Demosthenes Pappagianis

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi Coccidioidomycosis in California state correctional institutions
    Demosthenes Pappagianis
    School of Medicine, University of California, Davis, Davis, CA 95616, USA
    Ann N Y Acad Sci 1111:103-11. 2007
  2. ncbi Characteristics of the protective subcellular coccidioidal T27K vaccine
    Suzanne M Johnson
    Department of Medical Microbiology and Immunology, School of Medicine, University of California, Davis, CA 95616, USA
    Ann N Y Acad Sci 1111:275-89. 2007
  3. doi Molecular cloning, characterization and expression analysis of two beta-N-acetylhexosaminidase homologs of Coccidioides posadasii
    Jennine M Lunetta
    Department of Medical Microbiology and Immunology, School of Medicine, University of California, Davis, California 95616, USA
    Med Mycol 48:744-56. 2010
  4. ncbi Molecular cloning and expression of a cDNA encoding a Coccidioides posadasii Cu,Zn superoxide dismutase identified by proteomic analysis of the coccidioidal T27K vaccine
    Jennine M Lunetta
    Department of Medical Microbiology and Immunology, School of Medicine, University of California, Davis, California 95616, USA
    Ann N Y Acad Sci 1111:181-97. 2007
  5. pmc Amplification of coccidioidal DNA in clinical specimens by PCR
    Suzanne M Johnson
    Department of Medical Microbiology and Immunology, School of Medicine, University of California Davis, Davis, California 95616, USA
    J Clin Microbiol 42:1982-5. 2004
  6. ncbi Molecular cloning and expression of a cDNA encoding a Coccidioides posadasii 1,2-alpha-mannosidase identified in the coccidioidal T27K vaccine by immunoproteomic methods
    Jennine M Lunetta
    Department of Medical Microbiology and Immunology, School of Medicine, University of California, Davis, CA 95616, USA
    Ann N Y Acad Sci 1111:164-80. 2007
  7. ncbi Safety, antigenicity, and efficacy of a recombinant coccidioidomycosis vaccine in cynomolgus macaques (Macaca fascicularis)
    Suzanne M Johnson
    D V M M P V M, California National Primate Research Center, University of California, Davis, CA 95616, USA
    Ann N Y Acad Sci 1111:290-300. 2007
  8. ncbi Clinical, clinicopathologic, and radiographic findings in dogs with coccidioidomycosis: 24 cases (1995-2000)
    Lynelle R Johnson
    Department of Veterinary Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, CA 95616, USA
    J Am Vet Med Assoc 222:461-6. 2003
  9. ncbi Coccidioides niches and habitat parameters in the southwestern United States: a matter of scale
    Frederick S Fisher
    Department of Geosciences, University of Arizona, Tucson, AZ 85719, USA
    Ann N Y Acad Sci 1111:47-72. 2007
  10. ncbi Comparison of Coccidioides immitis serological antibody titres between forms of clinical coccidioidomycosis in horses
    Jill C Higgins
    Loomis Basin Large Animal Services, Loomis, CA 95650, USA
    Vet J 173:118-23. 2007

Collaborators

Detail Information

Publications19

  1. ncbi Coccidioidomycosis in California state correctional institutions
    Demosthenes Pappagianis
    School of Medicine, University of California, Davis, Davis, CA 95616, USA
    Ann N Y Acad Sci 1111:103-11. 2007
    ..Estimates of the cost per patient have varied from $8,000 in the 1990s to $30,000 more recently. Thus, this disease has important medical, demographic, and financial implications for the state...
  2. ncbi Characteristics of the protective subcellular coccidioidal T27K vaccine
    Suzanne M Johnson
    Department of Medical Microbiology and Immunology, School of Medicine, University of California, Davis, CA 95616, USA
    Ann N Y Acad Sci 1111:275-89. 2007
    ..This appears unrelated to the aging of the mice. Prolongation of the protective action may require addition of a different adjuvant or administration of booster doses of vaccine...
  3. doi Molecular cloning, characterization and expression analysis of two beta-N-acetylhexosaminidase homologs of Coccidioides posadasii
    Jennine M Lunetta
    Department of Medical Microbiology and Immunology, School of Medicine, University of California, Davis, California 95616, USA
    Med Mycol 48:744-56. 2010
    ..Both the CpHEX1 and CpHEX2 cDNAs were expressed as recombinant fusion proteins and purified under denaturing conditions to apparent homogeneity but they lacked enzymatic activity...
  4. ncbi Molecular cloning and expression of a cDNA encoding a Coccidioides posadasii Cu,Zn superoxide dismutase identified by proteomic analysis of the coccidioidal T27K vaccine
    Jennine M Lunetta
    Department of Medical Microbiology and Immunology, School of Medicine, University of California, Davis, California 95616, USA
    Ann N Y Acad Sci 1111:181-97. 2007
    ..Activity assays performed with native PAGE gels of the T27K vaccine showed that the vaccine contains superoxide dismutase. The cDNA encoding the enzyme has been cloned and sequenced and expressed as a recombinant protein...
  5. pmc Amplification of coccidioidal DNA in clinical specimens by PCR
    Suzanne M Johnson
    Department of Medical Microbiology and Immunology, School of Medicine, University of California Davis, Davis, California 95616, USA
    J Clin Microbiol 42:1982-5. 2004
    ..A 239-bp product was visualized when 10 fg of exogenous coccidioidal DNA was subjected to amplification. This product was demonstrated in some human and mouse sera prior to the detection of coccidioidal antibodies...
  6. ncbi Molecular cloning and expression of a cDNA encoding a Coccidioides posadasii 1,2-alpha-mannosidase identified in the coccidioidal T27K vaccine by immunoproteomic methods
    Jennine M Lunetta
    Department of Medical Microbiology and Immunology, School of Medicine, University of California, Davis, CA 95616, USA
    Ann N Y Acad Sci 1111:164-80. 2007
    ..Class I 1,2-alpha-mannosidase enzyme activity was also detected in the T27K vaccine using the substrate, Man-alpha-1,2-Man-alpha-OCH(3) in a spectrophotometric assay...
  7. ncbi Safety, antigenicity, and efficacy of a recombinant coccidioidomycosis vaccine in cynomolgus macaques (Macaca fascicularis)
    Suzanne M Johnson
    D V M M P V M, California National Primate Research Center, University of California, Davis, CA 95616, USA
    Ann N Y Acad Sci 1111:290-300. 2007
    ..Additional experiments may be needed to optimize the vaccination and to confer greater protection against lethal challenge...
  8. ncbi Clinical, clinicopathologic, and radiographic findings in dogs with coccidioidomycosis: 24 cases (1995-2000)
    Lynelle R Johnson
    Department of Veterinary Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, CA 95616, USA
    J Am Vet Med Assoc 222:461-6. 2003
    ..To determine clinical, clinicopathologic, and radiographic abnormalities in dogs with coccidioidomycosis...
  9. ncbi Coccidioides niches and habitat parameters in the southwestern United States: a matter of scale
    Frederick S Fisher
    Department of Geosciences, University of Arizona, Tucson, AZ 85719, USA
    Ann N Y Acad Sci 1111:47-72. 2007
    ..Coccidioides has persisted in the soil at a site in Dinosaur National Monument, Utah for 37 years and at a Tucson, Arizona site for 41 years...
  10. ncbi Comparison of Coccidioides immitis serological antibody titres between forms of clinical coccidioidomycosis in horses
    Jill C Higgins
    Loomis Basin Large Animal Services, Loomis, CA 95650, USA
    Vet J 173:118-23. 2007
    ..Measurement of serological titre may be a useful diagnostic aid in establishing form and severity of disease and thus inform prognosis...
  11. ncbi Seroprevalence of antibodies against Coccidioides immitis in healthy horses
    Jill C Higgins
    Arizona Equine Medical and Surgical Center, 1685 S Gilbert Rd, Gilbert, AZ 85296, USA
    J Am Vet Med Assoc 226:1888-92. 2005
    ..To determine the seroprevalence of antibodies against Coccidioides immitis in healthy horses residing in an area in which the organism is endemic...
  12. pmc Seroincidence of Coccidioidomycosis during military desert training exercises
    Nancy F Crum
    Infectious Disease Division, Clinical Investigation Department, Naval Medical Center San Diego, San Diego, California 92134 1005, USA
    J Clin Microbiol 42:4552-5. 2004
    ..Due to the potential morbidity and mortality of this infection, preventative strategies, including vaccine development, are advocated...
  13. pmc Preliminary evaluation of whole-blood gamma interferon release for clinical assessment of cellular immunity in patients with active coccidioidomycosis
    Neil M Ampel
    Medicine and Primary Care 1 111, Southern Arizona Veterans Affairs Health Care System, 3601 S Sixth Avenue, Tucson, AZ 85723, USA
    Clin Diagn Lab Immunol 12:700-4. 2005
    ..59; P < 0.01). These results suggest that the IFN-gamma release assay with T27K as the antigen may be a useful clinical test for assessing cellular immunity in patients with active coccidioidomycosis...
  14. pmc The mannose receptor mediates the cellular immune response in human coccidioidomycosis
    Neil M Ampel
    Department of Medicine, University of Arizona Health Sciences Center, Tucson, Arizona, USA
    Infect Immun 73:2554-5. 2005
    ..These data suggest that MR mediates IL-2 release by T27K...
  15. ncbi Risk factors for mammary candidosis among lactating women
    Jimi Francis Morrill
    Department of Biochemistry, University of Nevada Reno, Reno, NV 89557, USA
    J Obstet Gynecol Neonatal Nurs 34:37-45. 2005
    ..To document the occurrence of Candida colonization and mammary candidosis among lactating women, risk factors for Candida colonization, and the relationship between Candida colonization and breastfeeding at 9 weeks postpartum...
  16. ncbi Donor-related coccidioidomycosis in organ transplant recipients
    Patty W Wright
    University of Alabama at Birmingham, Birmingham, AL 35294 0006, USA
    Clin Infect Dis 37:1265-9. 2003
    ..immitis is endemic. Both subjects had received a transplanted organ from the same donor, an individual with unrecognized active coccidioidomycosis at the time of his death...
  17. ncbi A murine model of coccidioidal meningitis
    Perparim Kamberi
    California Institute for Medical Research and Department of Medicine, Division of Infectious Diseases, Santa Clara Valley Medical Center, San Jose, California 95128, USA
    J Infect Dis 187:453-60. 2003
    ..With the development of these models, studies of pathogenesis, host response, and therapy are possible...
  18. pmc In vitro whole-blood analysis of cellular immunity in patients with active coccidioidomycosis by using the antigen preparation T27K
    Neil M Ampel
    Medicine and Primary Care Service, Southern Arizona Veterans Affairs Health Care System, Tucson, Arizona 85723, USA
    Clin Diagn Lab Immunol 9:1039-43. 2002
    ..001), but not for IL-4, IL-5, or IL-10. These data indicate that in vitro assessment of CD69 expression on T lymphocytes by using T27K may be a useful measure of cellular immune response among subjects with active coccidioidomycosis...
  19. pmc Efficacy of intravenous liposomal amphotericin B (AmBisome) against coccidioidal meningitis in rabbits
    Karl V Clemons
    Department of Medicine, Division of Infectious Diseases, Santa Clara Valley Medical Center, California Institute for Medical Research, 751 South Bascom Avenue, San Jose, CA 95128, USA
    Antimicrob Agents Chemother 46:2420-6. 2002
    ..These data indicate that AmBi may offer an improvement in the treatment of coccidioidal meningitis. Additional studies are warranted...