Thomas J Park

Summary

Affiliation: University of Illinois at Chicago
Country: USA

Publications

  1. pmc Selective inflammatory pain insensitivity in the African naked mole-rat (Heterocephalus glaber)
    Thomas J Park
    Laboratory of Integrative Neuroscience, Department of Biological Sciences, University of Illinois at Chicago, Chicago, Illinois, United States of America
    PLoS Biol 6:e13. 2008
  2. pmc Blunted neuronal calcium response to hypoxia in naked mole-rat hippocampus
    Bethany L Peterson
    Department of Biological Sciences, University of Illinois at Chicago, Chicago, Illinois, United States of America
    PLoS ONE 7:e31568. 2012
  3. pmc Blunted behavioral and c Fos responses to acidic fumes in the African naked mole-rat
    Pamela Colleen LaVinka
    Department of Biological Sciences and the Laboratory of Integrative Neuroscience, University of Illinois at Chicago, Chicago, Illinois, USA
    PLoS ONE 7:e45060. 2012
  4. pmc Functional neurokinin and NMDA receptor activity in an animal naturally lacking substance P: the naked mole-rat
    Antje Brand
    Laboratory of Integrative Neuroscience, Department of Biological Sciences, University of Illinois at Chicago, Chicago, Illinois, United States of America
    PLoS ONE 5:e15162. 2010
  5. pmc Absence of histamine-induced itch in the African naked mole-rat and "rescue" by Substance P
    Ewan St John Smith
    Department of Neuroscience, Max Delbruck Center for Molecular Medicine, Robert Rossle Strasse 10, 13125 Berlin Buch, Germany
    Mol Pain 6:29. 2010
  6. ncbi request reprint Interaural level difference processing in the lateral superior olive and the inferior colliculus
    Thomas J Park
    University of Illinois at Chicago, Laboratory of Integrative Neuroscience, Department of Biological Sciences, 840 W Taylor St, Chicago, IL 60607, USA
    J Neurophysiol 92:289-301. 2004
  7. ncbi request reprint Somatosensory organization and behavior in naked mole-rats: II. Peripheral structures, innervation, and selective lack of neuropeptides associated with thermoregulation and pain
    Thomas J Park
    Department of Biological Sciences, University of Illinois at Chicago, Chicago, Illinois 60607, USA
    J Comp Neurol 465:104-20. 2003
  8. pmc Dynamic changes in level influence spatial coding in the lateral superior olive
    Thomas J Park
    Laboratory of Integrative Neuroscience, Department of Biological Sciences, University of Illinois at Chicago, Chicago, IL 60607, USA
    Hear Res 238:58-67. 2008
  9. doi request reprint Extreme tolerance to ammonia fumes in African naked mole-rats: animals that naturally lack neuropeptides from trigeminal chemosensory nerve fibers
    Pamela Colleen LaVinka
    University of Illinois at Chicago, Biological Sciences, 840 W Taylor St, Chicago, IL 60607, USA
    J Comp Physiol A Neuroethol Sens Neural Behav Physiol 195:419-27. 2009
  10. doi request reprint Extreme hypoxia tolerance of naked mole-rat brain
    John Larson
    Department of Psychiatry, Psychiatric Institute, University of Illinois, Chicago, Illinois 60612, USA
    Neuroreport 20:1634-7. 2009

Detail Information

Publications20

  1. pmc Selective inflammatory pain insensitivity in the African naked mole-rat (Heterocephalus glaber)
    Thomas J Park
    Laboratory of Integrative Neuroscience, Department of Biological Sciences, University of Illinois at Chicago, Chicago, Illinois, United States of America
    PLoS Biol 6:e13. 2008
    ..The pain biology of the naked mole-rat is unique among mammals, thus the study of pain mechanisms in this unusual species can provide major insights into what constitutes "normal" mammalian nociception...
  2. pmc Blunted neuronal calcium response to hypoxia in naked mole-rat hippocampus
    Bethany L Peterson
    Department of Biological Sciences, University of Illinois at Chicago, Chicago, Illinois, United States of America
    PLoS ONE 7:e31568. 2012
    ..The results are discussed in terms of a general hypothesis that a very prolonged or arrested developmental process may allow adult naked mole-rat brain to retain the hypoxia tolerance normally only seen in neonatal mammals...
  3. pmc Blunted behavioral and c Fos responses to acidic fumes in the African naked mole-rat
    Pamela Colleen LaVinka
    Department of Biological Sciences and the Laboratory of Integrative Neuroscience, University of Illinois at Chicago, Chicago, Illinois, USA
    PLoS ONE 7:e45060. 2012
    ....
  4. pmc Functional neurokinin and NMDA receptor activity in an animal naturally lacking substance P: the naked mole-rat
    Antje Brand
    Laboratory of Integrative Neuroscience, Department of Biological Sciences, University of Illinois at Chicago, Chicago, Illinois, United States of America
    PLoS ONE 5:e15162. 2010
    ....
  5. pmc Absence of histamine-induced itch in the African naked mole-rat and "rescue" by Substance P
    Ewan St John Smith
    Department of Neuroscience, Max Delbruck Center for Molecular Medicine, Robert Rossle Strasse 10, 13125 Berlin Buch, Germany
    Mol Pain 6:29. 2010
    ..These results illustrate that it is altered dorsal horn connectivity of nociceptors that underlies the lack of itch and pain-related behavior in the naked mole-rat...
  6. ncbi request reprint Interaural level difference processing in the lateral superior olive and the inferior colliculus
    Thomas J Park
    University of Illinois at Chicago, Laboratory of Integrative Neuroscience, Department of Biological Sciences, 840 W Taylor St, Chicago, IL 60607, USA
    J Neurophysiol 92:289-301. 2004
    ..Furthermore, a population analysis based on proportion of active cells indicated that stability in the ICC was greatly enhanced when overall population activity was considered...
  7. ncbi request reprint Somatosensory organization and behavior in naked mole-rats: II. Peripheral structures, innervation, and selective lack of neuropeptides associated with thermoregulation and pain
    Thomas J Park
    Department of Biological Sciences, University of Illinois at Chicago, Chicago, Illinois 60607, USA
    J Comp Neurol 465:104-20. 2003
    ..The features of this mammalian model system provide unique opportunities to discriminate mechanisms related to tactile spatial orientation, vascular regulation, and nociception...
  8. pmc Dynamic changes in level influence spatial coding in the lateral superior olive
    Thomas J Park
    Laboratory of Integrative Neuroscience, Department of Biological Sciences, University of Illinois at Chicago, Chicago, IL 60607, USA
    Hear Res 238:58-67. 2008
    ..Hence, sensitivity to ensuing stimuli is already established at the first synaptic station of binaural processing...
  9. doi request reprint Extreme tolerance to ammonia fumes in African naked mole-rats: animals that naturally lack neuropeptides from trigeminal chemosensory nerve fibers
    Pamela Colleen LaVinka
    University of Illinois at Chicago, Biological Sciences, 840 W Taylor St, Chicago, IL 60607, USA
    J Comp Physiol A Neuroethol Sens Neural Behav Physiol 195:419-27. 2009
    ....
  10. doi request reprint Extreme hypoxia tolerance of naked mole-rat brain
    John Larson
    Department of Psychiatry, Psychiatric Institute, University of Illinois, Chicago, Illinois 60612, USA
    Neuroreport 20:1634-7. 2009
    ..We suggest that brain tolerance to hypoxia may result from slowed or arrested brain development in these extremely long-lived animals...
  11. doi request reprint Adult naked mole-rat brain retains the NMDA receptor subunit GluN2D associated with hypoxia tolerance in neonatal mammals
    Bethany L Peterson
    Department of Biological Sciences, University of Illinois at Chicago, 840 West Taylor St, Chicago, IL 60607, USA
    Neurosci Lett 506:342-5. 2012
    ..Hence, adult naked mole-rat brain only retains the neonatal NMDA receptor subunit that is associated with hypoxia tolerance...
  12. ncbi request reprint Somatosensory organization and behavior in naked mole-rats I: vibrissa-like body hairs comprise a sensory array that mediates orientation to tactile stimuli
    Samuel D Crish
    Laboratory of Integrative Neuroscience and Department of Biological Sciences, University of Illinois at Chicago, Chicago, IL 60607, USA
    Brain Behav Evol 62:141-51. 2003
    ....
  13. ncbi request reprint Features of visual function in the naked mole-rat Heterocephalus glaber
    John R Hetling
    Department of Bioengineering, University of Illinois at Chicago, 851 South Morgan Street, Room 232, M C 063, Chicago, IL 60607 7052, USA
    J Comp Physiol A Neuroethol Sens Neural Behav Physiol 191:317-30. 2005
    ..Results are consistent with amorphous light detection, possibly useful for circadian entrainment or escape behavior in the event of tunnel breeches...
  14. pmc Extreme susceptibility of African naked mole rats (Heterocephalus glaber) to experimental infection with herpes simplex virus type 1
    James Artwohl
    Biological Resources Laboratory, University of Illinois at Chicago, Chicago, Illinois, USA
    Comp Med 59:83-90. 2009
    ..We conclude that the lethality of HSV1 for naked mole rats is likely the result of overwhelming infection, possibly in part due to this species' natural lack of proinflammatory neuropeptides at the initial site of infection...
  15. doi request reprint No oxygen? No problem! Intrinsic brain tolerance to hypoxia in vertebrates
    John Larson
    Psychiatric Institute, Department of Psychiatry and Laboratory of Integrative Neuroscience, Department of Biological Sciences, University of Illinois, Chicago, IL 60612, USA
    J Exp Biol 217:1024-39. 2014
    ....
  16. doi request reprint Retrograde GABA signaling adjusts sound localization by balancing excitation and inhibition in the brainstem
    Anna K Magnusson
    Department Biologie II, Division of Neurobiology, LMU Munich, Grosshadernerstrasse 2, 82152 Martinsried, Germany
    Neuron 59:125-37. 2008
    ....
  17. ncbi request reprint A plethora of painful molecules
    Gary R Lewin
    Growth Factors and Regeneration Group, Max Delbruck Center for Molecular Medicine, Robert Rossle Str 10, Berlin Buch D 13092 Germany
    Curr Opin Neurobiol 14:443-9. 2004
    ..The rich variety of key molecular players that have emerged in physiological and pathophysiological pain states reflects the sophistication and uniqueness of this vitally important sense...
  18. ncbi request reprint Roles of inhibition for transforming binaural properties in the brainstem auditory system
    George D Pollak
    Section of Neurobiology, The University of Texas at Austin, Austin, TX 78731, USA
    Hear Res 168:60-78. 2002
    ....
  19. ncbi request reprint Growth-deficient vomeronasal organs in the naked mole-rat (Heterocephalus glaber)
    Timothy D Smith
    School of Physical Therapy, Slippery Rock University, Slippery Rock, PA 16057, USA
    Brain Res 1132:78-83. 2007
    ....
  20. ncbi request reprint Localization of the cytochrome p450 side-chain cleavage enzyme in the inactive testis of the naked mole-rat
    Hideki Endo
    Department of Zoology, National Science Museum, Tokyo, 3 23 1 Hyakunin cho, Shinjuku ku, Tokyo 169 0073, Japan
    Zoolog Sci 19:673-8. 2002
    ..The TUNEL methods demonstrated that cell death occurred in some spermatocytes in non-breeding males...