A Parachikova

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc Exercise alters the immune profile in Tg2576 Alzheimer mice toward a response coincident with improved cognitive performance and decreased amyloid
    Kathryn E Nichol
    Institute for Brain Aging and Dementia, University of California, Irvine, Irvine, CA, USA
    J Neuroinflammation 5:13. 2008
  2. pmc Inflammatory changes parallel the early stages of Alzheimer disease
    A Parachikova
    Institute for Brain Aging and Dementia, University of California, 1113 Gillespie Neuroscience Research Facility, Irvine, CA 92697 4540, USA
    Neurobiol Aging 28:1821-33. 2007
  3. pmc Reduced CXCL12/CXCR4 results in impaired learning and is downregulated in a mouse model of Alzheimer disease
    A Parachikova
    Institute for Brain Aging and Dementia, University of California, 1113 Gillespie Neuroscience Research Facility, Irvine, CA 92697 4540, USA
    Neurobiol Dis 28:143-53. 2007
  4. pmc Short-term exercise in aged Tg2576 mice alters neuroinflammation and improves cognition
    A Parachikova
    Institute for Brain Aging and Dementia, University of California, Irvine, Irvine, CA 92697 4540, USA
    Neurobiol Dis 30:121-9. 2008

Collaborators

Detail Information

Publications4

  1. pmc Exercise alters the immune profile in Tg2576 Alzheimer mice toward a response coincident with improved cognitive performance and decreased amyloid
    Kathryn E Nichol
    Institute for Brain Aging and Dementia, University of California, Irvine, Irvine, CA, USA
    J Neuroinflammation 5:13. 2008
    ..Our objective was to determine if exercise could induce a shift from the immune profile in aged (17-19 months) Tg2576 mice to a response that reduces Abeta pathology...
  2. pmc Inflammatory changes parallel the early stages of Alzheimer disease
    A Parachikova
    Institute for Brain Aging and Dementia, University of California, 1113 Gillespie Neuroscience Research Facility, Irvine, CA 92697 4540, USA
    Neurobiol Aging 28:1821-33. 2007
    ..In conclusion, transition into AD dementia correlates with increased MHC II(+) microglia-mediated immunity and is paradoxically paralleled by a decrease in T cell number, suggesting immune dysfunction...
  3. pmc Reduced CXCL12/CXCR4 results in impaired learning and is downregulated in a mouse model of Alzheimer disease
    A Parachikova
    Institute for Brain Aging and Dementia, University of California, 1113 Gillespie Neuroscience Research Facility, Irvine, CA 92697 4540, USA
    Neurobiol Dis 28:143-53. 2007
    ..Treated animals showed selectively impaired learning and memory suggesting a potential role for this chemokine in cognitive functioning...
  4. pmc Short-term exercise in aged Tg2576 mice alters neuroinflammation and improves cognition
    A Parachikova
    Institute for Brain Aging and Dementia, University of California, Irvine, Irvine, CA 92697 4540, USA
    Neurobiol Dis 30:121-9. 2008
    ..Notably, exercising Tg2576 exhibited increases in a few markers including CXCL1 and CXCL12, two chemokines that may affect cognition...