Research Topics
Genomes and Genes | NURIA M PASTOR-SOLERSummaryAffiliation: University of Pittsburgh Country: USA Publications
| Collaborators
|
Detail Information
Publications
Alkaline pH- and cAMP-induced V-ATPase membrane accumulation is mediated by protein kinase A in epididymal clear cellsNURIA M PASTOR-SOLER
Renal Electrolyte Division, Department of Medicine, University of Pittsburgh School of Medicine, A915 Scaife Hall, 3550 Terrace St, Pittsburgh, PA 15263, USA
Am J Physiol Cell Physiol 294:C488-94. 2008..We conclude that direct stimulation of PKA activity by cAMP is necessary and sufficient for the alkaline pH-induced accumulation of V-ATPase in clear cell apical microvilli...
Regulation of the creatine transporter by AMP-activated protein kinase in kidney epithelial cellsHui Li
Renal Electrolyte Division, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15261, USA
Am J Physiol Renal Physiol 299:F167-77. 2010....
AMP-activated protein kinase inhibits KCNQ1 channels through regulation of the ubiquitin ligase Nedd4-2 in renal epithelial cellsRodrigo Alzamora
Renal Electrolyte Division, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15261, USA
Am J Physiol Renal Physiol 299:F1308-19. 2010..These results indicate that AMPK inhibits KCNQ1 activity by promoting Nedd4-2-dependent channel ubiquitination and retrieval from the plasma membrane...
Vacuolar H+-ATPase apical accumulation in kidney intercalated cells is regulated by PKA and AMP-activated protein kinaseFan Gong
Department of Medicine, Renal Electrolyte Division, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15263, USA
Am J Physiol Renal Physiol 298:F1162-9. 2010..Taken together, our results suggest that in intercalated cells V-ATPase subcellular localization and therefore its activity may be coupled to acid-base status via PKA, and metabolic status via AMPK...
AMP-activated protein kinase inhibits alkaline pH- and PKA-induced apical vacuolar H+-ATPase accumulation in epididymal clear cellsKenneth R Hallows
Renal Electrolyte Division, Dept of Medicine, Scaife A915, 3550 Terrace St, Pittsburgh, PA 15263, USA
Am J Physiol Cell Physiol 296:C672-81. 2009..V-ATPase activity may be coupled to the sensing of acid-base status via PKA and to metabolic status via AMPK...
PKA regulates vacuolar H+-ATPase localization and activity via direct phosphorylation of the a subunit in kidney cellsRodrigo Alzamora
Renal Electrolyte Division, Departments of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15261, USA
J Biol Chem 285:24676-85. 2010..In summary, these results indicate a novel mechanism for the regulation of V-ATPase localization and activity in kidney cells via direct PKA-dependent phosphorylation of the A subunit at Ser-175...
Role of the energy sensor AMP-activated protein kinase in renal physiology and diseaseKenneth R Hallows
Renal Electrolyte Division, Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
Am J Physiol Renal Physiol 298:F1067-77. 2010..A more complete understanding of the AMPK pathway in the kidney offers potential for improved therapies for several renal diseases including diabetic nephropathy, polycystic kidney disease, and ischemia-reperfusion injury...
Galectin-7 modulates the length of the primary cilia and wound repair in polarized kidney epithelial cellsChristine Rondanino
Renal Electrolyte Div, Dept of Medicine, Univ of Pittsburgh School of Medicine, PA 15261, USA
Am J Physiol Renal Physiol 301:F622-33. 2011..We conclude that Gal-7 is selectively targeted to cilia and plays a key role in surface stabilization of glycoconjugates responsible for integrating cilia function with epithelial repair...
Regulation of epithelial Na+ transport by soluble adenylyl cyclase in kidney collecting duct cellsKenneth R Hallows
Renal Electrolyte Division, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA 15621, USA
J Biol Chem 284:5774-83. 2009..In summary, these results suggest that sAC regulates both basal and agonist-stimulated Na(+) reabsorption in the kidney collecting duct, acting to enhance Na(+),K(+)-ATPase activity...
AMP-activated protein kinase regulation of kidney tubular transportNURIA M PASTOR-SOLER
Renal Electrolyte Division, Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA
Curr Opin Nephrol Hypertens 21:523-33. 2012....
SGLT1, a novel cardiac glucose transporter, mediates increased glucose uptake in PRKAG2 cardiomyopathySanjay K Banerjee
Cardiovascular Institute, University of Pittsburgh, Pittsburgh, PA 15213 2582, USA
J Mol Cell Cardiol 49:683-92. 2010..Increased AMPK activity leads to upregulation of SGLT1, which in turn mediates increased cardiac glucose uptake...
