Research Topics
Genomes and GenesSpecies | Mani N PavuluriSummaryAffiliation: University of Illinois at Chicago Country: USA Publications
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Publications
Child- and family-focused cognitive-behavioral therapy for pediatric bipolar disorder: development and preliminary resultsMani N Pavuluri
University of Illinois at Chicago, USA
J Am Acad Child Adolesc Psychiatry 43:528-37. 2004..a biological theory of excessive reactivity, and (3). the role of environmental stressors in outcome. CFF-CBT actively engages parents and children over 12 hour-long sessions...
Risperidone and divalproex differentially engage the fronto-striato-temporal circuitry in pediatric mania: a pharmacological functional magnetic resonance imaging studyMani N Pavuluri
Pediatric Brain Research and Intervention Center, Institute for Juvenile Research, Colbeth Clinic, University of Illinois at Chicago, IL 60608, USA
J Am Acad Child Adolesc Psychiatry 51:157-170.e5. 2012..The current study examined the impact of risperidone and divalproex on affective and working memory circuitry in patients with pediatric bipolar disorder (PBD)...
Double-blind randomized trial of risperidone versus divalproex in pediatric bipolar disorder: fMRI outcomesMani N Pavuluri
Institute for Juvenile Research, Center for Cognitive Medicine, Department of Psychiatry, University of Illinois at Chicago, Chicago, IL 60608, USA
Psychiatry Res 193:28-37. 2011..Increased amygdala activity at baseline is a potential biomarker predicting poor treatment response to both the risperidone and divalproex...
A pharmacological functional magnetic resonance imaging study probing the interface of cognitive and emotional brain systems in pediatric bipolar disorderMani N Pavuluri
Institute for Juvenile Research, Department of Psychiatry, University of Illinois at Chicago, Chicago, Illinois 60608, USA
J Child Adolesc Psychopharmacol 20:395-406. 2010..This functional magnetic resonance imaging (fMRI) study investigated the effects of pharmacotherapy on brain function underlying affect dysregulation and cognitive function in pediatric bipolar disorder (PBD)...
Emotion processing influences working memory circuits in pediatric bipolar disorder and attention-deficit/hyperactivity disorderAlessandra M Passarotti
Institute for Juvenile Research and Center for Cognitive Medicine, University of Illinois at Chicago, Chicago, IL 60608, USA
J Am Acad Child Adolesc Psychiatry 49:1064-80. 2010..This functional magnetic resonance imaging (fMRI) study examined how working memory circuits are affected by face emotion processing in pediatric bipolar disorder (PBD) and attention-deficit/hyperactivity disorder (ADHD)...
Neural correlates of incidental and directed facial emotion processing in adolescents and adultsAlessandra M Passarotti
Institute for Juvenile Research, Department of Psychiatry, University of Illinois at Chicago, 912 South Wood Street M C 913, Chicago, IL 60612, USA
Soc Cogn Affect Neurosci 4:387-98. 2009..These results indicate that the neural circuitries for affect regulation are still developing in adolescence and have not yet reached the adult level...
Facial emotion processing in acutely ill and euthymic patients with pediatric bipolar disorderLindsay S Schenkel
Department of Psychiatry, University of Illinois at Chicago, USA
J Am Acad Child Adolesc Psychiatry 46:1070-9. 2007..However, the extent to which these deficits represent state- and trait-related factors is unclear. We investigated facial affect processing in acutely ill and clinically stabilized children with PBD and matched healthy subjects...
Neurocognitive function in pediatric bipolar disorder: 3-year follow-up shows cognitive development lagging behind healthy youthsMani N Pavuluri
Department of Psychiatry, University of Illinois at Chicago, Institute for Juvenile Research and Center for Cognitive Medicine, 912 South Wood Street M C 913, Chicago, IL 60612, USA
J Am Acad Child Adolesc Psychiatry 48:299-307. 2009..Longitudinal follow-up of neurocognitive functioning in people with pediatric bipolar disorder (PBD) was conducted to characterize the developmental trajectory of cognitive disabilities in this disorder...
Enhanced prefrontal function with pharmacotherapy on a response inhibition task in adolescent bipolar disorderMani N Pavuluri
Institute for Juvenile Research and Center for Cognitive Medicine, University of Illinois at Chicago, 912 South Wood St M C 913, Chicago, IL 60612, USA
J Clin Psychiatry 71:1526-34. 2010..The aim of the current study is to determine whether pharmacotherapy normalizes cognitive circuitry function supporting voluntary behavioral inhibition in adolescent bipolar disorder...
Child mania rating scale: development, reliability, and validityMani N Pavuluri
Department of Psychiatry, University of Illinois at Chicago, 60612, USA
J Am Acad Child Adolesc Psychiatry 45:550-60. 2006..To develop a reliable and valid parent-report screening instrument for mania, based on DSM-IVsymptoms...
Double-blind randomized trial of risperidone versus divalproex in pediatric bipolar disorderMani N Pavuluri
Department of Psychiatry, Institute for Juvenile Research, University of Illinois at Chicago, USA
Bipolar Disord 12:593-605. 2010..To determine the relative effects of risperidone and divalproex in pediatric mania...
Pharmacotherapy impacts functional connectivity among affective circuits during response inhibition in pediatric maniaMani N Pavuluri
Pediatric Brain Research and Intervention Center, Institute for Juvenile Research, Berger Colbeth Clinic, University of Illinois at Chicago, IL 60608, USA
Behav Brain Res 226:493-503. 2012..The differential influence of an antipsychotic and an anti-epileptic medication on the functional connectivity across affective and cognitive neural operations in PBD was examined...
Parent-child interactions in pediatric bipolar disorderLindsay S Schenkel
Pediatric Mood Disorders Program, Institute for Juvenile Research, University of Illinois at Chicago, IL, USA
J Clin Psychol 64:422-37. 2008..These findings have implications for the development of interventions that focus on the quality of parent-child relationships, in addition to symptom management, in the treatment of PBD...
Early childhood temperament in pediatric bipolar disorder and attention deficit hyperactivity disorderAmy E West
Pediatric Mood Disorders Program, Department of Psychiatry, University of Illinois at Chicago, Chicago, IL 60608, USA
J Clin Psychol 64:402-21. 2008..Difficult premorbid temperament characteristics may be a specific indicator of a bipolar diathesis, or might signal underlying dysfunction in affective processes that significantly increase risk for a mood disorder...
Accuracy of brief and full forms of the Child Mania Rating ScaleDavid B Henry
Institute for Juvenile Research, Department of Psychiatry, University of Illinois at Chicago, Chicago, IL 60608, USA
J Clin Psychol 64:368-81. 2008..93 with 11 items from the full CMRS-P that were not used in constructing the brief version, and showed accuracy comparable to the full scale in differentiating BD from ADHD, and in discriminating among bipolar subtypes...
Biological risk factors in pediatric bipolar disorderMani N Pavuluri
Department of Psychiatry, University of Illinois at Chicago, Chicago, Illinois, USA
Biol Psychiatry 60:936-41. 2006..The current study attempted to determine whether neurodevelopmental and acquired brain abnormalities are more common in pediatric bipolar disorder (PBD)...
Maintenance model of integrated psychosocial treatment in pediatric bipolar disorder: A pilot feasibility studyAmy E West
Department of Psychiatry, University of Illinois at Chicago, Chicago, IL, USA
J Am Acad Child Adolesc Psychiatry 46:205-12. 2007....
Brain-derived neurotrophic factor gene expression in pediatric bipolar disorder: effects of treatment and clinical responseGhanshyam N Pandey
Department of Psychiatry, University of Illinois at Chicago, Chicago, IL 60612, USA
J Am Acad Child Adolesc Psychiatry 47:1077-85. 2008..The observed structural abnormality in the brains of patients with mood disorders has been related to abnormal brain-derived neurotrophic factor (BDNF) function, suggesting an important role for BDNF in these disorders...
Effectiveness of lamotrigine in maintaining symptom control in pediatric bipolar disorderMani N Pavuluri
University of Illinois at Chicago, Chicago, Illinois, USA
J Child Adolesc Psychopharmacol 19:75-82. 2009..The aim of this study was to test the effectiveness and safety of lamotrigine in maintenance of manic and depressive symptom control in pediatric bipolar disorder (PBD)...
Neurocognitive function in unmedicated manic and medicated euthymic pediatric bipolar patientsMani N Pavuluri
Center for Cognitive Medicine, Department of Psychiatry, University of Illinois at Chicago, 912 South Wood St M C 913, Chicago, IL 60612, USA
Am J Psychiatry 163:286-93. 2006....
Decreased protein kinase C (PKC) in platelets of pediatric bipolar patients: effect of treatment with mood stabilizing drugsGhanshyam N Pandey
University of Illinois at Chicago, Department of Psychiatry, 1601 West Taylor Street, Chicago, IL 60612, USA
J Psychiatr Res 42:106-16. 2008....
Affective neural circuitry during facial emotion processing in pediatric bipolar disorderMani N Pavuluri
Center for Cognitive Medicine, Department of Psychiatry, University of Illinois at Chicago, Chicago, Illinois 60612, USA
Biol Psychiatry 62:158-67. 2007..Identifying pathophysiology in affect processing circuitry that supports the ability to assess facial emotions might facilitate understanding of affect regulation in pediatric bipolar disorder...
Divalproex sodium for pediatric mixed mania: a 6-month prospective trialMani N Pavuluri
Pediatric Mood Disorders Research Program, Department of Psychiatry, University of Illinois at Chicago, Chicago, IL 60612, USA
Bipolar Disord 7:266-73. 2005..This prospective 6-month open trial examined the effectiveness and safety of divalproex sodium (DVPX) in pediatric mixed mania...
An fMRI study of the neural correlates of incidental versus directed emotion processing in pediatric bipolar disorderMani N Pavuluri
Department of Psychiatry, University of Illinois at Chicago, Institute for Juvenile Research and Center for Cognitive Medicine, 912 South Wood Street M C 913, Chicago, IL 60612, USA
J Am Acad Child Adolesc Psychiatry 48:308-19. 2009..To use functional neuroimaging to probe the affective circuitry dysfunctions underlying disturbances in emotion processing and emotional reactivity in pediatric bipolar disorder (PBD)...
Amygdala functional connectivity predicts pharmacotherapy outcome in pediatric bipolar disorderEzra Wegbreit
Pediatric Brain Research and Intervention Center, Department of Psychiatry, Colbeth Clinic, University of Illinois at Chicago, Chicago, Illinois 60608, USA
Brain Connect 1:411-22. 2011..These findings suggest that increased functional integration of the amygdala within the frontolimbic network might be a biomarker of general mood stabilizer medication responsivity in bipolar disorder...
Psychosocial treatments for childhood and adolescent bipolar disorderAmy E West
University of Illinois at Chicago, 1747 West Roosevelt Road, Chicago, IL 60608, USA
Child Adolesc Psychiatr Clin N Am 18:471-82, x-xi. 2009....
Impact of neurocognitive function on academic difficulties in pediatric bipolar disorder: A clinical translationMani N Pavuluri
Department of Psychiatry, University of Illinois at Chicago, Chicago, Illinois, USA
Biol Psychiatry 60:951-6. 2006..Investigation of the degree to which neuropsychological deficits might contribute to those academic problems is needed to aid in the recognition and intervention for school achievement difficulties in PBD...
Brain functional domains inform therapeutic interventions in attention-deficit/hyperactivity disorder and pediatric bipolar disorderAlessandra M Passarotti
Pediatric BRAIN Center, Institute for Juvenile Research, University of Illinois at Chicago, 1747, West Roosevelt Road, M C 747, Chicago, IL 60612, USA
Expert Rev Neurother 11:897-914. 2011....
A pharmacotherapy algorithm for stabilization and maintenance of pediatric bipolar disorderMani N Pavuluri
Pediatric Mood Disorders Clinic, Bipolar Research Program, Department of Psychiatry, University of Illinois at Chicago, 60612 7347, USA
J Am Acad Child Adolesc Psychiatry 43:859-67. 2004..To assess the feasibility and effectiveness of an evidence-based pharmacotherapy algorithm in the treatment of pediatric bipolar disorder...
Diffusion tensor imaging study of white matter fiber tracts in pediatric bipolar disorder and attention-deficit/hyperactivity disorderMani N Pavuluri
Center for Cognitive Medicine, University of Illinois Medical Center at Chicago, 912 S Wood Street, Chicago, IL 60612 7327, USA
Biol Psychiatry 65:586-93. 2009..To investigate microstructure of white matter fiber tracts in pediatric bipolar disorder (PBD) and attention-deficit/hyperactivity disorder (ADHD)...
Open-label prospective trial of risperidone in combination with lithium or divalproex sodium in pediatric maniaMani N Pavuluri
Pediatric Bipolar Research Program, Department of Psychiatry, University of Illinois at Chicago UIC, Chicago, IL 60612, USA
J Affect Disord 82:S103-11. 2004....
Effects of early intervention on the course of bipolar disorder: theories and realitiesMani N Pavuluri
Department of Psychiatry, Institute for Juvenile Research, Chicago, IL 60612, USA
Curr Psychiatry Rep 12:490-8. 2010..The current review develops a point of view bridging scientific developments to where comprehensive, multipronged treatment strategies find their clinical application-a model that is similarly applicable in adult bipolar disorder...
Enhanced working and verbal memory after lamotrigine treatment in pediatric bipolar disorderMani N Pavuluri
Center for Cognitive Medicine, University of Illinois Medical Center at Chicago, Chicago, IL 60612, USA
Bipolar Disord 12:213-20. 2010..To examine the treatment impact of lamotrigine on the neurocognitive profile of patients with pediatric bipolar disorder (PBD)...
A one-year open-label trial of risperidone augmentation in lithium nonresponder youth with preschool-onset bipolar disorderMani N Pavuluri
Pediatric Bipolar Research Program, Department of Psychiatry, University of Illinois at Chicago UIC, 912 South Wood Street, Chicago, IL 60612, USA
J Child Adolesc Psychopharmacol 16:336-50. 2006..The aim of this study was to assess the safety and efficacy of risperidone augmentation of lithium in preschool-onset bipolar disorder (BD) among youth who insufficiently respond to lithium monotherapy...
Brain-derived neurotrophic factor gene and protein expression in pediatric and adult depressed subjectsGhanshyam N Pandey
University of Illinois at Chicago, Department of Psychiatry MC 912, 1601 West Taylor Street, Chicago, IL 60612, United States
Prog Neuropsychopharmacol Biol Psychiatry 34:645-51. 2010....
An fMRI study of the interface between affective and cognitive neural circuitry in pediatric bipolar disorderMani N Pavuluri
Center for Cognitive Medicine at the University of Illinois at Chicago UIC, Chicago, IL 60612, USA
Psychiatry Res 162:244-55. 2008..This pattern of functional alteration in affective and cognitive circuitry may contribute to the reduced capacity for affect regulation and behavioral self-control in pediatric bipolar disorder...
Neural correlates of response inhibition in pediatric bipolar disorder and attention deficit hyperactivity disorderAlessandra M Passarotti
Center for Cognitive Medicine, University of Illinois Medical Center at Chicago, Chicago, IL 60612, USA
Psychiatry Res 181:36-43. 2010..Prefrontal dysfunction was observed in both the ADHD and PBD groups relative to HC, although it was more extensive and accompanied by subcortical overactivity in ADHD...
Integrating functional brain neuroimaging and developmental cognitive neuroscience in child psychiatry researchMani N Pavuluri
Center for Cognitive Medicine at the University of Illinois at Chicago, Chicago, IL 60612, USA
J Am Acad Child Adolesc Psychiatry 47:1273-88. 2008..To provide an overview of clinical research aiming to develop a mechanistic understanding of brain dysfunction in child psychiatric disorders...
Neural bases of emotional processing in pediatric bipolar disorderMani N Pavuluri
Center for Cognitive Medicine and Institute for Juvenile Research, University of Illinois at Chicago, 912 South Wood Street M C 913, Chicago, IL 60612, USA
Expert Rev Neurother 8:1381-7. 2008..Early recognition of the external clinical features and the underlying emotional processing circuitry will help us understand the neurobiological underpinnings of this disorder and offer innovative ideas for early intervention...
Pediatric bipolar disorder: a review of the past 10 yearsMani N Pavuluri
Pediatric Mood Disorders Clinic and Bipolar Research Program, Department of Psychiatry, University of Illinois at Chicago, 60612 7327, USA
J Am Acad Child Adolesc Psychiatry 44:846-71. 2005..To review the literature of the past decade covering the epidemiology, clinical characteristics, assessment, longitudinal course, biological and psychosocial correlates, and treatment and prevention of pediatric bipolar disorder (BD)...
Psychotic symptoms in pediatric bipolar disorderMani N Pavuluri
Center for Cognitive Medicine, University of Illinois at Chicago, USA
J Affect Disord 80:19-28. 2004..There is under-recognition or misdiagnosis of pediatric bipolar disorder with psychotic features. It is of major public health importance to recognize psychosis in bipolar disorder...
Anxiety and fear. Discriminant validity in the child and adolescent practitioner's perspectiveMani N Pavuluri
Institute for Juvenile Research, University of Illinois at Chicago, Chicago 60612, USA
Eur Child Adolesc Psychiatry 11:273-80. 2002....
Topiramate plus risperidone for controlling weight gain and symptoms in preschool maniaMani N Pavuluri
J Child Adolesc Psychopharmacol 12:271-3. 2002
