Jose L Pascual

Summary

Affiliation: University of Pennsylvania
Country: USA

Publications

  1. ncbi request reprint Neuroprotective effects of progesterone in traumatic brain injury: blunted in vivo neutrophil activation at the blood-brain barrier
    Jose L Pascual
    Department of Surgery, Division of Traumatology, Surgical Critical Care and Emergency Surgery, Perelman School of Medicine at the University of Pennsylvania, The Trauma Center at Penn, 3400 Spruce Street, Maloney Building, 5th Floor, Philadelphia, PA 19104, USA Electronic address
    Am J Surg 206:840-5; discussion 845-6. 2013
  2. doi request reprint Reduced brain tissue oxygen in traumatic brain injury: are most commonly used interventions successful?
    Jose L Pascual
    Division of Traumatology, Surgical Critical Care and Emergency Surgery, Department of Surgery, 3400 Spruce Street, Philadelphia, PA 19104, USA
    J Trauma 70:535-46. 2011
  3. ncbi request reprint Short simulation training improves objective skills in established advanced practitioners managing emergencies on the ward and surgical intensive care unit
    Jose L Pascual
    Division of Traumatology, Surgical Critical Care and Emergency Surgery, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    J Trauma 71:330-7; discussion 337-8. 2011
  4. doi request reprint Similar effects of hypertonic saline and mannitol on the inflammation of the blood-brain barrier microcirculation after brain injury in a mouse model
    Joshua A Marks
    Department of Surgery, Division of Traumatology, Surgical Critical Care and Emergency Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    J Trauma Acute Care Surg 73:351-7; discussion 357. 2012
  5. ncbi request reprint There's no place like home: boarding surgical ICU patients in other ICUs and the effect of distances from the home unit
    Jose L Pascual
    From the Division of Traumatology, Surgical Critical Care and Emergency Surgery J L P, N W B, D N H, M D, S R A, N D M, C S, C W S, P M R, and Department of Anesthesia and Critical Care B A K, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania and University of Virginia Medical Center M R, Charlottesville, Virginia
    J Trauma Acute Care Surg 76:1096-102. 2014
  6. ncbi request reprint Interhospital transfer: an independent risk factor for mortality in the surgical intensive care unit
    Katherine R Arthur
    Department of Surgery, Weill Cornell School of Medicine, New York, New York, USA
    Am Surg 79:909-13. 2013
  7. doi request reprint Factors associated with mortality and brain injury after falls from the standing position
    Babak Sarani
    Division of Traumatology and Surgical Critical Care, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    J Trauma 67:954-8. 2009
  8. ncbi request reprint Hypertonic saline resuscitation of hemorrhagic shock does not decrease in vivo neutrophil interactions with endothelium in the blood-brain microcirculation
    Wanfeng Gong
    Division of Traumatology, Surgical Critical Care and Emergency Surgery, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    J Trauma 71:275-81; discussion 281-2. 2011
  9. pmc Mineralocorticoid deficiency in hemorrhagic shock
    Nikolai S Tolstoy
    Penn State Hershey College of Medicine, Hershey, Pennsylvania, USA
    J Surg Res 180:232-7. 2013
  10. ncbi request reprint Resuscitation of hypotensive head-injured patients: is hypertonic saline the answer?
    Jose L Pascual
    Division of Traumatology and Surgical Critical Care, Department of Surgery, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    Am Surg 74:253-9. 2008

Collaborators

Detail Information

Publications14

  1. ncbi request reprint Neuroprotective effects of progesterone in traumatic brain injury: blunted in vivo neutrophil activation at the blood-brain barrier
    Jose L Pascual
    Department of Surgery, Division of Traumatology, Surgical Critical Care and Emergency Surgery, Perelman School of Medicine at the University of Pennsylvania, The Trauma Center at Penn, 3400 Spruce Street, Maloney Building, 5th Floor, Philadelphia, PA 19104, USA Electronic address
    Am J Surg 206:840-5; discussion 845-6. 2013
    ..We hypothesized that PRO reduces edema by blocking polymorphonuclear (PMN) interactions with endothelium (EC) in the blood-brain barrier (BBB)...
  2. doi request reprint Reduced brain tissue oxygen in traumatic brain injury: are most commonly used interventions successful?
    Jose L Pascual
    Division of Traumatology, Surgical Critical Care and Emergency Surgery, Department of Surgery, 3400 Spruce Street, Philadelphia, PA 19104, USA
    J Trauma 70:535-46. 2011
    ..We sought to identify the most common interventions used in episodes of compromised PbtO2 and to analyze which were effective...
  3. ncbi request reprint Short simulation training improves objective skills in established advanced practitioners managing emergencies on the ward and surgical intensive care unit
    Jose L Pascual
    Division of Traumatology, Surgical Critical Care and Emergency Surgery, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    J Trauma 71:330-7; discussion 337-8. 2011
    ..We hypothesized that human patient simulator-based training would improve surgical ICU APs' skills at managing medical crises...
  4. doi request reprint Similar effects of hypertonic saline and mannitol on the inflammation of the blood-brain barrier microcirculation after brain injury in a mouse model
    Joshua A Marks
    Department of Surgery, Division of Traumatology, Surgical Critical Care and Emergency Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    J Trauma Acute Care Surg 73:351-7; discussion 357. 2012
    ..We hypothesized that HTS, as compared with MTL, would more greatly reduce PMN-EC interactions, thereby reducing BBB permeability and tissue edema after simulated TBI...
  5. ncbi request reprint There's no place like home: boarding surgical ICU patients in other ICUs and the effect of distances from the home unit
    Jose L Pascual
    From the Division of Traumatology, Surgical Critical Care and Emergency Surgery J L P, N W B, D N H, M D, S R A, N D M, C S, C W S, P M R, and Department of Anesthesia and Critical Care B A K, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania and University of Virginia Medical Center M R, Charlottesville, Virginia
    J Trauma Acute Care Surg 76:1096-102. 2014
    ..We hypothesized that surgical ICU patients experience more complications when boarding in an overflow ICU and that the frequency of these complications are greatest in boarders farthest from the home unit (HU)...
  6. ncbi request reprint Interhospital transfer: an independent risk factor for mortality in the surgical intensive care unit
    Katherine R Arthur
    Department of Surgery, Weill Cornell School of Medicine, New York, New York, USA
    Am Surg 79:909-13. 2013
    ..Interhospital transfer is an independent risk factor for mortality in the SICU population; this risk is unevenly distributed through service lines. Further efforts to determine the cause of this association are warranted...
  7. doi request reprint Factors associated with mortality and brain injury after falls from the standing position
    Babak Sarani
    Division of Traumatology and Surgical Critical Care, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    J Trauma 67:954-8. 2009
    ..The purpose of the current study was to assess risk factors associated with brain injury and death after fall from the standing position only...
  8. ncbi request reprint Hypertonic saline resuscitation of hemorrhagic shock does not decrease in vivo neutrophil interactions with endothelium in the blood-brain microcirculation
    Wanfeng Gong
    Division of Traumatology, Surgical Critical Care and Emergency Surgery, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    J Trauma 71:275-81; discussion 281-2. 2011
    ..We hypothesized that resuscitation of hemorrhagic shock with HTS would blunt brain in vivo PMN-EC interactions...
  9. pmc Mineralocorticoid deficiency in hemorrhagic shock
    Nikolai S Tolstoy
    Penn State Hershey College of Medicine, Hershey, Pennsylvania, USA
    J Surg Res 180:232-7. 2013
    ..We also hypothesized that MD in these patients would be associated with increased length of stay, hypotension, fluid requirements, and acute kidney injury (AKI)...
  10. ncbi request reprint Resuscitation of hypotensive head-injured patients: is hypertonic saline the answer?
    Jose L Pascual
    Division of Traumatology and Surgical Critical Care, Department of Surgery, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    Am Surg 74:253-9. 2008
    ..Institutional use of HTS in STBI can be safely implemented in a center caring for neurotrauma patients. HTS infusion in hypotensive STBI reduces ICP and raises CPP. Brain tissue oxygenation tends to improve after HTS infusion...
  11. doi request reprint Clinical emergencies and outcomes in patients admitted to a surgical versus medical service
    Babak Sarani
    Department of Surgery, Division of Traumatology and Surgical Critical Care, University of Pennsylvania, United States
    Resuscitation 82:415-8. 2011
    ..The purpose of this study was to compare differences in triggers for RRS activation, interventions, and outcomes in patients on medical and surgical services...
  12. ncbi request reprint Practitioner perceptions of trauma video review
    Leah Davis
    Department of Nursing, Hospital of the University of Pennsylvania, Philadelphia, USA
    J Trauma Nurs 20:150-4. 2013
    ..We examined perceptions of educational value and anxiety associated with being reviewed in TVR...
  13. doi request reprint Penetrating trauma in urban women: patterns of injury and violence
    Christina L Jacovides
    Division of Traumatology, Surgical Critical Care and Emergency Surgery, Department of Surgery, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania 19104, USA
    J Surg Res 184:592-8. 2013
    ..We hypothesized that the nature of penetrating injury differs significantly by gender and that these injuries in women are associated with important psychosocial and environmental factors...
  14. ncbi request reprint Hyperbaric oxygen therapy in necrotizing soft tissue infections
    Paul R Massey
    University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    J Surg Res 177:146-51. 2012
    ..Despite this, the efficacy of HBO remains unclear. We hypothesized that HBO would have no effect on mortality or amputation rates...