Genomes and Genes
Affiliation: University of Chicago
- The radial glia antibody RC2 recognizes a protein encoded by NestinDonghyun Park
Howard Hughes Medical Institute, Department of Human Genetics, University of Chicago, 929E, 57th, W503B, Chicago, IL 60637, USA
Biochem Biophys Res Commun 382:588-92. 2009..Furthermore, our data suggest that the RC2 antibody recognizes the C-terminal domain of nestin with unidentified posttranslational modification(s)...
- Nestin is required for the proper self-renewal of neural stem cellsDonghyun Park
Department of Human Genetics, University of Chicago, Howard Hughes Medical Institute, Chicago, Illinois, USA
Stem Cells 28:2162-71. 2010..These data demonstrate that nestin is important for the proper survival and self-renewal of NSCs, and that this function is surprisingly uncoupled from nestin's structural involvement in the cytoskeleton...
- Systematic mapping of occluded genes by cell fusion reveals prevalence and stability of cis-mediated silencing in somatic cellsTimothy J Looney
Department of Human Genetics, University of Chicago, Howard Hughes Medical Institute, Chicago, Illinois 60637, USA
Genome Res 24:267-80. 2014..The comprehensive reference maps reported here provide the foundation for future studies aimed at understanding the role of occlusion in development and disease. ..
- Analysis of human disease genes in the context of gene essentialityDonghyun Park
Howard Huges Medical Institute, Department of Human Genetics, University of Chicago, Chicago, IL, USA
Genomics 92:414-8. 2008..Furthermore, missense disease mutations in no phenotype genes were found to be more radical amino acid substitutions than those in phenotype genes...