Research Topics
Species | Robert C PendletonSummaryAffiliation: University of Utah Country: USA Publications
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Detail Information
Publications
Design and rationale of the Utah obesity study. A study to assess morbidity following gastric bypass surgeryTed D Adams
University of Utah School of Medicine, Cardiovascular Genetics Research Program, Cardiology Division, Salt Lake City, UT 84108, USA
Contemp Clin Trials 26:534-51. 2005..This study is designed to assess the effectiveness of GBP in reducing morbidity and maintaining weight loss. A wide array of clinical tests and psycho-behavioral questionnaires are included as part of the study...
Venous thromboembolism prevention in the acutely ill medical patient: a review of the literature and focus on special patient populationsRobert Pendleton
Department of Internal Medicine, University of Utah, Salt Lake City, Utah 84132, USA
Am J Hematol 79:229-37. 2005....
Established venous thromboembolism therapies: heparin, low molecular weight heparins, and vitamin K antagonists, with a discussion of heparin-induced thrombocytopeniaRobert C Pendleton
Department of Medicine, University Healthcare Thrombosis Service, University of Utah, 50 North Medical Drive, Room 4B120, Salt Lake City, UT 84132, USA
Clin Chest Med 31:691-706. 2010..Further, in parallel with the evolution of VTE treatment, there have been remarkable advances in our understanding of heparin-induced thrombocytopenia, a prothrombotic complication of parenteral anticoagulant use...
Health benefits of gastric bypass surgery after 6 yearsTed D Adams
Department of Internal Medicine, University of Utah School of Medicine, 420 Chipeta Way, Room 1160, Salt Lake City, UT 84108, USA
JAMA 308:1122-31. 2012..Extreme obesity is associated with health and cardiovascular disease risks. Although gastric bypass surgery induces rapid weight loss and ameliorates many of these risks in the short term, long-term outcomes are uncertain...
Prospective comparison of three enoxaparin dosing regimens to achieve target anti-factor Xa levels in hospitalized, medically ill patients with extreme obesityAndrew Freeman
Department of Internal Medicine, University of Utah, Salt Lake City, UT, USA
Am J Hematol 87:740-3. 2012..5 mg/kg QDay is superior to FD and LD enoxaparin for the achievement of target anti-Factor Xa levels...
Current challenges in personalizing warfarin therapyGwendolyn A McMillin
Department of Pathology, University of Utah, ARUP Laboratories, UT, USA
Expert Rev Clin Pharmacol 4:349-62. 2011..Through further investigative work, allowing these personalized strategies to realize their full potential, warfarin may remain a preferred therapeutic oral anticoagulant for years to come...
A safe, effective, and easy to use warfarin initiation dosing nomogram for post-joint arthroplasty patientsRobert C Pendleton
Department of Medicine, General Internal Medicine, University Healthcare Thrombosis Service, University of Utah, Salt Lake City, Utah 84132, USA
J Arthroplasty 25:121-7. 2010....
Health outcomes of gastric bypass patients compared to nonsurgical, nonintervened severely obeseTed D Adams
Department of Internal Medicine, Cardiovascular Genetics Division, University of Utah, Salt Lake City, Utah, USA
Obesity (Silver Spring) 18:121-30. 2010....
Weight-based dosing of enoxaparin for VTE prophylaxis in morbidly obese, medically-Ill patientsMatthew T Rondina
Department of Internal Medicine, University of Utah, Salt Lake City, Utah 84132, USA
Thromb Res 125:220-3. 2010....
(18)F-FDG PET in the evaluation of acuity of deep vein thrombosisMatthew T Rondina
Division of General Internal Medicine, Department of Internal Medicine, University of Utah, Salt Lake City, UT 84132, USA
Clin Nucl Med 37:1139-45. 2012..F-FDG PET has been used for vascular disease, but its role in deep vein thrombosis (DVT) remains prospectively unexplored...
A pilot study utilizing whole body 18 F-FDG-PET/CT as a comprehensive screening strategy for occult malignancy in patients with unprovoked venous thromboembolismMatthew T Rondina
Division of General Internal Medicine, University of Utah, Salt Lake City, Utah 84132, USA
Thromb Res 129:22-7. 2012..In a pilot study, we prospectively investigated the use of FDG-PET/CT to screen for occult malignancy in 40 patients with unprovoked VTE...
Prevention of venous thromboembolism in obesityAndrew L Freeman
University of Utah Department of Internal Medicine, 50 North Medical Drive, Room 4B120, School of Medicine, Salt Lake City, UT 84132, USA
Expert Rev Cardiovasc Ther 8:1711-21. 2010..With the prevalence of morbid obesity continuing to rise, more high-quality clinical data are needed to better understand the pathobiology of VTE in obesity and provide effective, yet safe, prevention strategies...
Incidence and economic implications of heparin-induced thrombocytopenia in medical patients receiving prophylaxis for venous thromboembolismFreddy M Creekmore
College of Pharmacy, University of Utah, Salt Lake City, Utah 84112
Pharmacotherapy 26:1438-45. 2006....
Drug-induced thrombocytopenia for the hospitalist physician with a focus on heparin-induced thrombocytopeniaMatthew T Rondina
Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City, UT 84112, USA
Hosp Pract (1995) 38:19-28. 2010..Because patients with HIT have a high risk of thrombosis and bleeding is uncommon, the prompt initiation of an alternative anticoagulant (e.g., a direct thrombin inhibitor) is warranted in these patients...
Pharmacogenetic warfarin dose refinements remain significantly influenced by genetic factors after one week of therapyBenjamin D Horne
Cardiovascular Department, Intermountain Medical Center, Salt Lake City, Utah 84107, USA
Thromb Haemost 107:232-40. 2012..7 mg/week. In conclusion, a pharmacogenetic warfarin dose-refinement algorithm based on clinical, INR, and genetic factors can explain at least 69.1% of therapeutic warfarin dose variability after about one week of therapy...
Favorable changes in cardiac geometry and function following gastric bypass surgery: 2-year follow-up in the Utah obesity studyTheophilus Owan
Division of Cardiology, University of Utah School of Medicine, Salt Lake City, USA
J Am Coll Cardiol 57:732-9. 2011..The objective of this study was to test the hypothesis that gastric bypass surgery (GBS) would favorably impact cardiac remodeling and function...
Gene-based warfarin dosing compared with standard of care practices in an orthopedic surgery population: a prospective, parallel cohort studyGwendolyn A McMillin
University of Utah Health Sciences, Department of Internal Medicine, Salt Lake City, Utah, USA
Ther Drug Monit 32:338-45. 2010..Findings suggest alternative strategies for dosing based on the presence or absence of genetic variants is needed...
Hip fracture management for the hospital-based clinician: a review of the evidence and best practicesJason Hughson
Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City, UT 84132, USA
Hosp Pract (1995) 39:52-61. 2011....
Azathioprine-induced warfarin resistanceSara R Vazquez
UDepartment of Pharmacy Services, University Thrombosis Service, University of Utah, Salt Lake City, UT 84108, USA
Ann Pharmacother 42:1118-23. 2008..To describe a case of azathioprine-induced warfarin resistance, present a literature review on warfarin-azathioprine interactions, and provide recommendations on appropriate management of this clinically significant interaction...
Abdominal aortitis due to Streptococcus pneumoniae and Enterobacter aerogenes: a case report and reviewMatthew T Rondina
Department of Internal Medicine, University of Utah Health Sciences Center, Salt Lake City, UT 84132, USA
J Gen Intern Med 21:C1-3. 2006..Clinicians should maintain a high index of suspicion for infectious aortitis as the mortality, if only treated medically, approaches 100%...
Hospital-based clinical implications of the novel oral anticoagulant, dabigatran etexilate, in daily practiceRyan Wilcox
Department of Medicine, University of Utah Health Sciences Center, Salt Lake City, UT, USA
Hosp Pract (1995) 39:23-34. 2011..We also provide an approach to patients on dabigatran etexilate who are bleeding, have a suspected therapeutic failure, or require periprocedural management...
Periprocedural antithrombotic management: a review of the literature and practical approach for the hospitalist physicianRussell Vinik
Department of Internal Medicine, General Medicine Hospitalist Group, University of Utah, Salt Lake City, Utah 84132, USA
J Hosp Med 4:551-9. 2009..of oral anticoagulation? (3) Are there low thromboembolic risk populations who do not require periprocedural bridging? (4) How do you manage patients who must discontinue anti-coagulants but are at an increased thrombotic risk?..
A necessary detourRobert C Pendleton
Department of Internal Medicine, University of Utah Health Sciences Center, Salt Lake City, Utah, USA
Am J Med 119:651-3. 2006
The treatment of venous thromboembolism in special populationsMatthew T Rondina
The University of Utah Health Sciences Center, Department of Internal Medicine, Salt Lake City, UT 84132, USA
Thromb Res 119:391-402. 2007..This review summarizes the current data for these special patient populations with venous thromboembolism and provides our recommendations for management...
Pulmonary embolism with unexpected echocardiogram findingsKencee K Graves
University of Utah School of Medicine, Salt Lake City, UT 84132, USA
Hosp Pract (1995) 38:84-8. 2010..When clinicians identify multiple clinical findings, Occam's razor suggests that these multiple findings are most likely related...
Physician alerts to prevent symptomatic venous thromboembolism in hospitalized patientsGregory Piazza
Cardiovascular Division, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
Circulation 119:2196-201. 2009....
Safety and efficacy of an insulin infusion protocol designed for the non-intensive care settingRussell Vinik
Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City, Utah 84132, USA
Endocr Pract 15:682-8. 2009..To determine whether glycemic control can be safely achieved with use of a simplified insulin infusion protocol in hospitalized patients who are not in the intensive care unit (ICU)...
Left ventricular hypertrophy in severe obesity: interactions among blood pressure, nocturnal hypoxemia, and body massErick Avelar
Division of Cardiology, University of Utah School of Medicine, Salt Lake City, USA
Hypertension 49:34-9. 2007..The effects of increased blood pressure seem to amplify those of sleep apnea and more severe obesity...
Venous thromboembolism prophylaxis in medically ill patients and the development of strategies to improve prophylaxis ratesJason M Stinnett
Mountain States Tumor Institute, Boise, Idaho, USA
Am J Hematol 78:167-72. 2005..Implementation of strategies to improve prophylaxis rates, including educational sessions and risk stratification guidelines, can be successful and improve identification and prophylaxis of this population...
Health-related quality of life in patients seeking gastric bypass surgery vs non-treatment-seeking controlsRonette L Kolotkin
Obesity and Quality of Life Consulting, Durham, NC 27707, USA
Obes Surg 13:371-7. 2003....
