Francisco J Pelegri

Summary

Affiliation: University of Wisconsin
Country: USA

Publications

  1. pmc The maternal-effect gene cellular island encodes aurora B kinase and is essential for furrow formation in the early zebrafish embryo
    Taijiro Yabe
    Laboratory of Genetics, University of Wisconsin Madison, Madison, WI, USA
    PLoS Genet 5:e1000518. 2009
  2. pmc The chromosomal passenger protein birc5b organizes microfilaments and germ plasm in the zebrafish embryo
    Sreelaja Nair
    Laboratory of Genetics, University of Wisconsin Madison, Madison, Wisconsin, United States of America
    PLoS Genet 9:e1003448. 2013
  3. pmc Wnt4 is not sufficient to induce lobuloalveolar mammary development
    Young Chul Kim
    McArdle Laboratory for Cancer Research, School of Medicine and Public Health, University of Wisconsin Madison, Wisconsin, USA
    BMC Dev Biol 9:55. 2009
  4. ncbi request reprint Maternal factors in zebrafish development
    Francisco Pelegri
    Laboratory of Genetics, University of Wisconsin, Madison, Wisconsin, USA
    Dev Dyn 228:535-54. 2003
  5. ncbi request reprint Identification of recessive maternal-effect mutations in the zebrafish using a gynogenesis-based method
    Francisco Pelegri
    Max Plank Institut für Entwicklungsbiologie, Abteilung Genetik, Tubingen, Germany
    Dev Dyn 231:324-35. 2004
  6. ncbi request reprint Analysis of axis induction mutant embryos reveals morphogenetic events associated with zebrafish yolk extension formation
    Jamie Lyman Gingerich
    Laboratory of Genetics, University of Wisconsin Madison, Madison, Wisconsin, USA
    Dev Dyn 235:2749-60. 2006
  7. ncbi request reprint The maternal-effect gene futile cycle is essential for pronuclear congression and mitotic spindle assembly in the zebrafish zygote
    Marcus P S Dekens
    Max Planck Institut fur Entwicklungsbiologie, Abteilung Genetik, Spemannstrasse 35, 72076 Tubingen, Germany
    Development 130:3907-16. 2003
  8. ncbi request reprint A role for non-muscle myosin II function in furrow maturation in the early zebrafish embryo
    Lance E Urven
    Laboratory of Genetics, University of Wisconsin Madison, WI 53706, USA
    J Cell Sci 119:4342-52. 2006
  9. pmc Zebrafish chordin-like and chordin are functionally redundant in regulating patterning of the dorsoventral axis
    Amanda M Branam
    Molecular and Cellular Pharmacology Program, University of Wisconsin, 1300 University Ave, Madison, WI 53706, USA
    Dev Biol 341:444-58. 2010
  10. doi request reprint Practical approaches for implementing forward genetic strategies in zebrafish
    Sreelaja Nair
    Laboratory of Genetics, University of Wisconsin Madison, Madison, WI, USA
    Methods Mol Biol 770:185-209. 2011

Research Grants

Collaborators

Detail Information

Publications18

  1. pmc The maternal-effect gene cellular island encodes aurora B kinase and is essential for furrow formation in the early zebrafish embryo
    Taijiro Yabe
    Laboratory of Genetics, University of Wisconsin Madison, Madison, WI, USA
    PLoS Genet 5:e1000518. 2009
    ..In accordance with the requirement for cei/aurB in furrow induction in the early cleavage embryo, germ plasm recruitment to the forming furrow is also affected in embryos lacking normal cei/aurB function...
  2. pmc The chromosomal passenger protein birc5b organizes microfilaments and germ plasm in the zebrafish embryo
    Sreelaja Nair
    Laboratory of Genetics, University of Wisconsin Madison, Madison, Wisconsin, United States of America
    PLoS Genet 9:e1003448. 2013
    ..In addition to the known mitotic function of CPC components, our analyses reveal a non-canonical role for an evolutionarily conserved CPC protein in microfilament reorganization and germ plasm aggregation...
  3. pmc Wnt4 is not sufficient to induce lobuloalveolar mammary development
    Young Chul Kim
    McArdle Laboratory for Cancer Research, School of Medicine and Public Health, University of Wisconsin Madison, Wisconsin, USA
    BMC Dev Biol 9:55. 2009
    ..Therefore, we generated conditional transgenic mice to test whether Wnt4 can stimulate mammary epithelial cell growth...
  4. ncbi request reprint Maternal factors in zebrafish development
    Francisco Pelegri
    Laboratory of Genetics, University of Wisconsin, Madison, Wisconsin, USA
    Dev Dyn 228:535-54. 2003
    ....
  5. ncbi request reprint Identification of recessive maternal-effect mutations in the zebrafish using a gynogenesis-based method
    Francisco Pelegri
    Max Plank Institut für Entwicklungsbiologie, Abteilung Genetik, Tubingen, Germany
    Dev Dyn 231:324-35. 2004
    ..The sample of mutations that we have identified reflects the diversity of maternally driven functions in early development and underscores the importance of maternal factors in this process...
  6. ncbi request reprint Analysis of axis induction mutant embryos reveals morphogenetic events associated with zebrafish yolk extension formation
    Jamie Lyman Gingerich
    Laboratory of Genetics, University of Wisconsin Madison, Madison, Wisconsin, USA
    Dev Dyn 235:2749-60. 2006
    ....
  7. ncbi request reprint The maternal-effect gene futile cycle is essential for pronuclear congression and mitotic spindle assembly in the zebrafish zygote
    Marcus P S Dekens
    Max Planck Institut fur Entwicklungsbiologie, Abteilung Genetik, Spemannstrasse 35, 72076 Tubingen, Germany
    Development 130:3907-16. 2003
    ..Therefore, we propose that in mitotic spindle assembly chromosome-dependent microtubule nucleation is essential for the coupling of nuclear and cell division...
  8. ncbi request reprint A role for non-muscle myosin II function in furrow maturation in the early zebrafish embryo
    Lance E Urven
    Laboratory of Genetics, University of Wisconsin Madison, WI 53706, USA
    J Cell Sci 119:4342-52. 2006
    ..Our studies support a role for myosin function in furrow maturation that is independent of furrow ingression and which is essential for the recruitment of furrow components and the remodeling of the cytoskeleton during cytokinesis...
  9. pmc Zebrafish chordin-like and chordin are functionally redundant in regulating patterning of the dorsoventral axis
    Amanda M Branam
    Molecular and Cellular Pharmacology Program, University of Wisconsin, 1300 University Ave, Madison, WI 53706, USA
    Dev Biol 341:444-58. 2010
    ..Loss-of-function experiments demonstrate that Chl serves as a BMP antagonist with functions that overlap and are redundant with those of Chd in forming the dorsoventral axis...
  10. doi request reprint Practical approaches for implementing forward genetic strategies in zebrafish
    Sreelaja Nair
    Laboratory of Genetics, University of Wisconsin Madison, Madison, WI, USA
    Methods Mol Biol 770:185-209. 2011
    ..2). Additional stand-alone procedures are provided in Section 3.3, which are also required for the execution of the experiments discussed in its preceding sections...
  11. ncbi request reprint Bone morphogenetic protein 1 prodomain specifically binds and regulates signaling by bone morphogenetic proteins 2 and 4
    Reema Jasuja
    Program in Molecular and Cellular Pharmacology, University of Wisconsin, Madison, Wisconsin 53706, USA
    J Biol Chem 282:9053-62. 2007
    ..It is further demonstrated that the BMP1 prodomain is capable of modulating signaling by BMPs 2 and 4 in vitro and in vivo, and that endogenous BMP1 prodomain-BMP4 complexes exist in cell culture media and in tissues...
  12. ncbi request reprint Separate pathways of RNA recruitment lead to the compartmentalization of the zebrafish germ plasm
    Elizabeth V Theusch
    Laboratory of Genetics, University of Wisconsin Madison, 425 G Henry Mall, Madison, WI 53706, USA
    Dev Biol 292:129-41. 2006
    ..Our observations suggest that separate pathways of RNA recruitment facilitate the compartmentalization of the zebrafish germ plasm...
  13. pmc The zebrafish maternal-effect gene cellular atoll encodes the centriolar component sas-6 and defects in its paternal function promote whole genome duplication
    Taijiro Yabe
    Laboratory of Genetics, University of Wisconsin, Madison, USA
    Dev Biol 312:44-60. 2007
    ....
  14. doi request reprint Vertebrate maternal-effect genes: Insights into fertilization, early cleavage divisions, and germ cell determinant localization from studies in the zebrafish
    Robin E Lindeman
    Laboratory of Genetics, University of Wisconsin Madison, Madison, Wisconsin, USA
    Mol Reprod Dev 77:299-313. 2010
    ....
  15. ncbi request reprint bmp1 and mini fin are functionally redundant in regulating formation of the zebrafish dorsoventral axis
    Reema Jasuja
    Molecular and Cellular Pharmacology Program, University of Wisconsin, 1300 University Avenue, Madison, WI 53706, USA
    Mech Dev 123:548-58. 2006
    ..We conclude that bmp1 and mfn gene products functionally overlap and are together responsible for a key portion of the Chordin processing activity necessary to formation of the zebrafish dorsoventral axis...
  16. ncbi request reprint hecate, a zebrafish maternal effect gene, affects dorsal organizer induction and intracellular calcium transient frequency
    Jamie Lyman Gingerich
    Laboratory of Genetics, 425 G Henry Mall, University of Wisconsin Madison, Madison, WI 53706, USA
    Dev Biol 286:427-39. 2005
    ....
  17. pmc Characterization of the six zebrafish clade B fibrillar procollagen genes, with evidence for evolutionarily conserved alternative splicing within the pro-alpha1(V) C-propeptide
    Guy G Hoffman
    Department of Pathology and Laboratory Medicine, University of Wisconsin, Madison, WI 53706, USA
    Matrix Biol 29:261-75. 2010
    ..Data presented herein provide insights into the nature of clade B procollagen chains and should facilitate their study in the zebrafish model system...
  18. ncbi request reprint Genetic screens for maternal-effect mutations
    Francisco Pelegri
    University of Wisconsin Madison, Laboratory of Genetics, Madison, Wisconsin 53706, USA
    Methods Cell Biol 77:21-51. 2004

Research Grants9

  1. Cytokinesis and RNA segregation in zebrafish development
    Francisco Pelegri; Fiscal Year: 2006
    ..abstract_text> ..
  2. Cytokinesis and RNA segregation in zebrafish development
    Francisco Pelegri; Fiscal Year: 2002
    ..abstract_text> ..
  3. Cytokinesis and RNA segregation in zebrafish development
    Francisco Pelegri; Fiscal Year: 2003
    ..abstract_text> ..
  4. Cytokinesis and RNA segregation in zebrafish development
    Francisco Pelegri; Fiscal Year: 2004
    ..abstract_text> ..
  5. Cytokinesis and RNA segregation in zebrafish development
    Francisco Pelegri; Fiscal Year: 2005
    ..abstract_text> ..
  6. Cytokinesis and RNA segregation in zebrafish development
    Francisco Pelegri; Fiscal Year: 2007
    ..abstract_text> ..
  7. Cytokinesis and RNA segregation in zebrafish development
    Francisco Pelegri; Fiscal Year: 2009
    ..Knowledge acquired through these studies will lead to progress in therapies that alleviate health problems related to reproductive biology, cancer, and stem cell and tissue development. ..
  8. Cytokinesis and RNA segregation in zebrafish development
    Francisco J Pelegri; Fiscal Year: 2010
    ..Knowledge acquired through these studies will lead to progress in therapies that alleviate health problems related to reproductive biology, cancer, and stem cell and tissue development. ..