Andrew T Pavia

Summary

Affiliation: University of Utah
Country: USA

Publications

  1. pmc What is the role of respiratory viruses in community-acquired pneumonia?: What is the best therapy for influenza and other viral causes of community-acquired pneumonia?
    Andrew T Pavia
    Division of Pediatric Infectious Diseases, Department of Pediatrics, University of Utah, Salt Lake City, UT 84108, USA
    Infect Dis Clin North Am 27:157-75. 2013
  2. doi request reprint Laboratory creation of a highly transmissible H5N1 influenza virus: balancing substantial risks and real benefits
    Andrew T Pavia
    University of Utah, Salt Lake City, USA
    Ann Intern Med 156:463-5. 2012
  3. pmc Viral infections of the lower respiratory tract: old viruses, new viruses, and the role of diagnosis
    Andrew T Pavia
    Department of Pediatrics, Division of Pediatric Infectious Diseases, University of Utah, Salt Lake City, UT 84108, USA
    Clin Infect Dis 52:S284-9. 2011
  4. doi request reprint The changing epidemiology of invasive pneumococcal disease at a tertiary children's hospital through the 7-valent pneumococcal conjugate vaccine era: a case for continuous surveillance
    Krow Ampofo
    Division of Pediatric Infectious Diseases, Department of Pediatrics, University of Utah Health Sciences Center, Salt Lake City, UT 84108, USA
    Pediatr Infect Dis J 31:228-34. 2012
  5. pmc Invasive pneumococcal disease in infants younger than 90 days before and after introduction of PCV7
    Liset Olarte
    Division of Pediatric Infectious Diseases, Department of Pediatrics, University of Utah Health Sciences Center, Salt Lake City, UT, USA
    Pediatrics 132:e17-24. 2013
  6. pmc Molecular epidemiology of pediatric pneumococcal empyema from 2001 to 2007 in Utah
    Carrie L Byington
    Department of Pediatrics, University of Utah, 295 Chipeta Way, Salt Lake City, UT 84108, USA
    J Clin Microbiol 48:520-5. 2010
  7. doi request reprint Epidemiology of Streptococcus pneumoniae-induced hemolytic uremic syndrome in Utah children
    Jeffrey M Bender
    Department of Pediatrics, Pediatric Infectious Diseases, University of Utah, Salt Lake City, Utah, USA
    Pediatr Infect Dis J 29:712-6. 2010
  8. pmc Seasonality of acute otitis media and the role of respiratory viral activity in children
    Chris Stockmann
    Department of Pediatrics, Division of Pediatric Infectious Diseases, University of Utah Health Sciences Center, Salt Lake City, UT, USA
    Pediatr Infect Dis J 32:314-9. 2013
  9. pmc Molecular analysis improves pathogen identification and epidemiologic study of pediatric parapneumonic empyema
    Anne J Blaschke
    Department of Pediatrics, University of Utah, Salt, Lake City, UT, USA
    Pediatr Infect Dis J 30:289-94. 2011
  10. pmc Evolving epidemiologic characteristics of invasive group a streptococcal disease in Utah, 2002-2010
    Chris Stockmann
    Division of Pediatric Infectious Diseases, Department of Pediatrics, University of Utah Health Sciences Center, Salt Lake City, 84108, USA
    Clin Infect Dis 55:479-87. 2012

Collaborators

Detail Information

Publications44

  1. pmc What is the role of respiratory viruses in community-acquired pneumonia?: What is the best therapy for influenza and other viral causes of community-acquired pneumonia?
    Andrew T Pavia
    Division of Pediatric Infectious Diseases, Department of Pediatrics, University of Utah, Salt Lake City, UT 84108, USA
    Infect Dis Clin North Am 27:157-75. 2013
    ..Better ways to diagnose viral CAP and to integrate detection into management, and better treatment options for noninfluenza respiratory viral infections are needed...
  2. doi request reprint Laboratory creation of a highly transmissible H5N1 influenza virus: balancing substantial risks and real benefits
    Andrew T Pavia
    University of Utah, Salt Lake City, USA
    Ann Intern Med 156:463-5. 2012
    ..It would be irresponsible to adopt either extreme solution: to prevent and censor the research or to allow unlimited distribution without careful review by an independent group, such as the NSABB...
  3. pmc Viral infections of the lower respiratory tract: old viruses, new viruses, and the role of diagnosis
    Andrew T Pavia
    Department of Pediatrics, Division of Pediatric Infectious Diseases, University of Utah, Salt Lake City, UT 84108, USA
    Clin Infect Dis 52:S284-9. 2011
    ..In addition, rapid identification of viral infections can help control nosocomial transmission...
  4. doi request reprint The changing epidemiology of invasive pneumococcal disease at a tertiary children's hospital through the 7-valent pneumococcal conjugate vaccine era: a case for continuous surveillance
    Krow Ampofo
    Division of Pediatric Infectious Diseases, Department of Pediatrics, University of Utah Health Sciences Center, Salt Lake City, UT 84108, USA
    Pediatr Infect Dis J 31:228-34. 2012
    ..We recognized an opportunity to describe the changes in epidemiology, clinical syndromes, and serotype distribution during a 14-year period including 4 years before vaccine introduction and spanning the entire PCV7 era...
  5. pmc Invasive pneumococcal disease in infants younger than 90 days before and after introduction of PCV7
    Liset Olarte
    Division of Pediatric Infectious Diseases, Department of Pediatrics, University of Utah Health Sciences Center, Salt Lake City, UT, USA
    Pediatrics 132:e17-24. 2013
    ..We evaluated the changes that occurred after PCV7 introduction among Utah infants aged 1 to 90 days, too young to be fully immunized...
  6. pmc Molecular epidemiology of pediatric pneumococcal empyema from 2001 to 2007 in Utah
    Carrie L Byington
    Department of Pediatrics, University of Utah, 295 Chipeta Way, Salt Lake City, UT 84108, USA
    J Clin Microbiol 48:520-5. 2010
    ..Serotype switch was not documented. Replacement disease with common ST of serotypes 1,3, 7F, and 19A rather than serotype switch was responsible for the increase in PPE in Utah children...
  7. doi request reprint Epidemiology of Streptococcus pneumoniae-induced hemolytic uremic syndrome in Utah children
    Jeffrey M Bender
    Department of Pediatrics, Pediatric Infectious Diseases, University of Utah, Salt Lake City, Utah, USA
    Pediatr Infect Dis J 29:712-6. 2010
    ..Few studies examine the Streptococcus pneumoniae serotypes associated with HUS. Our objective was to describe the epidemiology of S. pneumoniae-related HUS (SP-HUS) and the serotypes associated with HUS in Utah children...
  8. pmc Seasonality of acute otitis media and the role of respiratory viral activity in children
    Chris Stockmann
    Department of Pediatrics, Division of Pediatric Infectious Diseases, University of Utah Health Sciences Center, Salt Lake City, UT, USA
    Pediatr Infect Dis J 32:314-9. 2013
    ..AOM and respiratory viruses both display seasonal variation. Our objective was to examine the temporal association between circulating respiratory viruses and the occurrence of pediatric ambulatory care visits for AOM...
  9. pmc Molecular analysis improves pathogen identification and epidemiologic study of pediatric parapneumonic empyema
    Anne J Blaschke
    Department of Pediatrics, University of Utah, Salt, Lake City, UT, USA
    Pediatr Infect Dis J 30:289-94. 2011
    ..Epidemiologic study is complicated by the low frequency of positive cultures. We sought to describe the epidemiology of PPE in children using molecular analysis of pleural fluid...
  10. pmc Evolving epidemiologic characteristics of invasive group a streptococcal disease in Utah, 2002-2010
    Chris Stockmann
    Division of Pediatric Infectious Diseases, Department of Pediatrics, University of Utah Health Sciences Center, Salt Lake City, 84108, USA
    Clin Infect Dis 55:479-87. 2012
    ..Invasive group A Streptococcus (GAS) infections are associated with substantial morbidity and mortality. Recent national surveillance data report stable rates of invasive GAS disease, although these may not capture geographic variation...
  11. pmc Increasing incidence of invasive Haemophilus influenzae disease in adults, Utah, USA
    Matthew P Rubach
    University of Utah, Salt Lake City, Utah, USA
    Emerg Infect Dis 17:1645-50. 2011
    ..The case-fatality rate was 22%. The incidence of invasive H. influenzae in Utah adults appears to be increasing. Invasive H. influenzae infection disproportionately affected the elderly and was associated with a high mortality rate...
  12. doi request reprint Influenza virus infection in infants less than three months of age
    Jeffrey M Bender
    University of Utah School of Medicine, Department of Pediatrics, Division of Pediatric Infectious Diseases, PO Box 581289, Salt Lake City, UT, USA
    Pediatr Infect Dis J 29:6-9. 2010
    ..We evaluated the presentation, outcomes, and the risk of serious bacterial infection (SBI) in infants <3 months old with influenza virus infection...
  13. doi request reprint Streptococcus pneumoniae serotypes in Utah adults at the end of the PCV7 era
    Brian A Kendall
    Department of Medicine, University of Utah, Salt Lake City, UT, United States
    Vaccine 29:9123-6. 2011
    ..Adult and pediatric IPD serotypes are closely associated in Utah. PCV13 vaccination in Utah children is likely to significantly impact IPD in Utah adults...
  14. doi request reprint Evolution of the epidemiology of pneumococcal disease among Utah children through the vaccine era
    Krow Ampofo
    Division of Pediatric Infectious Diseases, Department of Pediatrics, University of Utah Health Sciences Center, Salt Lake City, UT 84108, USA
    Pediatr Infect Dis J 30:1100-3. 2011
    ..Despite decreases in PD among Utah children, complicated pneumonia/empyema has increased during the 7-valent pneumococcal conjugate vaccine era...
  15. pmc Association of 2009 pandemic influenza A (H1N1) infection and increased hospitalization with parapneumonic empyema in children in Utah
    Krow Ampofo
    Division of Pediatric Infectious Diseases, Department of Pediatrics, University of Utah Health Sciences Center, Salt Lake City, UT, USA
    Pediatr Infect Dis J 29:905-9. 2010
    ..We examined the relationship between circulating 2009 H1N1 and the occurrence of secondary bacterial parapneumonic empyema in children...
  16. doi request reprint Pneumococcal meningitis in children: epidemiology, serotypes, and outcomes from 1997-2010 in utah
    Chris Stockmann
    MSc, Division of Pediatric Infectious Diseases, University of Utah Health Sciences Center, 295 Chipeta Way, 2S010, Salt Lake City, UT 84108
    Pediatrics 132:421-8. 2013
    ..However, cases continue to occur. It is unknown whether meningitis due to PCV7 and non-PCV7 serotypes causes similar morbidity and mortality...
  17. pmc Rapid identification of pathogens from positive blood cultures by multiplex polymerase chain reaction using the FilmArray system
    Anne J Blaschke
    Department of Pediatrics, University of Utah, Salt Lake City, UT, USA
    Diagn Microbiol Infect Dis 74:349-55. 2012
    ..aureus and vancomycin-resistant enterococci. The FA BC panel is an accurate method for the rapid identification of pathogens and resistance genes from blood culture...
  18. doi request reprint Costs and infant outcomes after implementation of a care process model for febrile infants
    Carrie L Byington
    Department of Pediatrics, University of Utah, Salt Lake City, Utah 84108, USA
    Pediatrics 130:e16-24. 2012
    ..Well-appearing febrile infants with SBI cannot be distinguished from those without by examination alone. Variation in care resulting in both undertreatment and overtreatment is common...
  19. doi request reprint Invasive Haemophilus influenzae disease in Utah children: an 11-year population-based study in the era of conjugate vaccine
    Jeffrey M Bender
    Division of Pediatric Infectious Diseases, Department of Pediatrics, University of Utah, Salt Lake City, Utah 84158, USA
    Clin Infect Dis 50:e41-6. 2010
    ..We aimed to report the epidemiology and serotypes of invasive H. influenzae disease in children from Utah in the post-Hib vaccine era...
  20. doi request reprint Oseltamivir-resistant influenza A 2009 H1N1 virus in immunocompromised patients
    Brianne A Couturier
    ARUP Laboratories, Salt Lake City, UT, USA
    Influenza Other Respi Viruses 4:199-204. 2010
    ..First-line treatment of influenza A 2009 H1N1 relies on neuraminidase inhibitors such as oseltamivir. Resistance conferred by the H275Y neuraminidase gene mutation is concerning and likely to increase...
  21. pmc Characteristics of antimicrobial studies registered in the USA through ClinicalTrials.Gov
    Chris Stockmann
    Department of Paediatrics, University of Utah School of Medicine, Salt Lake City, UT, USA
    Int J Antimicrob Agents 42:161-6. 2013
    ..Leveraging the application of these data to guide the careful selection of antimicrobial agents will be essential to preserve their utility for years to come. ..
  22. doi request reprint Development and validation of a risk score for predicting hospitalization in children with influenza virus infection
    Jeffrey M Bender
    Department of Pediatrics, Division of Pediatric Infectious Disease, University of Utah School of Medicine, Salt Lake City, UT 84132, USA
    Pediatr Emerg Care 25:369-75. 2009
    ..Many children with influenza seek care in emergency settings during seasonal influenza epidemics. We hypothesized that certain features could predict the need for hospitalization in children with influenza...
  23. pmc Parapneumonic empyema deaths during past century, Utah
    Jeffrey M Bender
    Division of Pediatric Infectious Diseases, Department of Pediatrics, University of Utah School of Medicine, Salt Lake City, Utah 84132, USA
    Emerg Infect Dis 15:44-8. 2009
    ..Vaccine strategies and antimicrobial drug stockpiling to control empyema will be important as we prepare for the next influenza pandemic...
  24. doi request reprint Tularemia with vesicular skin lesions may be mistaken for infection with herpes viruses
    Carrie L Byington
    Department of Pediatrics, University of Utah, Salt Lake City, UT 84132, USA
    Clin Infect Dis 47:e4-6. 2008
    ..Clinicians must recognize the cutaneous manifestations of tularemia and be able to distinguish these from lesions seen with herpes viruses...
  25. ncbi request reprint Gordonia species: emerging pathogens in pediatric patients that are identified by 16S ribosomal RNA gene sequencing
    Anne J Blaschke
    Department of Pediatrics, Division of Pediatric Infectious Diseases, University of Utah, Salt Lake City, UT, USA
    Clin Infect Dis 45:483-6. 2007
    ....
  26. ncbi request reprint Epidemiology, complications, and cost of hospitalization in children with laboratory-confirmed influenza infection
    Krow Ampofo
    Division of Pediatric Infectious Disease, University of Utah Health Sciences Center, 30 North 1900 E, Room 2A100, Salt Lake City, UT 84132, USA
    Pediatrics 118:2409-17. 2006
    ..Influenza causes significant morbidity among children. Previous studies used indirect case ascertainment methods with little cost data. We sought to measure the burden of laboratory-confirmed influenza from hospitalized children...
  27. ncbi request reprint Temporal trends of invasive disease due to Streptococcus pneumoniae among children in the intermountain west: emergence of nonvaccine serogroups
    Carrie L Byington
    Department of Pediatrics, University of Utah, Salt Lake City, UT 84132, USA
    Clin Infect Dis 41:21-9. 2005
    ..Use of the heptavalent pneumococcal conjugate vaccine (PCV-7 [Prevnar]) has been associated with decreased a incidence of invasive pneumococcal disease (IPD) among children in the United States...
  28. ncbi request reprint Serious bacterial infections in febrile infants younger than 90 days of age: the importance of ampicillin-resistant pathogens
    Carrie L Byington
    Department of Pediatrics, University of Utah Division of General Pediatrics, Salt Lake City, Utah 84132, USA
    Pediatrics 111:964-8. 2003
    ..Recommendations for initial antibiotic therapy for the febrile infant 1 to 90 days old were developed when infections with GBS were common and antibiotic resistance was rare...
  29. ncbi request reprint The effect of rapid respiratory viral diagnostic testing on antibiotic use in a children's hospital
    Carrie L Byington
    Department of Pediatric Infectious Diseases, University of Utah, 50 N Medical Drive, Salt Lake City, UT 84132, USA
    Arch Pediatr Adolesc Med 156:1230-4. 2002
    ..Overprescribing of antimicrobials for viral illness is a factor contributing to increasing antimicrobial resistance among bacterial pathogens encountered in pediatrics...
  30. doi request reprint Feasibility of elementary school children's use of hand gel and facemasks during influenza season
    Mandy A Allison
    Division of General Pediatrics, University of Utah, Salt Lake City, UT 84158, USA
    Influenza Other Respi Viruses 4:223-9. 2010
    ..The feasibility of non-pharmacologic interventions to prevent influenza's spread in schools is not well known...
  31. ncbi request reprint An epidemiological investigation of a sustained high rate of pediatric parapneumonic empyema: risk factors and microbiological associations
    Carrie L Byington
    Department of Pediatrics, University of Utah, Salt Lake City, UT, 84132, USA
    Clin Infect Dis 34:434-40. 2002
    ..0001 for each factor). The increasing incidence of empyema was associated with infection due to S. pneumoniae serotype 1, outpatient treatment with certain antibiotics, ibuprofen use, and varicella...
  32. pmc Pneumococcal necrotizing pneumonia in Utah: does serotype matter?
    Jeffrey M Bender
    Department of Pediatrics, Division of Infectious Diseases, University of Utah, USA
    Clin Infect Dis 46:1346-52. 2008
    ..Our objectives were to describe temporal trends in PNP and to evaluate pneumococcal serotypes associated with PNP in Utah...
  33. pmc Therapeutic monitoring of voriconazole in children less than three years of age: a case report and summary of voriconazole concentrations for ten children
    Elizabeth H Doby
    Department of Pediatrics, University of Utah, Salt Lake City, UT, USA
    Pediatr Infect Dis J 31:632-5. 2012
    ..Trough concentrations were unpredictable based on dose, highlighting the need to follow values during therapy...
  34. doi request reprint Coccidioides immitis meningitis in a patient with hyperimmunoglobulin E syndrome due to a novel mutation in signal transducer and activator of transcription
    Annie E Powers
    Department of Pediatrics, University of Utah School of Medicine, Salt Lake City, Utah 84132, USA
    Pediatr Infect Dis J 28:664-6. 2009
    ..We report the first case of Coccidioides immitis meningitis in a patient with HIES. Coccidioides should be included in the differential diagnosis for central nervous system infections in HIES patients...
  35. doi request reprint Family clusters of variant X-linked chronic granulomatous disease
    Jeffrey M Bender
    Department of Pediatrics, University of Utah School of Medicine, Salt Lake City, Utah, USA
    Pediatr Infect Dis J 28:529-33. 2009
    ..A high index of suspicion in the setting of unusual infections such as Burkholderia cepacia pneumonia is essential to make the diagnosis. Family screening can lead to early intervention, prophylaxis, and appropriate genetic counseling...
  36. pmc Public health communication with frontline clinicians during the first wave of the 2009 influenza pandemic
    Catherine J Staes
    Department of Biomedical Informatics, University of Utah School of Medicine, Salt Lake City, UT 84112, USA
    J Public Health Manag Pract 17:36-44. 2011
    ..Communication between public health authorities and frontline clinicians is critical, yet public health agencies, medical societies, and healthcare delivery organizations have all called for improvements...
  37. pmc Extended-spectrum beta-lactamase-producing pathogens in a children's hospital: a 5-year experience
    Anne J Blaschke
    Division of Pediatric Infectious Diseases, Department of Pediatrics, University of Utah, PO Box 581289, Salt Lake City, UT 84158, USA
    Am J Infect Control 37:435-41. 2009
    ..In addition, we sought to evaluate the characteristics of children affected...
  38. doi request reprint Rapid increase in use of antiviral therapy for hospitalized children with influenza during the 2009 H1N1 epidemic
    Adam L Hersh
    Division of Pediatric Infectious Diseases, University of Utah, Salt Lake City, UT, USA
    Pediatr Infect Dis J 30:895-7. 2011
    ..This increased sharply to 84% during the 2009 H1N1 period, indicating a favorable response by physicians to clinical guidelines...
  39. doi request reprint Bartonella vinsonii endocarditis in an adolescent with congenital heart disease
    Liset Olarte
    Division of Pediatric Infectious Diseases, Department of Pediatrics, University of Utah, Salt Lake City, UT 84108, USA
    Pediatr Infect Dis J 31:531-4. 2012
    ..berkhoffii endocarditis in a 19-year-old male with congenital heart disease. Diagnosis was established by Bartonella antibodies detected by immunofluorescence, and polymerase chain reaction amplification and sequencing from blood...
  40. doi request reprint Antibiotic prescribing in ambulatory pediatrics in the United States
    Adam L Hersh
    Department of Pediatrics, University of Utah, Salt Lake City, UT 84108, USA
    Pediatrics 128:1053-61. 2011
    ..Broad-spectrum antibiotic use is increasing, which adds unnecessary cost and promotes the development of antibiotic resistance...
  41. doi request reprint Seasonal invasive pneumococcal disease in children: role of preceding respiratory viral infection
    Krow Ampofo
    Division of Pediatric Infectious Disease, Department of Pediatrics, University of Utah Health Sciences Center, Salt Lake City, Utah 84132, USA
    Pediatrics 122:229-37. 2008
    ..Our objective was to demonstrate correlations between invasive pneumococcal disease in children and circulating respiratory viruses...
  42. doi request reprint Evidence for a heritable predisposition to death due to influenza
    Frederick S Albright
    Department of Pharmacotherapy, University of Utah College of Pharmacy, Salt Lake City, USA
    J Infect Dis 197:18-24. 2008
    ..These data provide strong support for a heritable contribution to predisposition to death due to influenza...
  43. ncbi request reprint Predictors of fatality in postdiarrheal hemolytic uremic syndrome
    Robert S Oakes
    Pediatric Nephrology, University of Utah School of Medicine, Salt Lake City, Utah, USA
    Pediatrics 117:1656-62. 2006
    ..Describe the cause of deaths among patients with postdiarrheal hemolytic uremic syndrome (HUS) and identify predictors of death at the time of hospital admission...
  44. doi request reprint Possible intrafamilial transmission of Toxocara causing eosinophilic meningitis in an infant
    Merle Keller
    Department of Pediatrics, University of Utah, Salt Lake City, UT 84132, USA
    Pediatr Infect Dis J 27:849-50. 2008
    ..We report a case in an infant resulting in eosinophilic meningitis and prolonged fever. The case illustrates probable intrafamilial transmission, a mode of transmission that has not been previously documented...