Research Topics
| Jeremy L PeirceSummaryAffiliation: University of Tennessee Country: USA Publications
| Collaborators
|
Detail Information
Publications
An integrative genomics strategy for systematic characterization of genetic loci modulating phenotypesLei Bao
Department of Molecular Sciences, University of Tennessee Health Science Center, Memphis, TN 38163, USA
Hum Mol Genet 16:1381-90. 2007..This strategy integrates gene-phenotype relations from decades of experimental mutagenesis studies and new genomic resources to provide an approach to rapidly expand knowledge on genetic loci modulating phenotypes...
A simple method for combining genetic mapping data from multiple crosses and experimental designsJeremy L Peirce
Center for Neuroscience, Department of Anatomy and Neurobiology, University of Tennessee Health Science Center, Memphis, Tennessee, United States of America
PLoS ONE 2:e1036. 2007..Many phenotypes are now associated with enough mapping data that meta-analysis could help refine locations of known QTLs and detect many novel QTLs...- Genome Reshuffling for Advanced Intercross Permutation (GRAIP): simulation and permutation for advanced intercross population analysisJeremy L Peirce
Center for Neuroscience, Department of Anatomy and Neurobiology, University of Tennessee Health Science Center, Memphis, Tennessee, United States of America
PLoS ONE 3:e1977. 2008..The critical problem with naïve mapping approaches in AIL populations is that the individual is not an exchangeable unit... - Combining gene expression QTL mapping and phenotypic spectrum analysis to uncover gene regulatory relationshipsLei Bao
Department of Molecular Sciences, University of Tennessee Health Science Center, 858 Madison Avenue, Memphis, TN 38163, USA
Mamm Genome 17:575-83. 2006..Our results show that the combination of gene eQTL mapping and phenotypic spectrum analysis may provide a valuable approach to uncovering gene regulatory relations underlying mammalian phenotypes... - How replicable are mRNA expression QTL?Jeremy L Peirce
Center for Neuroscience, Department of Anatomy and Neurobiology, University of Tennessee Health Science Center, Memphis, TN 38163, USA
Mamm Genome 17:643-56. 2006..Finally, we note that while trans-acting QTL do not replicate well between data sets in general, at least one cluster of trans-acting QTL on distal Chr 1 is notably preserved between data sets... - Genetic analysis of barrel field size in the first somatosensory area (SI) in inbred and recombinant inbred strains of miceCheng X Li
Department of Anatomy and Neurobiology, College of Medicine, University of Tennessee Health Sciences Center, Memphis, TN 38163, USA
Somatosens Mot Res 22:141-50. 2005.... - A new set of BXD recombinant inbred lines from advanced intercross populations in miceJeremy L Peirce
Center for Neuroscience, Department of Anatomy and Neurobiology, University of Tennessee Health Science Center, 855 Monroe Avenue, Memphis, Tennessee 38163, USA
BMC Genet 5:7. 2004..elegans, and Drosophila, mouse RI panels typically consist of fewer than 30 lines. This is a severe constraint on the power and precision of mapping efforts and greatly hampers analysis of epistatic interactions... - Using gene expression databases for classical trait QTL candidate gene discovery in the BXD recombinant inbred genetic reference population: mouse forebrain weightLu Lu
Jiangsu Key Laboratory of Neuroregeneration, Nantong University, PR China
BMC Genomics 9:444. 2008..We also required verification of mRNA abundance by an independent method, and finally we required either differences in protein levels or confirmed DNA sequence differences... - The nature and identification of quantitative trait loci: a community's viewOduola Abiola
Nat Rev Genet 4:911-6. 2003..Quantitative trait loci (QTLs) can be identified in several ways, but is there a definitive test of whether a candidate locus actually corresponds to a specific QTL?..