SHELLEY PAYNE

Summary

Affiliation: University of Texas
Country: USA

Publications

  1. pmc Surviving bacterial sibling rivalry: inducible and reversible phenotypic switching in Paenibacillus dendritiformis
    Avraham Be'er
    Center for Nonlinear Dynamics and Department of Physics, University of Texas at Austin, Austin, Texas, USA
    MBio 2:e00069-11. 2011
  2. pmc Anaerobic regulation of Shigella flexneri virulence: ArcA regulates Fur and iron acquisition genes
    Megan L Boulette
    The University of Texas at Austin, Section
    J Bacteriol 189:6957-67. 2007
  3. ncbi request reprint Iron and pathogenesis of Shigella: iron acquisition in the intracellular environment
    Shelley M Payne
    Section of Molecular Genetics and Microbiology, The University of Texas at Austin, Austin, TX, 78712, USA
    Biometals 19:173-80. 2006
  4. pmc Analysis of residues determining specificity of Vibrio cholerae TonB1 for its receptors
    Alexandra R Mey
    Institute for Cellular and Molecular Biology Section of Molecular Genetics and Microbiology, The University of Texas at Austin, Austin, Texas 78712 1095, USA
    J Bacteriol 185:1195-207. 2003
  5. pmc Genetics and environmental regulation of Shigella iron transport systems
    Elizabeth E Wyckoff
    Section of Molecular Genetics and Microbiology, Institute for Cellular and Molecular Biology, University of Texas, Austin, TX 78712, USA
    Biometals 22:43-51. 2009
  6. pmc Iron and fur regulation in Vibrio cholerae and the role of fur in virulence
    Alexandra R Mey
    The University of Texas, Section of Molecular Genetics and Microbiology, Austin, TX 78712 1095, USA
    Infect Immun 73:8167-78. 2005
  7. pmc RyhB, an iron-responsive small RNA molecule, regulates Shigella dysenteriae virulence
    Erin R Murphy
    University of Texas at Austin, Section of Molecular Genetics and Microbiology, 1 University Station A5000, Austin, TX 78712, USA
    Infect Immun 75:3470-7. 2007
  8. pmc Genetics and virulence association of the Shigella flexneri sit iron transport system
    Carolyn R Fisher
    The University of Texas at Austin, Molecular Genetics and Microbiology, 1 University Station A5000, Austin, TX 78712 0162, USA
    Infect Immun 77:1992-9. 2009
  9. ncbi request reprint Fur regulates acid resistance in Shigella flexneri via RyhB and ydeP
    Amanda G Oglesby
    Section of Molecular Genetics and Microbiology, The University of Texas at Austin, Austin, TX 78712, USA
    Mol Microbiol 58:1354-67. 2005
  10. pmc Identification of the Vibrio cholerae enterobactin receptors VctA and IrgA: IrgA is not required for virulence
    Alexandra R Mey
    Institute for Cellular and Molecular Biology, The University of Texas, Austin, Texas 78712 1095, USA
    Infect Immun 70:3419-26. 2002

Collaborators

  • E E Wyckoff
  • Alexandra R Mey
  • Amanda G Oglesby
  • Vishwanath Iyer
  • Angela Wilks
  • M Hong
  • Edwin V Oaks
  • Avraham Be'er
  • Carolyn R Fisher
  • Georgiana E Purdy
  • E L Florin
  • Harry L Swinney
  • Aja L Gore
  • Andreas U Kresse
  • Megan L Boulette
  • Erin R Murphy
  • Sanchita Bhadra
  • Ashima K Sharma
  • Niranjan Bose
  • Oren Kalisman
  • Gil Ariel
  • Yael Helman
  • Alexandra Sirota-Madi
  • H P Zhang
  • Eshel Ben-Jacob
  • Zhengyu Feng
  • Nicola M L L Davies
  • Helmut Tschäpe
  • Ana Maria Valle
  • Ilse Rienäcker
  • Hermann Claus
  • Hartmut Steinrück
  • Rolf Reissbrodt
  • Peter H Williams
  • Jaquelin P Dudley
  • Mary M Lozano
  • Ronald K Taylor

Detail Information

Publications24

  1. pmc Surviving bacterial sibling rivalry: inducible and reversible phenotypic switching in Paenibacillus dendritiformis
    Avraham Be'er
    Center for Nonlinear Dynamics and Department of Physics, University of Texas at Austin, Austin, Texas, USA
    MBio 2:e00069-11. 2011
    ..Thus, in contrast to persister cells, P. dendritiformis bacteria adapt to changing environmental conditions by inducible and reversible phenotypic switching...
  2. pmc Anaerobic regulation of Shigella flexneri virulence: ArcA regulates Fur and iron acquisition genes
    Megan L Boulette
    The University of Texas at Austin, Section
    J Bacteriol 189:6957-67. 2007
    ..Transcription of fur, encoding the iron-responsive transcriptional repressor of bacterial iron acquisition, was also repressed anaerobically in an ArcA-dependent manner...
  3. ncbi request reprint Iron and pathogenesis of Shigella: iron acquisition in the intracellular environment
    Shelley M Payne
    Section of Molecular Genetics and Microbiology, The University of Texas at Austin, Austin, TX, 78712, USA
    Biometals 19:173-80. 2006
    ..This regulation is mediated by the repressor protein Fur and the small RNA RyhB...
  4. pmc Analysis of residues determining specificity of Vibrio cholerae TonB1 for its receptors
    Alexandra R Mey
    Institute for Cellular and Molecular Biology Section of Molecular Genetics and Microbiology, The University of Texas at Austin, Austin, Texas 78712 1095, USA
    J Bacteriol 185:1195-207. 2003
    ..cholerae TonB1. These data suggest that the TonB box -1 position controls productive interactions with V. cholerae TonB1...
  5. pmc Genetics and environmental regulation of Shigella iron transport systems
    Elizabeth E Wyckoff
    Section of Molecular Genetics and Microbiology, Institute for Cellular and Molecular Biology, University of Texas, Austin, TX 78712, USA
    Biometals 22:43-51. 2009
    ..The effects of oxygen are also seen in infection of cultured cells by Shigella flexneri; the Sit and Iuc systems support plaque formation under aerobic conditions, whereas Feo allows plaque formation anaerobically...
  6. pmc Iron and fur regulation in Vibrio cholerae and the role of fur in virulence
    Alexandra R Mey
    The University of Texas, Section of Molecular Genetics and Microbiology, Austin, TX 78712 1095, USA
    Infect Immun 73:8167-78. 2005
    ..cholerae. Consistent with this observation, the fur mutant competed poorly with its wild-type parental strain for colonization of the infant mouse gut...
  7. pmc RyhB, an iron-responsive small RNA molecule, regulates Shigella dysenteriae virulence
    Erin R Murphy
    University of Texas at Austin, Section of Molecular Genetics and Microbiology, 1 University Station A5000, Austin, TX 78712, USA
    Infect Immun 75:3470-7. 2007
    ..Regulation of virB by RyhB implicates iron as an environmental factor contributing to the complex regulation of Shigella virulence determinants...
  8. pmc Genetics and virulence association of the Shigella flexneri sit iron transport system
    Carolyn R Fisher
    The University of Texas at Austin, Molecular Genetics and Microbiology, 1 University Station A5000, Austin, TX 78712 0162, USA
    Infect Immun 77:1992-9. 2009
    ..The Sit system is also required for virulence in a mouse lung model. The sitA mutant was able to infect the mice and induce a protective immune response but was avirulent compared to its wild-type parent strain...
  9. ncbi request reprint Fur regulates acid resistance in Shigella flexneri via RyhB and ydeP
    Amanda G Oglesby
    Section of Molecular Genetics and Microbiology, The University of Texas at Austin, Austin, TX 78712, USA
    Mol Microbiol 58:1354-67. 2005
    ..These results demonstrate that the acid sensitivity defect of the S. flexneri fur mutant is due to repression of ydeP by RyhB, most likely via repression of evgA...
  10. pmc Identification of the Vibrio cholerae enterobactin receptors VctA and IrgA: IrgA is not required for virulence
    Alexandra R Mey
    Institute for Cellular and Molecular Biology, The University of Texas, Austin, Texas 78712 1095, USA
    Infect Immun 70:3419-26. 2002
    ..These data indicate that the virulence defect in MBG40 is not due to the loss of irgA function and that irgA is unlikely to be an important virulence factor...
  11. pmc Characterization of Vibrio cholerae RyhB: the RyhB regulon and role of ryhB in biofilm formation
    Alexandra R Mey
    Institute for Cellular and Molecular Biology, The University of Texas, Austin, TX 78712 1095, USA
    Infect Immun 73:5706-19. 2005
    ..These data indicate that V. cholerae RyhB has diverse functions, ranging from iron homeostasis to the regulation of biofilm formation...
  12. pmc Vibrio cholerae VciB promotes iron uptake via ferrous iron transporters
    Alexandra R Mey
    The University of Texas at Austin, Section of Molecular Genetics and Microbiology, Austin, TX 78712 1095, USA
    J Bacteriol 190:5953-62. 2008
    ..A V. cholerae vciB mutant did not exhibit any growth defects in either in vitro or in vivo assays, possibly due to the presence of other systems with overlapping functions in this pathogen...
  13. pmc HutZ is required for efficient heme utilization in Vibrio cholerae
    Elizabeth E Wyckoff
    Section of Molecular Genetics and Microbiology, The University of Texas at Austin, Austin, Texas 78712 0162, USA
    J Bacteriol 186:4142-51. 2004
    ..HutZ may act as a heme storage protein, and it may also function as a shuttle protein that increases the efficiency of heme trafficking from the membrane to heme-containing proteins...
  14. ncbi request reprint Iron acquisition in Vibrio cholerae
    Elizabeth E Wyckoff
    Section of Molecular Genetics and Microbiology, University of Texas at Austin, 1 University Station A5000, Austin, TX 78712, USA
    Biometals 20:405-16. 2007
    ..The redundancy in iron transport systems has made it more difficult to determine the role of individual systems in vivo and in vitro, but it may reflect the overall importance of iron in the growth and survival of V. cholerae...
  15. pmc CsrA and Cra influence Shigella flexneri pathogenesis
    Aja L Gore
    Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, TX 78712, USA
    Infect Immun 78:4674-82. 2010
    ..flexneri invasion and plaque formation...
  16. ncbi request reprint Induction of expression of hfq by DksA is essential for Shigella flexneri virulence
    Ashima K Sharma
    Section of Molecular Genetics and Microbiology, The University of Texas at Austin, Austin, TX 78712, USA
    Mol Microbiol 62:469-79. 2006
    ....
  17. pmc Shigella dysenteriae ShuS promotes utilization of heme as an iron source and protects against heme toxicity
    Elizabeth E Wyckoff
    The University of Texas, Section of Molecular Genetics and Microbiology, 1 University Station A5000, Austin, TX 78712 0162, USA
    J Bacteriol 187:5658-64. 2005
    ..ShuS did not appear to store heme for future use...
  18. pmc Characterization of ferric and ferrous iron transport systems in Vibrio cholerae
    Elizabeth E Wyckoff
    University of Texas, Section of Molecular Genetics and Microbiology, 1 University Station A5000, Austin, TX 78712 0162, USA
    J Bacteriol 188:6515-23. 2006
    ..However, a mutant defective in the vibriobactin, Fbp, and Feo systems was not attenuated in a suckling mouse model, suggesting that at least one other iron transport system can be used in vivo...
  19. pmc Shigella flexneri DegP facilitates IcsA surface expression and is required for efficient intercellular spread
    Georgiana E Purdy
    Institute for Cellular and Molecular Biology and Section of Molecular Genetics and Microbiology, The University of Texas at Austin, Austin, Texas 78712, USA
    Infect Immun 70:6355-64. 2002
    ..DegP was also required for efficient polar IcsA localization in E. coli expressing icsA. In addition, the growth or survival of SM1100 was compromised compared to that of the wild type at elevated temperatures and in acidic conditions...
  20. pmc IcsA surface presentation in Shigella flexneri requires the periplasmic chaperones DegP, Skp, and SurA
    Georgiana E Purdy
    Institute for Cellular and Molecular Biology and Section of Molecular Genetics and Microbiology, The University of Texas at Austin, Austin, Texas 78712, USA
    J Bacteriol 189:5566-73. 2007
    ..Therefore, the three periplasmic folding factors DegP, Skp, and SurA were all required for IcsA localization and plaque formation by S. flexneri...
  21. pmc Lethal protein produced in response to competition between sibling bacterial colonies
    Avraham Be'er
    Department of Physics, Center for Nonlinear Dynamics, University of Texas, Austin, TX 78712, USA
    Proc Natl Acad Sci U S A 107:6258-63. 2010
    ..The presence of genes encoding homologs of dendritiformis sibling bacteriocin in other bacterial species suggests that this mechanism for self-regulation of colony growth might not be limited to P. dendritiformis...
  22. ncbi request reprint Enterohaemorrhagic Escherichia coli O157 and non-O157 serovars differ in their mechanisms for iron supply
    Andreas U Kresse
    Robert Koch Institute, Wernigerode Branch, Burgstrasse 37, D 38855 Wernigerode, Germany
    Int J Med Microbiol 297:9-15. 2007
    ..Overall our data demonstrate that O157:H7 and non-O157 serovars, in particular O26:H(-)/H11 and O103:H2, use distinctly different strategies for obtaining iron, and suggest two evolutionary distinct lines of enterhaemorrhagic E. coli...
  23. pmc Type 4 pilus biogenesis and type II-mediated protein secretion by Vibrio cholerae occur independently of the TonB-facilitated proton motive force
    Niranjan Bose
    Department of Microbiology and Immunology, Dartmouth Medical School, Hanover, New Hampshire 03755, USA
    J Bacteriol 184:2305-9. 2002
    ..In contrast, the cognate putative ATPases were required for each process and could not substitute for each other...
  24. pmc Endogenous MMTV proviruses induce susceptibility to both viral and bacterial pathogens
    Sanchita Bhadra
    Section of Molecular Genetics and Microbiology and Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, Texas, United States of America
    PLoS Pathog 2:e128. 2006
    ..Since human endogenous retroviruses also encode Sags, these studies have broad implications for pathogen-induced responses in mice and humans...

Research Grants31

  1. Characterization of the ferrous iron transporter Feo in Vibrio cholerae
    Shelley M Payne; Fiscal Year: 2011
    ..Because no system comparable to Feo is found in the human, this iron transport system may represent a new class of targets for antimicrobial therapy. ..
  2. IRON TRANSPORT AND VIRULENCE IN SHIGELLA AND E COLI
    SHELLEY PAYNE; Fiscal Year: 2000
    ..Results obtained from this study will provide basic information on genetics and regulation of potential virulence factors in an important group of pathogens and will provide data useful in design of potential vaccine strains. ..
  3. IRON TRANSPORT AND VIRULENCE IN SHIGELLA AND E COLI
    SHELLEY PAYNE; Fiscal Year: 2001
    ..Results obtained from this study will provide basic information on genetics and regulation of potential virulence factors in an important group of pathogens and will provide data useful in design of potential vaccine strains. ..
  4. V. cholerae iron transport mechanisms and pathogenesis
    SHELLEY PAYNE; Fiscal Year: 2002
    ..The third Specific Aim is to use our mutant collection, together with other reagents, to determine which transport systems are used during specific environmental conditions, and during growth in the vertebrate host. ..
  5. IRON TRANSPORT AND VIRULENCE IN SHIGELLA AND E COLI
    SHELLEY PAYNE; Fiscal Year: 2002
    ..Results obtained from this study will provide basic information on genetics and regulation of potential virulence factors in an important group of pathogens and will provide data useful in design of potential vaccine strains. ..
  6. V. cholerae iron transport mechanisms and pathogenesis
    SHELLEY PAYNE; Fiscal Year: 2003
    ..The third Specific Aim is to use our mutant collection, together with other reagents, to determine which transport systems are used during specific environmental conditions, and during growth in the vertebrate host. ..
  7. V. cholerae iron transport mechanisms and pathogenesis
    SHELLEY PAYNE; Fiscal Year: 2004
    ..The third Specific Aim is to use our mutant collection, together with other reagents, to determine which transport systems are used during specific environmental conditions, and during growth in the vertebrate host. ..
  8. V. cholerae iron transport mechanisms and pathogenesis
    SHELLEY PAYNE; Fiscal Year: 2005
    ..The third Specific Aim is to use our mutant collection, together with other reagents, to determine which transport systems are used during specific environmental conditions, and during growth in the vertebrate host. ..
  9. V. cholerae iron transport mechanisms and pathogenesis
    SHELLEY PAYNE; Fiscal Year: 2006
    ..The third Specific Aim is to use our mutant collection, together with other reagents, to determine which transport systems are used during specific environmental conditions, and during growth in the vertebrate host. ..
  10. Iron transport in Shigella and pathogenic E.coli
    SHELLEY PAYNE; Fiscal Year: 2007
    ..Our fourth specific aim is to assess expression of iron transport and other genes during intracellular growth and during infection by using microarray technology. ..
  11. ASM Summer Institute in Preparation of Careers in Microbiology - Cycle 3
    SHELLEY PAYNE; Fiscal Year: 2007
    ..abstract_text> ..
  12. IRON TRANSPORT AND VIRULENCE IN SHIGELLA AND E COLI
    SHELLEY PAYNE; Fiscal Year: 1999
    ..Results obtained from this study will provide basic information on genetics and regulation of potential virulence factors in an important group of pathogens and will provide data useful in design of potential vaccine strains. ..
  13. IRON TRANSPORT AND VIRULENCE IN SHIGELLA
    SHELLEY PAYNE; Fiscal Year: 1993
    ..flexneri invading or multiplying within host cells. This provides a tool for determining expression of virulence factors in vivo and, in the long term, will be a useful technique in design and analysis of potential vaccine strains...
  14. IRON TRANSPORT AND VIRULENCE IN SHIGELLA
    SHELLEY PAYNE; Fiscal Year: 1980
    ..Genetic studies will primarily be concerned with the involvement of phage or plasmids in virulence of Shigella...