John C Papadimitriou

Summary

Affiliation: University of Maryland
Country: USA

Publications

  1. ncbi request reprint Histologic grading of acute allograft rejection in pancreas needle biopsy: correlation to serum enzymes, glycemia, and response to immunosuppressive treatment
    J C Papadimitriou
    Department of Pathology, University of Maryland School of Medicine, Baltimore 21201, USA
    Transplantation 66:1741-5. 1998
  2. doi request reprint Antibody-mediated allograft rejection: morphologic spectrum and serologic correlations in surveillance and for cause biopsies
    John C Papadimitriou
    Department of Pathology, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    Transplantation 95:128-36. 2013
  3. doi request reprint Glomerular inflammation in renal allografts biopsies after the first year: cell types and relationship with antibody-mediated rejection and graft outcome
    John C Papadimitriou
    Department of Pathology, University of Maryland School of Medicine, Baltimore, MD, USA
    Transplantation 90:1478-85. 2010
  4. ncbi request reprint Histological grading of chronic pancreas allograft rejection/graft sclerosis
    John C Papadimitriou
    Department of Pathology, University of Maryland, School of Medicine, Baltimore MD, USA
    Am J Transplant 3:599-605. 2003
  5. ncbi request reprint Polyomavirus BK versus JC replication and nephropathy in renal transplant recipients: a prospective evaluation
    Cinthia B Drachenberg
    Department of Pathology, Medicine and Pediatrics, University of Maryland, School of Medicine, Baltimore, MD 21201, USA
    Transplantation 84:323-30. 2007
  6. ncbi request reprint Histological patterns of polyomavirus nephropathy: correlation with graft outcome and viral load
    Cinthia B Drachenberg
    Department of Pathology, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    Am J Transplant 4:2082-92. 2004
  7. doi request reprint BK virus-associated urinary bladder carcinoma in transplant recipients: report of 2 cases, review of the literature, and proposed pathogenetic model
    Borislav A Alexiev
    Department of Pathology, University of Maryland Medical Center, Baltimore, MD 21201, USA
    Hum Pathol 44:908-17. 2013
  8. doi request reprint Polyomavirus (BK)-associated pleomorphic giant cell carcinoma of the urinary bladder: a case report
    Borislav A Alexiev
    Department of Pathology, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    Pathol Res Pract 209:255-9. 2013
  9. ncbi request reprint Polyomavirus disease in renal transplantation: review of pathological findings and diagnostic methods
    Cinthia B Drachenberg
    Department of Pathology, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    Hum Pathol 36:1245-55. 2005
  10. ncbi request reprint Negative impact of human leukocyte antigen matching in the outcome of polyomavirus nephropathy
    Cinthia B Drachenberg
    Department of Pathology, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    Transplantation 80:276-8. 2005

Collaborators

Detail Information

Publications47

  1. ncbi request reprint Histologic grading of acute allograft rejection in pancreas needle biopsy: correlation to serum enzymes, glycemia, and response to immunosuppressive treatment
    J C Papadimitriou
    Department of Pathology, University of Maryland School of Medicine, Baltimore 21201, USA
    Transplantation 66:1741-5. 1998
    ..The correlation between clinical evidence of graft dysfunction (increased serum enzymes and glucose), severity of acute rejection on biopsy (rejection grade), and response to treatment has not been previously studied...
  2. doi request reprint Antibody-mediated allograft rejection: morphologic spectrum and serologic correlations in surveillance and for cause biopsies
    John C Papadimitriou
    Department of Pathology, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    Transplantation 95:128-36. 2013
    ..Subclinical antibody-mediated allograft rejection (AMR) has been characterized in serial biopsies from presensitized recipients but has not been systematically studied in conventional renal transplants...
  3. doi request reprint Glomerular inflammation in renal allografts biopsies after the first year: cell types and relationship with antibody-mediated rejection and graft outcome
    John C Papadimitriou
    Department of Pathology, University of Maryland School of Medicine, Baltimore, MD, USA
    Transplantation 90:1478-85. 2010
    ..The role of glomerular inflammation (GI) components in the development of TG and their impact on outcome are incompletely understood...
  4. ncbi request reprint Histological grading of chronic pancreas allograft rejection/graft sclerosis
    John C Papadimitriou
    Department of Pathology, University of Maryland, School of Medicine, Baltimore MD, USA
    Am J Transplant 3:599-605. 2003
    ..87), substantial for Grade CII (0.61) and moderate for Grade CI (0.59). The proposed grading scheme provides a reliable and reproducible tool for the assessment of CR in percutaneous needle biopsies, with definite prognostic significance...
  5. ncbi request reprint Polyomavirus BK versus JC replication and nephropathy in renal transplant recipients: a prospective evaluation
    Cinthia B Drachenberg
    Department of Pathology, Medicine and Pediatrics, University of Maryland, School of Medicine, Baltimore, MD 21201, USA
    Transplantation 84:323-30. 2007
    ..Few cases of PVAN have been attributed to JCV. Systematic studies on JCV replication in KT are lacking...
  6. ncbi request reprint Histological patterns of polyomavirus nephropathy: correlation with graft outcome and viral load
    Cinthia B Drachenberg
    Department of Pathology, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    Am J Transplant 4:2082-92. 2004
    ..0002, 0.0001 and 0.0006). Due to the focal nature of PVAN, correlation of biopsy results with viruria and viremia are required for diagnosis...
  7. doi request reprint BK virus-associated urinary bladder carcinoma in transplant recipients: report of 2 cases, review of the literature, and proposed pathogenetic model
    Borislav A Alexiev
    Department of Pathology, University of Maryland Medical Center, Baltimore, MD 21201, USA
    Hum Pathol 44:908-17. 2013
    ..We propose a model of changes ranging from viral reactivation to dysplasia to invasive carcinoma. Clinical vigilance is warranted for early diagnosis of BK polyomavirus-related urothelial malignancies in transplant recipients...
  8. doi request reprint Polyomavirus (BK)-associated pleomorphic giant cell carcinoma of the urinary bladder: a case report
    Borislav A Alexiev
    Department of Pathology, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    Pathol Res Pract 209:255-9. 2013
    ....
  9. ncbi request reprint Polyomavirus disease in renal transplantation: review of pathological findings and diagnostic methods
    Cinthia B Drachenberg
    Department of Pathology, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    Hum Pathol 36:1245-55. 2005
    ..Also discussed in the context of their clinical significance are the main virological and epidemiological aspects of the BK, JC, and SV40 polyomavirus infections...
  10. ncbi request reprint Negative impact of human leukocyte antigen matching in the outcome of polyomavirus nephropathy
    Cinthia B Drachenberg
    Department of Pathology, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    Transplantation 80:276-8. 2005
    ..An adequately developed antiviral cellular immunity may lead to significant tissue damage and graft loss even if the viral infection is eventually controlled...
  11. ncbi request reprint Histologic versus molecular diagnosis of BK polyomavirus-associated nephropathy: a shifting paradigm?
    Cinthia B Drachenberg
    Department of Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    Clin J Am Soc Nephrol 1:374-9. 2006
    ..Evaluation of a renal biopsy for the purpose of staging is important for prognosis and is also of paramount importance for the rational assessment of therapeutic success...
  12. doi request reprint Histopathology of chronic rejection in a nonhuman primate model of vascularized composite allotransplantation
    Gerhard S Mundinger
    Division of Plastic and Reconstructive Surgery, R Adams Cowley Shock Trauma Center, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    Transplantation 95:1204-10. 2013
    ..Although intimal hyperplasia has been reported in human hand transplants, chronic changes in VCAs remain poorly described...
  13. ncbi request reprint Pancreas allograft biopsy: safety of percutaneous biopsy-results of a large experience
    David K Klassen
    Department of Medicine, University of Maryland School of Medicine, 22 S Greene Street, Baltimore, MD 21201, USA
    Transplantation 73:553-5. 2002
    ..The safety and success rate of the procedure with current surgical techniques is unclear. We report the complications and success rate in 426 consecutive percutaneous pancreas allograft biopsies performed at a single center...
  14. doi request reprint Granulomatous foreign-body reaction involving oral and perioral tissues after injection of biomaterials: a series of 7 cases and review of the literature
    Bruno C Jham
    Department of Diagnostic Sciences and Pathology, University of Maryland Dental School, Baltimore, MD 21201, USA
    J Oral Maxillofac Surg 67:280-5. 2009
    ..In addition, the clinical and epidemiological profile of this condition is summarized, based on a review of the English-language literature of all previously described cases...
  15. ncbi request reprint Retransplantation in patients with graft loss caused by polyoma virus nephropathy
    Emilio Ramos
    Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA
    Transplantation 77:131-3. 2004
    ..The risk of recurrence does not seem to be increased in comparison with the first graft...
  16. ncbi request reprint BK polyoma virus allograft nephropathy: ultrastructural features from viral cell entry to lysis
    Cinthia B Drachenberg
    Department of Pathology, University of Maryland School of Medicine, Baltimore, MD, USA
    Am J Transplant 3:1383-92. 2003
    ..The observed ultrastructural interactions between the BK virions and host cells are remarkably similar to viral cell entry and nuclear targeting described for SV40 virus...
  17. ncbi request reprint MIC expression in renal and pancreatic allografts
    Kim G Hankey
    Department of Pathology, University of Maryland Medical System, Baltimore, Maryland 21201, USA
    Transplantation 73:304-6. 2002
    ..In this study, we report the expression of MICA and MICB in renal and pancreatic allograft biopsies, which were obtained due to clinical signs of rejection...
  18. ncbi request reprint Histologic features of mycophenolate mofetil-related colitis: a graft-versus-host disease-like pattern
    John C Papadimitriou
    Department of Pathology, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    Int J Surg Pathol 11:295-302. 2003
    ..This form of injury could be related to either direct toxicity or an "innocent by-stander" phenomenon secondary to the alteration of the immunologic microenvironment of the colon caused by the MMF...
  19. doi request reprint Distinctive morphological features of antibody-mediated and T-cell-mediated acute rejection in pancreas allograft biopsies
    John C Papadimitriou
    Department of Pathology, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    Curr Opin Organ Transplant 17:93-9. 2012
    ..In pancreas allografts the contrasting morphological features of these entities have only recently been described...
  20. ncbi request reprint Clinical course of polyoma virus nephropathy in 67 renal transplant patients
    Emilio Ramos
    Departments of Medicine, Pathology, Pharmacy Services, and Surgery, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA
    J Am Soc Nephrol 13:2145-51. 2002
    ..Although multiple factors probably play a role in the development of PVN, judicious use of immunosuppressive agents is indicated to minimize the occurrence of this infection...
  21. doi request reprint Endothelial injury in renal antibody-mediated allograft rejection: a schematic view based on pathogenesis
    Cinthia B Drachenberg
    Department of Pathology, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    Transplantation 95:1073-83. 2013
    ..The vast array of EC responses provides great opportunities for intervention but also represents a colossal challenge for the development of universally successful therapies...
  22. doi request reprint Metastatic neuroendocrine carcinomas to the head and neck: report of 4 cases and review of the literature
    Andrew R Salama
    Department of Oral and Maxillofacial Surgery, University of Maryland Dental School, University of Maryland Medical Center, Marlene and Stuart Greenebaum Cancer Center, Baltimore, MD 21201, USA
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 108:242-7. 2009
    ..Although rare, these tumors should be included in the differential diagnosis of head and neck lesions, particularly when the patient presents with a history of a previous NEC...
  23. ncbi request reprint Urethral stromal tumor with pacemaker cell phenotype
    William A Kanner
    Department of Pathology, University of Maryland School of Medicine, Baltimore, Maryland, USA
    Ultrastruct Pathol 31:63-71. 2007
    ..Interstitial cells with potential pacemaker function have been recently described in the lower urinary tract, including the urethra, and this tumor may be related to this cellular phenotype...
  24. ncbi request reprint The inflamed pancreas transplant: histological differential diagnosis
    Cinthia B Drachenberg
    Department of Pathology, University of Maryland School of Medicine, Baltimore, Maryland, USA
    Semin Diagn Pathol 21:255-9. 2004
    ..Although in many ways the morphological features of these processes overlap, there are also important differences that can help the pathologist to reach the correct diagnosis...
  25. ncbi request reprint T cell TRAIL promotes murine lupus by sustaining effector CD4 Th cell numbers and by inhibiting CD8 CTL activity
    Violeta Rus
    Research Service, Department of Veterans Affairs Medical Center, Baltimore, MD 21201, USA
    J Immunol 178:3962-72. 2007
    ....
  26. ncbi request reprint Multifocal melanoacanthoma of the gingiva and hard palate
    John K Brooks
    Department of Oncology and Diagnostic Sciences, Baltimore College of Dental Surgery, Dental School, University of Maryland, Baltimore, 650 W Baltimore St, Baltimore, MD 21201 1586, USA
    J Periodontol 80:527-32. 2009
    ..This article reports a previously undescribed case of multifocal melanoacanthoma affecting the maxillary and mandibular gingiva and the hard palate. A literature review of melanoacanthoma of the gingiva is also provided...
  27. ncbi request reprint Graft dysfunction in pancreas and islet transplantation: morphological aspects
    Cinthia B Drachenberg
    Department of Pathology, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA
    Curr Opin Organ Transplant 16:106-9. 2011
    ..In search of these ambitious and only partially achieved objectives, continuous advances are made in the field...
  28. ncbi request reprint Intraoral proliferative myositis: case report and literature review
    John K Brooks
    Department of Diagnostic Sciences and Pathology, University of Maryland Dental School, Baltimore, Maryland, USA
    Head Neck 29:416-20. 2007
    ..Here we present only the third oral case of proliferative myositis, arising from the tongue of a 65-year-old man...
  29. ncbi request reprint Spontaneous cutaneous ulcers in a patient with a moderate degree of chronic kidney disease: a different spectrum of calciphylaxis
    Wassim A Hitti
    School of Medicine, University of Maryland, 1 East University Parkway, Baltimore, MD 21218, USA
    Scand J Urol Nephrol 42:181-3. 2008
    ..We conclude that calciphylaxis should be considered in the differential diagnosis of skin ulcerations in patients with any degree of CKD...
  30. ncbi request reprint Oral inflammatory myofibroblastic tumor demonstrating ALK, p53, MDM2, CDK4, pRb, and Ki-67 immunoreactivity in an elderly patient
    John K Brooks
    Department of Diagnostic Sciences and Pathology, University of Maryland Dental School, 666 West Baltimore Street, Baltimore, MD 21201 1586, USA
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 99:716-26. 2005
    ..The recorded positivity for ALK, p53, MDM2, CDK4, pRb, and Ki-67, despite the absence of bcl-2 reactivity, strongly favors the neoplastic origin of the studied tumor...
  31. ncbi request reprint Basal cell adenocarcinoma of the oral minor salivary glands: review of the literature and presentation of two cases
    Pallavi Parashar
    Department of Diagnostic Sciences and Pathology, University of Maryland, Baltimore, 666 West Baltimore St, Baltimore, MD 21201, USA
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 103:77-84. 2007
    ..Immunohistochemical studies may complement a thorough histopathologic analysis in discriminating BCA from other salivary gland tumors...
  32. ncbi request reprint Both apoptosis and complement membrane attack complex deposition are major features of murine acute graft-vs.-host disease
    Florin Niculescu
    Department of Medicine, Division of Rheumatology and Clinical Immunology, Baltimore, MD 21201, USA
    Exp Mol Pathol 79:136-45. 2005
    ..These results indicate a role for both adaptive immunity and innate immunity in this model of GVHD and support its use in modeling human acute GVHD in the nonmyeloablative setting...
  33. pmc Full-length IL-33 promotes inflammation but not Th2 response in vivo in an ST2-independent fashion
    Irina G Luzina
    Division of Rheumatology and Clinical Immunology, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    J Immunol 189:403-10. 2012
    ..The different effects of these isoforms, particularly the pro-Th2 effects of mature IL-33, are due to differential utilization of the IL-33R chain ST2, whereas their similar effects result from regulation of gene expression...
  34. ncbi request reprint Synchronous occurrence of ipsilateral synovial chondromatosis of the temporomandibular joint and pleomorphic adenoma of the parotid gland
    Eleni Sarlani
    Department of Biomedical Sciences, Brotman Facial Pain Center, Dental School, University of Maryland, 666 W Baltimore Street, Room 2 A 15, Baltimore, MD 21201 1586, USA
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 98:69-75. 2004
    ..However, to the best of our knowledge, this is the first time that true synchronous occurrence of ipsilateral SC and pleomorphic adenoma, or parotid tumor of any kind, is reported...
  35. doi request reprint Cutaneous ciliated cyst: a case report with focus on mullerian heterotopia and comparison with eccrine sweat glands
    William W Bivin
    Departments of Pathology, University of Maryland Medical System, Baltimore, 21201, USA
    Am J Dermatopathol 32:731-4. 2010
    ..The histologic, immunohistochemical, and ultrastructural findings of this case and the literature provide evidence in favor of the Mullerian heterotopia theory...
  36. ncbi request reprint Induction of prolonged infiltration of T lymphocytes and transient T lymphocyte-dependent collagen deposition in mouse lungs following adenoviral gene transfer of CCL18
    Irina G Luzina
    University of Maryland School of Medicine, and Baltimore VA Medical Center, Baltimore, Maryland 21201, USA
    Arthritis Rheum 54:2643-55. 2006
    ..We sought to determine whether CCL18 alone can induce pulmonary T lymphocytic infiltration and fibrosis in mouse lungs...
  37. ncbi request reprint Schistocytes, echinocytes, iron deficiency anemia, and thrombocytopenia - hematologic manifestations of splenic angiosarcoma
    Paula Rosenblatt
    University of Maryland School of Medicine, Marlene and Stewart Greenebaum Cancer Center, Baltimore, USA
    Arch Iran Med 16:602-5. 2013
    ..We present a literature review on the hematologic manifestations that is associated with this malignant disease. ..
  38. doi request reprint Canalicular adenoma--search for the cell of origin: ultrastructural and immunohistochemical analysis of 7 cases and review of the literature
    Thomas A Huebner
    Department of Pathology, University of Maryland Medical Center, Baltimore, Maryland, USA and
    Ultrastruct Pathol 38:74-82. 2014
    ..Their morphologic, immunohistochemical, and ultrastructural findings support a cell of origin demonstrating features of both the intercalated duct cells and the striated duct luminal epithelial cells...
  39. doi request reprint Metastatic carcinoma within a foreign-body reaction to vegetable matter: a pseudo-pseudomalignancy
    Jennifer M Reese
    Department of Pathology University of Maryland School of Medicine, Baltimore, Maryland 21201, USA
    Int J Surg Pathol 16:59-61. 2008
  40. ncbi request reprint Adrenal cortical adenoma with excess black pigment deposition, combined with myelolipoma and clinical Cushing's syndrome
    Ray Armand
    Department of Pathology, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA
    Int J Surg Pathol 12:57-61. 2004
    ..Co-occurrence of a functional black adenoma and a well-developed myelolipoma has not been reported in the literature. We describe the significant findings of this case, together with a review of the literature...
  41. ncbi request reprint Immunohistochemical studies in the differential diagnosis of small round cell soft tissue tumors
    John C Papadimitriou
    University of Maryland, Department of Pathology, Maryland 21201 1595, USA
    Arkh Patol 66:31-6. 2004
    ....
  42. ncbi request reprint Malignant peripheral primitive neuroectodermal tumor-peripheral neuroepithelioma of the head and neck: a clinicopathologic study of five cases and review of the literature
    Nikolaos G Nikitakis
    Department of Diagnostic Sciences and Pathology, Dental School, University of Maryland, Baltimore, 666 W Baltimore Street, Room 4 C 02, Baltimore, Maryland 21201 1586, USA
    Head Neck 25:488-98. 2003
    ..Here, we focus on one particular member of the PNET family, the malignant peripheral PNET (pPNET) or peripheral neuroepithelioma of head and neck...
  43. ncbi request reprint Splenic hamartoma: immunohistochemical and ultrastructural profile of two cases
    Tehmina Z Ali
    Department of Pathology, University of Maryland Medical Center, Baltimore, Maryland 21201, USA
    Int J Surg Pathol 13:103-11. 2005
    ..Our study highlights the unique immunohistochemical profile of SH. The ultrastructural features are interesting, although their diagnostic significance remains to be confirmed in future studies...
  44. ncbi request reprint MDM2 and CDK4 expression in carcinosarcoma of the esophagus: comparison with squamous cell carcinoma and review of the literature
    Nikolaos G Nikitakis
    Department of Diagnostic Sciences and Pathology, Dental School, University of Maryland, Baltimore, Maryland 21201 1586, USA
    Exp Mol Pathol 73:198-208. 2002
    ..These differences in the MDM2 and CDK4 immunohistochemical profile between carcinosarcomas and carcinomas of the esophagus may assist in their differential diagnosis...
  45. pmc Primary histiocytic sarcoma arising in the head and neck with predominant spindle cell component
    Borislav A Alexiev
    University of Maryland Medical Center, Department of Pathology, NBW43, 22 S Greene Street, Baltimore, MD 21201, USA
    Diagn Pathol 2:7. 2007
    ..Chromosome study revealed a 57-80 hyperdiploid [7]/46, XY [13] karyotype, including 3 to 4 copies of various chromosomes. The immunohistochemical and ultrastructural findings confirmed the diagnosis of HS...
  46. ncbi request reprint Sebaceous adenoma of the parotid gland in a 2-year-old male
    Kevin C Welch
    Department of Otorhinolaryngology, University of Maryland School of Medicine Baltimore, Baltimore, MD, USA
    Otolaryngol Head Neck Surg 136:672-3. 2007
  47. ncbi request reprint Primary Sjögren syndrome in childhood: report of a case and review of the literature
    Nikolaos G Nikitakis
    Department of Diagnostic Sciences and Pathology, University of Maryland, Baltimore 21201 1586, USA
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 96:42-7. 2003
    ..The salient features of this rare disease are summarized on the basis of a comprehensive review of the epidemiologic, clinical, and serologic findings of the previously reported cases of PSS in children...