Vladimir Parpura

Summary

Affiliation: University of Alabama at Birmingham
Country: USA

Publications

  1. doi request reprint Instrumentation: carbon nanotubes on the brain
    Vladimir Parpura
    University of Alabama, Birmingham, Alabama 35294, USA
    Nat Nanotechnol 3:384-5. 2008
  2. pmc Single molecule measurements of mechanical interactions within ternary SNARE complexes and dynamics of their disassembly: SNAP25 vs. SNAP23
    Vedrana Montana
    Department of Neurobiology, University of Alabama, Birmingham, AL 35294, USA
    J Physiol 587:1943-60. 2009
  3. pmc A Caenorhabditis elegans locomotion phenotype caused by transgenic repeats of the hlh-17 promoter sequence
    Randy F Stout
    Department of Neurobiology, Center for Glial Biology in Medicine, Atomic Force Microscopy and Nanotechnology Laboratories, Civitan International Research Center, Evelyn F McKnight Brain Institute, University of Alabama, Birmingham, Alabama, United States of America
    PLoS ONE 8:e81771. 2013
  4. pmc Micropit: A New Cell Culturing Approach for Characterization of Solitary Astrocytes and Small Networks of these Glial Cells
    William Lee
    Department of Neurobiology, Center for Glial Biology in Medicine, Atomic Force Microscopy and Nanotechnology Laboratories, Civitan International Research Center, Evelyn F McKnight Brain Institute, University of Alabama Birmingham, AL, USA
    Front Neuroeng 1:2. 2008
  5. pmc Micropatterned substrates for studying astrocytes in culture
    William Lee
    Department of Neurobiology, Center for Glial Biology in Medicine, Atomic Force Microscopy and Nanotechnology Laboratories, Civitan International Research Center, Evelyn F McKnight Brain Institute, University of Alabama, Birmingham, AL, USA
    Front Neurosci 3:381-7. 2009
  6. doi request reprint Astrogliopathology: could nanotechnology restore aberrant calcium signalling and pathological astroglial remodelling?
    Vladimir Parpura
    Department of Neurobiology, University of Alabama, Birmingham, AL 35294, USA
    Biochim Biophys Acta 1833:1625-31. 2013
  7. pmc Neuromodulation: selected approaches and challenges
    Vladimir Parpura
    Department of Neurobiology, Center for Glial Biology in Medicine, Atomic Force Microscopy and Nanotechnology Laboratories, Civitan International Research Center, Evelyn F McKnight Brain Institute, University of Alabama, Birmingham, AL 35294, USA
    J Neurochem 124:436-53. 2013
  8. doi request reprint Astroglial amino acid-based transmitter receptors
    Vladimir Parpura
    Department of Neurobiology, Center for Glial Biology in Medicine, Atomic Force Microscopy and Nanotechnology Laboratories, Civitan International Research Center, Evelyn F McKnight Brain Institute, University of Alabama, Birmingham, AL 35294, USA
    Amino Acids 44:1151-8. 2013
  9. pmc Astrocytes revisited: concise historic outlook on glutamate homeostasis and signaling
    Vladimir Parpura
    Department of Neurobiology, University of Alabama, Birmingham, AL 35294 0021, USA
    Croat Med J 53:518-28. 2012
  10. ncbi request reprint The astrocyte excitability brief: from receptors to gliotransmission
    Vladimir Parpura
    Department of Neurobiology, Center for Glial Biology in Medicine, Atomic Force Microscopy and Nanotechnology Laboratories, Civitan International Research Center, Evelyn F McKnight Brain Institute, University of Alabama, Birmingham, AL 35294 0021, United States
    Neurochem Int 61:610-21. 2012

Research Grants

  1. Calcium-dependent glutamate release from astrocytes
    Vladimir Parpura; Fiscal Year: 2007
  2. Calcium-dependent glutamate release from astrocytes
    Vladimir Parpura; Fiscal Year: 2004
  3. Calcium-dependent glutamate release from astrocytes
    Vladimir Parpura; Fiscal Year: 2005
  4. Calcium-dependent glutamate release from astrocytes
    Vladimir Parpura; Fiscal Year: 2006
  5. Glial Biology Gordon Research Conference
    Vladimir Parpura; Fiscal Year: 2007
  6. Calcium-dependent glutamate release from astrocytes
    Vladimir Parpura; Fiscal Year: 2007

Collaborators

Detail Information

Publications48

  1. doi request reprint Instrumentation: carbon nanotubes on the brain
    Vladimir Parpura
    University of Alabama, Birmingham, Alabama 35294, USA
    Nat Nanotechnol 3:384-5. 2008
  2. pmc Single molecule measurements of mechanical interactions within ternary SNARE complexes and dynamics of their disassembly: SNAP25 vs. SNAP23
    Vedrana Montana
    Department of Neurobiology, University of Alabama, Birmingham, AL 35294, USA
    J Physiol 587:1943-60. 2009
    ..Thus, differences in the stability of the two different ternary complexes could underlie some of the SNAP25/23 differential ability to control the exocytotic burst...
  3. pmc A Caenorhabditis elegans locomotion phenotype caused by transgenic repeats of the hlh-17 promoter sequence
    Randy F Stout
    Department of Neurobiology, Center for Glial Biology in Medicine, Atomic Force Microscopy and Nanotechnology Laboratories, Civitan International Research Center, Evelyn F McKnight Brain Institute, University of Alabama, Birmingham, Alabama, United States of America
    PLoS ONE 8:e81771. 2013
    ..We also present evidence that this behavioral phenotype is transpromoter copy number-dependent and manifests early in development and is maintained into adulthood of the worm. ..
  4. pmc Micropit: A New Cell Culturing Approach for Characterization of Solitary Astrocytes and Small Networks of these Glial Cells
    William Lee
    Department of Neurobiology, Center for Glial Biology in Medicine, Atomic Force Microscopy and Nanotechnology Laboratories, Civitan International Research Center, Evelyn F McKnight Brain Institute, University of Alabama Birmingham, AL, USA
    Front Neuroeng 1:2. 2008
    ..Solitary cells in micropit regions can undergo ATP-mediated astrocyte-microglia signaling, demonstrating that this culturing method can also be used to investigate glial-glial interactions in a spatially well-defined microenvironment...
  5. pmc Micropatterned substrates for studying astrocytes in culture
    William Lee
    Department of Neurobiology, Center for Glial Biology in Medicine, Atomic Force Microscopy and Nanotechnology Laboratories, Civitan International Research Center, Evelyn F McKnight Brain Institute, University of Alabama, Birmingham, AL, USA
    Front Neurosci 3:381-7. 2009
    ..Although such a reductionist approach yields some difference in observations between astrocytic properties in culture and in situ, general phenomena discovered in cell culture systems, however, have also been found in vivo...
  6. doi request reprint Astrogliopathology: could nanotechnology restore aberrant calcium signalling and pathological astroglial remodelling?
    Vladimir Parpura
    Department of Neurobiology, University of Alabama, Birmingham, AL 35294, USA
    Biochim Biophys Acta 1833:1625-31. 2013
    ..Recently, they have been used to affect morpho-functional characteristics of astrocytes. This article is part of a Special Issue entitled: 12th European Symposium on Calcium...
  7. pmc Neuromodulation: selected approaches and challenges
    Vladimir Parpura
    Department of Neurobiology, Center for Glial Biology in Medicine, Atomic Force Microscopy and Nanotechnology Laboratories, Civitan International Research Center, Evelyn F McKnight Brain Institute, University of Alabama, Birmingham, AL 35294, USA
    J Neurochem 124:436-53. 2013
    ..With increasing application of nanomaterials in devices for electrical and chemical recording and stimulating in the brain, the era of cellular, and even intracellular, precision neuromodulation will soon be upon us...
  8. doi request reprint Astroglial amino acid-based transmitter receptors
    Vladimir Parpura
    Department of Neurobiology, Center for Glial Biology in Medicine, Atomic Force Microscopy and Nanotechnology Laboratories, Civitan International Research Center, Evelyn F McKnight Brain Institute, University of Alabama, Birmingham, AL 35294, USA
    Amino Acids 44:1151-8. 2013
    ..e. seven transmembrane domain G-protein coupled receptors. In this mini-review, we focus our interest on amino acid-based transmitter receptors on neuroglia, astrocytes in particular...
  9. pmc Astrocytes revisited: concise historic outlook on glutamate homeostasis and signaling
    Vladimir Parpura
    Department of Neurobiology, University of Alabama, Birmingham, AL 35294 0021, USA
    Croat Med J 53:518-28. 2012
    ..Glutamate-activated specific receptors trigger excitatory responses in neurons and astroglia. Here we overview main properties of glutamatergic transmission in neuronal-glial networks and identify some future challenges facing the field...
  10. ncbi request reprint The astrocyte excitability brief: from receptors to gliotransmission
    Vladimir Parpura
    Department of Neurobiology, Center for Glial Biology in Medicine, Atomic Force Microscopy and Nanotechnology Laboratories, Civitan International Research Center, Evelyn F McKnight Brain Institute, University of Alabama, Birmingham, AL 35294 0021, United States
    Neurochem Int 61:610-21. 2012
    ..A cumulative knowledge on astrocytic excitability will aid better understanding of operating procedures in the brain in health and disease...
  11. pmc Neuroglia at the crossroads of homoeostasis, metabolism and signalling: evolution of the concept
    Vladimir Parpura
    Department of Neurobiology, Center for Glial Biology in Medicine, Atomic Force Microscopy and Nanotechnology Laboratories, Civitan International Research Center, Evelyn F McKnight Brain Institute, University of Alabama, Birmingham, AL 35294, USA
    ASN Neuro 4:201-5. 2012
    ..We conclude that the unifying property of otherwise diverse functions of various neuroglial cell sub-types is to maintain brain homoeostasis at different levels, from whole organ to molecular...
  12. pmc Glial cells in (patho)physiology
    Vladimir Parpura
    Department of Neurobiology, Center for Glial Biology in Medicine, Civitan International Research Center, Atomic Force Microscopy and Nanotechnology Laboratories, and Evelyn F McKnight Brain Institute, University of Alabama, Birmingham, Alabama, USA
    J Neurochem 121:4-27. 2012
    ..Highly lethal glial-derived tumors use signaling trickery to coerce normal brain cells to assist tumor invasiveness. This review not only sheds new light on the brain operation in health and disease, but also points to many unknowns...
  13. pmc Gliotransmission: Exocytotic release from astrocytes
    Vladimir Parpura
    Department of Neurobiology, Center for Glial Biology in Medicine, Civitan International Research Center, Atomic Force Microscopy and Nanotechnology Laboratories, and Evelyn F McKnight Brain Institute, University of Alabama, Birmingham, USA
    Brain Res Rev 63:83-92. 2010
    ..It is becoming clear that astrocytes are endowed with elements that qualify them as cells communicating with neurons and other cells within the central nervous system by employing regulated exocytosis...
  14. doi request reprint Molecular form follows function: (un)snaring the SNAREs
    Vladimir Parpura
    Department of Neurobiology, Civitan International Research Center, Evelyn F McKnight Brain Institute, Atomic Force Microscopy and Nanotechnology Laboratories, University of Alabama, Birmingham, AL 35294, USA
    Trends Neurosci 31:435-43. 2008
    ..Consequently, single-molecule techniques promise tremendous opportunities for in vitro investigations of SNARE proteins to improve our understanding of their role in exocytosis...
  15. pmc Regulated exocytosis in astrocytic signal integration
    Vladimir Parpura
    Department of Neurobiology, University of Alabama, Birmingham, AL 35294 0021, USA
    Neurochem Int 57:451-9. 2010
    ..Therefore, we also discuss exocytosis as a delivery mechanism for transporters and receptors to the plasma membrane, where these proteins are involved in astrocytic intercellular signaling...
  16. doi request reprint Ca(2+) sources for the exocytotic release of glutamate from astrocytes
    Vladimir Parpura
    Department of Neurobiology, Center for Glial Biology in Medicine, Civitan International Research Center, Atomic Force Microscopy and Nanotechnology Laboratories, and Evelyn F McKnight Brain Institute, University of Alabama, Birmingham 35294 0021, USA
    Biochim Biophys Acta 1813:984-91. 2011
    ..An understanding of this process in vivo will reveal some of the astrocytic functions in health and disease of the brain. This article is part of a Special Issue entitled: 11th European Symposium on Calcium...
  17. pmc Enhanced Ca(2+)-dependent glutamate release from astrocytes of the BACHD Huntington's disease mouse model
    William Lee
    Department of Neurobiology, University of Alabama, Birmingham, AL 35294, USA
    Neurobiol Dis 58:192-9. 2013
    ..This work identifies a new mechanism in astrocytes that could lead to increased levels of extracellular glutamate in HD and thus may contribute to excitotoxicity in this devastating disease. ..
  18. pmc Mitochondria modulate Ca2+-dependent glutamate release from rat cortical astrocytes
    Reno C Reyes
    Department of Neurobiology, Center for Glial Biology in Medicine, Atomic Force Microscopy and Nanotechnology Laboratories, Civitan International Research Center, Evelyn F McKnight Brain Institute, University of Alabama, Birmingham, Alabama 35294, USA
    J Neurosci 28:9682-91. 2008
    ..These observations suggest that, in addition to the activity of ER and plasma membrane ion channels, mitochondria modulate Ca(2+)(cyt) dynamics in astrocytes and play a role in Ca(2+)-dependent glutamate release from astrocytes...
  19. doi request reprint TRPC1-mediated Ca2+ and Na+ signalling in astroglia: differential filtering of extracellular cations
    Reno C Reyes
    Department of Neurobiology, Center for Glial Biology in Medicine, Atomic Force Microscopy and Nanotechnology Laboratories, Civitan International Research Center, Evelyn F McKnight Brain Institute, University of Alabama, Birmingham, AL 35294, USA
    Cell Calcium 54:120-5. 2013
    ....
  20. pmc The trinity of Ca2+ sources for the exocytotic glutamate release from astrocytes
    Reno C Reyes
    Department of Neurobiology, Center for Glial Biology in Medicine, Atomic Force Microscopy and Nanotechnology Laboratories, Civitan International Research Center, Evelyn F McKnight Brain Institute, University of Alabama, Birmingham, AL 35294, United States
    Neurochem Int 55:2-8. 2009
    ....
  21. pmc Water soluble single-walled carbon nanotubes inhibit stimulated endocytosis in neurons
    Erik B Malarkey
    Department of Neurobiology, Center for Glial Biology in Medicine, Atomic Force Microscopy and Nanotechnology Laboratories, Civitan International Research Center, Evelyn F McKnight Brain Institute, University of Alabama, Birmingham, Alabama 35294, USA
    Nano Lett 8:3538-42. 2008
    ..Here we have determined that SWNTs are able to block stimulated membrane endocytosis in neurons, which could then explain the previously noted extended neurite length...
  22. doi request reprint Chapter 6 - Carbon nanotubes as substrates/scaffolds for neural cell growth
    William Lee
    Department of Neurobiology, Center for Glial Biology in Medicine, Atomic Force Microscopy and Nanotechnology Laboratories, Civitan International Research Center, Evelyn F McKnight Brain Institute, University of Alabama, Birmingham, AL, USA
    Prog Brain Res 180:110-25. 2009
    ..Nonetheless, accumulating data support the use of CNTs as a biocompatible and permissive substrate/scaffold for neural cells and such application holds great potential in biomedicine...
  23. ncbi request reprint Chemically functionalized single-walled carbon nanotube films modulate the morpho-functional and proliferative characteristics of astrocytes
    Manoj K Gottipati
    Departments of Neurobiology and Biomedical Engineering, University of Alabama, Birmingham, Alabama 35294, United States
    Nano Lett 13:4387-92. 2013
    ..Thus, CNT films, as a coating material for electrodes used in brain machine interface, could reduce astrogliosis around the site of implantation. ..
  24. doi request reprint Cell culturing of Caenorhabditis elegans glial cells for the assessment of cytosolic Ca²⁺ dynamics
    Randy F Stout
    Department of Neurobiology, University of Alabama, Birmingham, AL, USA
    Methods Mol Biol 814:153-74. 2012
    ..We describe the combined genetic and fluorescence microscopy approaches for identification of C. elegans glial cells in culture and assessment of their cytosolic Ca(2+) dynamics...
  25. pmc Conductive single-walled carbon nanotube substrates modulate neuronal growth
    Erik B Malarkey
    Department of Neurobiology, Center for Glial Biology in Medicine, Atomic Force Microscopy and Nanotechnology Laboratories, Civitan International Research Center, Evelyn F McKnight Brain Institute, University of Alabama, Birmingham, Alabama 35294, USA
    Nano Lett 9:264-8. 2009
    ....
  26. pmc Immunophilin deficiency augments Ca2+-dependent glutamate release from mouse cortical astrocytes
    Reno C Reyes
    Department of Neurobiology, Center for Glial Biology in Medicine, Atomic Force Microscopy and Nanotechnology Laboratories, Civitan International Research Center, Evelyn F McKnight Brain Institute, University of Alabama, Birmingham, 35294, United States
    Cell Calcium 49:23-34. 2011
    ..These findings point to a possible role of immunophilin signal transduction pathways in astrocytic modulation of neuronal activity at the tripartite synapse...
  27. ncbi request reprint Ternary SNARE complexes in parallel versus anti-parallel orientation: examination of their disassembly using single-molecule force spectroscopy
    Wei Liu
    Department of Neurobiology, Center for Glial Biology in Medicine, Atomic Force Microscopy and Nanotechnology Laboratories, Civitan International Research Center, Evelyn F McKnight Brain Institute, University of Alabama, Birmingham, AL 35294, USA
    Cell Calcium 52:241-9. 2012
    ..We propose a model which considers the geometry for the vesicle approach to the plasma membrane with favorable energies and stability as the basis for preferential usage of the parallel ternary SNARE complex in exocytosis...
  28. doi request reprint Chemically functionalized water-soluble single-walled carbon nanotubes modulate morpho-functional characteristics of astrocytes
    Manoj K Gottipati
    Department of Neurobiology, University of Alabama, Birmingham, Alabama 35294, United States
    Nano Lett 12:4742-7. 2012
    ..Thus, ws-SWCNTs could have more beneficial effects at the injury site than previously thought; by affecting astrocytes, they could provide for a more comprehensive re-establishment of the brain computational power...
  29. doi request reprint Dissociated cell culture for testing effects of carbon nanotubes on neuronal growth
    William Lee
    Department of Neurobiology, Center for Glial Biology in Medicine, Atomic Force Microscopy and Nanotechnology Laboratories, Civitan International Research Center, Evelyn F McKnight Brain Institute, University of Alabama, Birmingham, AL, USA
    Methods Mol Biol 846:261-76. 2012
    ..These combined cell culture and fluorescence microscopy approaches can be successfully used for assessment of the effects that CNTs, as water-soluble agents, have on neuronal cell growth and neurite outgrowth...
  30. doi request reprint Ca2+ entry through TRPC1 channels contributes to intracellular Ca2+ dynamics and consequent glutamate release from rat astrocytes
    Erik B Malarkey
    Department of Neurobiology, Center for Glial Biology in Medicine, Atomic Force Microscopy and Nanotechnology Laboratories, Civitan International Research Center, Evelyn F McKnight Brain Institute, University of Alabama, Birmingham, Alabama 35294, USA
    Glia 56:821-35. 2008
    ..These data indicate that Ca2+ entry through TRPC1 channels contributes to Ca2+ signaling in astrocytes and the consequent glutamate release from these cells...
  31. ncbi request reprint Changes in the Morphology and Proliferation of Astrocytes Induced by Two Modalities of Chemically Functionalized Single-Walled Carbon Nanotubes are Differentially Mediated by Glial Fibrillary Acidic Protein
    Manoj K Gottipati
    Department of Neurobiology, University of Alabama, Birmingham, Alabama 35294, United States
    Nano Lett 14:3720-7. 2014
    ..We find that selected astrocytic changes induced by CNTs are mediated by GFAP, i.e., perimeter, shape, and cell death for solutes, and proliferation for films. ..
  32. doi request reprint Heterogeneity of myotubes generated by the MyoD and E12 basic helix-loop-helix transcription factors in otherwise non-differentiation growth conditions
    Vladimir Grubisic
    Department of Neurobiology, University of Alabama, Birmingham, AL 35294, USA
    Biomaterials 35:2188-98. 2014
    ....
  33. doi request reprint Voltage-gated calcium channel types in cultured C. elegans CEPsh glial cells
    Randy F Stout
    Department of Neurobiology, Center for Glial Biology in Medicine, Atomic Force Microscopy and Nanotechnology Laboratories, Civitan International Research Center, Evelyn F McKnight Brain Institute, University of Alabama, Birmingham, AL 35294, USA
    Cell Calcium 50:98-108. 2011
    ..We suggest that VGCC-mediated Ca(2+) dynamics in the CEPsh glial cells are complex and display heterogeneity. These findings will aid understanding of how CEPsh glial cells contribute to the operation of the C. elegans nervous system...
  34. pmc Carbon nanotubes in neuroscience
    Erik B Malarkey
    Department of Neurobiology Center for Gilial Biology in Medicine, Atomic Force Microscopy and Nanotechnology Laboratories, Civitan International Research Center, Evelyn F McKnight Brain Institute, University of Alabama, Birmingham, AL 35294, USA
    Acta Neurochir Suppl 106:337-41. 2010
    ..The emerging picture is that carbon nanotubes do not have obvious adverse effects on mammalian health. Thus in the near future they could be used in brain-machine interfaces...
  35. pmc Single molecule probing of SNARE proteins by atomic force microscopy
    Wei Liu
    Department of Neurobiology, Center for Glial Biology in Medicine, Atomic Force Microscopy and Nanotechnology Laboratories, Civitan International Research Center, Evelyn F McKnight Brain Institute, University of Alabama, Birmingham, Alabama 35294, USA
    Ann N Y Acad Sci 1152:113-20. 2009
    ..These measurements, which are complementary to results and conclusions drawn from other techniques, improve our understanding of the role of the SNARE complex in exocytosis...
  36. pmc SNAREs: could they be the answer to an energy landscape riddle in exocytosis?
    Wei Liu
    Department of Neurobiology, Atomic Force Microscopy and Nanotechnology Laboratories, Center for Glial Biology in Medicine, Civitan International Research Center, and Evelyn F McKnight Brain Institute, University of Alabama, Birmingham, USA
    ScientificWorldJournal 10:1258-68. 2010
    ....
  37. pmc Interaction of ASIC1 and ENaC subunits in human glioma cells and rat astrocytes
    Niren Kapoor
    Dept of Physiology and Biophysics, University of Alabama at Birmingham, 1918 University Blvd, Birmingham, AL 35294, USA
    Am J Physiol Cell Physiol 300:C1246-59. 2011
    ..These data suggest that different ENaC/Deg subunits interact and could combine to form a hybrid channel that likely underlies the amiloride-sensitive current seen in human glioma cells...
  38. pmc Epigallocatechin gallate (EGCG) stimulates autophagy in vascular endothelial cells: a potential role for reducing lipid accumulation
    Hae Suk Kim
    Department of Medicine, Division of Endocrinology, Diabetes, and Metabolism, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
    J Biol Chem 288:22693-705. 2013
    ..Collectively, these findings suggest that EGCG regulates ectopic lipid accumulation through a facilitated autophagic flux and further imply that EGCG may be a potential therapeutic reagent to prevent cardiovascular complications. ..
  39. doi request reprint Mitochondrial exchanger NCLX plays a major role in the intracellular Ca2+ signaling, gliotransmission, and proliferation of astrocytes
    Julia Parnis
    Cellular Neurosciences, Max Delbruck Centre for Molecular Medicine, Berlin 13092, Germany
    J Neurosci 33:7206-19. 2013
    ....
  40. pmc Single-walled carbon nanotubes chemically functionalized with polyethylene glycol promote tissue repair in a rat model of spinal cord injury
    Jose A Roman
    Department of Physical Medicine and Rehabilitation, University of Alabama Birmingham, Birmingham, Alabama 35249, USA
    J Neurotrauma 28:2349-62. 2011
    ..These data suggest that SWNT-PEG may be an effective material to promote axonal repair and regeneration after SCI...
  41. pmc Temporal characteristics of vesicular fusion in astrocytes: examination of synaptobrevin 2-laden vesicles at single vesicle resolution
    Erik B Malarkey
    Departments of Neurobiology and Cell Biology, Center for Glial Biology inMedicine, Atomic Force Microscopy and Nanotechnology Laboratories, Civitan International Research Center, Evelyn F McKnight Brain Institute, University of Alabama, Birmingham, AL, USA
    J Physiol 589:4271-300. 2011
    ..Our detailed study of temporal characteristics of astrocytic exocytosis will not only aid the general understanding of this process, but also the interpretation of the events at the tripartite synapse, both in health and disease...
  42. ncbi request reprint Nanofabricated carbon-based detector
    Vladimir Parpura
    Department of Cell Biology and Neuroscience and Center for Nanoscale Science and Engineering, University of California, Riverside, California 92521, USA
    Anal Chem 77:681-6. 2005
    ..Thus, this detector will aid future studies of single secretory granules and vesicles and their insoluble matrixes...
  43. ncbi request reprint Applications of carbon nanotubes in neurobiology
    Erik B Malarkey
    Department of Cell Biology and Neuroscience, Centers for Glial Neuronal Interactions and Nanoscale Science and Engineering, University of California, Riverside, CA 92521, USA
    Neurodegener Dis 4:292-9. 2007
    ..There are numerous properties of carbon nanotubes that make them attractive for applications in neurobiology: small size, flexibility, strength, inertness, electrical conductivity and ease of modification with biological compounds...
  44. ncbi request reprint Separation of individual neurons using dielectrophoretic alternative current fields
    Shalini Prasad
    Department of Electrical Engineering, University of California Riverside, A 220 Bourns Hall, Riverside, CA 92521, USA
    J Neurosci Methods 135:79-88. 2004
    ..The frequency spectrum of the electrical activity was generated using fast Fourier transformation analysis (FFT) to determine the characteristic burst rates of individual neurons...
  45. ncbi request reprint Chemically functionalized water soluble single-walled carbon nanotubes modulate neurite outgrowth
    Yingchun Ni
    Department of Cell Biology and Neuroscience, Center for Nanoscale Science and Engineering, University of California, Riverside, CA 92521, USA
    J Nanosci Nanotechnol 5:1707-12. 2005
    ..When added to the culturing medium, these functionalized water soluble SWNTs were able to increase the length of various neuronal processes...

Research Grants7

  1. Calcium-dependent glutamate release from astrocytes
    Vladimir Parpura; Fiscal Year: 2007
    ..Since astrocytes modulate synaptic transmission by releasing glutamate, this new insight into glial action has potential to change the way we think about central nervous system functions and dysfunctions ..
  2. Calcium-dependent glutamate release from astrocytes
    Vladimir Parpura; Fiscal Year: 2004
    ..Since astrocytes modulate synaptic transmission by releasing glutamate, this new insight into glial action has potential to change the way we think about central nervous system functions and dysfunctions ..
  3. Calcium-dependent glutamate release from astrocytes
    Vladimir Parpura; Fiscal Year: 2005
    ..Since astrocytes modulate synaptic transmission by releasing glutamate, this new insight into glial action has potential to change the way we think about central nervous system functions and dysfunctions ..
  4. Calcium-dependent glutamate release from astrocytes
    Vladimir Parpura; Fiscal Year: 2006
    ..Since astrocytes modulate synaptic transmission by releasing glutamate, this new insight into glial action has potential to change the way we think about central nervous system functions and dysfunctions ..
  5. Glial Biology Gordon Research Conference
    Vladimir Parpura; Fiscal Year: 2007
    ..This Glial Biology Conference provides an international forum for emerging, innovative research related to glia functions and cell-cell interactions in health and disease. ..
  6. Calcium-dependent glutamate release from astrocytes
    Vladimir Parpura; Fiscal Year: 2007
    ..Since astrocytes modulate synaptic transmission by releasing glutamate, this new insight into glial action has potential to change the way we think about central nervous system functions and dysfunctions ..