection?Ruth Etzioni
Program in Biostatistics, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, M2 B230, Seattle, WA 98109 1024, USA
Cancer Epidemiol Biomarkers Prev 13:1640-5. 2004..The combined use of free and total prostate-specific antigen (PSA) in early detection of prostate cancer has been controversial. This article systematically evaluates the discriminating capacity of a large number of combination tests...
The cost-effectiveness of combined androgen blockade with bicalutamide and luteinizing hormone releasing hormone agonist in men with metastatic prostate cancerDavid F Penson
Department of Urology and Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California 90089, USA
J Urol 174:547-52; discussion 552. 2005..The goal of this study was to assess the cost-effectiveness of CAB with bicalutamide and LH-RH agonist therapy to LH-RH agonist therapy alone...
Cigarette smoking and risk of prostate cancer in middle-aged menLora A Plaskon
Department of Urology, University of Washington, Seattle, USA
Cancer Epidemiol Biomarkers Prev 12:604-9. 2003..Given that smoking cessation seems to reduce these risks, results from this study have public health ramifications and suggest that prostate cancer should be added to the list of tumors for which cigarette smoking is a risk factor...
The economic burden of metastatic and prostate specific antigen progression in patients with prostate cancer: findings from a retrospective analysis of health plan dataDavid F Penson
Keck School of Medicine, University of Southern California, Los Angeles, California 90089, USA
J Urol 171:2250-4. 2004..We evaluated the economic burden of metastatic and prostate specific antigen (PSA) progression in patients with prostate cancer (CaP) using a cancer registry linked administrative database...
Health related quality of life in men with prostate cancerDavid F Penson
Section of Urology, VA Puget Sound Health Care System, Seattle, WA, USA
J Urol 169:1653-61. 2003..This information is of critical importance when counseling men with newly diagnosed prostate cancer regarding treatment choices and is also helpful in setting appropriate expectations for men with metastatic disease...
Laparoscopic partial nephrectomy and prostatectomy: weighing the costs and the benefitsDavid F Penson
J Urol 172:6-7. 2004
Longitudinal differences in disease specific quality of life in men with erectile dysfunction: results from the Exploratory Comprehensive Evaluation of Erectile Dysfunction studyDavid M Latini
Department of Urology and Urology Outcomes Research Group, Univeristy of California, San Francisco, USA
J Urol 169:1437-42. 2003....
Psychological impact of erectile dysfunction: validation of a new health related quality of life measure for patients with erectile dysfunctionDavid M Latini
Department of Urology and Urology Outcomes Research Group, University of California, San Francisco, USA
J Urol 168:2086-91. 2002....
Insulin-like growth factor-I, insulin-like growth factor binding protein-3 and risk of benign prostate hyperplasia in the prostate cancer prevention trialMarian L Neuhouser
Cancer Prevention Program, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
Prostate 68:1477-86. 2008....
