Research Topics
| Edward E PartridgeSummaryAffiliation: University of Alabama at Birmingham Country: USA Publications
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Detail Information
Publications
The deep South network for cancer control: eliminating cancer disparities through community-academic collaborationEdward E Partridge
Departments of Obstetrics and Gynecology, The University of Alabama at Birmingham, 35233 7333, USA
Fam Community Health 28:6-19. 2005..This article describes the steps necessary to form the network and the process and activities required to establish it as an effective infrastructure for eliminating disparities between Whites and African Americans in the United States...
Results from four rounds of ovarian cancer screening in a randomized trialEdward Partridge
University of Alabama at Birmingham School of Medicine, Birmingham, Alabama 35294, USA
Obstet Gynecol 113:775-82. 2009..To test whether annual screening with transvaginal ultrasonography and CA 125 reduces ovarian cancer mortality...- A higher degree of LINE-1 methylation in peripheral blood mononuclear cells, a one-carbon nutrient related epigenetic alteration, is associated with a lower risk of developing cervical intraepithelial neoplasiaChandrika J Piyathilake
Department of Nutrition Sciences, University of Alabama at Birmingham, Birmingham, Alabama, USA
Nutrition 27:513-9. 2011..The objective of the study was to evaluate LINE-1 methylation as an intermediate biomarker for the effect of folate and vitamin B12 on the occurrence of higher grades of cervical intraepithelial neoplasia (CIN ≥ 2)... - Protective association of MTHFR polymorphism on cervical intraepithelial neoplasia is modified by riboflavin statusChandrika J Piyathilake
University of Alabama at Birmingham, Birmingham, Alabama, USA
Nutrition 23:229-35. 2007..40, 95% confidence interval [CI] 0.21-0.78, P = 0.007). In the present study, we tested whether this protective association is modified by circulating riboflavin status in the same study population... 
A dietary pattern associated with LINE-1 methylation alters the risk of developing cervical intraepithelial neoplasiaChandrika J Piyathilake
Department of Nutrition Sciences, University of Alabama at Birmingham, 1675 University Blvd, Webb 326, Birmingham, AL 35294, USA
Cancer Prev Res (Phila) 5:385-92. 2012..The degree of PBMC L1 methylation may serve as a biomarker for monitoring the effectiveness of dietary modifications needed for reducing the risk of CIN 2+...- A higher degree of methylation of the HPV 16 E6 gene is associated with a lower likelihood of being diagnosed with cervical intraepithelial neoplasiaChandrika J Piyathilake
Department of Nutrition Sciences, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
Cancer 117:957-63. 2011.... - The Deep South Network for cancer control. Building a community infrastructure to reduce cancer health disparitiesNedra Lisovicz
Division of Preventive Medicine, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
Cancer 107:1971-9. 2006..The goal of eliminating cancer health disparities will be pursued in the targeted rural and urban counties in Mississippi and Alabama using Community-Based Participatory Research. Cancer 2006. (c) 2006 American Cancer Society... - A phase II trial of weekly topotecan for patients with secondary platinum-resistant recurrent epithelial ovarian carcinoma following the failure of second-line therapyWhitney A Spannuth
Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, The University of Alabama at Birmingham, AL 35294, USA
Gynecol Oncol 104:591-5. 2007..To determine the response rate, progression-free survival and toxicity associated with weekly topotecan administered to patients with platinum-sensitive recurrent epithelial ovarian (EOC) in the third-line setting... - Lower risk of cervical intraepithelial neoplasia in women with high plasma folate and sufficient vitamin B12 in the post-folic acid fortification eraChandrika J Piyathilake
Department of Nutrition Sciences, University of Alabama at Birmingham, 1675 University Boulevard, Webb 326, Birmingham, AL 35294, USA
Cancer Prev Res (Phila) 2:658-64. 2009.... - Lower red blood cell folate enhances the HPV-16-associated risk of cervical intraepithelial neoplasiaChandrika J Piyathilake
Department of Nutrition Sciences, University of Alabama at Birmingham, Birmingham, Alabama, USA
Nutrition 23:203-10. 2007..In the present study conducted in the same study population, we tested whether circulating folate concentrations modify the risk of cervical intraepithelial neoplasia (CIN) > or =2 associated with specific types of HR-HPV... - Planning and implementation of a participatory evaluation strategy: a viable approach in the evaluation of community-based participatory programs addressing cancer disparitiesIsabel C Scarinci
University of Alabama at Birmingham, Division of Preventive Medicine, Birmingham, AL 35294 4410, USA
Eval Program Plann 32:221-8. 2009..Despite the challenges, we offer a viable approach to evaluation of CBPR programs focusing on cancer disparities... - Reflex human papilloma virus infection testing detects the same proportion of cervical intraepithelial neoplasia grade 2-3 in young versus elderly womenIsam A Eltoum
Department of Pathology, The University of Alabama at Birmingham, Birmingham, Alabama 35233, USA
Cancer 105:194-8. 2005..Because age is an important determinant of the incidence of both ASCUS and HPV infection, the current study was conducted to determine the impact of age on reflex HPV infection test performance... - A lower degree of PBMC L1 methylation is associated with excess body weight and higher HOMA-IR in the presence of lower concentrations of plasma folateChandrika J Piyathilake
the Department of Nutrition Sciences, University of Alabama at Birmingham UAB, Birmingham, Alabama, USA
PLoS ONE 8:e54544. 2013.... - Cancer health disparities: what we have doneNedra Lisovicz
Department of Preventive Medicine, MT 516, 1717 11th Ave. South, Birmingham, AL 35294, USA
Am J Med Sci 335:254-9. 2008 - Folate is associated with the natural history of high-risk human papillomavirusesChandrika J Piyathilake
Departments of Nutrition Sciences, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
Cancer Res 64:8788-93. 2004..Improving folate status in subjects at risk of getting infected or already infected with high-risk HPV may have a beneficial impact in the prevention of cervical cancer... - Predictors of retention of African American women in a walking programMonica L Baskin
UAB Comprehensive Cancer Center, Birmingham, AL 35294 4410, USA
Am J Health Behav 35:40-50. 2011..To predict retention of African American women 6 months after initiating a community walking program... - Cervical cancer prevention: new tools and old barriersIsabel C Scarinci
Division of Preventive Medicine, University of Alabama at Birmingham, Birmingham, Alabama 35294 4410, USA
Cancer 116:2531-42. 2010..The goal was to inform future research and outreach efforts to reduce the burden of cervical cancer in underserved populations... - Assessing the risk of ovarian malignancy in asymptomatic women with abnormal CA 125 and transvaginal ultrasound scans in the prostate, lung, colorectal, and ovarian screening trialEdward E Partridge
University of Alabama at Birmingham, Birmingham, Alabama 35294 3300, USA
Obstet Gynecol 121:25-31. 2013..To estimate the risk of ovarian malignancy among asymptomatic women with abnormal transvaginal ultrasound scans or CA 125 and to provide guidance to physicians managing these women... - Predictors of outcomes for women with cervical carcinomaCharles A Leath
Department of Obstetrics and Gynecology, Division of Gynecology Oncology, University of Alabama at Birmingham, 619 19th Street South, OHB538, Birmingham, AL 35249 7333, USA
Gynecol Oncol 99:432-6. 2005..To determine the impact of race and other factors on the management and outcomes of women treated for cervical cancer in a rural state... - The use of adjuvant radiation therapy in patients with intermediate-risk Stages IC and II uterine corpus cancer: a patient care evaluation study from the American College of Surgeons National Cancer Data BaseJ Michael Straughn
Division of Gynecologic Oncology, University of Alabama, Birmingham, AL 35249, USA
Gynecol Oncol 99:530-5. 2005..To determine the outcomes of patients with intermediate-risk Stages IC and II uterine corpus cancer treated with surgery alone or surgery followed by radiation therapy... - Feasibility of performing chemoprevention trials in women at elevated risk of ovarian carcinoma: initial examination of celecoxib as a chemopreventive agentMack N Barnes
Department of Obstetrics and Gynecology, University of Alabama at Birmingham, Birmingham, AL 35213, USA
Gynecol Oncol 98:376-82. 2005..A pilot study was undertaken to determine the feasibility of examining a COX-2 inhibitor (Celecoxib) as a chemopreventive agent in women at increased risk of ovarian cancer undergoing risk reducing salpingoophorectomy... - Cervical cancer screening preferences among African American women in the Mississippi DeltaAllison G Litton
University of Alabama at Birmingham, Division of Preventive Medicine, Birmingham, AL 35294, USA
J Health Care Poor Underserved 24:46-55. 2013..Alternative strategies must be considered when targeting the under-screened to reduce the burden of cervical cancer... - Role of chemotherapy for patients with recurrent platinum-resistant advanced epithelial ovarian cancer: A cost-effectiveness analysisRodney P Rocconi
Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of Alabama at Birmingham, Birmingham, Alabama 35233, USA
Cancer 107:536-43. 2006..Therefore, the objective in the current study was to assess the cost-effectiveness of salvage chemotherapy for patients with platinum-resistant epithelial ovarian cancer (EOC)... - An examination of acceptability of HPV vaccination among African American women and Latina immigrantsIsabel C Scarinci
Division of Preventive Medicine, University of Alabama at Birmingham, Birmingham, AL 35294 4410, USA
J Womens Health (Larchmt) 16:1224-33. 2007..This study examined the acceptability of preventive human papillomavirus (HPV) vaccination among Latina immigrants and African American women through eight focus groups (n = 55, 28 Latinas and 27 African Americans)... - Indian women with higher serum concentrations of folate and vitamin B12 are significantly less likely to be infected with carcinogenic or high-risk (HR) types of human papillomaviruses (HPVs)Chandrika J Piyathilake
Department of Nutrition Sciences, The University of Alabama at Birmingham UAB, Birmingham, AL, USA
Int J Womens Health 2:7-12. 2010.... - p53 and erbB-2 are not associated in matched cases of primary and metastatic ovarian carcinomasCristina Rodriguez-Burford
Department of Pathology, The University of Alabama at Birmingham, AL 35294, USA
Dis Markers 19:11-7. 2003..Thus, the nuclear accumulation of p53 and immunostaining of p185erbB-2 in the cytoplasm or on the cellular membranes are independent... - Women with polymorphisms of methylenetetrahydrofolate reductase (MTHFR) and methionine synthase (MS) are less likely to have cervical intraepithelial neoplasia (CIN) 2 or 3Olga L Henao
Department of Epidemiology of the University of Alabama at Birmingham, Birmingham, AL, USA
Int J Cancer 113:991-7. 2005..62). We conclude that these polymorphisms in the folate metabolic pathway were associated with a lower likelihood of CIN 2 or 3 in a population exposed to adequate amounts of folate from exposure to food fortification with folic acid... - A pilot study of ovarian cancer chemoprevention using medroxyprogesterone acetate in an avian model of spontaneous ovarian carcinogenesisMack N Barnes
Department of Gynecologic Oncology, University of Alabama at Birmingham, 538 Old Hillman Building, 618 South 20th Street, Birmingham, AL 35233, USA
Gynecol Oncol 87:57-63. 2002..The current histologic findings are consistent with the theory that a reduction of ovulatory events may prevent the development of ovarian adenocarcinoma... - Effects of nonsteroidal anti-inflammatory agents (NSAIDs) on ovarian carcinoma cell lines: preclinical evaluation of NSAIDs as chemopreventive agentsCristina Rodriguez-Burford
Department of Obstetrics and Gynecology, Comprehensive Cancer Center, Biostatistics Unit, The University of Alabama at Birmingham, Birmingham, Alabama 35213, USA
Clin Cancer Res 8:202-9. 2002..The purpose of this study was to investigate the cellular effects of acetylsalicylic acid (ASA), acetaminophen, and a COX-2 inhibitor (NS-398) on the growth of cell lines of human ovarian cancer in vitro... - A Phase I study of combined modality (90)Yttrium-CC49 intraperitoneal radioimmunotherapy for ovarian cancerRonald D Alvarez
Department of Obstetrics, University of Alabama at Birmingham Cancer Center, Birmingham, Alabama 35233, USA
Clin Cancer Res 8:2806-11. 2002..The purpose of this study was to determine the feasibility and maximum tolerated dose of (90)Yttrium-CC49 ((90)Y-CC49) as the radioimmunotherapy (RIT) component of an i.p. combined modality treatment for recurrent ovarian cancer... - Blood-based screening and light based imaging for the early detection and monitoring of ovarian cancer xenograftsTandra R Chaudhuri
Department of Radiology, University of Alabama at Birmingham, JT N333, 619 19th St South, Birmingham, AL 35294 6830, USA
Technol Cancer Res Treat 2:171-80. 2003..This combination will lead to an accurate and widely applicable method for the early detection and monitoring of ovarian cancer, especially in high-risk women.. - The development of a community action plan to reduce breast and cervical cancer disparities between African-American and White womenMona N Fouad
Division of Preventive Medicine, Department of Medicine, University of Alabama at Birmingham, 35294 4410, USA
Ethn Dis 14:S53-60. 2004..Based on these findings, a community-driven CAP was developed. Our results indicate that a coalition of diverse organizations can partner and develop CAPs to improve the health of their communities... - Treatment preferences in recurrent ovarian cancerKristine A Donovan
Department of Psychology, University of Alabama at Birmingham, 35294, USA
Gynecol Oncol 86:200-11. 2002..CONCLUSIONS: The majority of women, independent of a cancer diagnosis, indicated a desire for continuing aggressive treatment, despite poor outcomes. Quality of life was of secondary importance, especially among ovarian cancer patients... - Paradigms for primary prevention of ovarian carcinomaMack N Barnes
Department of Obstetrics and Gynecology, University of Alabama at Birmingham, USA
CA Cancer J Clin 52:216-25. 2002..Continued research efforts toward identification of novel compounds will accelerate the progress of clinical trials in this neglected area of investigation... - Extraovarian peritoneal serous papillary carcinoma: a phase II trial of cisplatin and cyclophosphamide with comparison to a cohort with papillary serous ovarian carcinoma-a Gynecologic Oncology Group StudyJeffrey D Bloss
Department of Obstetrics and Gynecology, Ellis Fischel Cancer Center, University of Missouri Health Sciences Center, Columbia, MO 65203, USA
Gynecol Oncol 89:148-54. 2003.... - Expression of CEA, Tag-72, and Lewis-Y antigen in primary and metastatic lesions of ovarian carcinomaDavid C Chhieng
Department of Pathology, University of Alabama, Birmingham 35249-6823, USA
Hum Pathol 34:1016-21. 2003..CEA (Col-1), due to its low expression and variation in phenotypic expression between primary and metastatic lesions, should be evaluated carefully in metastatic lesions before targeting the CEA antigen with CEA (Col-1)-like antibodies... - Pegylated liposomal doxorubicin consolidation therapy after platinum/paclitaxel-based chemotherapy for suboptimally debulked, advanced-stage epithelial ovarian cancer patientsRodney P Rocconi
University of Alabama at Birmingham, 35233, USA
Oncologist 11:336-41. 2006.... - A cost-effectiveness analysis of chemotherapy for patients with recurrent platinum-sensitive epithelial ovarian cancerAshley S Case
University of Alabama at Birmingham, Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, USA
Gynecol Oncol 105:223-7. 2007..Therefore, our goal was to assess the effectiveness and medical costs of chemotherapy for platinum-sensitive patients with advanced EOC... - Electrical problems? Do you want a general contractor or an electrician?Edward E Partridge
Gynecol Oncol 103:379-80. 2006