Research Topics
| Joel A PedersenSummaryAffiliation: University of Wisconsin Country: USA Publications
Research Grants
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Detail Information
Publications
Xenobiotic organic compounds in runoff from fields irrigated with treated wastewaterJoel A Pedersen
Environmental Science and Engineering Program, University of California Los Angeles, Charles E Young Drive South, CHS 46 081, 90095 1772, USA
J Agric Food Chem 51:1360-72. 2003..Agricultural runoff also represented a source of allochthonous natural organic matter to the stream system...- Organophosphorus insecticides in agricultural and residential runoff: field observations and implications for total maximum daily load developmentJoel A Pedersen
Environmental Science and Engineering Program, University of California, Los Angeles, California 90095, USA
Environ Sci Technol 40:2120-7. 2006..A relative potency factor approach is introduced to permit evaluation of organophosphorus insecticides on a common toxicological basis and allow development of TMDLs and pollutant control strategies for these compounds as a class... - Human pharmaceuticals, hormones, and personal care product ingredients in runoff from agricultural fields irrigated with treated wastewaterJoel A Pedersen
Molecular and Environmental Toxicology Center and Department of Soil Science, University of Wisconsin, Madison, Wisconsin 53706, USA
J Agric Food Chem 53:1625-32. 2005..None of these compounds were detected by broad-spectrum analysis in samples from the same fields during runoff-producing rain events... 
Pathogenic prion protein is degraded by a manganese oxide mineral found in soilsFabio Russo
Department of Soil Science and Molecular and Environmental Toxicology Center, University of Wisconsin, Madison, WI, USA
J Gen Virol 90:275-80. 2009..Exposure to 5.6 mg MnO(2) ml(-1) (PrP(TSE) : MnO(2)=1 : 110) decreased PrP(TSE) levels by > or = 4 orders of magnitude. Manganese oxides may contribute to prion degradation in soil environments rich in these minerals...
Meat and bone meal and mineral feed additives may increase the risk of oral prion disease transmissionChristopher J Johnson
Prion Research Laboratory, USGS National Wildlife Health Center, Madison, Wisconsin, USA
J Toxicol Environ Health A 74:161-6. 2011..Our data suggest that in feed or other prion-contaminated substances consumed by animals or, potentially, humans, the addition of MBM or the presence of microparticles could heighten risks of prion disease acquisition...- Transport of the pathogenic prion protein through soilsKurt H Jacobson
Civil and Environmental Engineering, Univ of Wisconsin, Madison, WI 53706, USA
J Environ Qual 39:1145-52. 2010..In the case of infected carcasses deposited on the land surface, this may result in local sources of infectivity to other animals... - Persistence of pathogenic prion protein during simulated wastewater treatment processesGlen T Hinckley
Department of Civil and Environmental Engineering, University of Wisconsin, Madison, Wisconsin 53706, USA
Environ Sci Technol 42:5254-9. 2008..Our results suggest that if prions were to enter municipal wastewater treatment systems, most would partition to activated sludge solids, survive mesophilic anaerobic digestion, and be present in treated biosolids... - Human pharmaceuticals, antioxidants, and plasticizers in wastewater treatment plant and water reclamation plant effluentsMary A Soliman
Department of Environmental Health Sciences, University of California, Los Angeles, USA
Water Environ Res 79:156-67. 2007..Nontarget compounds in recharged groundwater appeared to be attenuated with increased residence time in the aquifer... - Transport of the pathogenic prion protein through landfill materialsKurt H Jacobson
Department of Civil and Environmental Engineering, University of Wisconsin, Madison, Wisconsin 53706, USA
Environ Sci Technol 43:2022-8. 2009..g., encasement in fine-grained soil) are used... - Occurrence of tetracycline resistance genes in aquaculture facilities with varying use of oxytetracyclineErin E Seyfried
Department of Civil and Environmental Engineering, University of Wisconsin at Madison, 3204 Engineering Hall, 1415 Engineering Drive, Madison, WI 53706, USA
Microb Ecol 59:799-807. 2010..To our knowledge, this is the first study to use genotypic and cultivation-independent methods to examine tet(R) gene occurrence associated with OTC use in aquaculture... - Interaction of the macrolide antimicrobial clarithromycin with dissolved humic acidSamuel D Sibley
Environmental Chemistry and Technology Program, and Department of Soil Science, University of Wisconsin, Madison, Wisconsin 53706, USA
Environ Sci Technol 42:422-8. 2008..CLA-ESHA association constants were similar in magnitude (10(3.9)-10(4.6) to those of many nonpolar organic contaminants, and macroscopic binding data were consistent with cation exchange dominating CLA+ -ESHA association... - Detection of known and novel adenoviruses in cattle wastes via broad-spectrum primersSamuel D Sibley
Environmental Chemistry and Technology Program, University of Wisconsin, Madison, WI 53706 1299, USA
Appl Environ Microbiol 77:5001-8. 2011..To our knowledge, this is the first study to report natural BAdV excretion in urine, BAdV detection in groundwater, and recombination in AdV of livestock origin... - NMR investigation of enzymatic coupling of sulfonamide antimicrobials with humic substancesHeidi M Bialk
Molecular and Environmental Toxicology Center, Department of Soil Science, A, University of Wisconsin, Madison, Wisconsin 53706, USA
Environ Sci Technol 42:106-12. 2008..Because the free anilinic nitrogen is required for the bioactivity of sulfonamide antimicrobials, nucleophilic addition occurring through this moiety could result in the biochemical inactivation of these compounds... - Sorption of sulfonamide antimicrobial agents to humic acid-clay complexesJuan Gao
Dep of Soil Science, Univ of Wisconsin, Madison, WI 53706, USA
J Environ Qual 39:228-35. 2010.... - Rapid gas chromatography-mass spectrometry screening method for human pharmaceuticals, hormones, antioxidants and plasticizers in waterMary A Soliman
Department of Environmental Health Sciences, University of California Los Angeles, CHS 46-081, Charles E. Young Drive South, Los Angeles, CA 90095, USA
J Chromatogr A 1029:223-37. 2004..Screening for nontarget compounds in the treated effluent samples indicated the method could be readily extended to include additional analytes... - Elongation kinetics of polyglutamine peptide fibrils: a quartz crystal microbalance with dissipation studyRobert H Walters
Department of Chemical and Biological Engineering, University of Wisconsin Madison, 1415 Engineering Drive, Madison, WI 53706, USA
J Mol Biol 421:329-47. 2012..Together, the data indicate that elongation of polyQ fibrils can occur without full consolidation to the fibril structure, resulting in variations to the aggregate structure during elongation... - Highly efficient amplification of chronic wasting disease agent by protein misfolding cyclic amplification with beads (PMCAb)Chad J Johnson
Environmental Chemistry and Technology Program and Department of Soil Science, University of Wisconsin, Madison, Wisconsin, United States of America
PLoS ONE 7:e35383. 2012..Additionally, we are able to amplify CWD agent from brain tissue and lymph nodes of CWD-positive white-tailed deer having Prnp alleles associated with reduced disease susceptibility... - Fate of prions in soil: a reviewChristen B Smith
Environmental Chemistry and Technology Program, Univ of Wisconsin, 1525 Observatory Dr, Madison, WI 53706, USA
J Environ Qual 40:449-61. 2011..An improved understanding of the processes affecting the mobility, persistence, and bioaviailability of prions in soil is needed for the management of TSE-contaminated environments... - Complexation of the antibiotic tetracycline with humic acidCheng Gu
Environmental Chemistry and Technology Program, University of Wisconsin Madison, Madison, WI 53706, United States
Chemosphere 66:1494-501. 2007..Sorption-desorption hysteresis was observed; both sorption and desorption isotherms were well described by the Freundlich equation... - A citric acid-derived ligand for modular functionalization of metal oxide surfaces via "click" chemistryLee M Bishop
Department of Chemistry, University of Wisconsin Madison, 1101 University Avenue, Madison, Wisconsin 53706, USA
Langmuir 28:1322-9. 2012..The broad utility of this strategy for the modular functionalization of metal oxide surfaces was demonstrated by its application in the CuAAC modification of ZnO, Fe(2)O(3), TiO(2), and WO(3) nanoparticles... - Adsorption of pathogenic prion protein to quartz sandXin Ma
Department of Soil Science, University of Wisconsin, Madison, Wisconsin 53706, USA
Environ Sci Technol 41:2324-30. 2007..g., burial in lime or fly ash), may increase PrPsc mobility. Similarly, PrPsc mobility may increase as a landfill ages, due to increases in pH and decreases in l of the leachate... - Absolute quantification of prion protein (90-231) using stable isotope-labeled chymotryptic peptide standards in a LC-MRM AQUA workflowRobert Sturm
Department of Chemistry, University of Wisconsin, Madison, WI 53705, USA
J Am Soc Mass Spectrom 23:1522-33. 2012..To the authors' knowledge, this is the first report on the use of a non-tryptic peptide in a LC-MRM AQUA workflow... - Ultraviolet-ozone treatment reduces levels of disease-associated prion protein and prion infectivityChristopher J Johnson
Department of Comparative Biosciences, University of Wisconsin Madison, 1656 Linden Dr, Madison, WI 53706, USA
BMC Res Notes 2:121. 2009..Using larger UV-ozone doses or combining UV-ozone treatment with other decontaminant methods may allow the sterilization of TSE-contaminated materials... - Engineered nanomaterial transformation under oxidative environmental conditions: development of an in vitro biomimetic assayKevin M Metz
Environmental Chemistry and Technology Program, Department of Chemistry, University of Wisconsin, Madison, Wisconsin 53706, USA
Environ Sci Technol 43:1598-604. 2009..This assay provides a new method to characterize transformations of nanoscale materials expected to occur under oxidative environmental conditions... - Kinetics of oxytetracycline reaction with a hydrous manganese oxideKennedy F Rubert
Molecular and Environmental Toxicology Center, University of Wisconsin, Madison, Wisconsin 53706, USA
Environ Sci Technol 40:7216-21. 2006.... - Adsorption of sulfonamide antimicrobial agents to clay mineralsJuan Gao
Department of Soil Science, and Environmental Chemistry and Technology Program, University of Wisconsin, Madison, Wisconsin 53706, USA
Environ Sci Technol 39:9509-16. 2005..Our results highlight the importance of considering sulfonamide speciation and clay surface charge density in predicting the transport of these antimicrobials... - Titanium dioxide nanoparticles produce phototoxicity in the developing zebrafishOfek Bar-Ilan
Pharmaceutical Sciences Division, School of Pharmacy, University of Wisconsin Madison, Madison, WI 53705 2222, USA
Nanotoxicology 6:670-9. 2012..This concept should serve as a guide for future nanotoxicological studies aiming to identify potential hazardous effects on organisms... - Laccase-mediated michael addition of 15N-sulfapyridine to a model humic constituentHeidi M Bialk
Molecular and Environmental Toxicology Center, Department of Biochemistry, University of Wisconsin, Madison, Wisconsin 53706, USA
Environ Sci Technol 41:3593-600. 2007..Michael addition to quinone-like structures in soil organic matter is expected to diminish the mobility and biological activity of sulfonamide antimicrobials... - Electrostatic effects on deposition of multiple phospholipid bilayers at oxide surfacesTimothy A Oleson
Department of Geoscience, 1215 West Dayton Street, University of Wisconsin, Madison, WI 53706, USA
J Colloid Interface Sci 352:327-36. 2010..Results have potential implications for biomedical, industrial, and environmental remediation applications involving SPBs and for proto-cell stability in origin-of-life hypotheses... - Aminoglycoside antibiotics may interfere with microbial amino sugar analysisChao Liang
Department of Soil Science, University of Wisconsin, Madison, WI 53706, USA
J Chromatogr A 1216:5296-301. 2009..Application of the aldononitrile acetate derivatization method to samples (especially in selective microbial cultures using aminoglycosides as inhibitors) requires that potential interference be evaluated... - Fate of oxytetracycline in streams receiving aquaculture discharges: model simulationsPeter E Rose
River Studies Center, University of Wisconsin, La Crosse, Wisconsin 54601, USA
Environ Toxicol Chem 24:40-50. 2005.... - Influence of aeration on hydrophobic organic contaminant distribution and diffusive flux in estuarine sedimentsChen-Hung Michael Lin
Department of Environmental Health Sciences, University of California, Los Angeles, California 90095, USA
Environ Sci Technol 37:3547-54. 2003..10). This latter result represented approximately a doubling in diffusive flux. In the systems studied, facilitation of TeCB transport across the sediment-water interface by organic colloids did not appear important... - Cross-coupling of sulfonamide antimicrobial agents with model humic constituentsHeidi M Bialk
Molecular and Environmental Toxicology Center, University of Wisconsin, Madison, Wisconsin 53706, USA
Environ Sci Technol 39:4463-73. 2005..Our results indicate that sulfonamide antimicrobials may be chemically incorporated into humic substances. This may result in their diminished mobility, bioavailability, and biological activity... 
Prions adhere to soil minerals and remain infectiousChristopher J Johnson
Program in Cellular and Molecular Biology, University of Wisconsin Madison, Madison, Wisconsin, United States of America
PLoS Pathog 2:e32. 2006..Results from our study suggest that PrP(Sc) released into soil environments may be preserved in a bioavailable form, perpetuating prion disease epizootics and exposing other species to the infectious agent...
Research Grants
- Impact of Microparticles on Oral TSE InfectionsJoel A Pedersen; Fiscal Year: 2010..Our studies support the hypothesis that soil and soil microparticles bind to prion protein (PrPSc) enhancing disease transmission for scrapie and CWD. ..