Research Topics
Species | Jong ParkSummaryAffiliation: University of South Florida Country: USA Publications
Research Grants
| Collaborators
|
Detail Information
Publications
Polymorphisms in the promoter region of neutrophil elastase gene and lung cancer riskJong Y Park
Division of Cancer Prevention and Control, Department of Interdisciplinary, H Lee Moffitt Cancer Center and Research Institute, 12902 Magnolia Drive, MRC3047A, Tampa, FL 33612, USA
Lung Cancer 48:315-21. 2005..These results confirm that the NE promoter region polymorphisms may influence in risk for lung cancer...- Deletion polymorphism of UDP-glucuronosyltransferase 2B17 and risk of prostate cancer in African American and Caucasian menJong Park
Division of Cancer Prevention and Control, H Lee Moffitt Cancer Center, Tampa, FL 33612, USA
Cancer Epidemiol Biomarkers Prev 15:1473-8. 2006..The purpose of this study was to determine if the deletion polymorphism is associated with susceptibility to prostate cancer... - Polymorphisms for microsomal epoxide hydrolase and genetic susceptibility to COPDJong Y Park
Division of Cancer Prevention and Controls, Molecular Screening Section, H Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA
Int J Mol Med 15:443-8. 2005..As expected, a significant correlation between smoking dose and severity of COPD was observed (p<0.001). These results suggest that EH codon 113 polymorphism may modify risk for COPD... - CpG island hypermethylation profiling of lung cancer using restriction landmark genomic scanning (RLGS) analysisJong Park
Division of Cancer Prevention and Controls, H Lee Moffitt Cancer Center and Research Institute, 12902 Magnolia Drive, Tampa, FL 33612, USA
Cancer Biomark 1:193-200. 2005..Among 162 sites of differential DNA methylation, detected from at least one tumor/normal pair, 21 hypermethylated genes were identified that were not reported previously as hypermethylated in lung tumor tissue... - Asp85tyr polymorphism in the udp-glucuronosyltransferase (UGT) 2B15 gene and the risk of prostate cancerJong Park
Department of Interdisciplinary Oncology, University of South Florida, Tampa, Florida 33612, USA
J Urol 171:2484-8. 2004..We determined whether this polymorphism can be used to predict individual susceptibility to prostate cancer... - The human 8-oxoguanine DNA N-glycosylase 1 (hOGG1) DNA repair enzyme and its association with lung cancer riskJong Park
Divisions of Cancer Control and Molecular Oncology, H Lee Moffitt Cancer Center, University of South Florida, Tampa, FL 33612, USA
Pharmacogenetics 14:103-9. 2004..The goal of the present study is to determine whether the codon 326 polymorphism was significantly associated with alterations in individual risk for lung cancer... - Epoxide hydrolase genotype and orolaryngeal cancer risk: interaction with GSTM1 genotypeJong Y Park
Division of Cancer Controls, H Lee Moffitt Cancer Center and Research Institute, Department of Interdisciplinary Oncology, 12902 Magnolia Drive, Tampa, FL 33612, USA
Oral Oncol 39:483-90. 2003..5, 95% CI=1.3-9.3) but not GSTM [+] (OR=0.9, 95%CI=0.4-2.1) genotype. These results suggest that EH polymorphisms play an important role in risk for orolaryngeal cancer in Caucasians... - Genetic analysis of microsomal epoxide hydrolase gene and its association with lung cancer riskJ Y Park
Division of Cancer Prevention and Control, 12902 Magnolia Drive, H Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA
Eur J Cancer Prev 14:223-30. 2005..This association was more pronounced among patients with lung adenocarcinoma (OR 4.7, 95% CI 1.7-13.1). These results suggest that the EH polymorphism plays an important role in lung cancer risk and is linked to tobacco smoke exposure... - Association between polymorphism of human oxoguanine glycosylase 1 and risk of prostate cancerLan Chen
Genitourinary Division, H Lee Moffitt Cancer Center, University of South Florida, Tampa 33612, USA
J Urol 170:2471-4. 2003..To determine whether hOGG1 has a role in the risk of prostate cancer we screened normal prostate tissue specimens for hOGG1 expression and assessed the role of hOGG1 Ser326Cys polymorphism in the risk of prostate cancer... - The human OGG1 DNA repair enzyme and its association with orolaryngeal cancer riskAbul Elahi
Divisions of Cancer Control and Molecular Oncology, H Lee Moffitt Cancer Center, University of South Florida, Tampa, FL, USA
Carcinogenesis 23:1229-34. 2002.... - Tobacco carcinogen-detoxifying enzyme UGT1A7 and its association with orolaryngeal cancer riskZ Zheng
Division of Cancer Control, H Lee Moffitt Cancer Center and Research Institute, Interdisciplinary Oncology Program and Department of Biochemistry, University of South Florida, Tampa 33612, USA
J Natl Cancer Inst 93:1411-8. 2001..We determined whether UGT1A7 expression is observed in normal orolaryngeal tissue and whether UGT1A7 allelic variations are associated with the risk for orolaryngeal cancer... - Metabolizing enzyme genotype and risk for upper aerodigestive tract cancerP Lazarus
H Lee Moffitt Cancer Center, Divisions of Cancer Control and Molecular Oncology, University of South Florida, MRC 2E, 12902 Magnolia Drive, Tampa, FL 33612, USA
Oral Oncol 36:421-31. 2000.... - Neurocognitive variation in smoking behavior and withdrawal: genetic and affective moderatorsD E Evans
Tobacco Research and Intervention Program, Moffitt Cancer Center, Tampa, FL 33617, USA
Genes Brain Behav 8:86-96. 2009..This research contributes to a better understanding of the role of individual differences and attentional processing in smoking behavior... - Association between polymorphisms in the DNA repair genes XRCC1 and APE1, and the risk of prostate cancer in white and black AmericansLan Chen
Division of Cancer Prevention and Control, H Lee Moffitt Cancer Center, Tampa, Florida, USA
J Urol 175:108-12; discussion 112. 2006..XRCC1 and APE1 are enzymes involved in the repair of DNA strand breaks and base damage that arise from various endogenous and exogenous oxidants. We determined whether polymorphisms in XRCC1 and APE1 increase the risk of prostate cancer... - Polymorphisms in genes coding for enzymes metabolizing smoking-derived substances and the risk of periodontitisJeong Sook Kim
Department of Periodontology, Yonsei University College of Dentistry, 134 Shinchon dong, Seodaemoon ku, Seoul 120 752, South Korea
J Clin Periodontol 31:959-64. 2004..The object of this study is to investigate roles of genetic polymorphisms of these metabolizing enzymes in the risk for periodontitis... - Association between polymorphisms in HSD3B1 and UGT2B17 and prostate cancer riskJong Y Park
Division of Cancer Prevention and Control, H Lee Moffitt Cancer Center and Research Institute, Tampa, Florida 33612, USA
Urology 70:374-9. 2007..The purpose of this study was to determine whether polymorphisms in HSD3B1 and UGT2B17 increase the risk of prostate cancer... - Candidate tumor suppressor gene SLC5A8 is frequently down-regulated by promoter hypermethylation in prostate tumorJong Y Park
Division of Cancer Prevention and Control, H Lee Moffitt Cancer Center and Research Institute, 12902 Magnolia Drive, Tampa, FL 33612, USA
Cancer Detect Prev 31:359-65. 2007..The aim of this study was to investigate the significance of DNA methylation in SLC5A8 expression in prostate tumors... - Silencing of the candidate tumor suppressor gene solute carrier family 5 member 8 (SLC5A8) in human pancreatic cancerJong Y Park
Division of Cancer Prevention and Control, H Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA
Pancreas 36:e32-9. 2008.... - Outcomes following resection of pancreatic adenocarcinoma: 20-year experience at a single institutionJames F Helm
Gastrointestinal Tumor Program, H Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA
Cancer Control 15:288-94. 2008....
Research Grants
- Elucidation of epoxide hydrolase polymorphismsJong Park; Fiscal Year: 2002....
- Epigenetic Markers for Lung Cancer DetectionJong Park; Fiscal Year: 2006..The proposed study will generate data that will be the groundwork for larger studies to validate the use of the identified methylation sites to develop markers for early lung cancer diagnosis. ..