Jinjiang Pang

Summary

Affiliation: University of Rochester
Country: USA

Publications

  1. pmc G-protein-coupled receptor kinase interacting protein-1 mediates intima formation by regulating vascular smooth muscle proliferation, apoptosis, and migration
    Jinjiang Pang
    Aab Cardiovascular Research Institute, University of Rochester, Box CVRI, 601 Elmwood Ave, Rochester, NY 14642, USA
    Arterioscler Thromb Vasc Biol 33:999-1005. 2013
  2. pmc G protein coupled receptor kinase 2 interacting protein 1 (GIT1) is a novel regulator of mitochondrial biogenesis in heart
    Jinjiang Pang
    Aab Cardiovascular Research Institute, Rochester, NY 14642, USA
    J Mol Cell Cardiol 51:769-76. 2011
  3. pmc Thioredoxin-interacting protein mediates sustained VEGFR2 signaling in endothelial cells required for angiogenesis
    Shin Young Park
    Aab Cardiovascular Research Institute, University of Rochester, 601 Elmwood Ave, Box CVRI, Rochester, NY 14642, USA
    Arterioscler Thromb Vasc Biol 33:737-43. 2013
  4. pmc G-protein-coupled receptor kinase interacting protein-1 is required for pulmonary vascular development
    Jinjiang Pang
    Aab Cardiovascular Research Institute and the Department of Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    Circulation 119:1524-32. 2009
  5. pmc Phosphorylation of G protein-coupled receptor kinase 2-interacting protein 1 tyrosine 392 is required for phospholipase C-gamma activation and podosome formation in vascular smooth muscle cells
    Jing Wang
    Aab Cardiovascular Research Institute and Department of Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    Arterioscler Thromb Vasc Biol 30:1976-82. 2010
  6. pmc GIT1 mediates VEGF-induced podosome formation in endothelial cells: critical role for PLCgamma
    Jing Wang
    Aab Cardiovascular Research Institute, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    Arterioscler Thromb Vasc Biol 29:202-8. 2009
  7. pmc An epidermal growth factor (EGF) -dependent interaction between GIT1 and sorting nexin 6 promotes degradation of the EGF receptor
    Megan E Cavet
    Aab Cardiovascular Research Institute and Department of Medicine, University of Rochester School of Medicine, Rochester, New York 14642, USA
    FASEB J 22:3607-16. 2008
  8. pmc EVI1 acts as an inducible negative-feedback regulator of NF-κB by inhibiting p65 acetylation
    Xiangbin Xu
    Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, NY 14642, USA
    J Immunol 188:6371-80. 2012
  9. pmc Phospholipase Cε hydrolyzes perinuclear phosphatidylinositol 4-phosphate to regulate cardiac hypertrophy
    Lianghui Zhang
    Department of Pharmacology and Physiology, University of Rochester School of Medicine and Dentistry, 601 Elmwood Avenue, Rochester, NY 14642, USA
    Cell 153:216-27. 2013
  10. pmc GIT1 mediates HDAC5 activation by angiotensin II in vascular smooth muscle cells
    Jinjiang Pang
    Aab Cardiovascular Research Institute and the Department of Medicine, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, USA
    Arterioscler Thromb Vasc Biol 28:892-8. 2008

Collaborators

Detail Information

Publications10

  1. pmc G-protein-coupled receptor kinase interacting protein-1 mediates intima formation by regulating vascular smooth muscle proliferation, apoptosis, and migration
    Jinjiang Pang
    Aab Cardiovascular Research Institute, University of Rochester, Box CVRI, 601 Elmwood Ave, Rochester, NY 14642, USA
    Arterioscler Thromb Vasc Biol 33:999-1005. 2013
    ..Because GIT1 regulates signaling by several vascular smooth muscle cell (VSMC) growth factors, we hypothesized that intima formation would be inhibited by GIT1 depletion...
  2. pmc G protein coupled receptor kinase 2 interacting protein 1 (GIT1) is a novel regulator of mitochondrial biogenesis in heart
    Jinjiang Pang
    Aab Cardiovascular Research Institute, Rochester, NY 14642, USA
    J Mol Cell Cardiol 51:769-76. 2011
    ..In conclusion, our findings identify GIT1 as a new regulator of mitochondrial biogenesis and function, which is necessary for postnatal cardiac maturation...
  3. pmc Thioredoxin-interacting protein mediates sustained VEGFR2 signaling in endothelial cells required for angiogenesis
    Shin Young Park
    Aab Cardiovascular Research Institute, University of Rochester, 601 Elmwood Ave, Box CVRI, Rochester, NY 14642, USA
    Arterioscler Thromb Vasc Biol 33:737-43. 2013
    ..Because VEGFR2 is critical for angiogenesis, we explored the role of TXNIP in VEGF-induced angiogenesis...
  4. pmc G-protein-coupled receptor kinase interacting protein-1 is required for pulmonary vascular development
    Jinjiang Pang
    Aab Cardiovascular Research Institute and the Department of Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    Circulation 119:1524-32. 2009
    ..However, there have been no in vivo studies of GIT1 function to date...
  5. pmc Phosphorylation of G protein-coupled receptor kinase 2-interacting protein 1 tyrosine 392 is required for phospholipase C-gamma activation and podosome formation in vascular smooth muscle cells
    Jing Wang
    Aab Cardiovascular Research Institute and Department of Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    Arterioscler Thromb Vasc Biol 30:1976-82. 2010
    ..In this study, we identified specific GIT1 tyrosines required for PLCγ activation and podosome formation in vascular smooth muscle cells (VSMC)...
  6. pmc GIT1 mediates VEGF-induced podosome formation in endothelial cells: critical role for PLCgamma
    Jing Wang
    Aab Cardiovascular Research Institute, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    Arterioscler Thromb Vasc Biol 29:202-8. 2009
    ..Because GIT1 is a substrate of c-Src, and podosome formation is c-Src dependent, we hypothesized that GIT1 plays an important role in VEGF-induced EC podosome formation and cell migration...
  7. pmc An epidermal growth factor (EGF) -dependent interaction between GIT1 and sorting nexin 6 promotes degradation of the EGF receptor
    Megan E Cavet
    Aab Cardiovascular Research Institute and Department of Medicine, University of Rochester School of Medicine, Rochester, New York 14642, USA
    FASEB J 22:3607-16. 2008
    ..Our findings suggest a new role for GIT1 in tyrosine kinase receptor trafficking...
  8. pmc EVI1 acts as an inducible negative-feedback regulator of NF-κB by inhibiting p65 acetylation
    Xiangbin Xu
    Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, NY 14642, USA
    J Immunol 188:6371-80. 2012
    ..Thus, our study provides important insights into the novel role for EVI1 in negatively regulating NF-κB-dependent inflammation, and it may also shed light on the future development of novel anti-inflammatory strategies...
  9. pmc Phospholipase Cε hydrolyzes perinuclear phosphatidylinositol 4-phosphate to regulate cardiac hypertrophy
    Lianghui Zhang
    Department of Pharmacology and Physiology, University of Rochester School of Medicine and Dentistry, 601 Elmwood Avenue, Rochester, NY 14642, USA
    Cell 153:216-27. 2013
    ....
  10. pmc GIT1 mediates HDAC5 activation by angiotensin II in vascular smooth muscle cells
    Jinjiang Pang
    Aab Cardiovascular Research Institute and the Department of Medicine, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, USA
    Arterioscler Thromb Vasc Biol 28:892-8. 2008
    ..Here we investigated the hypothesis that Ang II-mediated vascular smooth muscle cell (VSMC) gene transcription involves GIT1-CamK II-dependent phosphorylation of HDAC5...