Research Topics
| Nick C PatelSummaryAffiliation: University of Cincinnati Country: USA Publications
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Detail Information
Publications
Preliminary study of relationships among measures of depressive symptoms in adolescents with bipolar disorderNick C Patel
College of Pharmacy, Department of Psychiatry, University of Cincinnati College of Medicine, 3225 Eden Avenue, Cincinnati, OH 45267, USA
J Child Adolesc Psychopharmacol 16:327-35. 2006..We hypothesized that CDRS-R and HAM-D scores would be significantly correlated and both scales would be sensitive to change resulting from treatment...- Response and remission in adolescent mania: signal detection analyses of the young mania rating scaleNick C Patel
Division of Bipolar Disorders Research, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0004, USA
J Am Acad Child Adolesc Psychiatry 46:628-35. 2007..The purpose of this study was to determine optimal criteria for defining response and remission in adolescents with acute mania... - Phenomenology associated with age at onset in patients with bipolar disorder at their first psychiatric hospitalizationNick C Patel
College of Pharmacy, University of Cincinnati, Cincinnati, OH 45267 0004, USA
Bipolar Disord 8:91-4. 2006..To compare the clinical presentation of patients with early-onset (age <18 years) and typical-onset (age 20-30 years) bipolar disorder at the time of first hospitalization... - Ethnic differences in symptom presentation of youths with bipolar disorderNick C Patel
The College of Pharmacy, University of Cincinnati, OH 45267 0004, USA
Bipolar Disord 8:95-9. 2006..To compare symptom profiles of African-American and white adolescents with a diagnosis of bipolar disorder... - Diagnoses and antipsychotic treatment among youths in a public mental health systemNick C Patel
Department of Pharmacy Practice, College of Pharmacy, University of Cincinnati, Cincinnati, OH 45267 004, USA
Ann Pharmacother 40:205-11. 2006..The use of antipsychotics, namely newer atypical agents, has increased significantly in children and adolescents. It is important to examine diagnoses associated with antipsychotic treatment in youths... - Ethnic variation in symptoms and response to risperidone in youths with schizophrenia-spectrum disordersNick C Patel
The University of Cincinnati, 3225 Eden Avenue, PO Box 670004, Cincinnati, OH 45267 0004, USA
Soc Psychiatry Psychiatr Epidemiol 41:341-6. 2006..The purpose of this naturalistic, retrospective database study was to compare symptom presentation of children and adolescents of different ethnicities with schizophrenia-spectrum disorders, and response to risperidone... - Open-label lithium for the treatment of adolescents with bipolar depressionNick C Patel
College of Pharmacy and Department of Psychiatry, University of Cincinnati, OH 45267 0004, USA
J Am Acad Child Adolesc Psychiatry 45:289-97. 2006..We hypothesized that patients receiving open-label treatment with lithium during a 6-week period would experience a statistically and clinically significant decrease in depressive symptoms and tolerate lithium treatment fairly well... - Ziprasidone: efficacy and safety in patients with bipolar disorderNick C Patel
University of Cincinnati, College of Pharmacy and Department of Psychiatry, College of Medicine, 3225 Eden Avenue, PO Box 670004, Cincinnati, OH 45267 0004, USA
Expert Rev Neurother 6:1129-38. 2006..Ziprasidone is considered as a first-line treatment option in patients with bipolar manic or mixed episodes, with or without psychosis and displays a favorable side-effect profile... 
Lithium treatment effects on Myo-inositol in adolescents with bipolar depressionNick C Patel
Division of Bipolar Disorders Research, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267 0004, USA
Biol Psychiatry 60:998-1004. 2006..This study used proton magnetic resonance spectroscopy (1H MRS) to identify the in vivo effects of lithium on myo-inositol (mI) concentrations in adolescent bipolar depression...- Body mass indexes and lipid profiles in hospitalized children and adolescents exposed to atypical antipsychoticsNick C Patel
Division of Bipolar Disorders Research, University of Cincinnati College of Medicine, and Department of Psychiatry, Cincinnati Children s Hospital Medical Center, Ohio 45267 0004, USA
J Child Adolesc Psychopharmacol 17:303-11. 2007..The purpose of this study was to examine body mass indexes (BMI) and lipid profiles of children and adolescents hospitalized for a psychiatric illness and exposed to an atypical antipsychotic... - Ethnic differences in maintenance antipsychotic prescription among adolescents with bipolar disorderNick C Patel
Department of Psychiatry, University of Cincinnati, and the General Clinical Research Center and Mental Health Service Line, Cincinnati Veterans Affairs Medical Center, Ohio 45267 0004, USA
J Child Adolesc Psychopharmacol 15:938-46. 2005..The aim of this study was to compare the longitudinal use of psychotropic medications in African-American and Caucasian adolescents with a diagnosis of bipolar disorder following their first psychiatric hospitalization... - Rehospitalization rates of patients with bipolar disorder discharged on a mood stabilizer versus a mood stabilizer plus an atypical or typical antipsychoticNick C Patel
J Behav Health Serv Res 32:438-45. 2005..Long-term prospective studies are needed to better delineate the effectiveness of different pharmacotherapeutic regimens on the long-term treatment outcomes in patients with bipolar disorder... 
Temporal change in N-acetyl-aspartate concentrations in adolescents with bipolar depression treated with lithiumNick C Patel
College of Pharmacy, University of Georgia, Medical College of Georgia, Augusta, Georgia 30912 2450, USA
J Child Adolesc Psychopharmacol 18:132-9. 2008..This proton magnetic resonance spectroscopy (1H MRS) study identified the in vivo effects of lithium on N-acetyl-aspartate (NAA) concentrations in adolescent bipolar depression...- Risk of neuroleptic malignant syndrome in patients with bipolar disorder: a retrospective, population-based case-control studyYan Chen
Department of Pharmacy Practice and Administrative Sciences, School of Pharmacy, University of Cincinnati Medical Center, Ohio 45267 0004, USA
Int J Psychiatry Med 39:439-50. 2009..Current data regarding risk factors of neuroleptic malignant syndrome (NMS) are limited. This study aims to examine factors associated with increased risk of NMS in patients with bipolar disorder... - Glutamatergic effects of divalproex in adolescents with mania: a proton magnetic resonance spectroscopy studyJeffrey R Strawn
University of Cincinnati, College of Medicine, Cincinnati, OH 45267, USA
J Am Acad Child Adolesc Psychiatry 51:642-51. 2012.... - Physician specialty associated with antipsychotic prescribing for youths in the Texas Medicaid programNick C Patel
College of Pharmacy, University of Cincinnati, Cincinnati, Ohio, USA
Med Care 44:87-90. 2006..Future research is necessary to evaluate patient outcomes associated with antipsychotic treatment across different treatment settings... - Risk of cerebrovascular events associated with antidepressant use in patients with depression: a population-based, nested case-control studyYan Chen
Research Associate of Pharmacoepidemiology and Pharmacoeconomics, School of Pharmacy, University of Cincinnati Medical Center, Cincinnati, OH 45267, USA
Ann Pharmacother 42:177-84. 2008..Given the widespread use of antidepressants and the negative consequence of cerebrovascular events (CVEs), an evaluation of the risk of CVEs associated with antidepressants is warranted... - Treatment costs related to bipolar disorder and comorbid conditions among Medicaid patients with bipolar disorderJeff J Guo
Division of Pharmacy Practice and Administrative Sciences, College of Pharmacy and the Institute for the Study of Health, University of Cincinnati Academic Health Center, 3225 Eden Avenue, Cincinnati, OH 45267 0004, USA
Psychiatr Serv 58:1073-8. 2007..This study assessed costs among patients with bipolar disorder for treatment related to bipolar disorder and to comorbid conditions. Risk factors associated with costs were also assessed... - Aripiprazole: a comprehensive review of its pharmacology, clinical efficacy, and tolerabilityAnthony DeLeon
College of Pharmacy, University of Texas at Austin, 1 University Station, Austin, TX 78712-0124, USA
Clin Ther 26:649-66. 2004..Long-term, head-to-head comparisons with other SGAs are needed to establish the effects of chronic administration and the relative safety and efficacy of aripiprazole... - Trends in the use of typical and atypical antipsychotics in children and adolescentsNick C Patel
Department of Pharmacy Practice, University of Cincinnati, USA
J Am Acad Child Adolesc Psychiatry 44:548-56. 2005..Given the limited data with atypical antipsychotics in youths, this emphasizes the need for additional studies of these agents and other treatment modalities in this population... - Antidepressant prophylaxis for poststroke depression: a meta-analysisYan Chen
Pharmacoepidemiology and Pharmacoeconomics, Division of Pharmacy Practice and Administrative Sciences, College of Pharmacy, University of Cincinnati Medical Center, Cincinnati, Ohio 45267 0004, USA
Int Clin Psychopharmacol 22:159-66. 2007.... - Utilization, price, and spending trends for antidepressants in the US Medicaid ProgramYan Chen
Division of Pharmacy Practice and Administrative Sciences, University of Cincinnati College of Pharmacy, 3225 Eden Avenue, Cincinnati, OH 45267 0004, USA
Res Social Adm Pharm 4:244-57. 2008..However, antidepressant utilization and price patterns within this market have not yet been adequately characterized... - Hemorrhagic stroke associated with antidepressant use in patients with depression: does degree of serotonin reuptake inhibition matter?Yan Chen
Division of Pharmacy Practice and Administrative Sciences, University of Cincinnati Medical Center, Cincinnati, OH 45267 0004, USA
Pharmacoepidemiol Drug Saf 18:196-202. 2009..This study aimed to determine whether the degree of serotonin (5-HT) reuptake inhibition affects risk of hemorrhagic stroke associated with antidepressant use in patients with depression... - Trends in antipsychotic use in a Texas medicaid population of children and adolescents: 1996 to 2000Nick C Patel
College of Pharmacy, The University of Texas at Austin, Austin, Texas 78712, USA
J Child Adolesc Psychopharmacol 12:221-9. 2002..Male and female antipsychotic prevalence rates increased during the 5-year period. The increase in total expenditures was related to the increased utilization of atypical antipsychotics... - Atypical neuroleptic malignant syndrome: diagnostic controversies and considerationsLara S Picard
Division of Pharmacy Practice and Administrative Sciences, College of Pharmacy, University of Cincinnati, Cincinnati, OH, USA
Pharmacotherapy 28:530-5. 2008..In patients receiving any antipsychotic, clinicians should carefully evaluate any features of NMS and should not prematurely exclude a diagnosis of NMS in cases where severe rigidity or hyperthermia is not initially apparent... - A retrospective analysis of the short-term effects of olanzapine and quetiapine on weight and body mass index in children and adolescentsNick C Patel
College of Pharmacy, University of Texas at Austin, 78712, USA
Pharmacotherapy 24:824-30. 2004..Further studies are necessary to determine the relative risk, magnitude, and time course of antipsychotic-induced weight gain in this patient population... - Drug adherence: effects of decreased visit frequency on adherence to clozapine therapyNick C Patel
Division of Pharmacy Practice, College of Pharmacy, Department of Psychiatry, College of Medicine, University of Cincinnati, Cincinnati, Ohio, USA
Pharmacotherapy 25:1242-7. 2005.... - Exposure to potentially dangerous drug-drug interactions involving antipsychoticsJeff Jianfei Guo
Division of Pharmacy Practice and Administrative Sciences, College of Pharmacy, University of Cincinnati Medical Center, 3225 Eden Ave, Cincinnati, OH 45267, USA
Psychiatr Serv 63:1080-8. 2012..This study used a large state's Medicaid claims database to examine the proportion of patients exposed to such interactions and the risk factors associated with exposure... - Single-dose pharmacokinetics and safety of ziprasidone in children and adolescentsFloyd R Sallee
Department of Psychiatry, College of Medicine, University of Cincinnati, OH, USA
J Am Acad Child Adolesc Psychiatry 45:720-8. 2006.... - Atomoxetine versus stimulants for treatment of attention deficit/hyperactivity disorderAaron P Gibson
College of Pharmacy, The University of Texas at Austin, 78712, USA
Ann Pharmacother 40:1134-42. 2006..Atomoxetine represents an alternative treatment for ADHD and is unlikely to be associated with abuse; however, long-term safety data are needed to further establish its place in therapy... - A randomized, placebo-controlled study of adjunctive ramelteon in ambulatory bipolar I disorder with manic symptoms and sleep disturbanceSusan L McElroy
aLindner Center of HOPE, Mason, Ohio and University of Cincinnati College of Medicine, Cincinnati, Ohio bDepartment of Psychiatry and Health Behavior, Medical College of Georgia, Augusta, Georgia, USA
Int Clin Psychopharmacol 26:48-53. 2011..Further studies of ramelteon in subgroups of bipolar patients with sleep disturbance, including those with depression or euthymia, seem indicated... - Risk of hepatotoxicity associated with the use of telithromycin: a signal detection using data mining algorithmsYan Chen
Division of Pharmacy Practice and Administrative Sciences, James L Winkle College of Pharmacy, University of Cincinnati Academic Health Center, Cincinnati, OH 45267, USA
Ann Pharmacother 42:1791-6. 2008..With the exception of case reports, limited data are available regarding the risk of hepatotoxicity associated with the use of telithromycin... - Pharmacist screening for depression among patients with diabetes in an urban primary care settingDan E Knight
College of Pharmacy, University of Cincinnati, Cincinnati, OH, USA
J Am Pharm Assoc (2003) 48:518-21. 2008.... - Secretin treatment for autistic disorder: a critical analysisNick C Patel
College of Pharmacy, The University of Texas at Austin, Austin State Hospital, Texas Department of Mental Health and Retardation, 78712, USA
Pharmacotherapy 22:905-14. 2002..A number of controlled clinical trials did not show improvement in autistic symptoms with secretin compared with placebo, possibly indicating no role for the drug in autistic disorder... - Treatment effects of antidepressants in patients with post-stroke depression: a meta-analysisYan Chen
Pharmacoepidemiology and Pharmacoeconomics, Department of Pharmacy Practice and Administrative Sciences, School of Pharmacy, University of Cincinnati Medical Center, Cincinnati, OH 45267 0004, USA
Ann Pharmacother 40:2115-22. 2006..Data regarding the treatment efficacy of antidepressants in patients with PSD are conflicting, and the time-dependent effects of antidepressant treatment in this population are unknown... - Experience with ziprasidoneNick C Patel
J Am Acad Child Adolesc Psychiatry 41:495. 2002 - One-year rehospitalization rates of patients discharged on atypical versus conventional antipsychoticsNick C Patel
Austin State Hospital, Texas Department of Mental Health and Mental Retardation, and the College of Pharmacy of the University of Texas, Austin, Texas 78712, USA
Psychiatr Serv 53:891-3. 2002..Conventional antipsychotics were associated with a lower one-year rehospitalization rate than risperidone or olanzapine... - Adverse event reporting with selective serotonin-reuptake inhibitorsNicole R Hartnell
College of Pharmacy, Dalhousie University, Halifax, Nova Scotia, Canada
Ann Pharmacother 37:1387-91. 2003..Future research is necessary to validate this effect and examine the generalizability to other medications... - Clonidine for attention-deficit/hyperactivity disorder: II. ECG changes and adverse events analysisW Burleson Daviss
University of Texas Health Science Center at San Antonio, TX, USA
J Am Acad Child Adolesc Psychiatry 47:189-98. 2008..To examine the safety and tolerability of clonidine used alone or with methylphenidate in children with attention-deficit/hyperactivity disorder (ADHD)... - Sudden late onset of clozapine-induced agranulocytosisNick C Patel
Austin State Hospital, Texas Department of Mental Health and Mental Retardation, Austin, USA
Ann Pharmacother 36:1012-5. 2002..Patient and treatment system compliance with the registries' protocol regarding WBC monitoring is instrumental in reducing morbidity and mortality rates associated with clozapine use... - Unanswered questions regarding atypical antipsychotic use in aggressive children and adolescentsNick C Patel
The University of Texas at Austin, Texas Department of Mental Health and Mental Retardation, Austin, Texas 78712, USA
J Child Adolesc Psychopharmacol 15:270-84. 2005..Finally, effective interventions require the development and implementation of evidence-based treatment strategies using a multidisciplinary approach...