Anil V Parwani

Summary

Affiliation: University of Pittsburgh
Country: USA

Publications

  1. pmc Increased cancer cell proliferation in prostate cancer patients with high levels of serum folate
    Jeffrey J Tomaszewski
    Department of Urology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    Prostate 71:1287-93. 2011
  2. pmc Primary bladder adenocarcinoma versus metastatic colorectal adenocarcinoma: a persisting diagnostic challenge
    Somak Roy
    Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA 15232, USA
    Diagn Pathol 7:151. 2012
  3. pmc Synchronous primary carcinoid tumor and primary adenocarcinoma arising within mature cystic teratoma of horseshoe kidney: a unique case report and review of the literature
    Henry B Armah
    Department of Pathology, Presbyterian Shadyside Hospital, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
    Diagn Pathol 4:17. 2009
  4. pmc Xp11.2 translocation renal cell carcinoma occurring during pregnancy with a novel translocation involving chromosome 19: a case report with review of the literature
    Henry B Armah
    Department of Pathology, Presbyterian Shadyside Hospital, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
    Diagn Pathol 4:15. 2009
  5. pmc An informatics model for tissue banks--lessons learned from the Cooperative Prostate Cancer Tissue Resource
    Ashokkumar A Patel
    Department of Pathology, Center for Pathology Informatics, Benedum Oncology Informatics Center, University of Pittsburgh, Pittsburgh, PA, USA
    BMC Cancer 6:120. 2006
  6. doi request reprint Primary cardiac osteosarcoma with recurrent episodes and unusual patterns of metastatic spread
    Anil V Parwani
    Department of Pathology, University of Pittsburgh Medical Center Shadyside, Pittsburgh, PA 15232, USA
    Cardiovasc Pathol 17:413-7. 2008
  7. pmc Immunohistochemical staining of radixin and moesin in prostatic adenocarcinoma
    Tanner L Bartholow
    Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    BMC Clin Pathol 11:1. 2011
  8. ncbi request reprint Immunohistochemical staining of precursor forms of prostate-specific antigen (proPSA) in metastatic prostate cancer
    Anil V Parwani
    Division of Pathology Informatics and Genito Urinary Pathology, Univeristy of Pittsburgh Medical Center Shadyside Hospital, Department of Pathology, Pittsburgh, PA 15232, USA
    Am J Surg Pathol 30:1231-6. 2006
  9. pmc National Mesothelioma Virtual Bank: a standard based biospecimen and clinical data resource to enhance translational research
    Waqas Amin
    Department of Biomedical Informatics, University of Pittsburgh, PA, USA
    BMC Cancer 8:236. 2008
  10. doi request reprint Initial experience with a novel pre-sign-out quality assurance tool for review of random surgical pathology diagnoses in a subspecialty-based university practice
    Scott R Owens
    Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    Am J Surg Pathol 34:1319-23. 2010

Detail Information

Publications96

  1. pmc Increased cancer cell proliferation in prostate cancer patients with high levels of serum folate
    Jeffrey J Tomaszewski
    Department of Urology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    Prostate 71:1287-93. 2011
    ....
  2. pmc Primary bladder adenocarcinoma versus metastatic colorectal adenocarcinoma: a persisting diagnostic challenge
    Somak Roy
    Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA 15232, USA
    Diagn Pathol 7:151. 2012
    ..This study attempted to distinguish primary bladder adenocarcinoma (PBA) from metastatic colonic adenocarcinomas (MCA), which is a difficult diagnostic and clinical problem...
  3. pmc Synchronous primary carcinoid tumor and primary adenocarcinoma arising within mature cystic teratoma of horseshoe kidney: a unique case report and review of the literature
    Henry B Armah
    Department of Pathology, Presbyterian Shadyside Hospital, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
    Diagn Pathol 4:17. 2009
    ....
  4. pmc Xp11.2 translocation renal cell carcinoma occurring during pregnancy with a novel translocation involving chromosome 19: a case report with review of the literature
    Henry B Armah
    Department of Pathology, Presbyterian Shadyside Hospital, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
    Diagn Pathol 4:15. 2009
    ..2 translocation RCCs in adult patients with aggressive clinical course, this adult case occurring during pregnancy with a novel translocation involving chromosome 19 followed an indolent clinical course...
  5. pmc An informatics model for tissue banks--lessons learned from the Cooperative Prostate Cancer Tissue Resource
    Ashokkumar A Patel
    Department of Pathology, Center for Pathology Informatics, Benedum Oncology Informatics Center, University of Pittsburgh, Pittsburgh, PA, USA
    BMC Cancer 6:120. 2006
    ..Here we describe the CPCTR information management system architecture, common data element (CDE) development, query interfaces, data curation, and quality control...
  6. doi request reprint Primary cardiac osteosarcoma with recurrent episodes and unusual patterns of metastatic spread
    Anil V Parwani
    Department of Pathology, University of Pittsburgh Medical Center Shadyside, Pittsburgh, PA 15232, USA
    Cardiovasc Pathol 17:413-7. 2008
    ..One year later, the patient presented with recurrent high-grade sarcoma in the soft tissue of the left chest wall. We herein present the spectrum of histological findings and molecular genotyping data...
  7. pmc Immunohistochemical staining of radixin and moesin in prostatic adenocarcinoma
    Tanner L Bartholow
    Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    BMC Clin Pathol 11:1. 2011
    ..abstract:..
  8. ncbi request reprint Immunohistochemical staining of precursor forms of prostate-specific antigen (proPSA) in metastatic prostate cancer
    Anil V Parwani
    Division of Pathology Informatics and Genito Urinary Pathology, Univeristy of Pittsburgh Medical Center Shadyside Hospital, Department of Pathology, Pittsburgh, PA 15232, USA
    Am J Surg Pathol 30:1231-6. 2006
    ..A panel of markers, including proPSA, should be performed when metastatic prostate carcinoma is in the differential diagnosis...
  9. pmc National Mesothelioma Virtual Bank: a standard based biospecimen and clinical data resource to enhance translational research
    Waqas Amin
    Department of Biomedical Informatics, University of Pittsburgh, PA, USA
    BMC Cancer 8:236. 2008
    ..The National Mesothelioma Virtual Bank is an initiative which collects annotated datasets relevant to human mesothelioma to develop an enterprising biospecimen resource to fulfill researchers' need...
  10. doi request reprint Initial experience with a novel pre-sign-out quality assurance tool for review of random surgical pathology diagnoses in a subspecialty-based university practice
    Scott R Owens
    Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    Am J Surg Pathol 34:1319-23. 2010
    ..The tool is a useful quality assurance instrument and its prospective nature allows for the potential prevention of some serious errors...
  11. pmc Immunohistochemical profiles of claudin-3 in primary and metastatic prostatic adenocarcinoma
    Tanner L Bartholow
    University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    Diagn Pathol 6:12. 2011
    ....
  12. ncbi request reprint Orthotopic expression of human 15-lipoxygenase (LO)-1 in the dorsolateral prostate of normal wild-type C57BL/6 mouse causes PIN-like lesions
    Malabika Sen
    Department of Urology, University of Pittsburgh and Cancer Institute, PA 15232, USA
    Prostaglandins Other Lipid Mediat 81:1-13. 2006
    ..Thus, our findings demonstrate the effectiveness of this viral system for 15-LO-1 expression studies in tissues...
  13. ncbi request reprint A novel case of concurrent renal tumors: chromophobe renal cell carcinoma and carcinoid tumor of the kidney with brief review of renal neuroendocrine tumors
    Somak Roy
    Department of Pathology, University of Pittsburgh, Pittsburgh, PA 15261, USA
    Int J Surg Pathol 20:531-5. 2012
    ..To the best of the authors' knowledge, this is the first case of 2 morphologically distinct tumors, one chromophobe renal cell carcinoma and the other primary carcinoid tumor in the same kidney...
  14. pmc Renal oncocytoma: a comparative clinicopathologic study and fluorescent in-situ hybridization analysis of 73 cases with long-term follow-up
    Marie Dvorakova
    Department of Pathology, UPMC Shadyside, 5230 Centre Avenue, Pittsburgh, PA 15232, USA
    Diagn Pathol 5:32. 2010
    ..FISH results, even those showing significant chromosomal abnormalities, should not alter the primarily morphology-based diagnosis of RO...
  15. doi request reprint Whole genome SNP arrays as a potential diagnostic tool for the detection of characteristic chromosomal aberrations in renal epithelial tumors
    Federico A Monzon
    Department of Pathology, University of Pittsburgh, Pittsburgh, PA, USA
    Mod Pathol 21:599-608. 2008
    ....
  16. ncbi request reprint Pleomorphic leiomyosarcoma of the adrenal gland: case report and review of the literature
    Sambit K Mohanty
    Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
    Urology 70:591.e5-7. 2007
    ..Clinical management and subsequent follow-up of this patient is presented...
  17. doi request reprint Idiopathic granulomatous orchitis
    Somak Roy
    Department of Pathology, University of Pittsburgh Medical Center, United States
    Pathol Res Pract 207:275-8. 2011
    ..Differential diagnoses include intratubular germ-cell neoplasia, malignant lymphomas, and malakoplakia. Orchiectomy is currently the most appropriate therapy for this condition...
  18. ncbi request reprint Small glandular proliferations on needle biopsies: most common benign mimickers of prostatic adenocarcinoma sent in for expert second opinion
    Mehsati Herawi
    Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Am J Surg Pathol 29:874-80. 2005
    ..Negative or patchy staining for basal cells and positive staining for AMACR may contribute to diagnostic difficulty in these entities...
  19. doi request reprint Chromosome 14q loss defines a molecular subtype of clear-cell renal cell carcinoma associated with poor prognosis
    Federico A Monzon
    Department of Pathology, The Methodist Hospital Research Institute, Houston, TX, USA
    Mod Pathol 24:1470-9. 2011
    ..Further exploration of 8q gain, 14q loss, MYC, HIF1A and EPAS1 (HIF2α) as molecular markers of tumor behavior and prognosis could aid in personalizing medicine for patients with clear-cell renal cell carcinoma...
  20. pmc Diagnostic utility of p63/P501S double sequential immunohistochemical staining in differentiating urothelial carcinoma from prostate carcinoma
    Malini Srinivasan
    Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
    Diagn Pathol 6:67. 2011
    ..Thus far, there have been no previous studies assessing the diagnostic utility of p63 and P501S combined together as a dual immunostain in distinguishing between these two cancers...
  21. ncbi request reprint Urothelial carcinoma with rhabdoid features: report of 6 cases
    Anil V Parwani
    Department of Pathology, University of Pittsburgh Medical Center, PA, USA
    Hum Pathol 37:168-72. 2006
    ..The histological and immunohistochemical findings in this study serve to broaden the morphological spectrum of urothelial carcinomas with prominent rhabdoid features and add further evidence as to their poor prognosis...
  22. doi request reprint Diffuse expression of PAX2 and PAX8 in the cystic epithelium of mixed epithelial stromal tumor, angiomyolipoma with epithelial cysts, and primary renal synovial sarcoma: evidence supporting renal tubular differentiation
    Matthew Karafin
    Department of Pathology, The Johns Hopkins Medical Institutions, 401 N Broadway, Baltimore, MD 21231 2410, USA
    Am J Surg Pathol 35:1264-73. 2011
    ..Whether this complex epithelium represents entrapped or neoplastic renal tubular epithelium remains an open question...
  23. doi request reprint Fine needle aspiration biopsy of renal mucinous tubular and spindle cell carcinoma: report of two cases
    Deborah A Marks-Jones
    Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
    Diagn Cytopathol 38:51-5. 2010
    ..These cytomorphologic, immunophenotypic, and cytogenetic features were helpful for including this entity in the differential diagnosis of renal cell carcinomas...
  24. doi request reprint Glomus tumor of the kidney: case report and literature review
    Kotaro Sasaki
    Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, Philadelphia 15232, USA
    Int J Surg Pathol 19:393-7. 2011
    ..To date, the tumor has followed a benign course without evidence of local recurrence or metastasis...
  25. pmc An informatics supported web-based data annotation and query tool to expedite translational research for head and neck malignancies
    Waqas Amin
    Department of Biomedical Informatics, University of Pittsburgh, Pittsburgh, PA, USA
    BMC Cancer 9:396. 2009
    ....
  26. ncbi request reprint Primitive neuroectodermal tumor arising in a testicular teratoma with retroperitoneal metastasis: report of an interesting case with review of literature
    Sambit K Mohanty
    Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
    Urology 70:812.e7-10. 2007
    ..We report a relatively unusual case of PNET arising in a malignant mixed germ cell tumor in a 35-year-old man...
  27. doi request reprint Papillary renal cell carcinoma with low-grade spindle cell foci: a mimic of mucinous tubular and spindle cell carcinoma
    Pedram Argani
    Department of Pathology, The Johns Hopkins Medical Institutions, Baltimore, MD 21231 2410, USA
    Am J Surg Pathol 32:1353-9. 2008
    ..Fluorescence in situ hybridization analysis effectively separates these morphologically very similar yet genetically distinctive entities...
  28. ncbi request reprint Pleomorphic giant cell adenocarcinoma of the prostate: report of 6 cases
    Anil V Parwani
    Department of Pathology, University of Pittsburgh Medical Center Shadyside, Pittsburgh, PA, USA
    Am J Surg Pathol 30:1254-9. 2006
    ..Our study expands the histology described in prostate cancer to include in very rare cases with prominent pleomorphism and bizarre giant cells. This giant cell component heralds a particularly aggressive clinical outcome...
  29. doi request reprint Nephrogenic adenoma
    Waqas Amin
    Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    Pathol Res Pract 206:659-62. 2010
    ..The possibility of nephrogenic adenoma should always be in the differential diagnosis when evaluating patients with predisposed urinary tract symptoms...
  30. doi request reprint Use of immunohistochemical markers to confirm the presence of vas deferens in vasectomy specimens
    Kotaro Sasaki
    Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA 15232, USA
    Am J Clin Pathol 132:893-8. 2009
    ..Our data show that CD10 and pankeratin can be used to confirm the presence of VD in vasectomy specimens in which the epithelial histologic features are suboptimal...
  31. ncbi request reprint Solid and papillary epithelial neoplasm of the pancreas (SPENP): observation of "Chinese character" morphology on fine-needle aspiration (FNA)
    Anil V Parwani
    Department of Pathology, The Johns Hopkins Hospital, Baltimore, Maryland 21287, USA
    Diagn Cytopathol 31:164-5. 2004
  32. doi request reprint p16ink4 immunoreactivity is a reliable marker for urothelial carcinoma in situ
    Ming Yin
    Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA 15232, USA
    Hum Pathol 39:527-35. 2008
    ..Alterations of 9p21/chromosome 9 detected by fluorescence in situ hybridization can also be used for diagnostic confirmation and prognostic prediction...
  33. ncbi request reprint Glomus tumor of renal pelvis: a case report and review of the literature
    Mehsati Herawi
    Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, MD 21205 2100, USA
    Hum Pathol 36:299-302. 2005
    ..At initial gross examination, the tumor mimicked a urothelial carcinoma...
  34. doi request reprint Evaluation of whole slide image immunohistochemistry interpretation in challenging prostate needle biopsies
    Jeffrey L Fine
    Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
    Hum Pathol 39:564-72. 2008
    ..With thorough training, careful validation of specific applications, and regular postsignout review of glass IHC slides (eg, quality assurance review), WSI technology can be used for IHC stain interpretation...
  35. pmc Renal cell neoplasms contain shared tumor type-specific copy number variations
    John M Krill-Burger
    Department of Pathology, University of Pittsburgh, Pittsburgh, PA 15232, USA
    Am J Pathol 180:2427-39. 2012
    ..The genomic amplifications/deletions identified herein represent potential diagnostic and/or prognostic biomarkers...
  36. ncbi request reprint Incidentally discovered capillary hemangioma of the prostate
    Benjamin T Ristau
    Department of Urology, University of Pittsburgh School of Medicine, Pennsylvania, USA
    Can J Urol 18:5914-5. 2011
    ..Hemangiomas of genitourinary origin are extremely rare, typically benign vascular tumors. This finding represents the first reported hemangioma within a radical prostatectomy specimen...
  37. pmc The development and deployment of Common Data Elements for tissue banks for translational research in cancer - an emerging standard based approach for the Mesothelioma Virtual Tissue Bank
    Sambit K Mohanty
    Department of Biomedical Informatics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    BMC Cancer 8:91. 2008
    ....
  38. pmc Immunohistochemical analysis of ezrin-radixin-moesin-binding phosphoprotein 50 in prostatic adenocarcinoma
    Tanner L Bartholow
    University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    BMC Urol 11:12. 2011
    ....
  39. doi request reprint Xp11.2 translocation renal cell carcinoma
    Henry B Armah
    Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA
    Arch Pathol Lab Med 134:124-9. 2010
    ..2 translocation RCC with respect to age, clinical behavior, and molecular abnormalities...
  40. doi request reprint Epithelioid sarcoma
    Henry B Armah
    Department of Pathology, University of Pittsburgh Medical Center, PA, USA
    Arch Pathol Lab Med 133:814-9. 2009
    ..Proximal, fibroma-like, and angiomatoid variants have been described. The proximal variant (with larger cells, prominent nucleoli, and rhabdoid changes) is clinically more aggressive...
  41. doi request reprint Mixed epithelial and stromal tumors of the kidney: an overview
    Sambit K Mohanty
    Department of Pathology, Shadyside Hospital, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15232, USA
    Arch Pathol Lab Med 133:1483-6. 2009
    ..Recently a case with translocation t(1;19) has been described. This article provides a brief overview of the current knowledge of mixed epithelial and stromal tumor of the kidney...
  42. pmc Translocator protein blockade reduces prostate tumor growth
    Arlee Fafalios
    Department of Urology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
    Clin Cancer Res 15:6177-84. 2009
    ..The goal of our study was to examine the expression and biological relevance of TSPO in prostate cancer and show that the commonly prescribed benzodiazepine lorazepam, a ligand for TSPO, exhibits anticancer properties...
  43. doi request reprint The development and testing of a laboratory information system-driven tool for pre-sign-out quality assurance of random surgical pathology reports
    Scott R Owens
    Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA
    Am J Clin Pathol 133:836-41. 2010
    ..There has been no significant delay in case turnaround time since implementation. Further assessment of the tool's function after full departmental application is underway...
  44. pmc p63 immunohistochemistry differentiates salivary gland oncocytoma and oncocytic carcinoma from metastatic renal cell carcinoma
    Jonathan B McHugh
    Department of Pathology, University of Michigan Medical Center, 1500 E Medical Center Drive, Ann Arbor, MI 48109 0054, USA
    Head Neck Pathol 1:123-31. 2007
    ..While RCCm, CD10, and vimentin performed adequately, they were significantly less reliable than p63 with both false positives and false negatives...
  45. ncbi request reprint Gliosarcoma: cytopathologic characteristics on fine-needle aspiration (FNA) and intraoperative touch imprint
    Anil V Parwani
    Department of Pathology, The John K Frost Cytopathology Laboratory, The Johns Hopkins Hospital, Baltimore, MD 21287, USA
    Diagn Cytopathol 30:77-81. 2004
    ..A rich arborizing capillary network was evident, as were a high mitosis/karyorrhexis index and foci of necrosis. The glial component consisted of pleomorphic round to oval nuclei and numerous gemistocytes embedded in a fibrillary stroma...
  46. ncbi request reprint Myoepithelial carcinoma arising in a pleomorphic adenoma of the parotid gland: report of a case with cytopathologic findings
    Anil V Parwani
    Department of Pathology, The Johns Hopkins Hospital, Baltimore, Maryland 21287 6940, USA
    Acta Cytol 50:93-6. 2006
    ..Among the various types of carcinomas that can be seen histologically in a CEPA, myoepithelial carcinoma is one of the rarest forms...
  47. ncbi request reprint Atypical teratoid/rhabdoid tumor of the brain: cytopathologic characteristics and differential diagnosis
    Anil V Parwani
    Department of Pathology, The Johns Hopkins Hospital, Baltimore, Maryland 21287, USA
    Cancer 105:65-70. 2005
    ..Although the clinicopathologic and radiologic features of AT/RT have been described previously, to the authors' knowledge the cytomorphologic profile of this tumor has not been studied well...
  48. ncbi request reprint Prostate carcinoma with squamous differentiation: an analysis of 33 cases
    Anil V Parwani
    Department of Pathology, Johns Hopkins Hospital, Baltimore, MD 21231, USA
    Am J Surg Pathol 28:651-7. 2004
    ..Only sporadic cases of prostate carcinomas with squamous differentiation have been reported...
  49. ncbi request reprint Pathologic quiz case: a 35-year-old man with hematuria. Paraganglioma involving the prostate
    Anil V Parwani
    Department of Pathology, The Johns Hopkins Hospital, Baltimore, MD 21231, USA
    Arch Pathol Lab Med 128:e104-6. 2004
  50. ncbi request reprint Metastatic bronchioloalveolar carcinoma presenting as a solitary thyroid nodule: report of a case with fine-needle aspiration cytopathology
    Anil V Parwani
    Department of Pathology, The Johns Hopkins Hospital, Baltimore, Maryland 21287, USA
    Diagn Cytopathol 31:43-7. 2004
    ..In a patient with known primary neoplasm, the differential diagnosis of a thyroid nodule should always include a metastatic lesion along with primary neoplasia...
  51. ncbi request reprint Metastatic malignant melanoma in liver aspirate: cytomorphologic distinction from hepatocellular carcinoma
    Anil V Parwani
    Department of Pathology, The Johns Hopkins Hospital, Baltimore, Maryland 21287 6940, USA
    Diagn Cytopathol 30:247-50. 2004
    ..In selected cases, IPOX studies were critical in arriving at the correct diagnosis...
  52. doi request reprint Central pathology review for phase III clinical trials: the enabling effect of virtual microscopy
    Pawel Mroz
    Department of Pathology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, USA
    Arch Pathol Lab Med 137:492-5. 2013
    ..The potential of CPR in clinical trials was recognized as early as in the 1960s and quickly became embedded as an integral part of many clinical trials since...
  53. doi request reprint Adenocarcinoma of the urinary bladder
    Somak Roy
    Department of Pathology, University of Pittsburgh Medical Center, Pennsylvania 15261, USA
    Arch Pathol Lab Med 135:1601-5. 2011
    ..Clinical, imaging, histologic, and immunohistochemical correlation should be done while rendering this diagnosis, as prognosis and therapeutic options for primary versus metastatic adenocarcinoma vary widely...
  54. doi request reprint Micropapillary urothelial carcinoma: clinico-pathologic review
    Aleksandr M Perepletchikov
    University of Pittsburgh Medical Center, Mercy Hospital, Department of Laboratory Medicine, 1400 Locust Street, Pittsburgh, PA 15219, USA
    Pathol Res Pract 205:807-10. 2009
    ..The current most generally favored treatment option for all patients who present with MPC is immediate radical cystectomy...
  55. pmc Conditional expression of human 15-lipoxygenase-1 in mouse prostate induces prostatic intraepithelial neoplasia: the FLiMP mouse model
    Uddhav P Kelavkar
    Department of Urology and Cancer Institute, University of Pittsburgh, Pittsburgh, PA, USA
    Neoplasia 8:510-22. 2006
    ..The FLiMP mouse model should also be useful in crosses with other GEM models to further define the combinations of molecular alterations necessary for PCa progression...
  56. pmc Deficiency of DNA repair nuclease ERCC1-XPF promotes prostate cancer progression in a tissue recombination model
    Derek J Matoka
    Department of Urology, University of Pittsburgh, Pittsburgh, PA, USA
    Prostate 72:1214-22. 2012
    ..We examined the effect of Ercc1 deletion in the development of prostate cancer in a prostate recapitulation model as Ercc1 deficient mice die within four weeks of birth...
  57. doi request reprint Tumor-to-tumor metastasis: case report of a pulmonary adenocarcinoma metastatic to a clear cell renal cell carcinoma
    Nidhi Aggarwal
    Department of Pathology, University of Pittsburgh Medical Center Shadyside, Pittsburgh, PA, USA
    Pathol Res Pract 208:50-2. 2012
    ..The physiopathological mechanisms making clear cell renal cell carcinoma an avid recipient of a metastatic carcinoma have been speculated upon, but are still unknown...
  58. pmc Prostatic adenocarcinoma metastatic to pleomorphic liposarcoma, a "collision phenomenon": report of a case with review of pelvic collision tumors
    Somak Roy
    Department of Pathology, University of Pittsburgh Medical Center, A615, Scaife Hall, 3550 Terrace Street, Pittsburgh, PA 15261, USA
    Patholog Res Int 2011:173541. 2011
    ..To the best of our knowledge, this is the second case reported till date. We present the challenges encountered in the diagnosis of this case and review of pelvic collision tumors...
  59. pmc Availability and quality of paraffin blocks identified in pathology archives: a multi-institutional study by the Shared Pathology Informatics Network (SPIN)
    Ashokkumar A Patel
    Department of Pathology, Center for Pathology Informatics, Benedum Oncology Informatics Center, University of Pittsburgh, Pittsburgh, PA, USA
    BMC Cancer 7:37. 2007
    ..This paper examines if tissue blocks, identified by localized computer searches at participating institutions, can be retrieved in adequate quantity and quality to support medical researchers...
  60. ncbi request reprint Particle disease: cytopathologic findings of an unusual case
    Anil V Parwani
    Department of Pathology, The Johns Hopkins Hospital, Baltimore, Maryland 21287, USA
    Diagn Cytopathol 31:259-62. 2004
    ..Numerous multinucleated giant cells were observed as well. Differential diagnosis includes primary or metastatic clear-cell tumors...
  61. ncbi request reprint Polyoma virus-associated cellular changes in the urine and bladder biopsy samples: a cytohistologic correlation
    Mehsati Herawi
    Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Am J Surg Pathol 30:345-50. 2006
    ..63%; 2 of 316 tumor spots), which further illustrates the patchy and focal presence of virion containing cells. p53 staining in these two spots was also patchy and confined to rare nuclei...
  62. ncbi request reprint The importance of pathology informatics in translational research
    Sambit K Mohanty
    Department of Biomedical Informatics, University of Pittsburgh School of Medicine, Pittsburgh, PA 15232, USA
    Adv Anat Pathol 14:320-2. 2007
    ..Herein, we describe the various bioinformatics tools used to support translational research at the University of Pittsburgh Medical Center...
  63. doi request reprint Cytomorphology of lymphoepithelioma-like carcinoma of the urinary bladder: report of two cases
    Guoping Cai
    Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15232, USA
    Diagn Cytopathol 36:600-3. 2008
    ..The differential diagnosis included otherwise typical high-grade urothelial carcinoma, reactive urothelial cells and rarely large cell lymphoma. The rarity of the tumor cells may impose a diagnostic challenge in urine specimen...
  64. ncbi request reprint Sarcomatoid urothelial carcinoma with choriocarcinomatous features: first report of an unusual case
    Henry B Armah
    Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA
    Urology 70:812.e11-4. 2007
    ..This is the first report, to our knowledge, indicating both sarcomatoid and choriocarcinomatous features in a conventional urothelial carcinoma of the bladder...
  65. doi request reprint Perivascular epithelioid cell tumor
    Henry B Armah
    Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    Arch Pathol Lab Med 133:648-54. 2009
    ..Since few malignant cases have been reported, firm criteria for malignancy have yet to be established. This review focuses on the perivascular epithelioid cell tumors-not otherwise specified subset...
  66. ncbi request reprint Solitary fibrous tumor of the thyroid: cytopathologic findings and differential diagnosis
    Anil V Parwani
    Department of Pathology, The Johns Hopkins Hospital, Baltimore, Maryland 21287 6940, USA
    Diagn Cytopathol 28:213-6. 2003
    ..After the FNA diagnosis of "thyroid neoplasm" was made, the patient underwent a near-total thyroidectomy, which revealed a SFT. Differential diagnosis of spindle cell lesions in thyroid is also presented...
  67. ncbi request reprint Urinary bladder biopsy with denuded mucosa: denuding cystitis-cytopathologic correlates
    Anil V Parwani
    Department of Pathology, The Johns Hopkins Hospital, Baltimore, Maryland 21287, USA
    Diagn Cytopathol 30:297-300. 2004
    ..A cytologic diagnosis of high-grade urothelial carcinoma in these cases leads to a timely clinical intervention for optimal patient management...
  68. pmc Synoptic tool for reporting of hematological and lymphoid neoplasms based on World Health Organization classification and College of American Pathologists checklist
    Sambit K Mohanty
    Department of Biomedical Informatics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    BMC Cancer 7:144. 2007
    ..This ensures the pathologists make note of these findings in their reports, thereby improving the quality and uniformity of information in the pathology reports...
  69. ncbi request reprint Pathologic quiz case: a 15-year-old adolescent girl with supraclavicular lymphadenopathy and pleural and pericardial effusions
    Anil V Parwani
    Department of Pathology, The Johns Hopkins Hospital, Baltimore, MD 21287, USA
    Arch Pathol Lab Med 127:e288-90. 2003
  70. ncbi request reprint Immunohistochemical and genetic analysis of non-small cell and small cell gallbladder carcinoma and their precursor lesions
    Anil V Parwani
    Department of Pathology, The Johns Hopkins Hospital, Baltimore, Maryland 21231 2410, USA
    Mod Pathol 16:299-308. 2003
    ..It is noteworthy that all of these alterations occur at the level of carcinoma in situ...
  71. ncbi request reprint Mollaret's meningitis: cytopathologic analysis of fourteen cases
    Theresa Y Chan
    Department of Pathology, John K Frost Cytopathology Laboratory, The Johns Hopkins Hospital, Baltimore, Maryland, USA
    Diagn Cytopathol 28:227-31. 2003
    ..the latter, although nonspecific, provides an accurate diagnosis. The differential diagnosis includes various degenerative, inflammatory/infectious, and lymphoproliferative disorders of the central nervous system...
  72. pmc Immunohistochemical staining of slit2 in primary and metastatic prostatic adenocarcinoma
    Tanner L Bartholow
    University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    Transl Oncol 4:314-20. 2011
    ....
  73. pmc Use of a laboratory information system driven tool for pre-signout quality assurance of random cytopathology reports
    Sonal Kamat
    Department of Pathology, University of Pittsburgh Medical Center, Shadyside Hospital, Pittsburgh, PA, USA
    J Pathol Inform 2:42. 2011
    ..The aim of this study was to review our experience and the effectiveness of this novel PQAT tool in cytology...
  74. ncbi request reprint Pathologic quiz case: a 50-year-old man with a lung mass, respiratory distress, and pericardial effusion. Metastatic clear cell sarcoma (malignant melanoma of soft parts)
    Anil V Parwani
    Department of Pathology, The Johns Hopkins Hospital, Baltimore, MD 21287, USA
    Arch Pathol Lab Med 128:e56-7. 2004
  75. doi request reprint Effectiveness of random and focused review in detecting surgical pathology error
    Stephen S Raab
    Department of Pathology, University of Colorado Denver, Aurora, CO 80045, USA
    Am J Clin Pathol 130:905-12. 2008
    ..36%) and 12 (3.2%), respectively (P < .001). Focused review detects a higher proportion of errors and may be more effectively used for design of error reduction initiatives...
  76. doi request reprint Xanthogranulomatous pyelonephritis
    Li Li
    Department of Pathology, Albany Medical College, 47 New Scotland Ave, Albany, NY 12208, USA
    Arch Pathol Lab Med 135:671-4. 2011
    ..Both antibiotics and surgery can be treatment options depending on the patient's disease status...
  77. ncbi request reprint Echinococcal cyst of the liver
    Anil V Parwani
    Department of Pathology, The Johns Hopkins Hospital, Baltimore, Maryland 21287, USA
    Diagn Cytopathol 31:111-2. 2004
  78. ncbi request reprint Prostatic adenocarcinoma metastases mimicking small cell carcinoma on fine-needle aspiration
    Anil V Parwani
    The John K Frost Cytopathology Laboratory, Department of Pathology, The Johns Hopkins Hospital, Baltimore, Maryland 21287 6417, USA
    Diagn Cytopathol 27:75-9. 2002
    ..An accurate diagnosis of these lesions as PA metastases is essential for effective, timely treatment and therapeutic design...
  79. ncbi request reprint Pathologic quiz case: a 30-year-old man with lower abdominal and back pain. Anaplastic large cell lymphoma (Ki-1 lymphoma) of the pancreas
    Anil V Parwani
    Department of Pathology, The Johns Hopkins Hospital, Baltimore, MD 21287, USA
    Arch Pathol Lab Med 128:e179-80. 2004
  80. ncbi request reprint Cytopathologic findings in breast masses in men with HIV infection
    Elizabeth A Allen
    Department of Pathology, Johns Hopkins Hospital, Path 406, 600 North Wolfe Street, Baltimore, Maryland 21287, USA
    Acta Cytol 47:183-7. 2003
    ..To report the cytologic findings on 15 men with HIV infection who presented with breast masses and underwent fine needle aspiration (FNA)...
  81. pmc Estrogen receptor beta functions through nongenomic mechanisms in lung cancer cells
    Guangfeng Zhang
    University of Pittsburgh Cancer Institute, Hillman Cancer Center, Pittsburgh, Pennsylvania 15213, USA
    Mol Endocrinol 23:146-56. 2009
    ..In conclusion, our results suggest that that proliferative effects of estrogen in lung cancer cells is mediated primarily, if not exclusively, by the nongenomic action of ERbeta...
  82. ncbi request reprint Rhabdoid meningioma: cytopathologic findings in cerebrospinal fluid
    Anil V Parwani
    Department of Pathology, The Johns Hopkins Hospital, Baltimore, Maryland 21287, USA
    Diagn Cytopathol 29:297-9. 2003
    ....
  83. ncbi request reprint Recurrent respiratory papillomatosis: cytopathological findings in an unusual case
    Anil V Parwani
    Department of Pathology, The Johns Hopkins Hospital, Baltimore, Maryland 21287 6417, USA
    Diagn Cytopathol 31:407-12. 2004
    ..To our knowledge, morphological findings of RRP have been reported rarely...
  84. ncbi request reprint Pathologic quiz case: a 52-year-old woman with a liver mass
    Anil V Parwani
    Department of Pathology, The Johns Hopkins Hospital, Baltimore, MD 21287, USA
    Arch Pathol Lab Med 127:631-2. 2003
  85. doi request reprint Spermatocytic seminoma
    Nidhi Aggarwal
    Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA
    Arch Pathol Lab Med 133:1985-8. 2009
    ..It is important to differentiate this condition from its frequent mimics, such as classic seminoma and embryonal carcinoma, because patients with spermatocytic seminoma may not require further treatment after surgery...
  86. ncbi request reprint Use of whole slide imaging in surgical pathology quality assurance: design and pilot validation studies
    Jonhan Ho
    Center for Pathology Informatics, Department of Pathology, University of Pittsburgh Medical Center Pittsburgh, PA 15232, USA
    Hum Pathol 37:322-31. 2006
    ....
  87. doi request reprint Challenges and opportunities in the adoption of College of American Pathologists checklists in electronic format: perspectives and experience of Reporting Pathology Protocols Project (RPP2) participant laboratories
    Lewis A Hassell
    Department of Pathology, University of Oklahoma Health Science Center, Oklahoma City, OK 73104, USA
    Arch Pathol Lab Med 134:1152-9. 2010
    ....
  88. ncbi request reprint Pathologic quiz case: a 54-year-old man with hypertension. Primary high-grade leiomyosarcoma of the IVC
    Anil V Parwani
    Department of Pathology, The Johns Hopkins Hospital, Baltimore, MD 21287, USA
    Arch Pathol Lab Med 127:e423-4. 2003
  89. doi request reprint Heterotopic breast epithelial inclusion of the heart: report of a case
    Kotaro Sasaki
    Department of Pathology, University of Pittsburgh Medical Center, PA 15213, USA
    Am J Surg Pathol 34:1555-9. 2010
    ..Although the heterotopic breast tissue on the skin along the milk line is well recognized, it has not been described to involve internal organs including the heart...
  90. ncbi request reprint Colloid cyst of the third ventricle: cytomorphologic features on stereotactic fine-needle aspiration
    Anil V Parwani
    Department of Pathology, The Johns Hopkins Hospital, Baltimore, Maryland 21287, USA
    Diagn Cytopathol 27:27-31. 2002
    ..Stereotactic FNA of the CC of the third ventricle is an accurate and cost-effective diagnostic modality. Cytomorphology coupled with the radiologic features is sufficiently unique for the diagnosis of this rare pathologic entity...
  91. doi request reprint The Symphony protocol for H&E staining of prostatic adenocarcinoma on needle biopsy: a multicentre analysis of 120 cases
    Adeboye O Osunkoya
    Emory University School of Medicine, Atlanta, Georgia, USA
    Pathology 40:450-6. 2008
    ..The aim of this study was to determine if the Ventana Symphony H&E protocol can improve on the detection of prominent nucleoli in foci of prostate cancer...
  92. doi request reprint Proximal-type epithelioid sarcoma of the scrotum: a difficult diagnosis in an unusual location and review of the literature
    Henry B Armah
    Pathology 40:326-30. 2008
  93. ncbi request reprint Hepatocyte paraffin 1 immunoexpression in esophageal brush samples
    Jun Zhang
    Department of Pathology, The Johns Hopkins Hospital, Baltimore, Maryland 21287, USA
    Cancer 105:304-9. 2005
    ..A cytopathologic diagnosis of IM on esophageal brushings by morphology alone can be difficult. The authors investigated the role of hepatocyte paraffin 1 (Heppar-1) immunostaining as a possible marker of IM in cytologic samples of BE...
  94. ncbi request reprint Keratinized squamous cells in fine needle aspiration of the brain. Cytopathologic correlates and differential diagnosis
    Anil V Parwani
    Departments of Pathology and Neurosurgery, Johns Hopkins Hospital, 600 North Wolfe Street, Baltimore, Maryland 21287, USA
    Acta Cytol 47:325-31. 2003
    ..To analyze the differential diagnosis when keratinized squamous cells are found in a brain aspirate...
  95. ncbi request reprint Diagnostic accuracy and pitfalls in fine-needle aspiration interpretation of Warthin tumor
    Anil V Parwani
    Department of Pathology, The Johns Hopkins Hospital, Baltimore, Maryland 21287, USA
    Cancer 99:166-71. 2003
    ..In this study, the authors analyzed the potential sources of diagnostic errors and overall accuracy of FNA diagnosis of WT...
  96. doi request reprint Lymphoepithelioma-like carcinoma of the urinary bladder
    Kudakwashe R Chikwava
    Pathology 40:310-1. 2008