Research Topics
Species | Gray W PearsonSummaryAffiliation: University of Texas Southwestern Medical Center Country: USA Publications
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Detail Information
Publications
PI-3 kinase activity is necessary for ERK1/2-induced disruption of mammary epithelial architectureGray W Pearson
Molecular and Cell Biology Laboratory, Salk Institute, La Jolla, CA 92037, USA
Breast Cancer Res 11:R29. 2009..However, our limited understanding of the underlying molecular mechanisms of early-stage epithelial tumor growth has hampered the development of new forms treatment and preventative therapy...
Real-time imaging reveals that noninvasive mammary epithelial acini can contain motile cellsGray W Pearson
Molecular and Cell Biology Laboratory, Salk Institute, La Jolla, CA 92037, USA
J Cell Biol 179:1555-67. 2007..Our results identify a new mechanism for the disruption of architecture in epithelial acini and suggest that ERK1/2 can promote noninvasive motility in preinvasive mammary tumors...
