In Hyun Park

Summary

Affiliation: University of Illinois
Country: USA

Publications

  1. ncbi request reprint Skeletal myocyte hypertrophy requires mTOR kinase activity and S6K1
    In Hyun Park
    Department of Cell and Structural Biology, University of Illinois at Urbana Champaign, Urbana, IL 61801, USA
    Exp Cell Res 309:211-9. 2005
  2. ncbi request reprint Regulation of ribosomal S6 kinase 2 by mammalian target of rapamycin
    In Hyun Park
    Department of Cell and Structural Biology, University of Illinois at Urbana Champaign, Urbana, Illinois 61801, USA
    J Biol Chem 277:31423-9. 2002
  3. ncbi request reprint PLD1 regulates mTOR signaling and mediates Cdc42 activation of S6K1
    Yimin Fang
    Department of Cell and Structural Biology, University of Illinois at Urbana Champaign, 601 S Goodwin Avenue B107, Urbana, IL 61801, USA
    Curr Biol 13:2037-44. 2003
  4. pmc IGF-II transcription in skeletal myogenesis is controlled by mTOR and nutrients
    Ebru Erbay
    Department of Cell and Structural Biology, University of Illinois at Urbana Champaign, 601 S Goodwin Ave, B107, Urbana, IL 61801, USA
    J Cell Biol 163:931-6. 2003
  5. ncbi request reprint Mammalian target of rapamycin (mTOR) signaling is required for a late-stage fusion process during skeletal myotube maturation
    In Hyun Park
    Department of Cell and Developmental Biology, University of Illinois at Urbana Champaign, Urbana, Illinois 61801, USA
    J Biol Chem 280:32009-17. 2005
  6. ncbi request reprint A nuclear transport signal in mammalian target of rapamycin is critical for its cytoplasmic signaling to S6 kinase 1
    Rebecca A Bachmann
    Department of Cell and Developmental Biology, University of Illinois at Urbana Champaign, 601 S Goodwin Avenue, Urbana, IL 61801, USA
    J Biol Chem 281:7357-63. 2006

Collaborators

  • Jie Chen
  • Guangwei Du
  • Rebecca A Bachmann
  • Ai Luen Wu
  • Ebru Erbay
  • Yimin Fang
  • Jeong Ho Kim
  • Paul D Nuzzi
  • Michael A Frohman
  • Christopher J Schoenherr
  • H Alex Brown
  • Ping Huang
  • Stephanie J Walker

Detail Information

Publications6

  1. ncbi request reprint Skeletal myocyte hypertrophy requires mTOR kinase activity and S6K1
    In Hyun Park
    Department of Cell and Structural Biology, University of Illinois at Urbana Champaign, Urbana, IL 61801, USA
    Exp Cell Res 309:211-9. 2005
    ....
  2. ncbi request reprint Regulation of ribosomal S6 kinase 2 by mammalian target of rapamycin
    In Hyun Park
    Department of Cell and Structural Biology, University of Illinois at Urbana Champaign, Urbana, Illinois 61801, USA
    J Biol Chem 277:31423-9. 2002
    ..Taken together, our observations suggest a novel regulatory mechanism in which an optimal cytoplasmic-nuclear distribution or shuttling rate for mTOR is required for maximal activation of the nuclear S6K2...
  3. ncbi request reprint PLD1 regulates mTOR signaling and mediates Cdc42 activation of S6K1
    Yimin Fang
    Department of Cell and Structural Biology, University of Illinois at Urbana Champaign, 601 S Goodwin Avenue B107, Urbana, IL 61801, USA
    Curr Biol 13:2037-44. 2003
    ..In this study, we set out to test the hypotheses that phospholipase D 1 (PLD1) is an upstream regulator of mTOR and that the previously reported S6K1 activation by Cdc42 is mediated by PLD1...
  4. pmc IGF-II transcription in skeletal myogenesis is controlled by mTOR and nutrients
    Ebru Erbay
    Department of Cell and Structural Biology, University of Illinois at Urbana Champaign, 601 S Goodwin Ave, B107, Urbana, IL 61801, USA
    J Cell Biol 163:931-6. 2003
    ..Our findings represent the first identification of a signaling pathway that regulates IGF-II expression in myogenesis and implicate the mTOR-IGF axis as a molecular link between nutritional levels and skeletal muscle development...
  5. ncbi request reprint Mammalian target of rapamycin (mTOR) signaling is required for a late-stage fusion process during skeletal myotube maturation
    In Hyun Park
    Department of Cell and Developmental Biology, University of Illinois at Urbana Champaign, Urbana, Illinois 61801, USA
    J Biol Chem 280:32009-17. 2005
    ....
  6. ncbi request reprint A nuclear transport signal in mammalian target of rapamycin is critical for its cytoplasmic signaling to S6 kinase 1
    Rebecca A Bachmann
    Department of Cell and Developmental Biology, University of Illinois at Urbana Champaign, 601 S Goodwin Avenue, Urbana, IL 61801, USA
    J Biol Chem 281:7357-63. 2006
    ..Taken together, our observations suggest the existence of a nuclear shuttling signal in mTOR and provide definitive evidence for the requirement of mTOR nuclear import in its cytoplasmic signaling to S6K1...