Robert Paul

Summary

Affiliation: University of Missouri-St. Louis
Country: USA

Publications

  1. pmc Neuropsychological outcomes in adults commencing highly active anti-retroviral treatment in South Africa: a prospective study
    John A Joska
    Department of Psychiatry and Mental Health, University of Cape Town, Cape Town, South Africa
    BMC Infect Dis 12:39. 2012
  2. pmc Neuroimaging markers of human immunodeficiency virus infection in South Africa
    JODI M HEAPS
    Department of Psychology, University of Missouri Saint Louis, Saint Louis, MO 63121, USA
    J Neurovirol 18:151-6. 2012
  3. pmc Normative scores for a brief neuropsychological battery for the detection of HIV-associated neurocognitive disorder (HAND) among South Africans
    Dinesh Singh
    Department of Psychiatry, University of Kwa Zulu Natal, Durban, South Africa
    BMC Res Notes 3:28. 2010
  4. ncbi request reprint Neuropsychological and neuroimaging outcome of HIV-associated progressive multifocal leukoencephalopathy in the era of antiretroviral therapy
    Robert H Paul
    University of Missouri St Louis, Behavioral Neuroscience, St Louis, MO 63121, USA
    J Integr Neurosci 6:191-203. 2007
  5. pmc Chronic cigarette smoking and the microstructural integrity of white matter in healthy adults: a diffusion tensor imaging study
    Robert H Paul
    Department of Psychology, Behavioral Neuroscience, University of Missouri, St Louis, MO 63121, USA
    Nicotine Tob Res 10:137-47. 2008
  6. doi request reprint Relative sensitivity of magnetic resonance spectroscopy and quantitative magnetic resonance imaging to cognitive function among nondemented individuals infected with HIV
    Robert H Paul
    Department of Psychology, Behavioral Neuroscience, University of Missouri, St Louis, St Louis, Missouri 63121 4400, USA
    J Int Neuropsychol Soc 14:725-33. 2008
  7. pmc Neuroimaging signatures and cognitive correlates of the montreal cognitive assessment screen in a nonclinical elderly sample
    Robert Paul
    Department of Psychology, University of Missouri St Louis, Behavioral Neuroscience, St Louis, MO 63121, USA
    Arch Clin Neuropsychol 26:454-60. 2011
  8. ncbi request reprint Proton MRS and neuropsychological correlates in AIDS dementia complex: evidence of subcortical specificity
    Robert H Paul
    Department of Behavioral Neuroscience, University of Missouri, St Louis, St Louis, MO 63121, USA
    J Neuropsychiatry Clin Neurosci 19:283-92. 2007
  9. pmc Development of normative neuropsychological performance in Thailand for the assessment of HIV-associated neurocognitive disorders
    Jodi Heaps
    Department of Psychology and Behavioral Neuroscience, University of Missouri, St Louis, MO 63121, USA
    J Clin Exp Neuropsychol 35:1-8. 2013
  10. pmc Independent effects of HIV, aging, and HAART on brain volumetric measures
    Beau M Ances
    Department of Neurology, Washington University School of Medicine, St Louis, MO 63110, USA
    J Acquir Immune Defic Syndr 59:469-77. 2012

Research Grants

Detail Information

Publications66

  1. pmc Neuropsychological outcomes in adults commencing highly active anti-retroviral treatment in South Africa: a prospective study
    John A Joska
    Department of Psychiatry and Mental Health, University of Cape Town, Cape Town, South Africa
    BMC Infect Dis 12:39. 2012
    ..To date, there have been no cohort studies of the impact of highly active anti-retroviral treatment (HAART) in South Africa where clade C HIV is predominant...
  2. pmc Neuroimaging markers of human immunodeficiency virus infection in South Africa
    JODI M HEAPS
    Department of Psychology, University of Missouri Saint Louis, Saint Louis, MO 63121, USA
    J Neurovirol 18:151-6. 2012
    ....
  3. pmc Normative scores for a brief neuropsychological battery for the detection of HIV-associated neurocognitive disorder (HAND) among South Africans
    Dinesh Singh
    Department of Psychiatry, University of Kwa Zulu Natal, Durban, South Africa
    BMC Res Notes 3:28. 2010
    ..To assess memory and recall, we used the memory item of the International HIV Dementia Scale (IHDS)...
  4. ncbi request reprint Neuropsychological and neuroimaging outcome of HIV-associated progressive multifocal leukoencephalopathy in the era of antiretroviral therapy
    Robert H Paul
    University of Missouri St Louis, Behavioral Neuroscience, St Louis, MO 63121, USA
    J Integr Neurosci 6:191-203. 2007
    ....
  5. pmc Chronic cigarette smoking and the microstructural integrity of white matter in healthy adults: a diffusion tensor imaging study
    Robert H Paul
    Department of Psychology, Behavioral Neuroscience, University of Missouri, St Louis, MO 63121, USA
    Nicotine Tob Res 10:137-47. 2008
    ..Additional studies are needed to further explore differences in white matter integrity between smokers and nonsmokers...
  6. doi request reprint Relative sensitivity of magnetic resonance spectroscopy and quantitative magnetic resonance imaging to cognitive function among nondemented individuals infected with HIV
    Robert H Paul
    Department of Psychology, Behavioral Neuroscience, University of Missouri, St Louis, St Louis, Missouri 63121 4400, USA
    J Int Neuropsychol Soc 14:725-33. 2008
    ..However, basal ganglia size remains an important contributor to cognitive status in this population. Longitudinal studies are needed to determine the evolution of these imaging correlates of HIV-cognitive impairment in HIV...
  7. pmc Neuroimaging signatures and cognitive correlates of the montreal cognitive assessment screen in a nonclinical elderly sample
    Robert Paul
    Department of Psychology, University of Missouri St Louis, Behavioral Neuroscience, St Louis, MO 63121, USA
    Arch Clin Neuropsychol 26:454-60. 2011
    ..These results suggest that additional studies are needed to define the significance of MoCA scores relative to brain integrity among an older population...
  8. ncbi request reprint Proton MRS and neuropsychological correlates in AIDS dementia complex: evidence of subcortical specificity
    Robert H Paul
    Department of Behavioral Neuroscience, University of Missouri, St Louis, St Louis, MO 63121, USA
    J Neuropsychiatry Clin Neurosci 19:283-92. 2007
    ..Prospective studies are needed to elucidate the evolution of these changes in the setting of antiretroviral therapy...
  9. pmc Development of normative neuropsychological performance in Thailand for the assessment of HIV-associated neurocognitive disorders
    Jodi Heaps
    Department of Psychology and Behavioral Neuroscience, University of Missouri, St Louis, MO 63121, USA
    J Clin Exp Neuropsychol 35:1-8. 2013
    ..These results highlight the continued need for the development of normative data within local populations. The use of Western norms as a comparison group could lead to inaccurate identification of HAND in culturally distinct groups...
  10. pmc Independent effects of HIV, aging, and HAART on brain volumetric measures
    Beau M Ances
    Department of Neurology, Washington University School of Medicine, St Louis, MO 63110, USA
    J Acquir Immune Defic Syndr 59:469-77. 2012
    ..Neurocognitive impairment remains prevalent in HIV-infected (HIV+) individuals despite highly active antiretroviral therapy (HAART). We assessed the impact of HIV, HAART, and aging using structural neuroimaging...
  11. ncbi request reprint Relative contributions of the cerebellar vermis and prefrontal lobe volumes on cognitive function across the adult lifespan
    Robert Paul
    University of Missouri St Louis, Behavioral Neuroscience, Department of Psychology, St Louis, MO 63121, USA
    Neurobiol Aging 30:457-65. 2009
    ..Our results are consistent with the frontal aging hypothesis...
  12. pmc Performances on the CogState and standard neuropsychological batteries among HIV patients without dementia
    Edgar Turner Overton
    Washington University School of Medicine, St Louis, MO, USA
    AIDS Behav 15:1902-9. 2011
    ..The test battery requires additional evaluation, specifically for identifying persons with mild impairment, a state upon which interventions may be effective...
  13. pmc The relationship between early life stress and microstructural integrity of the corpus callosum in a non-clinical population
    Robert Paul
    University of Missouri St Louis, St Louis, MO, USA
    Neuropsychiatr Dis Treat 4:193-201. 2008
    ..However, studies have not examined the relationship between ELS and the microstructural integrity of the brain...
  14. doi request reprint Body mass index and neurocognitive functioning across the adult lifespan
    Kelly M Stanek
    Department of Psychology, University of Alabama, Tuscaloosa, AL 35487, USA
    Neuropsychology 27:141-51. 2013
    ..The current study was designed to clarify the cognitive profile of obesity by examining performance across multiple cognitive domains in adults with wide-ranging age and weight status...
  15. ncbi request reprint Body mass index and neuropsychological function in healthy children and adolescents
    John Gunstad
    Department of Psychology, Kent State University, Kent, OH 44242, USA
    Appetite 50:246-51. 2008
    ..Further work is needed to clarify the inconsistent findings between adults and minors...
  16. ncbi request reprint Behavioral problems as predictors of functional abilities of vascular dementia patients
    Tricia M Zawacki
    Department of Psychology, Georgia State University, Atlanta, Georgia 30303, USA
    J Neuropsychiatry Clin Neurosci 14:296-302. 2002
    ..These findings highlight the importance of apathy as an independent factor associated with functional independence beyond general cognitive abilities...
  17. ncbi request reprint Age effects in time estimation: relationship to frontal brain morphometry
    John Gunstad
    Department of Psychology, Kent Hall, Kent State University, Kent, OH 44242, USA
    J Integr Neurosci 5:75-87. 2006
    ..These results indicate that healthy aging is associated with altered time estimation and suggest that changes in frontal brain regions mediate these effects...
  18. ncbi request reprint Handedness and cognition across the healthy lifespan
    John Gunstad
    Department of Psychology, Kent State University, Kent, Ohio 44242, USA
    Int J Neurosci 117:477-85. 2007
    ..No interaction-among handedness, sex, and age were found. These findings indicate cognitive differences associated with handedness exist independent of medical and psychiatric confounds. Further work is needed to clarify these findings...
  19. ncbi request reprint Elevated body mass index is associated with executive dysfunction in otherwise healthy adults
    John Gunstad
    Department of Psychology, Kent Hall, Kent State University, Kent, OH 44242, USA
    Compr Psychiatry 48:57-61. 2007
    ..Further research is needed to identify the etiology of these deficits and whether they resolve after weight loss...
  20. doi request reprint Relationship between body mass index and brain volume in healthy adults
    John Gunstad
    Department of Psychology, Kent State University, Kent, OH 44242, USA
    Int J Neurosci 118:1582-93. 2008
    ..These findings support an independent relationship between BMI and brain structure and demonstrate that these differences are not limited to older adults...
  21. pmc Subjective cognitive complaints relate to white matter hyperintensities and future cognitive decline in patients with cardiovascular disease
    Andreana P Haley
    Department of Psychology, The University of Texas at Austin, Austin, TX, USA
    Am J Geriatr Psychiatry 17:976-85. 2009
    ..This study examined the longitudinal relationship among self-reported cognitive difficulties, depression, and performance on objective tests of global cognition in patients with CVD...
  22. ncbi request reprint Cross-cultural assessment of neuropsychological performance and electrical brain function measures: additional validation of an international brain database
    Robert H Paul
    Department of Psychology, Behavioral Neuroscience, University of Missouri, St Louis, Missouri 63121, USA
    Int J Neurosci 117:549-68. 2007
    ..These findings indicate a high degree of similarity in neurocognitive and electrophysiological function among individuals residing in developed Western cultures, consistent with a traitlike status and the high heritability of the EEG...
  23. pmc Relation of brain natriuretic peptide levels to cognitive dysfunction in adults > 55 years of age with cardiovascular disease
    John Gunstad
    Department of Psychology, Kent State University, Kent, Ohio, USA
    Am J Cardiol 98:538-40. 2006
    ..002), a measure of verbal and nonverbal abstraction abilities. In conclusion, the results of the present study provide the first evidence for an independent relation between BNP and cognitive dysfunction in older adults with CVD...
  24. ncbi request reprint Dissociation of the component processes of attention in healthy adults
    John Gunstad
    Kent State University, Department of Psychology, Kent Hall, Kent, OH 44242, USA
    Arch Clin Neuropsychol 21:645-50. 2006
    ..Future studies including both neuropsychological testing and functional neuroimaging may provide important insight into the underpinnings of attentional processes...
  25. pmc Blood pressure and cognitive function in older adults with cardiovascular disease
    John Gunstad
    Department of Psychology, Kent State University, Kent, Ohio 44242, USA
    Int J Neurosci 119:2228-42. 2009
    ..Past studies link elevated blood pressure (BP) and BP variability to adverse neurocognitive changes in community samples. However, little is known about the relationship between BP indices and cognitive function in older CVD patients...
  26. pmc P-selectin 1087G/A polymorphism is associated with neuropsychological test performance in older adults with cardiovascular disease
    John Gunstad
    Department of Psychology, Kent State University, Kent, OH 44242, USA
    Stroke 40:2969-72. 2009
    ..Thus, we expected that carriers of the 1087A allele (n=43) would exhibit better cognitive functioning than persons with 2 1087G alleles (n=77) and that C-reactive protein levels would be important for this relationship...
  27. pmc Longitudinal cognitive performance in older adults with cardiovascular disease: evidence for improvement in heart failure
    Kelly M Stanek
    Department of Psychology, Kent State University, Kent, Ohio 44242, USA
    J Cardiovasc Nurs 24:192-7. 2009
    ....
  28. ncbi request reprint Cognitive status of young and older cigarette smokers: data from the international brain database
    Robert H Paul
    Centers for Behavioral and Preventive Medicine, Department of Psychiatry, Brown Medical School, Providence, RI 02903, USA
    J Clin Neurosci 13:457-65. 2006
    ..Cigarette smoking is associated with isolated and subtle cognitive difficulties among very healthy individuals...
  29. ncbi request reprint Regional white matter and neuropsychological functioning across the adult lifespan
    Adam M Brickman
    Taub Institute for Research on Alzheimer s Disease and the Aging Brain, Columbia University Medical Center, New York, NY 10032, USA
    Biol Psychiatry 60:444-53. 2006
    ..The current study utilized magnetic resonance imaging (MRI) to more fully elucidate the relationship among age, regional white matter, and neuropsychological functioning...
  30. ncbi request reprint Computer-mediated measurement and subjective ratings of white matter hyperintensities in vascular dementia: relationships to neuropsychological performance
    Kelly Davis Garrett
    Neuropsychology Program, Drexel University, Philadelphia, PA, USA
    Clin Neuropsychol 18:50-62. 2004
    ..e., psychomotor speed, executive functioning) while the visual rating scale was not. Results suggest that this computer-mediated thresholding technique is superior to visual ratings of WMHs...
  31. ncbi request reprint Insulin resistance is associated with cognition among HIV-1-infected patients: the Hawaii Aging With HIV cohort
    Victor G Valcour
    Office of Neurology and Aging Research, University of Hawaii, Leahi Hospital, 3675 Kilauea Avenue, Honolulu, HI 96816, USA
    J Acquir Immune Defic Syndr 43:405-10. 2006
    ..To determine if insulin resistance (IR) is associated with lower cognitive performance among HIV-1-infected adults and to determine if advanced age magnifies risk...
  32. ncbi request reprint Diffusion tensor imaging of the corpus callosum: a cross-sectional study across the lifespan
    Nicole C R McLaughlin
    Brown Medical School, Department of Psychiatry and Human Behavior, Providence, RI 02912, USA
    Int J Dev Neurosci 25:215-21. 2007
    ..These results define the microstructural development of the white matter across the lifespan. Future studies are required to examine the neurobehavioral correlates of these neuroimaging indices...
  33. ncbi request reprint Early life stress and morphometry of the adult anterior cingulate cortex and caudate nuclei
    Ronald A Cohen
    Department of Psychiatry and Human Behavior, Brown University, Providence, Rhode Island, USA
    Biol Psychiatry 59:975-82. 2006
    ..We examine whether reported adverse ELS defined as stressful and/or traumatic adverse childhood events (ACEs) is associated with smaller limbic and basal ganglia volumes...
  34. doi request reprint Disease-specific measure of quality of life for myasthenia gravis
    Larry L Mullins
    University of Oklahoma Health Sciences Center, Department of Pediatrics, Oklahoma City, Oklahoma, USA
    Muscle Nerve 38:947-56. 2008
    ..Results from this study support the use of this new measure of QOL, both clinically and in treatment trials of MG...
  35. ncbi request reprint Rates of decline distinguish Alzheimer's disease and mild cognitive impairment relative to normal aging: integrating cognition and brain function
    Belinda J Liddell
    The Brain Resource International Database and the Brain Resource Company, NSW 2007, Australia
    J Integr Neurosci 6:141-74. 2007
    ..Increasing age is the strongest risk factor for Alzheimer's disease (AD). Yet, departure from normal age-related decline for established markers of AD including memory, cognitive decline and brain function deficits, has not been quantified...
  36. ncbi request reprint Neuroimaging correlates of dementia rating scale performance at baseline and 12-month follow-up among patients with vascular dementia
    Lawrence H Sweet
    Brown University Medical School, Miriam Hospital, Providence, RI 20903, USA
    J Geriatr Psychiatry Neurol 16:240-4. 2003
    ..These findings indicate that although SH volume increases with disease progression, the relative impact of SH volume on cognitive status decreases among patients with advanced VaD...
  37. ncbi request reprint Verbal working memory and atherosclerosis in patients with cardiovascular disease: an fMRI study
    Andreana P Haley
    Department of Psychiatry and Human Behavior, Brown Medical School, Providence, Rhode Island, USA
    J Neuroimaging 17:227-33. 2007
    ..The purpose of this study was to examine the relationship between IMT and brain activity during a verbal working memory (VWM) task in patients with cardiovascular disease (CVD)...
  38. doi request reprint Cardiac dysfunction and cognition in older adults with heart failure
    Karin F Hoth
    Division of Psychosocial Medicine, National Jewish Medical and Research Center, Denver, CO 80206, USA
    Cogn Behav Neurol 21:65-72. 2008
    ..To characterize cognition in patients with moderate to severe heart failure and examine the association between 2 measures of systemic perfusion (ie, ejection fraction and cardiac index) and cognition...
  39. pmc Carotid artery intima-media thickness and cognition in cardiovascular disease
    Andreana P Haley
    Department of Psychiatry and Human Behavior, Brown Medical School, Providence, RI, United States
    Int J Cardiol 121:148-54. 2007
    ....
  40. ncbi request reprint The relationship between frontal gray matter volume and cognition varies across the healthy adult lifespan
    Molly E Zimmerman
    Department of Psychiatry and Human Behavior, Brown Medical School, Providence, Rhode Island, USA
    Am J Geriatr Psychiatry 14:823-33. 2006
    ..The goal of the current study is to examine the relationship between age-related changes in regional gray matter volumes and cognitive function in a large, cross-sectional sample of healthy adults across the lifespan...
  41. pmc Cardiac rehabilitation improves cognitive performance in older adults with cardiovascular disease
    John Gunstad
    Brown Medical School, Brown University, Box G MH, Providence, RI 02912 G, USA
    J Cardiopulm Rehabil 25:173-6. 2005
  42. ncbi request reprint The relationship of neuropsychological functioning to driving competence in older persons with early cognitive decline
    William M Whelihan
    Brown University School of Medicine, RI, USA
    Arch Clin Neuropsychol 20:217-28. 2005
    ..Neuropsychological executive and visual attention measures may play a useful role in determining competence to drive in older individuals with early-stage cognitive decline...
  43. ncbi request reprint Executive impairments predict functional declines in vascular dementia
    Patricia A Boyle
    Department of Neurology, Boston University School of Medicine, Alzheimer s Disease Center, Boston, MA, USA
    Clin Neuropsychol 18:75-82. 2004
    ..These findings demonstrate that baseline executive dysfunction is a significant and powerful predictor of future functional decline in individuals with VaD...
  44. ncbi request reprint The neuropsychological profile of vascular cognitive impairment--no dementia: comparisons to patients at risk for cerebrovascular disease and vascular dementia
    Kelly Davis Garrett
    Department of Psychiatry and Human Behavior, Brown Medical School, USA
    Arch Clin Neuropsychol 19:745-57. 2004
    ..The current findings suggest that poor cognitive flexibility and verbal retrieval in the context of preserved function in other domains may characterize the prodromal stage of VaD...
  45. ncbi request reprint Clinical correlates of cognitive decline in vascular dementia
    Robert H Paul
    Brown Medical School, Providence, Rhode Island 20903, USA
    Cogn Behav Neurol 16:40-6. 2003
    ..To determine whether demographic data, dementia severity, functional status, whole brain volume (WBV), or subcortical hyperintensity volume (SH) predict subsequent cognitive decline in vascular dementia (VaD)...
  46. ncbi request reprint Long-term citicoline (cytidine diphosphate choline) use in patients with vascular dementia: neuroimaging and neuropsychological outcomes
    Ronald A Cohen
    Department of Psychiatry and Human Behavior, Brown Medical School, Providence, R I, USA
    Cerebrovasc Dis 16:199-204. 2003
    ..This randomized, double-blind clinical trial was conducted to determine whether daily citicoline treatment improves neurocognitive and neuroimaging outcome over 12 months among patients diagnosed with vascular dementia (VaD)...
  47. ncbi request reprint The impact of apathy and depression on quality of life in patients infected with HIV
    David Tate
    Brown Medical School, Department of Psychiatry and Human Behavior, Brown Medical School, Department of Infectious Disease, Providence, Rhode Island, USA
    AIDS Patient Care STDS 17:115-20. 2003
    ..Clinicians should continue to focus on depression as an important neuropsychiatric symptom associated with HIV...
  48. ncbi request reprint Computer-related anxiety: examining the impact of technology-specific affect on the performance of a computerized neuropsychological assessment measure
    Jeffrey N Browndyke
    Department of Psychiatry Human Behavior, Miriam Hospital, Brown Medical School, Providence, Rhode Island 02903, USA
    Appl Neuropsychol 9:210-8. 2002
    ..Key words: computers, anxiety, computer-based task performance, clinical neuropsychology, Category Test..
  49. ncbi request reprint Sensitivity of the dementia rating scale in vascular dementia: comparison between two sets of criteria to define cognitive impairment
    Robert H Paul
    Brown Medical School, Providence, RI 20903, USA
    Cerebrovasc Dis 15:116-20. 2003
    ..The Dementia Rating Scale (DRS) is a common measure of cognitive function, but its sensitivity to identify deficits across cognitive domains in vascular dementia (VaD) remains unclear...
  50. ncbi request reprint The relationship of subcortical MRI hyperintensities and brain volume to cognitive function in vascular dementia
    Ronald A Cohen
    Department of Psychiatry, Brown Medical School, Providence, Rhode Island, USA
    J Int Neuropsychol Soc 8:743-52. 2002
    ..That WBV emerged as a stronger correlate of dementia raises further questions regarding the cerebral mechanisms that contribute to the development of VaD...
  51. ncbi request reprint Ratings of subjective mental fatigue relate to cognitive performance in patients with myasthenia gravis
    Robert H Paul
    Department of Psychiatry and Human Behavior, Brown Medical School, Miriam Hospital, Providence, RI, 02906, USA
    J Clin Neurosci 9:243-6. 2002
    ..The results indicate that cognitive impairments may be associated with perceived fatigue in MG...
  52. pmc Apathy is associated with volume of the nucleus accumbens in patients infected with HIV
    Robert H Paul
    Brown Medical School Department of Psychiatry and Human Behavior, Providence, RI 02903, USA
    J Neuropsychiatry Clin Neurosci 17:167-71. 2005
    ..By contrast, ratings of depression were unrelated to either apathy or nucleus accumbens volume. These findings provide preliminary evidence that apathy reflects direct involvement of the central nervous system in patients with HIV...
  53. pmc Subcortical hyperintensities impact cognitive function among a select subset of healthy elderly
    Robert H Paul
    Brown Medical School, Centers for Behavioral and Preventive Medicine, Department of Psychiatry and Human Behavior, 1 Hoppin Street, Providence, RI 02903, USA
    Arch Clin Neuropsychol 20:697-704. 2005
    ..Further, the findings suggest that cognitive aging is largely determined by factors other than SH for most older adults...
  54. pmc Neuroimaging and cardiac correlates of cognitive function among patients with cardiac disease
    Robert H Paul
    Center for Behavioral Medicine, Department of Psychiatry and Human Behavior, Brown Medical School, Providence, R I 02903, USA
    Cerebrovasc Dis 20:129-33. 2005
    ....
  55. ncbi request reprint Early life stress and adult emotional experience: an international perspective
    Ronald A Cohen
    Brown University, USA
    Int J Psychiatry Med 36:35-52. 2006
    ..Associations between ELS and current emotional distress suggest that these events have functional relevance and deserve further investigation...
  56. pmc Cognitive predictors of functional decline in vascular dementia
    Angela L Jefferson
    Alzheimer s Disease Center, Department of Neurology, Boston University Medical Center, Boston, MA 02118, USA
    Int J Geriatr Psychiatry 21:752-4. 2006
    ..This study examined changes in cognitive-functional relationships in vascular dementia (VaD) over the course of one year...
  57. ncbi request reprint Standardized assessment of cognitive functioning during development and aging using an automated touchscreen battery
    C Richard Clark
    School of Psychology, Flinders University, P O Box 2100, Adelaide, SA 5001, Australia
    Arch Clin Neuropsychol 21:449-67. 2006
    ..Overall, the test battery provided sensitive indicators on a range of cognitive functions suitable for the assessment of abnormal cognition, the evaluation of treatment effects and for longitudinal case management...
  58. pmc Object perception impairments predict instrumental activities of daily living dependence in Alzheimer's disease
    Angela L Jefferson
    Department of Neurology, University of Pennsylvania Medical Center, Philadellphia, PA, USA
    J Clin Exp Neuropsychol 28:884-97. 2006
    ..When considering multiple cognitive components simultaneously, object perception and the integrity of the inferotemporal cortex is important in the completion of functional abilities in general and IADLs in particular among AD patients...
  59. pmc Evaluating elements of executive functioning as predictors of instrumental activities of daily living (IADLs)
    Angela L Jefferson
    Department of Psychiatry and Human Behavior, Brown Medical School, Providence, RI, USA
    Arch Clin Neuropsychol 21:311-20. 2006
    ..e., working memory, generation, inhibition, planning, and sequencing) to IADLs among an older adult cohort at risk for future cognitive and functional decline...
  60. pmc C-reactive protein, but not homocysteine, is related to cognitive dysfunction in older adults with cardiovascular disease
    John Gunstad
    Brown Medical School, Providence, Rhode Island, USA
    J Clin Neurosci 13:540-6. 2006
    ..Further study is needed to identify mechanisms by which inflammatory processes impact on cognitive function and to determine whether reducing circulating levels of inflammatory markers results in improved cognition...
  61. ncbi request reprint Patterns of cognitive performance in middle-aged and older adults: A cluster analytic examination
    John Gunstad
    Department of Psychiatry, Brown Medical School, Centers for Behavioral and Preventive Medicine, Providence, RI 02903, USA
    J Geriatr Psychiatry Neurol 19:59-64. 2006
    ..Findings generally support the frontal aging hypothesis and may provide important information about healthy cognitive aging...
  62. ncbi request reprint EEG markers for cognitive decline in elderly subjects with subjective memory complaints
    David M Alexander
    The Brain Resource Company and the Brain Resource International Database, Ultimo, NSW 2007, Australia
    J Integr Neurosci 5:49-74. 2006
    ....
  63. pmc Systemic hypoperfusion is associated with executive dysfunction in geriatric cardiac patients
    Angela L Jefferson
    Department of Neurology, Alzheimer s Disease Center, Boston University School of Medicine, Robinson Complex, Suite 7800, 715 Albany Street, Boston, MA 02118 2526, USA
    Neurobiol Aging 28:477-83. 2007
    ..The executive dysfunction profile may be secondary to reduced blood flow to vulnerable subcortical structures implicated in frontal-subcortical circuitry...
  64. ncbi request reprint Preliminary validity of "integneuro": a new computerized battery of neurocognitive tests
    Robert H Paul
    Department of Psychiatry, Centers for Behavioral and Preventive Medicine, Brown Medical School, Providence, Rhode Island 02903, USA
    Int J Neurosci 115:1549-67. 2005
    ..These results support the use of IntegNeuro as a computerized cognitive system. Additional studies are needed to examine the clinical utility of the battery...
  65. ncbi request reprint Age-dependent change in executive function and gamma 40 Hz phase synchrony
    Robert H Paul
    Centers for Behavioral and Preventive Medicine, Department of Psychiatry and Human Behavior, Brown Medical School, Providence, RI 02903, USA
    J Integr Neurosci 4:63-76. 2005
    ....
  66. ncbi request reprint The serial position effect in mild and moderately severe vascular dementia
    Robert H Paul
    Department of Psychiatry and Human Behavior, Brown Medical School, Providence, Rhode Island 20906, USA
    J Int Neuropsychol Soc 8:584-7. 2002
    ....

Research Grants8

  1. Improving adherence to HAART in HIV
    Robert Paul; Fiscal Year: 2005
    This application is a request for a Mentored Patient-Oriented Research Career Award (K23) to provide Dr. Robert Paul the requisite training and expertise to investigate treatment outcome in patients infected with human immunodeficiency ..
  2. Functional Neuroimaging of Cognitive Dysfunction in HIV-HCV Co-Infection
    Robert Paul; Fiscal Year: 2006
    ..This cross-sectional association study will be the first transdiciplinary approach to HIV-HCV co-infection, and will provide important insight into the putative mechanisms underlying increased cognitive impairment in this population. ..
  3. Neuromarkers of age-related cognitive decline
    Robert Paul; Fiscal Year: 2007
    ..The present study will be the first to integrate these approaches to examine a model of age-related cognitive decline implicating the subcortical white matter. The results will significantly inform our understanding of cognitive aging. ..
  4. Neuromarkers of age-related cognitive decline
    Robert H Paul; Fiscal Year: 2010
    ..The results will significantly inform our understanding of cognitive aging. ..
  5. Neuropathogenesis of clade C HIV in South Africa
    Robert H Paul; Fiscal Year: 2010
    ..We also aim to demonstrate that these impairments correlate with proviral DNA levels and markers of novel neuroimaging signatures. ..