Matthew S Panizzon

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc Distinct genetic influences on cortical surface area and cortical thickness
    Matthew S Panizzon
    Department of Psychiatry, University of California, San Diego, La Jolla, CA 92093, USA
    Cereb Cortex 19:2728-35. 2009
  2. pmc Genetic architecture of learning and delayed recall: a twin study of episodic memory
    Matthew S Panizzon
    Department of Psychiatry, University of California, San Diego, La Jolla, CA 92093, USA
    Neuropsychology 25:488-98. 2011
  3. ncbi request reprint Interaction of APOE genotype and testosterone on episodic memory in middle-aged men
    Matthew S Panizzon
    Department of Psychiatry, University of California, San Diego, CA, USA Twin Research Laboratory, Center for Behavioral Genomics, University of California, San Diego, CA, USA Electronic address
    Neurobiol Aging 35:1778.e1-8. 2014
  4. pmc Genetic and environmental influences of daily and intra-individual variation in testosterone levels in middle-aged men
    Matthew S Panizzon
    Department of Psychiatry, University of California, San Diego, La Jolla, CA, United States Twin Research Laboratory, Center for Behavioral Genomics, University of California, San Diego, La Jolla, CA, United States Electronic address
    Psychoneuroendocrinology 38:2163-72. 2013
  5. pmc Genetic and environmental influences of white and gray matter signal contrast: a new phenotype for imaging genetics?
    Matthew S Panizzon
    Department of Psychiatry, University of California, San Diego, La Jolla, CA 92093, USA
    Neuroimage 60:1686-95. 2012
  6. pmc Genetic influences on hippocampal volume differ as a function of testosterone level in middle-aged men
    Matthew S Panizzon
    Department of Psychiatry, University of California, San Diego, La Jolla, CA 92093, USA
    Neuroimage 59:1123-31. 2012
  7. pmc Testosterone modifies the effect of APOE genotype on hippocampal volume in middle-aged men
    M S Panizzon
    Department of Psychiatry, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 9293 0738, USA
    Neurology 75:874-80. 2010
  8. pmc Cross-sectional and 35-year longitudinal assessment of salivary cortisol and cognitive functioning: the Vietnam Era twin study of aging
    Carol E Franz
    University of California San Diego, Department of Psychiatry, 9500 Gilman Drive, MC0738, La Jolla, CA 92093, USA
    Psychoneuroendocrinology 36:1040-52. 2011
  9. ncbi request reprint Genetics of brain structure: contributions from the Vietnam Era Twin Study of Aging
    William S Kremen
    Department of Psychiatry, University of California, San Diego, La Jolla, California Twin Research Laboratory, Center for Behavioral Genomics, University of California, San Diego, La Jolla, California Center of Excellence for Stress and Mental Health, VA San Diego Healthcare System, La Jolla, California
    Am J Med Genet B Neuropsychiatr Genet 162:751-61. 2013
  10. pmc Cognitive reserve moderates the association between hippocampal volume and episodic memory in middle age
    Eero Vuoksimaa
    Department of Psychiatry, University of California San Diego, La Jolla, CA, USA
    Neuropsychologia 51:1124-31. 2013

Detail Information

Publications33

  1. pmc Distinct genetic influences on cortical surface area and cortical thickness
    Matthew S Panizzon
    Department of Psychiatry, University of California, San Diego, La Jolla, CA 92093, USA
    Cereb Cortex 19:2728-35. 2009
    ..We conclude that using volume in a genetically informative study, or as an endophenotype for a disorder, may confound the underlying genetic architecture of brain structure...
  2. pmc Genetic architecture of learning and delayed recall: a twin study of episodic memory
    Matthew S Panizzon
    Department of Psychiatry, University of California, San Diego, La Jolla, CA 92093, USA
    Neuropsychology 25:488-98. 2011
    ....
  3. ncbi request reprint Interaction of APOE genotype and testosterone on episodic memory in middle-aged men
    Matthew S Panizzon
    Department of Psychiatry, University of California, San Diego, CA, USA Twin Research Laboratory, Center for Behavioral Genomics, University of California, San Diego, CA, USA Electronic address
    Neurobiol Aging 35:1778.e1-8. 2014
    ..Results support the hypothesis that APOE-ε4 status increases susceptibility to other risk factors, such as low testosterone, which may ultimately contribute to cognitive decline or dementia. ..
  4. pmc Genetic and environmental influences of daily and intra-individual variation in testosterone levels in middle-aged men
    Matthew S Panizzon
    Department of Psychiatry, University of California, San Diego, La Jolla, CA, United States Twin Research Laboratory, Center for Behavioral Genomics, University of California, San Diego, La Jolla, CA, United States Electronic address
    Psychoneuroendocrinology 38:2163-72. 2013
    ..The aim of the present study was to determine the degree to which genetic and environmental factors contribute to individual differences in testosterone throughout the day in middle-aged men...
  5. pmc Genetic and environmental influences of white and gray matter signal contrast: a new phenotype for imaging genetics?
    Matthew S Panizzon
    Department of Psychiatry, University of California, San Diego, La Jolla, CA 92093, USA
    Neuroimage 60:1686-95. 2012
    ..The lack of significant genetic correlations with cortical thickness suggests that this measure potentially represents a unique source of genetic variance, one that has yet to be explored by the field of imaging genetics...
  6. pmc Genetic influences on hippocampal volume differ as a function of testosterone level in middle-aged men
    Matthew S Panizzon
    Department of Psychiatry, University of California, San Diego, La Jolla, CA 92093, USA
    Neuroimage 59:1123-31. 2012
    ..To the best of our knowledge, this is the first study to demonstrate that the heritability of a brain structure in adults may be modified by an endogenous biological factor...
  7. pmc Testosterone modifies the effect of APOE genotype on hippocampal volume in middle-aged men
    M S Panizzon
    Department of Psychiatry, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 9293 0738, USA
    Neurology 75:874-80. 2010
    ..The aim of the present study was to examine the potential interaction of testosterone and APOE genotype with respect to hippocampal volume in middle age...
  8. pmc Cross-sectional and 35-year longitudinal assessment of salivary cortisol and cognitive functioning: the Vietnam Era twin study of aging
    Carol E Franz
    University of California San Diego, Department of Psychiatry, 9500 Gilman Drive, MC0738, La Jolla, CA 92093, USA
    Psychoneuroendocrinology 36:1040-52. 2011
    ..The results also suggest that the direction of effect is complex...
  9. ncbi request reprint Genetics of brain structure: contributions from the Vietnam Era Twin Study of Aging
    William S Kremen
    Department of Psychiatry, University of California, San Diego, La Jolla, California Twin Research Laboratory, Center for Behavioral Genomics, University of California, San Diego, La Jolla, California Center of Excellence for Stress and Mental Health, VA San Diego Healthcare System, La Jolla, California
    Am J Med Genet B Neuropsychiatr Genet 162:751-61. 2013
    ..Examples supporting the validity of these conclusions are provided...
  10. pmc Cognitive reserve moderates the association between hippocampal volume and episodic memory in middle age
    Eero Vuoksimaa
    Department of Psychiatry, University of California San Diego, La Jolla, CA, USA
    Neuropsychologia 51:1124-31. 2013
    ..e., lower levels of cognitive reserve. Our results provide support for the hypothesis that cognitive reserve moderates the relationship between brain structure and cognition in middle age, well before the onset of dementia...
  11. pmc A comparison of heritability maps of cortical surface area and thickness and the influence of adjustment for whole brain measures: a magnetic resonance imaging twin study
    Lisa T Eyler
    Department of Psychiatry, University of California San Diego, La Jolla, CA, USA
    Twin Res Hum Genet 15:304-14. 2012
    ..Implications regarding brain phenotypes for future genetic association studies are discussed...
  12. ncbi request reprint Adult cognitive ability and socioeconomic status as mediators of the effects of childhood disadvantage on salivary cortisol in aging adults
    Carol E Franz
    University of California San Diego, Department of Psychiatry, MC0738, La Jolla, CA 92093, USA Electronic address
    Psychoneuroendocrinology 38:2127-39. 2013
    ..8% of the total effect of childhood disadvantage [β=0.12 (0.05; 0.18)] on total daytime cortisol. Associations remained significant after accounting for ethnicity, smoking status, and self-reported depressive symptoms. ..
  13. pmc Presence of ApoE ε4 allele associated with thinner frontal cortex in middle age
    Christine Fennema-Notestine
    Department of Psychiatry, University of California, San Diego, La Jolla, CA 92093 0738, USA
    J Alzheimers Dis 26:49-60. 2011
    ..Ongoing follow-up of the VETSA sample may shed light on the potential for age- and disease-related mediation of the influence of ApoE allele status...
  14. pmc Genetic architecture of context processing in late middle age: more than one underlying mechanism
    William S Kremen
    Department of Psychiatry, Center for Behavioral Genomics, University of California, San Diego, USA
    Psychol Aging 26:852-63. 2011
    ..In contrast, the reactive control component was unrelated to general cognitive ability...
  15. pmc Genetic and environmental influences on the size of specific brain regions in midlife: the VETSA MRI study
    William S Kremen
    Department of Psychiatry, University of California, San Diego, 9500 Gilman Drive MC 0738, La Jolla, CA 92093, USA
    Neuroimage 49:1213-23. 2010
    ..Longitudinal analysis will be needed to determine whether the degree of genetic and environmental influences changes for different ROIs from midlife to later life...
  16. pmc Adult romantic attachment, negative emotionality, and depressive symptoms in middle aged men: a multivariate genetic analysis
    Carol E Franz
    Department of Psychiatry, University of California San Diego, La Jolla, CA 92093 0738, USA
    Behav Genet 41:488-98. 2011
    ..41, indicating some, but not complete overlap of genetic factors. Genetically informative longitudinal studies on attachment relationship dimensions can help to illuminate the role of relationship-based risk factors in healthy aging...
  17. pmc Factor structure of planning and problem-solving: a behavioral genetic analysis of the Tower of London task in middle-aged twins
    William S Kremen
    Department of Psychiatry, Center for Behavioral Genomics, University of California, San Diego, La Jolla, CA 92093 0738, USA
    Behav Genet 39:133-44. 2009
    ..The different phenotypic and genetic factor results suggest that relying solely on the former could obscure genetic associations...
  18. pmc Genetic influences on cortical regionalization in the human brain
    Chi Hua Chen
    Department of Psychiatry, University of California San Diego, La Jolla, CA 92093, USA
    Neuron 72:537-44. 2011
    ..Broad similarities in genetic patterning between rodents and humans might suggest a conservation of cortical patterning mechanisms, whereas dissimilarities might reflect the functionalities most essential to each species...
  19. pmc Hierarchical genetic organization of human cortical surface area
    Chi Hua Chen
    Department of Psychiatry, University of California, San Diego, La Jolla, CA 92093, USA
    Science 335:1634-6. 2012
    ..We also found that the results were consistent with human-specific regions being subdivisions of previously described, genetically based lobar regionalization patterns...
  20. pmc Heritability of brain ventricle volume: converging evidence from inconsistent results
    William S Kremen
    Department of Psychiatry, University of California, San Diego, La Jolla, CA 92093, USA
    Neurobiol Aging 33:1-8. 2012
    ..These conclusions have implications for the basic understanding of the genetic and environmental underpinnings of normative and pathological brain aging...
  21. pmc A twin study of spatial and non-spatial delayed response performance in middle age
    William S Kremen
    Department of Psychiatry, Center for Behavioral Genomics, University of California, San Diego, La Jolla, CA 92093 0738, USA
    Brain Cogn 76:43-51. 2011
    ..Compared with findings from small, selected control samples, high "failure" rates in this community-based sample raise concerns about interpretation of brain dysfunction in elderly or patient samples...
  22. pmc Genetic and environmental contributions to regional cortical surface area in humans: a magnetic resonance imaging twin study
    Lisa T Eyler
    Department of Psychiatry, University of California, San Diego, La Jolla, CA 92093, USA
    Cereb Cortex 21:2313-21. 2011
    ....
  23. ncbi request reprint Salivary cortisol and prefrontal cortical thickness in middle-aged men: A twin study
    William S Kremen
    Department of Psychiatry, University of California, San Diego, La Jolla, CA 92093, USA
    Neuroimage 53:1093-102. 2010
    ..Longitudinal assessments are underway to elucidate the direction of the associations and the genetic underpinnings of longitudinal phenotypes for changes in cortisol and brain morphology...
  24. pmc Genetic patterns of correlation among subcortical volumes in humans: results from a magnetic resonance imaging twin study
    Lisa T Eyler
    Department of Psychiatry, University of California, San Diego, La Jolla, California, USA
    Hum Brain Mapp 32:641-53. 2011
    ....
  25. pmc A 35-year longitudinal assessment of cognition and midlife depression symptoms: the Vietnam Era Twin Study of Aging
    Carol E Franz
    Department of Psychiatry, University of California, San Diego, 92093, USA
    Am J Geriatr Psychiatry 19:559-70. 2011
    ....
  26. ncbi request reprint Early identification and heritability of mild cognitive impairment
    William S Kremen
    Department of Psychiatry, University of California, San Diego, La Jolla, CA, USA, Center of Excellence for Stress and Mental Health, VA San Diego Healthcare System, La Jolla, CA, USA, Psychology Service, VA San Diego Healthcare System, La Jolla, CA, USA, Computational Science Research Center, San Diego State University Claremont Graduate University, San Diego, CA, USA, Department of Psychiatry and Behavioral Neuroscience, University of Chicago, Chicago, IL, USA, Department of Public Health, University of Helsinki, Helsinki, Finland, Department of Statistics, St Louis University, St Louis, MO, USA, Research Service, VA St Louis Healthcare System, St Louis, MO, USA and Department of Psychology, Boston University, Boston, MA, USA
    Int J Epidemiol 43:600-10. 2014
    ..We estimated prevalence rates, association with premorbid general cognitive ability (GCA) and heritability for different definitions of neuropsychologically defined MCI in adults in their 50s...
  27. ncbi request reprint Conceptual and Data-based Investigation of Genetic Influences and Brain Asymmetry: A Twin Study of Multiple Structural Phenotypes
    Lisa T Eyler
    University of California, San Diego
    J Cogn Neurosci 26:1100-17. 2014
    ..Despite varying interpretations of existing data, we view the present results as consistent with previous findings. ..
  28. pmc Storage and executive components of working memory: integrating cognitive psychology and behavior genetics in the study of aging
    William S Kremen
    Department of Psychiatry, Center for Behavioral Genomics, University of California San Diego, 9500 Gilman Drive, La Jolla, CA, USA
    J Gerontol B Psychol Sci Soc Sci 63:P84-91. 2008
    ..We discuss the findings in the context of research suggesting that new genetic influences come into play if demand continues to increase beyond a certain threshold, a threshold that may change with task difficulty and with age...
  29. pmc Cortical thickness is influenced by regionally specific genetic factors
    Lars M Rimol
    Department of Radiology, University of California, San Diego, La Jolla, California 92093 0738, USA
    Biol Psychiatry 67:493-9. 2010
    ..Yet, little is known about the patterning of those genetic influences, i.e., whether the same genes influence structure throughout the brain or whether there are regionally specific sets of genes...
  30. ncbi request reprint Genetic complexity of episodic memory: A twin approach to studies of aging
    William S Kremen
    Department of Psychiatry, Center for Behavioral Genomics
    Psychol Aging 29:404-17. 2014
    ..This approach represents an important step toward providing critical information for all types of genetically informative studies of aging and memory. (PsycINFO Database Record (c) 2014 APA, all rights reserved). ..
  31. ncbi request reprint Imputing observed blood pressure for antihypertensive treatment: impact on population and genetic analyses
    Brinda K Rana
    Department of Psychiatry, University of California San Diego, La Jolla, California, USA
    Am J Hypertens 27:828-37. 2014
    ..Routine methods to adjust for antihypertensives may not sufficiently account for newer treatment protocols (i.e., combination or multiple drug therapy) found in contemporary cohorts...
  32. pmc Genetic topography of brain morphology
    Chi Hua Chen
    Departments of Psychiatry, Cognitive Science, Radiology, and Neurosciences, Center for Behavioral Genomics, and Institute of Genomic Medicine, University of California, San Diego, La Jolla, CA 92093
    Proc Natl Acad Sci U S A 110:17089-94. 2013
    ..Our findings highlight the complexity of genetic influences on cortical morphology and provide a glimpse into emerging principles of genetic organization of the cortex. ..
  33. ncbi request reprint Genetic and environmental multidimensionality of well- and ill-being in middle aged twin men
    Carol E Franz
    Department of Psychiatry, University of California San Diego, MC0738, La Jolla, CA 92093, USA
    Behav Genet 42:579-91. 2012
    ..All measures had specific unique environmental influences. Results indicate that well-being is genetically and environmentally multidimensional and that ill-being has partial overlap with both latent factors...