Research Topics
Genomes and Genes | Nipam H PatelSummaryAffiliation: University of Chicago Country: USA Publications
| Collaborators
|
Detail Information
Publications
Developmental biologists cast a net over sequenced genomesMatthias Gerberding
Howard Hughes Medical Institute, University of Chicago, 5841 S, Maryland Ave, MC1028, Chicago, IL 60637, USA
Genome Biol 3:REPORTS4032. 2002..A report on the annual meeting of the Society of Developmental Biology, Madison, Wisconsin, USA, 21-24 July 2002...
Grasshopper hunchback expression reveals conserved and novel aspects of axis formation and segmentationN H Patel
Department of Organismal Biology and Anatomy and Howard Hughes Medical Institute, University of Chicago, 5841 S Maryland Ave, MC1028, Chicago, IL 60637, USA
Development 128:3459-72. 2001....- Beyond the Hox complexN H Patel
Department of Organismal Biology and Anatomy, University of Chicago, Chicago, IL 60637, USA and Howard Hughes Medical Institute
Genome Biol 1:REVIEWS1027. 2000..Recent findings suggest the Hox complex may be just part of a larger chromosomal assemblage of homeobox-containing genes that existed in the ancestor to all vertebrates... - It's a bug's lifeN H Patel
Howard Hughes Medical Institute, University of Chicago, 5841 South Maryland Avenue MC1028, Chicago, IL 60637, USA
Proc Natl Acad Sci U S A 97:4442-4. 2000.... - Pax group III genes and the evolution of insect pair-rule patterningG K Davis
Committee on Developmental Biology, University of Chicago, Chicago, IL 60637, USA
Development 128:3445-58. 2001..This early expression of pairberry1 is reminiscent of Drosophila paired and represents the first evidence for pair-rule patterning in short germ grasshoppers or any hemimetabolous insect... - Pax3/7 genes reveal conservation and divergence in the arthropod segmentation hierarchyGregory K Davis
Committee on Developmental Biology, University of Chicago, Chicago, IL 60637, USA
Dev Biol 285:169-84. 2005.... - giant is a bona fide gap gene in the intermediate germband insect, Oncopeltus fasciatusPaul Z Liu
Howard Hughes Medical Institute, Department of Molecular and Cell Biology, and Department of Integrative Biology, University of California, Berkeley, CA 94702, USA
Development 137:835-44. 2010..This highlights the conservation of anterior patterning and evolutionary plasticity of the genetic regulation controlling posterior segmentation, even in short and intermediate germ insects... - Analysis of the expression pattern of Mysidium columbiae wingless provides evidence for conserved mesodermal and retinal patterning processes among insects and crustaceansMolly Duman-Scheel
Deparment of Molecular Genetics and Cell Biology, University of Chicago, 920 E. 58th Street, Chicago, IL 60637, USA
Dev Genes Evol 212:114-23. 2002..Analysis of mcowgexpression provides molecular evidence suggesting that the processes of heart, muscle, and eye patterning are likely to be conserved among insects and crustaceans... - Analysis of molecular marker expression reveals neuronal homology in distantly related arthropodsM Duman-Scheel
Department of Molecular Genetics and Cell Biology, University of Chicago, Chicago, IL 60637, USA
Development 126:2327-34. 1999..We conclude that despite their distant phylogenetic relationships and divergent mechanisms of neurogenesis, insects, malacostracans, branchiopods and collembolans share many common CNS components... - The ancestry of segmentationNipam H Patel
Department of Integrative Biology, Howard Hughes Medical Institute, University of California, Berkeley, Berkeley, CA 94720, USA
Dev Cell 5:2-4. 2003.... - Dynamics of Drosophila embryonic patterning network perturbed in space and time using microfluidicsElena M Lucchetta
Department of Chemistry, University of Chicago, Chicago, Illinois 60637, USA
Nature 434:1134-8. 2005..The microfluidic technology used here may prove useful to future studies, as it allows spatial and temporal regulation of embryonic development... - Nanos plays a conserved role in axial patterning outside of the DipteraSabbi Lall
HHMI/Department of Organismal Biology and Anatomy, University of Chicago, 5841 South Maryland Avenue MC1028, Chicago, IL 60637, USA
Curr Biol 13:224-9. 2003..This is consistent with the notion that an anterior gradient system is not necessary in all insects and that the posterior pole "probably conveys longitudinal polarity on the ensuing germ anlage"... - Evolution of the interaction between Hox genes and a downstream targetM F Palopoli
Howard Hughes Medical Institute, University of Chicago, Illinois 60637, USA
Curr Biol 8:587-90. 1998..We suggest that the regulatory interaction between the BX-C genes and Dll has evolved within the hexapods in a complex, segment-specific manner... - Genetic separation of the neural and cuticular patterning functions of gooseberryM Duman-Scheel
Department of Molecular Genetics and Cell Biology, University of Chicago, Illinois 60637, USA
Development 124:2855-65. 1997..In contrast to epidermal patterning, where Gsb is required to maintain wg transcription, we find that Gsb antagonizes the Wg signal that confers neuroblast (NB) 4-2 fate... - Stages of embryonic development in the amphipod crustacean, Parhyale hawaiensisWilliam E Browne
University of Chicago, Department of Molecular Genetics and Cell Biology, Committee on Developmental Biology, Chicago, IL, USA
Genesis 42:124-49. 2005..In addition, several aspects of Parhyale embryonic development make this species particularly suitable for a broad range of experimental manipulations... - Sequence and expression of grasshopper antennapedia: comparison to DrosophilaD C Hayward
Howard Hughes Medical Institute, Department of Molecular and Cell Biology, University of California, Berkeley 94720, USA
Dev Biol 172:452-65. 1995..In the CNS expression is initially limited to a few neurons, but eventually becomes widespread. Both insects show strong expression in certain homologous identified neurons and similar temporal modulation of expression... - Patterning of the branched head appendages in Schistocerca americana and Tribolium castaneumMatt W Giorgianni
Committee on Developmental Biology, University of Chicago, Chicago, IL 60637, USA
Evol Dev 6:402-10. 2004..We find that the branches of the gnathal appendages are not specified through the redeployment of the Wg-Dpp system for distal outgrowth, but our comparative studies do suggest a role for Dpp in forming furrows between tissues... - Investigating divergent mechanisms of mesoderm development in arthropods: the expression of Ph-twist and Ph-mef2 in Parhyale hawaiensisAlivia L Price
Department of Molecular Genetics and Cell Biology, Committee on Developmental Biology, University of Chicago, Chicago, Illinois 60637, USA
J Exp Zool B Mol Dev Evol 310:24-40. 2008.... - Neural cell fate in rca1 and cycA mutants: the roles of intrinsic and extrinsic factors in asymmetric division in the Drosophila central nervous systemB C Lear
Department of Molecular Genetics and Cell Biology, University of Chicago, IL 60637, USA
Mech Dev 88:207-19. 1999..While the extrinsic factors Notch and Delta are also required to attain both fates, our results indicate that Delta signal can be received from outside the sibling pair... - Cell lineage analysis of the amphipod crustacean Parhyale hawaiensis reveals an early restriction of cell fatesMatthias Gerberding
Department of Organismal Biology and Anatomy, University of Chicago, Chicago, IL 60637, USA
Development 129:5789-801. 2002..Finally, the techniques we have developed for the analysis of Parhyale development suggest that this arthropod may be particularly useful for future functional analyses of crustacean development... - Molecular genetics of crustacean feeding appendage development and diversificationW E Browne
University of Chicago, 5841 S Maryland Ave, Chicago, IL 60637, USA
Semin Cell Dev Biol 11:427-35. 2000..Here we review some of these data based on the expression patterns of the genes Ultrabithorax, abdominal - A, Sex combs reduced, and Distal-less... - The origin and evolution of segmentationG K Davis
Committee on Developmental Biology, University of Chicago, Chicago, IL 60637, USA
Trends Cell Biol 9:M68-72. 1999..This article reviews what is known about the segmentation process and considers various proposals to explain its evolution... - Neo-Darwinian developmental evolution: can we bridge the gap between pattern and process?M F Palopoli
Howard Hughes Medical Institute, MC1028, AMB N 101, 5841 South Maryland Avenue, Chicago, Illinois 60637, USA
Curr Opin Genet Dev 6:502-8. 1996..On the other hand, there is growing support for the view that adaptations often involve large-effect genes; fortunately, the candidate gene approach is well suited to this type of genetic architecture... - Evidence for stabilizing selection in a eukaryotic enhancer elementM Z Ludwig
Department of Ecology and Evolution, University of Chicago, Illinois 60637, USA
Nature 403:564-7. 2000..Sequence differences between species have functional consequences, therefore, but they are masked by other co-evolved differences. On the basis of these results, we present a model for the evolution of eukaryotic regulatory sequences... - Functional analysis of eve stripe 2 enhancer evolution in Drosophila: rules governing conservation and changeM Z Ludwig
Department of Ecology and Evolution, University of Chicago, Chicago, IL 60637, USA
Development 125:949-58. 1998..This view allows for a slow but continual turnover of functionally important changes in the stripe 2 enhancer... - Comparative methods for the analysis of gene-expression evolution: an example using yeast functional genomic dataTodd H Oakley
Ecology and Evolution, University of Chicago, USA
Mol Biol Evol 22:40-50. 2005..The comparative methods presented here are general enough to test a wide range of evolutionary hypotheses using genomic-scale data from any organism... - Conservation and divergence in molecular mechanisms of axis formationS Lall
Howard Hughes Medical Institute, University of Chicago, Chicago, Illinois 60637, USA
Annu Rev Genet 35:407-37. 2001..In this review we examine the postfertilization mechanisms underlying axis specification in Drosophila. Comparative data are then used to ask whether aspects of axis formation might be derived or ancestral... - Short, long, and beyond: molecular and embryological approaches to insect segmentationGregory K Davis
Committee on Developmental Biology, University of Chicago, Chicago Illinois 60637, USA
Annu Rev Entomol 47:669-99. 2002..These results are discussed in embryological context with an eye toward understanding the evolution of segmentation within insects... - Patterns on the insect wingRonald J Parchem
Department of Molecular and Cell Biology, University of California, Berkeley 94720 3140, USA
Curr Opin Genet Dev 17:300-8. 2007..Collectively, our understanding of formation and evolution of color pattern in insect wings is rapidly advancing because of these recent breakthroughs in several different fields... - Evolutionary biology: time, space and genomesNipam H Patel
Nature 431:28-9. 2004 - Playing by pair-rules?Gregory K Davis
Department of Ecology and Evolutionary Biology, Princeton University, USA
Bioessays 25:425-9. 2003..Recent data of Dearden et al.1 and Henry et al.,2 however, hint that a pair-rule mechanism might play a role in the segmentation process of basal arthropods and vertebrates... - The repressor activity of Even-skipped is highly conserved, and is sufficient to activate engrailed and to regulate both the spacing and stability of parasegment boundariesMiki Fujioka
Department of Microbiology and Immunology, Thomas Jefferson University, JAH490, Philadelphia, PA 19107, USA
Development 129:4411-21. 2002.... - Precision patterningNipam H Patel
Nature 415:748-9. 2002 - Gene duplication and speciation in Drosophila: evidence from the Odysseus locusChau Ti Ting
Department of Life Science, National Tsing Hua University, Hsinchu 300, Taiwan
Proc Natl Acad Sci U S A 101:12232-5. 2004.... - Genomes and evolution. From sequence to organismEvan E Eichler
Curr Opin Genet Dev 13:559-61. 2003 - Even-skipped, acting as a repressor, regulates axonal projections in DrosophilaMiki Fujioka
Department of Microbiology and Immunology, Thomas Jefferson University, 1020 Locust Street, Philadelphia, PA 19107, USA
Development 130:5385-400. 2003..Finally, homologues of Eve from diverse species were able to rescue the eve mutant phenotype, indicating conservation of both targeting and repression functions in the nervous system... - Evolutionary biology: how to build a longer beakNipam H Patel
Nature 442:515-6. 2006 - CrustaceansAnnalisa M VanHook
Department of Integrative Biology, University of California, Berkeley, CA 94530-3140, USA
Curr Biol 18:R547-50. 2008