Jin Young Park

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi request reprint Targeting the PI3K-Akt pathway in kidney cancer
    Jin Young Park
    Division of Nephrology, Department of Internal Medicine, Immunology Graduate Group, University of California, Davis, CA 95616, USA
    Expert Rev Anticancer Ther 7:863-70. 2007
  2. pmc p21 is decreased in polycystic kidney disease and leads to increased epithelial cell cycle progression: roscovitine augments p21 levels
    Jin Young Park
    Immunology Graduate Group, University of California, Davis, CA, USA
    BMC Nephrol 8:12. 2007
  3. pmc Attenuation of PTEN increases p21 stability and cytosolic localization in kidney cancer cells: a potential mechanism of apoptosis resistance
    Pei yin Lin
    Division of Nephrology, Department of Internal Medicine, University of California, Davis, CA, USA
    Mol Cancer 6:16. 2007
  4. pmc Disparate effects of roscovitine on renal tubular epithelial cell apoptosis and senescence: implications for autosomal dominant polycystic kidney disease
    Jin Young Park
    Division of Nephrology, Department of Internal Medicine, University of California, Davis, CA 95616, USA
    Am J Nephrol 29:509-15. 2009
  5. pmc Antisense attenuation of p21 sensitizes kidney cancer to apoptosis in response to conventional DNA damaging chemotherapy associated with enhancement of phospho-p53
    See Hyoung Park
    Division of Nephrology, Department of Internal Medicine and Cancer Center, University of California, Davis, California 95616, USA
    J Urol 180:352-60. 2008

Collaborators

Detail Information

Publications5

  1. ncbi request reprint Targeting the PI3K-Akt pathway in kidney cancer
    Jin Young Park
    Division of Nephrology, Department of Internal Medicine, Immunology Graduate Group, University of California, Davis, CA 95616, USA
    Expert Rev Anticancer Ther 7:863-70. 2007
    ..In this review, we discuss PI3K-Akt inhibitors as well as inhibitors of pathways and targets both immediately up- and downstream of this cascade, many of which show promise in the clinic...
  2. pmc p21 is decreased in polycystic kidney disease and leads to increased epithelial cell cycle progression: roscovitine augments p21 levels
    Jin Young Park
    Immunology Graduate Group, University of California, Davis, CA, USA
    BMC Nephrol 8:12. 2007
    ....
  3. pmc Attenuation of PTEN increases p21 stability and cytosolic localization in kidney cancer cells: a potential mechanism of apoptosis resistance
    Pei yin Lin
    Division of Nephrology, Department of Internal Medicine, University of California, Davis, CA, USA
    Mol Cancer 6:16. 2007
    ..Renal cell carcinoma (RCC) is associated with frequent treatment failures (approximately 90% in metastatic cases), and these tumors frequently contain PTEN abnormalities...
  4. pmc Disparate effects of roscovitine on renal tubular epithelial cell apoptosis and senescence: implications for autosomal dominant polycystic kidney disease
    Jin Young Park
    Division of Nephrology, Department of Internal Medicine, University of California, Davis, CA 95616, USA
    Am J Nephrol 29:509-15. 2009
    ..The cyclin kinase inhibitor roscovitine has shown efficacy in treatment of murine PKD. We asked how a single agent can be efficacious in both PKD and cancer...
  5. pmc Antisense attenuation of p21 sensitizes kidney cancer to apoptosis in response to conventional DNA damaging chemotherapy associated with enhancement of phospho-p53
    See Hyoung Park
    Division of Nephrology, Department of Internal Medicine and Cancer Center, University of California, Davis, California 95616, USA
    J Urol 180:352-60. 2008
    ..We capitalized on this function of p21 and used an antisense approach to sensitize p53-wt renal cell carcinoma cells to chemotherapy induced apoptosis by attenuating p21 protein levels...