Joel A Pedersen

Summary

Affiliation: University of Wisconsin
Country: USA

Publications

  1. ncbi request reprint Human pharmaceuticals, hormones, and personal care product ingredients in runoff from agricultural fields irrigated with treated wastewater
    Joel A Pedersen
    Molecular and Environmental Toxicology Center and Department of Soil Science, University of Wisconsin, Madison, Wisconsin 53706, USA
    J Agric Food Chem 53:1625-32. 2005
  2. ncbi request reprint Xenobiotic organic compounds in runoff from fields irrigated with treated wastewater
    Joel A Pedersen
    Environmental Science and Engineering Program, University of California Los Angeles, Charles E Young Drive South, CHS 46 081, 90095 1772, USA
    J Agric Food Chem 51:1360-72. 2003
  3. ncbi request reprint Organophosphorus insecticides in agricultural and residential runoff: field observations and implications for total maximum daily load development
    Joel A Pedersen
    Environmental Science and Engineering Program, University of California, Los Angeles, California 90095, USA
    Environ Sci Technol 40:2120-7. 2006
  4. pmc Oral transmissibility of prion disease is enhanced by binding to soil particles
    Christopher J Johnson
    Program in Cellular and Molecular Biology, University of Wisconsin Madison, Madison, Wisconsin, United States of America
    PLoS Pathog 3:e93. 2007
  5. doi request reprint Pathogenic prion protein is degraded by a manganese oxide mineral found in soils
    Fabio Russo
    Department of Soil Science and Molecular and Environmental Toxicology Center, University of Wisconsin, Madison, WI, USA
    J Gen Virol 90:275-80. 2009
  6. doi request reprint Influence of humic acid on titanium dioxide nanoparticle toxicity to developing zebrafish
    Sarah P Yang
    Molecular and Environmental Toxicology Center, University of Wisconsin, Madison, Wisconsin 53706, USA
    Environ Sci Technol 47:4718-25. 2013
  7. pmc Toxicity of oxidatively degraded quantum dots to developing zebrafish (Danio rerio)
    Paige N Wiecinski
    Molecular and Environmental Toxicology Center, University of Wisconsin, Madison, Wisconsin 53706, USA
    Environ Sci Technol 47:9132-9. 2013
  8. pmc Meat and bone meal and mineral feed additives may increase the risk of oral prion disease transmission
    Christopher J Johnson
    Prion Research Laboratory, USGS National Wildlife Health Center, Madison, Wisconsin, USA
    J Toxicol Environ Health A 74:161-6. 2011
  9. pmc Persistence of pathogenic prion protein during simulated wastewater treatment processes
    Glen T Hinckley
    Department of Civil and Environmental Engineering, University of Wisconsin, Madison, Wisconsin 53706, USA
    Environ Sci Technol 42:5254-9. 2008
  10. pmc Transport of the pathogenic prion protein through soils
    Kurt H Jacobson
    Civil and Environmental Engineering, Univ of Wisconsin, Madison, WI 53706, USA
    J Environ Qual 39:1145-52. 2010

Research Grants

  1. Impact of Microparticles on Oral TSE Infections
    Joel A Pedersen; Fiscal Year: 2010

Collaborators

Detail Information

Publications41

  1. ncbi request reprint Human pharmaceuticals, hormones, and personal care product ingredients in runoff from agricultural fields irrigated with treated wastewater
    Joel A Pedersen
    Molecular and Environmental Toxicology Center and Department of Soil Science, University of Wisconsin, Madison, Wisconsin 53706, USA
    J Agric Food Chem 53:1625-32. 2005
    ..None of these compounds were detected by broad-spectrum analysis in samples from the same fields during runoff-producing rain events...
  2. ncbi request reprint Xenobiotic organic compounds in runoff from fields irrigated with treated wastewater
    Joel A Pedersen
    Environmental Science and Engineering Program, University of California Los Angeles, Charles E Young Drive South, CHS 46 081, 90095 1772, USA
    J Agric Food Chem 51:1360-72. 2003
    ..Agricultural runoff also represented a source of allochthonous natural organic matter to the stream system...
  3. ncbi request reprint Organophosphorus insecticides in agricultural and residential runoff: field observations and implications for total maximum daily load development
    Joel A Pedersen
    Environmental Science and Engineering Program, University of California, Los Angeles, California 90095, USA
    Environ Sci Technol 40:2120-7. 2006
    ..A relative potency factor approach is introduced to permit evaluation of organophosphorus insecticides on a common toxicological basis and allow development of TMDLs and pollutant control strategies for these compounds as a class...
  4. pmc Oral transmissibility of prion disease is enhanced by binding to soil particles
    Christopher J Johnson
    Program in Cellular and Molecular Biology, University of Wisconsin Madison, Madison, Wisconsin, United States of America
    PLoS Pathog 3:e93. 2007
    ..Association of prions with inorganic microparticles represents a novel means by which their oral transmission is enhanced relative to unbound agent...
  5. doi request reprint Pathogenic prion protein is degraded by a manganese oxide mineral found in soils
    Fabio Russo
    Department of Soil Science and Molecular and Environmental Toxicology Center, University of Wisconsin, Madison, WI, USA
    J Gen Virol 90:275-80. 2009
    ..Exposure to 5.6 mg MnO(2) ml(-1) (PrP(TSE) : MnO(2)=1 : 110) decreased PrP(TSE) levels by > or = 4 orders of magnitude. Manganese oxides may contribute to prion degradation in soil environments rich in these minerals...
  6. doi request reprint Influence of humic acid on titanium dioxide nanoparticle toxicity to developing zebrafish
    Sarah P Yang
    Molecular and Environmental Toxicology Center, University of Wisconsin, Madison, Wisconsin 53706, USA
    Environ Sci Technol 47:4718-25. 2013
    ..This study demonstrates the importance of considering environmental factors (i.e., exposure to sunlight, adsorption of DOM) when assessing the potential risks posed by engineered nanomaterials in the environment...
  7. pmc Toxicity of oxidatively degraded quantum dots to developing zebrafish (Danio rerio)
    Paige N Wiecinski
    Molecular and Environmental Toxicology Center, University of Wisconsin, Madison, Wisconsin 53706, USA
    Environ Sci Technol 47:9132-9. 2013
    ..Our findings highlight the need to examine the toxicity of eNPs after they have undergone environmental weathering processes. ..
  8. pmc Meat and bone meal and mineral feed additives may increase the risk of oral prion disease transmission
    Christopher J Johnson
    Prion Research Laboratory, USGS National Wildlife Health Center, Madison, Wisconsin, USA
    J Toxicol Environ Health A 74:161-6. 2011
    ..Our data suggest that in feed or other prion-contaminated substances consumed by animals or, potentially, humans, the addition of MBM or the presence of microparticles could heighten risks of prion disease acquisition...
  9. pmc Persistence of pathogenic prion protein during simulated wastewater treatment processes
    Glen T Hinckley
    Department of Civil and Environmental Engineering, University of Wisconsin, Madison, Wisconsin 53706, USA
    Environ Sci Technol 42:5254-9. 2008
    ..Our results suggest that if prions were to enter municipal wastewater treatment systems, most would partition to activated sludge solids, survive mesophilic anaerobic digestion, and be present in treated biosolids...
  10. pmc Transport of the pathogenic prion protein through soils
    Kurt H Jacobson
    Civil and Environmental Engineering, Univ of Wisconsin, Madison, WI 53706, USA
    J Environ Qual 39:1145-52. 2010
    ..In the case of infected carcasses deposited on the land surface, this may result in local sources of infectivity to other animals...
  11. ncbi request reprint Human pharmaceuticals, antioxidants, and plasticizers in wastewater treatment plant and water reclamation plant effluents
    Mary A Soliman
    Department of Environmental Health Sciences, University of California, Los Angeles, USA
    Water Environ Res 79:156-67. 2007
    ..Nontarget compounds in recharged groundwater appeared to be attenuated with increased residence time in the aquifer...
  12. pmc Attachment of pathogenic prion protein to model oxide surfaces
    Kurt H Jacobson
    Department of Civil and Environmental Engineering, University of Wisconsin, Madison, Wisconsin 53706, United States
    Environ Sci Technol 47:6925-34. 2013
    ..Our findings suggest that prions would tend to associate with positively charged mineral surfaces in soils (e.g., iron and aluminum oxides). ..
  13. doi request reprint TiO2 nanoparticle exposure and illumination during zebrafish development: mortality at parts per billion concentrations
    Ofek Bar-Ilan
    Pharmaceutical Sciences Division, School of Pharmacy, University of Wisconsin, Madison, Wisconsin 53706, USA
    Environ Sci Technol 47:4726-33. 2013
    ..Zebrafish take up TiO2NPs from the aqueous environment even at low ng/mL concentrations, and these particles when illuminated in the violet-near UV range produce cumulative toxicity...
  14. ncbi request reprint Interaction of the macrolide antimicrobial clarithromycin with dissolved humic acid
    Samuel D Sibley
    Environmental Chemistry and Technology Program, and Department of Soil Science, University of Wisconsin, Madison, Wisconsin 53706, USA
    Environ Sci Technol 42:422-8. 2008
    ..CLA-ESHA association constants were similar in magnitude (10(3.9)-10(4.6) to those of many nonpolar organic contaminants, and macroscopic binding data were consistent with cation exchange dominating CLA+ -ESHA association...
  15. pmc Occurrence of tetracycline resistance genes in aquaculture facilities with varying use of oxytetracycline
    Erin E Seyfried
    Department of Civil and Environmental Engineering, University of Wisconsin at Madison, 3204 Engineering Hall, 1415 Engineering Drive, Madison, WI 53706, USA
    Microb Ecol 59:799-807. 2010
    ..To our knowledge, this is the first study to use genotypic and cultivation-independent methods to examine tet(R) gene occurrence associated with OTC use in aquaculture...
  16. pmc Transport of the pathogenic prion protein through landfill materials
    Kurt H Jacobson
    Department of Civil and Environmental Engineering, University of Wisconsin, Madison, Wisconsin 53706, USA
    Environ Sci Technol 43:2022-8. 2009
    ..g., encasement in fine-grained soil) are used...
  17. pmc Detection of known and novel adenoviruses in cattle wastes via broad-spectrum primers
    Samuel D Sibley
    Environmental Chemistry and Technology Program, University of Wisconsin, Madison, WI 53706 1299, USA
    Appl Environ Microbiol 77:5001-8. 2011
    ..To our knowledge, this is the first study to report natural BAdV excretion in urine, BAdV detection in groundwater, and recombination in AdV of livestock origin...
  18. doi request reprint Sorption of sulfonamide antimicrobial agents to humic acid-clay complexes
    Juan Gao
    Dep of Soil Science, Univ of Wisconsin, Madison, WI 53706, USA
    J Environ Qual 39:228-35. 2010
    ....
  19. pmc Low copper and high manganese levels in prion protein plaques
    Christopher J Johnson
    USGS National Wildlife Health Center, Madison, WI 53711, USA
    Viruses 5:654-62. 2013
    ..These data provide evidence for prion plaques altering local transition metal distribution in the TSE-infected central nervous system...
  20. ncbi request reprint NMR investigation of enzymatic coupling of sulfonamide antimicrobials with humic substances
    Heidi M Bialk
    Molecular and Environmental Toxicology Center, Department of Soil Science, A, University of Wisconsin, Madison, Wisconsin 53706, USA
    Environ Sci Technol 42:106-12. 2008
    ..Because the free anilinic nitrogen is required for the bioactivity of sulfonamide antimicrobials, nucleophilic addition occurring through this moiety could result in the biochemical inactivation of these compounds...
  21. ncbi request reprint Rapid gas chromatography-mass spectrometry screening method for human pharmaceuticals, hormones, antioxidants and plasticizers in water
    Mary A Soliman
    Department of Environmental Health Sciences, University of California Los Angeles, CHS 46 081, Charles E Young Drive South, Los Angeles, CA 90095, USA
    J Chromatogr A 1029:223-37. 2004
    ..Screening for nontarget compounds in the treated effluent samples indicated the method could be readily extended to include additional analytes...
  22. pmc Highly efficient amplification of chronic wasting disease agent by protein misfolding cyclic amplification with beads (PMCAb)
    Chad J Johnson
    Environmental Chemistry and Technology Program and Department of Soil Science, University of Wisconsin, Madison, Wisconsin, United States of America
    PLoS ONE 7:e35383. 2012
    ..Additionally, we are able to amplify CWD agent from brain tissue and lymph nodes of CWD-positive white-tailed deer having Prnp alleles associated with reduced disease susceptibility...
  23. pmc Prions adhere to soil minerals and remain infectious
    Christopher J Johnson
    Program in Cellular and Molecular Biology, University of Wisconsin Madison, Madison, Wisconsin, United States of America
    PLoS Pathog 2:e32. 2006
    ..Results from our study suggest that PrP(Sc) released into soil environments may be preserved in a bioavailable form, perpetuating prion disease epizootics and exposing other species to the infectious agent...
  24. pmc Elongation kinetics of polyglutamine peptide fibrils: a quartz crystal microbalance with dissipation study
    Robert H Walters
    Department of Chemical and Biological Engineering, University of Wisconsin Madison, 1415 Engineering Drive, Madison, WI 53706, USA
    J Mol Biol 421:329-47. 2012
    ..Together, the data indicate that elongation of polyQ fibrils can occur without full consolidation to the fibril structure, resulting in variations to the aggregate structure during elongation...
  25. pmc Fate of prions in soil: a review
    Christen B Smith
    Environmental Chemistry and Technology Program, Univ of Wisconsin, 1525 Observatory Dr, Madison, WI 53706, USA
    J Environ Qual 40:449-61. 2011
    ..An improved understanding of the processes affecting the mobility, persistence, and bioaviailability of prions in soil is needed for the management of TSE-contaminated environments...
  26. ncbi request reprint Complexation of the antibiotic tetracycline with humic acid
    Cheng Gu
    Environmental Chemistry and Technology Program, University of Wisconsin Madison, Madison, WI 53706, United States
    Chemosphere 66:1494-501. 2007
    ..Sorption-desorption hysteresis was observed; both sorption and desorption isotherms were well described by the Freundlich equation...
  27. ncbi request reprint Adsorption of pathogenic prion protein to quartz sand
    Xin Ma
    Department of Soil Science, University of Wisconsin, Madison, Wisconsin 53706, USA
    Environ Sci Technol 41:2324-30. 2007
    ..g., burial in lime or fly ash), may increase PrPsc mobility. Similarly, PrPsc mobility may increase as a landfill ages, due to increases in pH and decreases in l of the leachate...
  28. ncbi request reprint A citric acid-derived ligand for modular functionalization of metal oxide surfaces via "click" chemistry
    Lee M Bishop
    Department of Chemistry, University of Wisconsin Madison, 1101 University Avenue, Madison, Wisconsin 53706, USA
    Langmuir 28:1322-9. 2012
    ..The broad utility of this strategy for the modular functionalization of metal oxide surfaces was demonstrated by its application in the CuAAC modification of ZnO, Fe(2)O(3), TiO(2), and WO(3) nanoparticles...
  29. pmc Ultraviolet-ozone treatment reduces levels of disease-associated prion protein and prion infectivity
    Christopher J Johnson
    Department of Comparative Biosciences, University of Wisconsin Madison, 1656 Linden Dr, Madison, WI 53706, USA
    BMC Res Notes 2:121. 2009
    ..Using larger UV-ozone doses or combining UV-ozone treatment with other decontaminant methods may allow the sterilization of TSE-contaminated materials...
  30. pmc Absolute quantification of prion protein (90-231) using stable isotope-labeled chymotryptic peptide standards in a LC-MRM AQUA workflow
    Robert Sturm
    Department of Chemistry, University of Wisconsin, Madison, WI 53705, USA
    J Am Soc Mass Spectrom 23:1522-33. 2012
    ..To the authors' knowledge, this is the first report on the use of a non-tryptic peptide in a LC-MRM AQUA workflow...
  31. ncbi request reprint Kinetics of oxytetracycline reaction with a hydrous manganese oxide
    Kennedy F Rubert
    Molecular and Environmental Toxicology Center, University of Wisconsin, Madison, Wisconsin 53706, USA
    Environ Sci Technol 40:7216-21. 2006
    ....
  32. pmc Engineered nanomaterial transformation under oxidative environmental conditions: development of an in vitro biomimetic assay
    Kevin M Metz
    Environmental Chemistry and Technology Program, Department of Chemistry, University of Wisconsin, Madison, Wisconsin 53706, USA
    Environ Sci Technol 43:1598-604. 2009
    ..This assay provides a new method to characterize transformations of nanoscale materials expected to occur under oxidative environmental conditions...
  33. ncbi request reprint Adsorption of sulfonamide antimicrobial agents to clay minerals
    Juan Gao
    Department of Soil Science, and Environmental Chemistry and Technology Program, University of Wisconsin, Madison, Wisconsin 53706, USA
    Environ Sci Technol 39:9509-16. 2005
    ..Our results highlight the importance of considering sulfonamide speciation and clay surface charge density in predicting the transport of these antimicrobials...
  34. ncbi request reprint Integrated hamiltonian sampling: a simple and versatile method for free energy simulations and conformational sampling
    Toshifumi Mori
    Department of Chemistry and Theoretical Chemistry Institute, University of Wisconsin Madison, 1101 University Avenue, Madison, Wisconsin 53706, United States
    J Phys Chem B 118:8210-20. 2014
    ..The relation of IHS to several related sampling methods such as Hamiltonian replica exchange molecular dynamics and λ-dynamics is also briefly discussed. ..
  35. doi request reprint Titanium dioxide nanoparticles produce phototoxicity in the developing zebrafish
    Ofek Bar-Ilan
    Pharmaceutical Sciences Division, School of Pharmacy, University of Wisconsin Madison, Madison, WI 53705 2222, USA
    Nanotoxicology 6:670-9. 2012
    ..This concept should serve as a guide for future nanotoxicological studies aiming to identify potential hazardous effects on organisms...
  36. ncbi request reprint Laccase-mediated michael addition of 15N-sulfapyridine to a model humic constituent
    Heidi M Bialk
    Molecular and Environmental Toxicology Center, Department of Biochemistry, University of Wisconsin, Madison, Wisconsin 53706, USA
    Environ Sci Technol 41:3593-600. 2007
    ..Michael addition to quinone-like structures in soil organic matter is expected to diminish the mobility and biological activity of sulfonamide antimicrobials...
  37. doi request reprint Aminoglycoside antibiotics may interfere with microbial amino sugar analysis
    Chao Liang
    Department of Soil Science, University of Wisconsin, Madison, WI 53706, USA
    J Chromatogr A 1216:5296-301. 2009
    ..Application of the aldononitrile acetate derivatization method to samples (especially in selective microbial cultures using aminoglycosides as inhibitors) requires that potential interference be evaluated...
  38. ncbi request reprint Fate of oxytetracycline in streams receiving aquaculture discharges: model simulations
    Peter E Rose
    River Studies Center, University of Wisconsin, La Crosse, Wisconsin 54601, USA
    Environ Toxicol Chem 24:40-50. 2005
    ....
  39. doi request reprint Electrostatic effects on deposition of multiple phospholipid bilayers at oxide surfaces
    Timothy A Oleson
    Department of Geoscience, 1215 West Dayton Street, University of Wisconsin, Madison, WI 53706, USA
    J Colloid Interface Sci 352:327-36. 2010
    ..Results have potential implications for biomedical, industrial, and environmental remediation applications involving SPBs and for proto-cell stability in origin-of-life hypotheses...
  40. ncbi request reprint Cross-coupling of sulfonamide antimicrobial agents with model humic constituents
    Heidi M Bialk
    Molecular and Environmental Toxicology Center, University of Wisconsin, Madison, Wisconsin 53706, USA
    Environ Sci Technol 39:4463-73. 2005
    ..Our results indicate that sulfonamide antimicrobials may be chemically incorporated into humic substances. This may result in their diminished mobility, bioavailability, and biological activity...
  41. ncbi request reprint Influence of aeration on hydrophobic organic contaminant distribution and diffusive flux in estuarine sediments
    Chen Hung Michael Lin
    Department of Environmental Health Sciences, University of California, Los Angeles, California 90095, USA
    Environ Sci Technol 37:3547-54. 2003
    ..10). This latter result represented approximately a doubling in diffusive flux. In the systems studied, facilitation of TeCB transport across the sediment-water interface by organic colloids did not appear important...

Research Grants1

  1. Impact of Microparticles on Oral TSE Infections
    Joel A Pedersen; Fiscal Year: 2010
    ..Our studies support the hypothesis that soil and soil microparticles bind to prion protein (PrPSc) enhancing disease transmission for scrapie and CWD. ..