Research Topics
Species | M W ParizaSummaryAffiliation: University of Wisconsin Country: USA Publications
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Detail Information
Publications
Controlling acrylamide in French fry and potato chip models and a mathematical model of acrylamide formation: acrylamide: acidulants, phytate and calciumYeonhwa Park
Food Research Institute, University of Wisconsin Madison, 1925 Willow Dr, Madison, WI 53706, USA
Adv Exp Med Biol 561:343-56. 2005....- Conjugated linoleic acid may be useful in treating diabetes by controlling body fat and weight gainMichael W Pariza
Food Research Institute, Department of Food Microbiology and Toxicology, University of Wisconsin-Madison, Madison, Wisconsin 53706, USA
Diabetes Technol Ther 4:335-8. 2002 - Animal studies: summary, gaps, and future researchM W Pariza
Department of Food Microbiology and Toxicology, University of Wisconsin Madison 53706, USA
Am J Clin Nutr 66:1539S-1540S. 1997..The major knowledge gap, and our greatest challenge, is relating promising data from animal models and cell culture studies to the prevention of cancer in humans... - Conjugated linoleic acid and the control of cancer and obesityM W Pariza
Food Research Institute, Department of Food Microbiology and Toxicology, University of Wisconsin Madison, 53706 1187, USA
Toxicol Sci 52:107-10. 1999..Evidence is presented indicating that CLA may modulate cellular response to tumor necrosis factor-alpha (TNF-alpha). The mechanistic implications of this finding are considered... - Mechanisms of action of conjugated linoleic acid: evidence and speculationM W Pariza
Food Research Institute, Department of Food Microbiology, University of Wisconsin Madison, 53706, USA
Proc Soc Exp Biol Med 223:8-13. 2000.... - The biologically active isomers of conjugated linoleic acidM W Pariza
Department of Food Microbiology and Toxicology, Food Research Institute, University of Wisconsin Madison, 53706, USA
Prog Lipid Res 40:283-98. 2001..Presumably, CNA is metabolized differently than the 18-carbon CLA isomers, so this finding indicates direct activity of the administered compound as opposed to acting via a metabolite... - Evaluating the safety of microbial enzyme preparations used in food processing: update for a new centuryM W Pariza
Food Research Institute, Department of Food Microbiology and Toxicology, University of Wisconsin Madison, Madison, WI 53706, USA
Regul Toxicol Pharmacol 33:173-86. 2001..Under the criteria of the decision tree, no new food enzyme can enter the market without critical evaluation of its safety... - The effects of dietary conjugated nonadecadienoic acid on body composition in miceY Park
Food Research Institute, Department of Food Microbiology and Toxicology, University of Wisconsin--Madison, 53706, USA
Biochim Biophys Acta 1533:171-4. 2001..When fed to growing mice (0.3% of diet) CNA reduced body fat by 81% whereas CLA reduced body fat by 25%. CLA and CNA differ in length by one carbon atom so they are unlikely to share a common metabolite to account for these observations... - Regulation of stearoyl-CoA desaturase activity by the trans-10,cis-12 isomer of conjugated linoleic acid in HepG2 cellsY Choi
Department of Biochemistry, Food Research Institute, University of Wisconsin-Madison, Madison, Wisconsin 53706, USA
Biochem Biophys Res Commun 284:689-93. 2001..These results suggest that in HepG2 cells the trans-10,cis-12 CLA isomer regulates human SCD activity mainly by a posttranslational mechanism... - trans-10,cis-12-Conjugated linoleic acid reduces leptin secretion from 3T3-L1 adipocytesK Kang
Food Research Institute, Department of Food Microbiology and Toxicology, University of Wisconsin-Madison, 1925 Willow Drive, Madison, Wisconsin 53706, USA
Biochem Biophys Res Commun 287:377-82. 2001..These data provide new insights into apparent mechanistic similarities among t10c12 CLA, CNA, NDGA, and TZD... - Lipoxygenase inhibitors inhibit heparin-releasable lipoprotein lipase activity in 3T3-L1 adipocytes and enhance body fat reduction in mice by conjugated linoleic acidY Park
Department of Food Microbiology and Toxicology, Food Research Institute, University of Wisconsin-Madison, 53706, USA
Biochim Biophys Acta 1534:27-33. 2001..These findings appear to provide new perspectives and insights into the relationships between CLA, eicosanoids, the control of lipid accumulation in adipocytes, and effects of CLA on the immune system... - Comparison of methylation procedures for conjugated linoleic acid and artifact formation by commercial (trimethylsilyl) diazomethaneY Park
Food Research Institute, Department of Food Microbiology and Toxicology, University of Wisconsin-Madison, 1925 Willow Drive, Madison, WI 53706, USA
J Agric Food Chem 49:1158-64. 2001..Also, the method generated artifacts (trimethylsilyl CLA esters) and impurities (trimethylsilyl) that would interfere with short-chain fatty-acid analysis by GC... 
Determining the safety of enzymes used in animal feedMichael W Pariza
University of Wisconsin Madison, 1550 Linden Drive, Madison, WI 53706, USA
Regul Toxicol Pharmacol 56:332-42. 2010....- Perspective on the safety and effectiveness of conjugated linoleic acidMichael W Pariza
Food Research Institute, Department of Food Microbiology and Toxicology, University of Wisconsin Madison 53706, USA
Am J Clin Nutr 79:1132S-1136S. 2004..Experimental and clinical data relating to the safety and effectiveness of CLA in humans are presented and discussed... - Olive oil prevents the adverse effects of dietary conjugated linoleic acid on chick hatchability and egg qualityR Aydin
Animal Sciences Department, University of Wisconsin-Madison, 1675 Observatory Drive, Madison, WI 53706, USA
J Nutr 131:800-6. 2001..However, because the addition of olive oil also lowered egg CLA content, the direct role of egg CLA on egg hatchability and quality cannot be ruled out... - CLA reduces antigen-induced histamine and PGE(2) release from sensitized guinea pig tracheaeL D Whigham
Department of Nutritional Sciences, Madison, Wisconsin 53706, USA
Am J Physiol Regul Integr Comp Physiol 280:R908-12. 2001..CLA significantly reduced antigen-induced histamine and PGE(2) release. CLA appears to decrease release of some inflammatory mediators during type I hypersensitivity reactions... - Structure-activity relationship of conjugated linoleic acid and its cognates in inhibiting heparin-releasable lipoprotein lipase and glycerol release from fully differentiated 3T3-L1 adipocytesYeonhwa Park
Food Research Institute, University of Wisconsin-Madison, 1925 Willow Drive, Madison, WI 53706, USA
J Nutr Biochem 15:561-8. 2004..Accordingly the structural feature or features involved in regulating lipolysis appear to be more complex. Despite enhancing lipolysis in cultured 3T3-L1 adipocytes, trans-10 18:1 did not reduce body fat gain when fed to mice... - Dietary conjugated linoleic acid protects against end stage disease of systemic lupus erythematosus in the NZB/W F1 mouseM Yang
Department of Animal Science, University of Wisconsin-Madison, 53706-1284, USA
Immunopharmacol Immunotoxicol 22:433-49. 2000..Our data suggested that dietary CLA may accelerate the autoimmune symptoms of NZB/W F1 mice, however, CLA protected against the disease related body weight loss and prolonged survival after proteinuria... - trans-10,cis-12 CLA inhibits differentiation of 3T3-L1 adipocytes and decreases PPAR gamma expressionKihwa Kang
Department of Food Microbiology and Toxicology, Food Research Institute, University of Wisconsin, Madison, WI 53706, USA
Biochem Biophys Res Commun 303:795-9. 2003..These observations indicate that CLA decreases body fat gain in part by inhibiting the differentiation of preadipocytes... - Differential expression of hepatic stearoyl-CoA desaturase gene 1 in male and female miceK N Lee
Department of Nutritional Sciences, University of Wisconsin Madison 53706, USA
Biochim Biophys Acta 1304:85-8. 1996..The expression of the SCD1 mRNA is significantly higher in female compared to male mice and that this difference is accompanied by higher levels of palmitoleic and oleic acid in the livers of female mice... - Inhibition of stearoyl-CoA desaturase activity by the cis-9,trans-11 isomer and the trans-10,cis-12 isomer of conjugated linoleic acid in MDA-MB-231 and MCF-7 human breast cancer cellsYoungjin Choi
Department of Biochemistry, University of Wisconsin Madison, 53706, USA
Biochem Biophys Res Commun 294:785-90. 2002.... - Evidence that the anti-obesity effect of conjugated linoleic acid is independent of effects on stearoyl-CoA desaturase1 expression and enzyme activityKihwa Kang
Department of Food Microbiology and Toxicology, Food Research Institute, University of Wisconsin-Madison, Madison, WI 53706, USA
Biochem Biophys Res Commun 315:532-7. 2004.... - Short-term intake of conjugated linoleic acid inhibits lipoprotein lipase and glucose metabolism but does not enhance lipolysis in mouse adipose tissueXiaofang Xu
Food Research Institute, Department of Food Microbiology and Toxicology, University of Wisconsin-Madison, 53706, USA
J Nutr 133:663-7. 2003..In addition, CLA does not appear to enhance lipolysis in mouse adipose tissue in vivo... - Effects of conjugated linoleic acid (CLA) on immune responses, body composition and stearoyl-CoA desaturaseJames M Ntambi
Department of Biochemistry, Food Research Institute, University of Wisconsin-Madison, WI, USA
Can J Appl Physiol 27:617-28. 2002..In this review, we will focus on the effects of CLA on immune responses, body compositional changes and stearoyl-CoA desaturase... - Selective conjugated fatty acids inhibit guinea pig platelet aggregationGuangming Li
Molecular and Environmental Toxicology, University of Wisconsin-Madison, 53706, USA
Eur J Pharmacol 545:93-9. 2006.... - NF-kappaB independent inhibition of lipopolysaccharide-induced cyclooxygenase by a conjugated linoleic acid cognate, conjugated nonadecadienoic acidGuangming Li
Molecular and Environmental Toxicology, University of Wisconsin-Madison, 1675 Observatory Drive, Madison, WI 53706, USA
Biochim Biophys Acta 1761:969-72. 2006..The data indicate the regulation of COX-2 by select conjugated fatty acids and hence their anti-inflammatory actions could operate through different signal transduction pathways... - Influence of feeding soybean oil on conjugated linoleic acid content in beefTilak R Dhiman
Department of Animal, Dairy and Veterinary Sciences, Utah State University, 4815 Old Main Hill, Logan, UT 84322 4815, USA
J Agric Food Chem 53:684-9. 2005..Supplementing SO increased C(18:2) trans-10, cis-12 CLA in adipose tissue of the LD. Supplementing high-grain finishing diets with SO is not an effective strategy to enhance the C(18:2) cis-9, trans-11 isomer of CLA in beef... - Biological activities of conjugated fatty acids: conjugated eicosadienoic (conj. 20:2delta(c11,t13/t12,c14)), eicosatrienoic (conj. 20:3delta(c8,t12,c14)), and heneicosadienoic (conj. 21:2delta(c12,t14/c13,t15)) acids and other metabolites of conjugated lYeonhwa Park
Department of Food Science, University of Massachusetts, 100 Holdsworth Way, Amherst, MA 01003, USA
Biochim Biophys Acta 1687:120-9. 2005..This is the first work to report the presence of conjugated 12 and 14 carbon fatty acids, originated from CLA, and the biological activities of CEA, CETA and CHDA... - Effects of conjugated linoleic acid on long term feeding in Fischer 344 ratsYeonhwa Park
Department of Food Science, University of Massachusetts, 100 Holdsworth Way, Amherst, MA 01003, United States
Food Chem Toxicol 43:1273-9. 2005..Although this study used a limited number of animals and a single dose of CLA, our results suggest that long term CLA feeding did not cause any adverse effects in rats... - Conjugated linoleic acid preserves gastrocnemius muscle mass in mice bearing the colon-26 adenocarcinomaErin Graves
National Institute of Nursing Research, National Institutes of Health, Bethesda, MD, USA
Res Nurs Health 28:48-55. 2005..CLA preserved gastrocnemius muscle mass and reduced TNF receptors in muscle of tumor-bearing mice. These data suggest that CLA may preserve muscle mass by reducing the catabolic effects of TNF on skeletal muscle...