Research Topics
Genomes and Genes | Francisco J PelegriSummaryAffiliation: University of Wisconsin Country: USA Publications
Research Grants
| Collaborators
|
Detail Information
Publications
Wnt4 is not sufficient to induce lobuloalveolar mammary developmentYoung Chul Kim
McArdle Laboratory for Cancer Research, School of Medicine and Public Health, University of Wisconsin Madison, Wisconsin, USA
BMC Dev Biol 9:55. 2009..Therefore, we generated conditional transgenic mice to test whether Wnt4 can stimulate mammary epithelial cell growth...
Maternal factors in zebrafish developmentFrancisco Pelegri
Laboratory of Genetics, University of Wisconsin, Madison, Wisconsin, USA
Dev Dyn 228:535-54. 2003....- Identification of recessive maternal-effect mutations in the zebrafish using a gynogenesis-based methodFrancisco Pelegri
Max Plank Institut für Entwicklungsbiologie, Abteilung Genetik, Tubingen, Germany
Dev Dyn 231:324-35. 2004..The sample of mutations that we have identified reflects the diversity of maternally driven functions in early development and underscores the importance of maternal factors in this process... - Analysis of axis induction mutant embryos reveals morphogenetic events associated with zebrafish yolk extension formationJamie Lyman Gingerich
Laboratory of Genetics, University of Wisconsin Madison, Madison, Wisconsin, USA
Dev Dyn 235:2749-60. 2006.... - The maternal-effect gene futile cycle is essential for pronuclear congression and mitotic spindle assembly in the zebrafish zygoteMarcus P S Dekens
Max Planck Institut fur Entwicklungsbiologie, Abteilung Genetik, Spemannstrasse 35, 72076 Tubingen, Germany
Development 130:3907-16. 2003..Therefore, we propose that in mitotic spindle assembly chromosome-dependent microtubule nucleation is essential for the coupling of nuclear and cell division... - The maternal-effect gene cellular island encodes aurora B kinase and is essential for furrow formation in the early zebrafish embryoTaijiro Yabe
Laboratory of Genetics, University of Wisconsin Madison, Madison, WI, USA
PLoS Genet 5:e1000518. 2009..In accordance with the requirement for cei/aurB in furrow induction in the early cleavage embryo, germ plasm recruitment to the forming furrow is also affected in embryos lacking normal cei/aurB function... - Zebrafish chordin-like and chordin are functionally redundant in regulating patterning of the dorsoventral axisAmanda M Branam
Molecular and Cellular Pharmacology Program, University of Wisconsin, 1300 University Ave, Madison, WI 53706, USA
Dev Biol 341:444-58. 2010..Loss-of-function experiments demonstrate that Chl serves as a BMP antagonist with functions that overlap and are redundant with those of Chd in forming the dorsoventral axis... - A role for non-muscle myosin II function in furrow maturation in the early zebrafish embryoLance E Urven
Laboratory of Genetics, University of Wisconsin Madison, WI 53706, USA
J Cell Sci 119:4342-52. 2006..Our studies support a role for myosin function in furrow maturation that is independent of furrow ingression and which is essential for the recruitment of furrow components and the remodeling of the cytoskeleton during cytokinesis... - Bone morphogenetic protein 1 prodomain specifically binds and regulates signaling by bone morphogenetic proteins 2 and 4Reema Jasuja
Program in Molecular and Cellular Pharmacology, University of Wisconsin, Madison, Wisconsin 53706, USA
J Biol Chem 282:9053-62. 2007..It is further demonstrated that the BMP1 prodomain is capable of modulating signaling by BMPs 2 and 4 in vitro and in vivo, and that endogenous BMP1 prodomain-BMP4 complexes exist in cell culture media and in tissues... - The zebrafish maternal-effect gene cellular atoll encodes the centriolar component sas-6 and defects in its paternal function promote whole genome duplicationTaijiro Yabe
Laboratory of Genetics, University of Wisconsin, Madison, USA
Dev Biol 312:44-60. 2007.... - Separate pathways of RNA recruitment lead to the compartmentalization of the zebrafish germ plasmElizabeth V Theusch
Laboratory of Genetics, University of Wisconsin Madison, 425 G Henry Mall, Madison, WI 53706, USA
Dev Biol 292:129-41. 2006..Our observations suggest that separate pathways of RNA recruitment facilitate the compartmentalization of the zebrafish germ plasm... 
Vertebrate maternal-effect genes: Insights into fertilization, early cleavage divisions, and germ cell determinant localization from studies in the zebrafishRobin E Lindeman
Laboratory of Genetics, University of Wisconsin Madison, Madison, Wisconsin, USA
Mol Reprod Dev 77:299-313. 2010....- Practical approaches for implementing forward genetic strategies in zebrafishSreelaja Nair
Laboratory of Genetics, University of Wisconsin Madison, Madison, WI, USA
Methods Mol Biol 770:185-209. 2011..2). Additional stand-alone procedures are provided in Section 3.3, which are also required for the execution of the experiments discussed in its preceding sections... - bmp1 and mini fin are functionally redundant in regulating formation of the zebrafish dorsoventral axisReema Jasuja
Molecular and Cellular Pharmacology Program, University of Wisconsin, 1300 University Avenue, Madison, WI 53706, USA
Mech Dev 123:548-58. 2006..We conclude that bmp1 and mfn gene products functionally overlap and are together responsible for a key portion of the Chordin processing activity necessary to formation of the zebrafish dorsoventral axis... - hecate, a zebrafish maternal effect gene, affects dorsal organizer induction and intracellular calcium transient frequencyJamie Lyman Gingerich
Laboratory of Genetics, 425 G Henry Mall, University of Wisconsin Madison, Madison, WI 53706, USA
Dev Biol 286:427-39. 2005.... - Characterization of the six zebrafish clade B fibrillar procollagen genes, with evidence for evolutionarily conserved alternative splicing within the pro-alpha1(V) C-propeptideGuy G Hoffman
Department of Pathology and Laboratory Medicine, University of Wisconsin, Madison, WI 53706, USA
Matrix Biol 29:261-75. 2010..Data presented herein provide insights into the nature of clade B procollagen chains and should facilitate their study in the zebrafish model system... - Genetic screens for maternal-effect mutationsFrancisco Pelegri
University of Wisconsin-Madison, Laboratory of Genetics, Madison, Wisconsin 53706, USA
Methods Cell Biol 77:21-51. 2004
Research Grants
- Cytokinesis and RNA segregation in zebrafish developmentFrancisco Pelegri; Fiscal Year: 2006..abstract_text> ..
- Cytokinesis and RNA segregation in zebrafish developmentFrancisco Pelegri; Fiscal Year: 2007..abstract_text> ..
- Cytokinesis and RNA segregation in zebrafish developmentFrancisco J Pelegri; Fiscal Year: 2010..Knowledge acquired through these studies will lead to progress in therapies that alleviate health problems related to reproductive biology, cancer, and stem cell and tissue development. ..