Catherine C Park

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc Rapid and automated multidimensional fluorescence microscopy profiling of 3D human breast cultures
    Catherine C Park
    Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA
    Integr Biol (Camb) 5:681-91. 2013
  2. pmc β1 integrin mediates an alternative survival pathway in breast cancer cells resistant to lapatinib
    Catherine Huang
    Lester and Sue Smith Breast Center, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77054, USA
    Breast Cancer Res 13:R84. 2011
  3. doi request reprint American Society for Therapeutic Radiology and Oncology (ASTRO) Emerging Technology Committee report on electronic brachytherapy
    Catherine C Park
    Department of Radiation Oncology, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, 1600 Divisadero St, H1031, San Francisco, CA 94143 1708, USA
    Int J Radiat Oncol Biol Phys 76:963-72. 2010
  4. pmc NF-κB regulates radioresistance mediated by β1-integrin in three-dimensional culture of breast cancer cells
    Kazi Mokim Ahmed
    Department of Cancer and DNA Damage Responses, Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley
    Cancer Res 73:3737-48. 2013
  5. pmc HER2 signaling pathway activation and response of breast cancer cells to HER2-targeting agents is dependent strongly on the 3D microenvironment
    Britta Weigelt
    Life Sciences Division, Lawrence Berkeley National Laboratory, University of California Berkeley, Mailstop 977R225A, 1 Cyclotron Road, Berkeley, CA 94720, USA
    Breast Cancer Res Treat 122:35-43. 2010
  6. doi request reprint beta1 integrin targeting to enhance radiation therapy
    Jin Min Nam
    Life Sciences Division, Ernest Orlando Lawrence Berkeley National Laboratory, Berkeley, California 94143 1708, USA
    Int J Radiat Biol 85:923-8. 2009
  7. doi request reprint Cost-effectiveness analysis of intraoperative radiation therapy for early-stage breast cancer
    Michael D Alvarado
    Department of Surgery, UCSF Comprehensive Cancer Center, San Francisco, CA, USA
    Ann Surg Oncol 20:2873-80. 2013
  8. pmc Topographic enhancement mapping of the cancer-associated breast stroma using breast MRI
    Nima Nabavizadeh
    Department of Radiation Oncology, University of California, San Francisco Comprehensive Cancer Center, 1600 Divisadero Street H1031, San Francisco, CA 94143 1708, USA
    Integr Biol (Camb) 3:490-6. 2011
  9. pmc Beta1 integrin inhibition dramatically enhances radiotherapy efficacy in human breast cancer xenografts
    Catherine C Park
    Department of Radiation Oncology, University of California Comprehensive Cancer Center, San Francisco, CA 94143 1708, USA
    Cancer Res 68:4398-405. 2008
  10. pmc Breast cancer cells in three-dimensional culture display an enhanced radioresponse after coordinate targeting of integrin alpha5beta1 and fibronectin
    Jin Min Nam
    Life Sciences Division, Ernest Orlando Lawrence Berkeley National Laboratory, Berkeley, California, USA
    Cancer Res 70:5238-48. 2010

Collaborators

Detail Information

Publications14

  1. pmc Rapid and automated multidimensional fluorescence microscopy profiling of 3D human breast cultures
    Catherine C Park
    Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA
    Integr Biol (Camb) 5:681-91. 2013
    ..Such tools have therefore the potential to further characterize cell culture populations after cancer treatment and identify novel phenotypes of resistance...
  2. pmc β1 integrin mediates an alternative survival pathway in breast cancer cells resistant to lapatinib
    Catherine Huang
    Lester and Sue Smith Breast Center, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77054, USA
    Breast Cancer Res 13:R84. 2011
    ..The β1 integrin resides on the membrane of the breast cancer cell, activating several elements of breast tumor progression including proliferation and survival...
  3. doi request reprint American Society for Therapeutic Radiology and Oncology (ASTRO) Emerging Technology Committee report on electronic brachytherapy
    Catherine C Park
    Department of Radiation Oncology, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, 1600 Divisadero St, H1031, San Francisco, CA 94143 1708, USA
    Int J Radiat Oncol Biol Phys 76:963-72. 2010
    ..The full Emerging Technology Committee report is available on the American Society for Therapeutic Radiology and Oncology Web site...
  4. pmc NF-κB regulates radioresistance mediated by β1-integrin in three-dimensional culture of breast cancer cells
    Kazi Mokim Ahmed
    Department of Cancer and DNA Damage Responses, Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley
    Cancer Res 73:3737-48. 2013
    ..As β1-integrin also activates NF-κB, our findings reveal a novel forward feedback pathway that could be targeted to enhance therapy...
  5. pmc HER2 signaling pathway activation and response of breast cancer cells to HER2-targeting agents is dependent strongly on the 3D microenvironment
    Britta Weigelt
    Life Sciences Division, Lawrence Berkeley National Laboratory, University of California Berkeley, Mailstop 977R225A, 1 Cyclotron Road, Berkeley, CA 94720, USA
    Breast Cancer Res Treat 122:35-43. 2010
    ....
  6. doi request reprint beta1 integrin targeting to enhance radiation therapy
    Jin Min Nam
    Life Sciences Division, Ernest Orlando Lawrence Berkeley National Laboratory, Berkeley, California 94143 1708, USA
    Int J Radiat Biol 85:923-8. 2009
    ..In particular, beta1 integrin signaling has been implicated in the progression and metastasis of various cancers and has been shown to facilitate resistance to radiation therapy...
  7. doi request reprint Cost-effectiveness analysis of intraoperative radiation therapy for early-stage breast cancer
    Michael D Alvarado
    Department of Surgery, UCSF Comprehensive Cancer Center, San Francisco, CA, USA
    Ann Surg Oncol 20:2873-80. 2013
    ..We sought to analyze, from a societal perspective, the cost-effectiveness of two radiation strategies for early-stage invasive breast cancer: single-dose intraoperative radiation therapy (IORT) and the standard 6-week course of WB-EBRT...
  8. pmc Topographic enhancement mapping of the cancer-associated breast stroma using breast MRI
    Nima Nabavizadeh
    Department of Radiation Oncology, University of California, San Francisco Comprehensive Cancer Center, 1600 Divisadero Street H1031, San Francisco, CA 94143 1708, USA
    Integr Biol (Camb) 3:490-6. 2011
    ..Identification of a cancer-associated stroma may be further developed to help guide local therapy to reduce recurrence and morbidity in breast cancer patients...
  9. pmc Beta1 integrin inhibition dramatically enhances radiotherapy efficacy in human breast cancer xenografts
    Catherine C Park
    Department of Radiation Oncology, University of California Comprehensive Cancer Center, San Francisco, CA 94143 1708, USA
    Cancer Res 68:4398-405. 2008
    ....
  10. pmc Breast cancer cells in three-dimensional culture display an enhanced radioresponse after coordinate targeting of integrin alpha5beta1 and fibronectin
    Jin Min Nam
    Life Sciences Division, Ernest Orlando Lawrence Berkeley National Laboratory, Berkeley, California, USA
    Cancer Res 70:5238-48. 2010
    ..Our findings offer preclinical validation of fibronectin and alpha5beta1-integrin as targets for breast cancer therapy...
  11. doi request reprint Increasing the time to expander-implant exchange after postmastectomy radiation therapy reduces expander-implant failure
    Anne Warren Peled
    Division of Plastic Surgery, Department of Surgery, University of California, San Francisco, San Francisco, CA 94143, USA
    Plast Reconstr Surg 130:503-9. 2012
    ..The sequence and timing of tissue expansion and implant exchange with regard to postmastectomy radiation therapy may impact complication rates...
  12. doi request reprint High mammographic breast density is independent predictor of local but not distant recurrence after lumpectomy and radiotherapy for invasive breast cancer
    Catherine C Park
    Department of Radiation Oncology, University of California, San Francisco, School of Medicine, San Francisco, CA, USA
    Int J Radiat Oncol Biol Phys 73:75-9. 2009
    ..We hypothesized that the MBD might be a predictor of LRR after BCS and RT for invasive breast cancer...
  13. doi request reprint β1 integrin targeting potentiates antiangiogenic therapy and inhibits the growth of bevacizumab-resistant glioblastoma
    W Shawn Carbonell
    Department of Neurosurgery, University of California, San Francisco, San Francisco, CA 94143, USA
    Cancer Res 73:3145-54. 2013
    ..We concluded that β1 integrin upregulation in BRGs likely reflects an onset of hypoxia caused by antiangiogenic therapy, and that β1 inhibition is well tolerated in vivo as a tractable strategy to disrupt resistance to this therapy...
  14. pmc Beta1 integrin inhibitory antibody induces apoptosis of breast cancer cells, inhibits growth, and distinguishes malignant from normal phenotype in three dimensional cultures and in vivo
    Catherine C Park
    Departments of Radiation Oncology and Pathology, University of California San Francisco Mt Zion Cancer Center, 1600 Divisadero Street, San Francisco, CA 94143 1708, USA
    Cancer Res 66:1526-35. 2006
    ..Our findings indicate that beta(1) integrin is a promising therapeutic target, and that the three-dimensional lrECM culture assay can be used to effectively distinguish malignant and normal tissue response to therapy...