Gladell P Paner

Summary

Affiliation: University of Chicago
Country: USA

Publications

  1. doi request reprint Primary thyroid-like follicular carcinoma of the kidney: report of 6 cases of a histologically distinctive adult renal epithelial neoplasm
    Mahul B Amin
    Department of Pathology, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    Am J Surg Pathol 33:393-400. 2009
  2. doi request reprint Urachal carcinomas of the nonglandular type: salient features and considerations in pathologic diagnosis
    Gladell P Paner
    Department of Pathology, University of Chicago, Chicago, IL 60637, USA
    Am J Surg Pathol 36:432-42. 2012
  3. doi request reprint Immunohistochemical analysis in a morphologic spectrum of urachal epithelial neoplasms: diagnostic implications and pitfalls
    Gladell P Paner
    Department of Pathology, University of Chicago, 5841 S Maryland Avenue, Chicago, IL 60637, USA
    Am J Surg Pathol 35:787-98. 2011
  4. doi request reprint Urothelial neoplasms of the urinary bladder occurring in young adult and pediatric patients: a comprehensive review of literature with implications for patient management
    Gladell P Paner
    Department of Pathology, Section of Urology, The University of Chicago Hospitals, 5841 S Maryland Avenue, Chicago, IL 60637, USA
    Adv Anat Pathol 18:79-89. 2011
  5. pmc Predictors of Gleason Score (GS) upgrading on subsequent prostatectomy: a single Institution study in a cohort of patients with GS 6
    Vikas Mehta
    Department of Pathology, Loyola University Medical Center, Maywood, IL 60153, USA
    Int J Clin Exp Pathol 5:496-502. 2012
  6. ncbi request reprint Expression analysis of kidney-specific cadherin in a wide spectrum of traditional and newly recognized renal epithelial neoplasms: diagnostic and histogenetic implications
    Adam Kuehn
    Department of Pathology, Emory University Hospital, Atlanta, GA, USA
    Am J Surg Pathol 31:1528-33. 2007
  7. doi request reprint Morphometric signature differences in nuclei of Gleason pattern 4 areas in Gleason 7 prostate cancer with differing primary grades on needle biopsy
    Girish Venkataraman
    Department of Pathology, Loyola University Medical Center, Maywood, Illinois, USA
    J Urol 181:88-93; discussion 93-4. 2009
  8. ncbi request reprint Identification of patients with low-risk for aneuploidy: comparative discriminatory models using linear and machine-learning classifiers in prostate cancer
    Girish Venkataraman
    Department of Pathology, Loyola University Medical Center, Maywood, Illinois 60153, USA
    Prostate 67:1524-36. 2007
  9. doi request reprint Influence of Histologic Criteria and Confounding Factors in Staging Equivocal Cases for Microscopic Perivesical Tissue Invasion (pT3a): An Interobserver Study Among Genitourinary Pathologists
    Vijayalakshmi Ananthanarayanan
    Department of Pathology, University of Chicago, Chicago, IL Department of Biostatistics and Bioinformatics, Rollins School of Public Health Department of Pathology and Laboratory Medicine, Emory University, Atlanta, GA Pathology and Laboratory Medicine, Cedars Sinai Medical Center, Los Angeles, CA Department of Pathology and Laboratory Medicine, Indiana University, Indianapolis, IN Department of Pathology, Johns Hopkins Hospital, Baltimore, MD Department of Pathology, University of California, San Diego, CA Division of Anatomic Pathology, Mayo Clinic, Rochester, MN Department of Anatomic Pathology, Cleveland Clinic, Cleveland, OH Department of Pathology, Massachusetts General Hospital, Boston, MA Department of Pathology, MD Anderson Cancer Center Department of Pathology, Methodist Hospital, Houston, TX Department of Pathology, Memorial Sloan Kettering Cancer Center, New York Department of Pathology, University of Rochester Medical Center, Rochester, NY Section of Pathological Anatomy, Polytechnic University of the Marche Region, Ancona, Italy Department of Pathology and Molecular Medicine, McMaster University, Hamilton, ON, Canada Department of Pathology, Nagoya Daini Red Cross Hospital, Nagoya
    Am J Surg Pathol 38:167-75. 2014
  10. doi request reprint Diagnostic utility of antibody to smoothelin in the distinction of muscularis propria from muscularis mucosae of the urinary bladder: a potential ancillary tool in the pathologic staging of invasive urothelial carcinoma
    Gladell P Paner
    Department of Pathology, Urology, Loyola University Medical Center, Maywood, IL, USA
    Am J Surg Pathol 33:91-8. 2009

Detail Information

Publications31

  1. doi request reprint Primary thyroid-like follicular carcinoma of the kidney: report of 6 cases of a histologically distinctive adult renal epithelial neoplasm
    Mahul B Amin
    Department of Pathology, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    Am J Surg Pathol 33:393-400. 2009
    ..Thyroid-like follicular renal cell carcinoma represents a unique histologic subtype of renal cell carcinoma of low malignant potential and its primary importance is to distinguish it from metastatic carcinoma from the thyroid...
  2. doi request reprint Urachal carcinomas of the nonglandular type: salient features and considerations in pathologic diagnosis
    Gladell P Paner
    Department of Pathology, University of Chicago, Chicago, IL 60637, USA
    Am J Surg Pathol 36:432-42. 2012
    ..Concomitant primary urothelial carcinoma outside of the urachus and tumor extension to bladder mucosa may occur, which should not negate diagnosis of an urachal primary. Behavior appears poor, as most tumors present with higher stage...
  3. doi request reprint Immunohistochemical analysis in a morphologic spectrum of urachal epithelial neoplasms: diagnostic implications and pitfalls
    Gladell P Paner
    Department of Pathology, University of Chicago, 5841 S Maryland Avenue, Chicago, IL 60637, USA
    Am J Surg Pathol 35:787-98. 2011
    ..Knowledge of the similarity in immunostaining to its different morphologic mimics may help avoid misdiagnosis in urachal adenocarcinoma...
  4. doi request reprint Urothelial neoplasms of the urinary bladder occurring in young adult and pediatric patients: a comprehensive review of literature with implications for patient management
    Gladell P Paner
    Department of Pathology, Section of Urology, The University of Chicago Hospitals, 5841 S Maryland Avenue, Chicago, IL 60637, USA
    Adv Anat Pathol 18:79-89. 2011
    ....
  5. pmc Predictors of Gleason Score (GS) upgrading on subsequent prostatectomy: a single Institution study in a cohort of patients with GS 6
    Vikas Mehta
    Department of Pathology, Loyola University Medical Center, Maywood, IL 60153, USA
    Int J Clin Exp Pathol 5:496-502. 2012
    ..3), upgrading of a bGS of 6 to a GS≥7 has serious implications. We sought to identify pre-operative factors associated with upgrading in a cohort of GS6 patients who underwent prostatectomy...
  6. ncbi request reprint Expression analysis of kidney-specific cadherin in a wide spectrum of traditional and newly recognized renal epithelial neoplasms: diagnostic and histogenetic implications
    Adam Kuehn
    Department of Pathology, Emory University Hospital, Atlanta, GA, USA
    Am J Surg Pathol 31:1528-33. 2007
    ....
  7. doi request reprint Morphometric signature differences in nuclei of Gleason pattern 4 areas in Gleason 7 prostate cancer with differing primary grades on needle biopsy
    Girish Venkataraman
    Department of Pathology, Loyola University Medical Center, Maywood, Illinois, USA
    J Urol 181:88-93; discussion 93-4. 2009
    ..Since clinically significant upgrading of the biopsy Gleason score has an adverse clinical impact, ancillary tools besides the visual determination of primary Gleason pattern are essential to aid in better risk stratification...
  8. ncbi request reprint Identification of patients with low-risk for aneuploidy: comparative discriminatory models using linear and machine-learning classifiers in prostate cancer
    Girish Venkataraman
    Department of Pathology, Loyola University Medical Center, Maywood, Illinois 60153, USA
    Prostate 67:1524-36. 2007
    ..Prostate needle biopsy (PNB) ploidy status has proven utility to predict adverse outcomes after prostatectomy. We sought to develop models to predict ploidy status using clinicopathologic variables...
  9. doi request reprint Influence of Histologic Criteria and Confounding Factors in Staging Equivocal Cases for Microscopic Perivesical Tissue Invasion (pT3a): An Interobserver Study Among Genitourinary Pathologists
    Vijayalakshmi Ananthanarayanan
    Department of Pathology, University of Chicago, Chicago, IL Department of Biostatistics and Bioinformatics, Rollins School of Public Health Department of Pathology and Laboratory Medicine, Emory University, Atlanta, GA Pathology and Laboratory Medicine, Cedars Sinai Medical Center, Los Angeles, CA Department of Pathology and Laboratory Medicine, Indiana University, Indianapolis, IN Department of Pathology, Johns Hopkins Hospital, Baltimore, MD Department of Pathology, University of California, San Diego, CA Division of Anatomic Pathology, Mayo Clinic, Rochester, MN Department of Anatomic Pathology, Cleveland Clinic, Cleveland, OH Department of Pathology, Massachusetts General Hospital, Boston, MA Department of Pathology, MD Anderson Cancer Center Department of Pathology, Methodist Hospital, Houston, TX Department of Pathology, Memorial Sloan Kettering Cancer Center, New York Department of Pathology, University of Rochester Medical Center, Rochester, NY Section of Pathological Anatomy, Polytechnic University of the Marche Region, Ancona, Italy Department of Pathology and Molecular Medicine, McMaster University, Hamilton, ON, Canada Department of Pathology, Nagoya Daini Red Cross Hospital, Nagoya
    Am J Surg Pathol 38:167-75. 2014
    ..This study highlights the need to adopt common criteria in defining the outer MP boundary. Future studies may identify the most clinically relevant histoanatomic criteria for MPVTI. ..
  10. doi request reprint Diagnostic utility of antibody to smoothelin in the distinction of muscularis propria from muscularis mucosae of the urinary bladder: a potential ancillary tool in the pathologic staging of invasive urothelial carcinoma
    Gladell P Paner
    Department of Pathology, Urology, Loyola University Medical Center, Maywood, IL, USA
    Am J Surg Pathol 33:91-8. 2009
    ....
  11. doi request reprint A novel tumor grading scheme for chromophobe renal cell carcinoma: prognostic utility and comparison with Fuhrman nuclear grade
    Gladell P Paner
    Department of Pathology, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    Am J Surg Pathol 34:1233-40. 2010
    ....
  12. ncbi request reprint High incidence of chromosome 1 abnormalities in a series of 27 renal oncocytomas: cytogenetic and fluorescence in situ hybridization studies
    Gladell P Paner
    Department of Pathology, Loyola University Medical Center, Maywood, Ill 60153, USA
    Arch Pathol Lab Med 131:81-5. 2007
    ..It has recently been shown by cytogenetics that there is a high incidence of chromosome 1 abnormalities in renal oncocytomas...
  13. doi request reprint Tubulocystic carcinoma of the kidney: clinicopathologic analysis of 31 cases of a distinctive rare subtype of renal cell carcinoma
    Mahul B Amin
    Department of Pathology, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    Am J Surg Pathol 33:384-92. 2009
    ..In light of the distinctive clinicopathologic features and a low but definite metastatic potential, this unique subtype of renal cell carcinoma deserves formal recognition in the contemporary classification of renal neoplasms...
  14. doi request reprint The different morphologies of urachal adenocarcinoma do not discriminate genomically by micro-RNA expression profiling
    Mei Lin Z Bissonnette
    Department of Pathology, University of Chicago, Chicago, IL 60637, USA
    Hum Pathol 44:1605-11. 2013
    ..This finding, if further validated in larger studies, may have implications in future clinical therapeutic trials for urachal adenocarcinoma with regard to patient grouping and choice of therapy. ..
  15. doi request reprint Validation of new AJCC exclusion criteria for subepithelial prostatic stromal invasion from pT4a bladder urothelial carcinoma
    Amit R Patel
    Section of Urology, University of Chicago, Chicago, Illinois, USA
    J Urol 189:53-8. 2013
    ..We determined if the new guidelines were reflective of differences in survival between subepithelial prostatic stromal invasion and transmural pT4a disease...
  16. pmc Deregulation of a Hox protein regulatory network spanning prostate cancer initiation and progression
    James L Chen
    Department of Medicine, The University of Chicago, Chicago, IL, USA
    Clin Cancer Res 18:4291-302. 2012
    ..To this end, despite shared androgen-dependence and functional similarities to the prostate gland, seminal vesicle cancer is exceptionally rare...
  17. ncbi request reprint Immunohistochemical analysis of mucinous tubular and spindle cell carcinoma and papillary renal cell carcinoma of the kidney: significant immunophenotypic overlap warrants diagnostic caution
    Gladell P Paner
    Department of Pathology, Emory University Hospital, 1364 Clifton Road NE, G 167, Atlanta, GA 30322, USA
    Am J Surg Pathol 30:13-9. 2006
    ....
  18. doi request reprint Renal cell carcinoma: assessment of key pathologic prognostic parameters and patient characteristics in 47,909 cases using the National Cancer Data Base
    Nalan Nese
    Department of Pathology, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    Ann Diagn Pathol 13:1-8. 2009
    ....
  19. doi request reprint Interobserver reproducibility in the diagnosis of invasive micropapillary carcinoma of the urinary tract among urologic pathologists
    Ankur R Sangoi
    Department of Pathology, Stanford University, Stanford, CA, USA
    Am J Surg Pathol 34:1367-76. 2010
    ..These findings suggest that more study of IMPC is needed to identify the individual pathologic features that might potentially correlate with an aggressive outcome and response to intravesical therapy...
  20. doi request reprint Primary vascular tumors and tumor-like lesions of the kidney: a clinicopathologic analysis of 25 cases
    Jeffrey G Brown
    Department of Pathology, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    Am J Surg Pathol 34:942-9. 2010
    ....
  21. doi request reprint Diagnostic implications of transcription factor Pax 2 protein and transmembrane enzyme complex carbonic anhydrase IX immunoreactivity in adult renal epithelial neoplasms
    Ruta Gupta
    Department of Pathology, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    Am J Surg Pathol 33:241-7. 2009
    ..These antibodies may reliably discriminate between clinically significant subtypes of RCC with overlapping cytoarchitectural features...
  22. pmc Aire-dependent thymic development of tumor-associated regulatory T cells
    Sven Malchow
    Department of Pathology, University of Chicago, Chicago, IL 60637, USA
    Science 339:1219-24. 2013
    ..Thus, Aire-mediated expression of peripheral tissue antigens drives the thymic development of a subset of organ-specific T(regs), which are likely coopted by tumors developing within the associated organ...
  23. ncbi request reprint Passive seeding in metanephric adenoma: a review of pseudometastatic lesions in perinephric lymph nodes
    Gladell P Paner
    Department of Pathology, Loyola University Medical Center, Maywood, IL 60153, USA
    Arch Pathol Lab Med 129:1317-21. 2005
    ..We conclude that this phenomenon is understudied and underrecognized and can easily be mistaken for metastasis...
  24. ncbi request reprint Morphometric sum optical density as a surrogate marker for ploidy status in prostate cancer: an analysis in 180 biopsies using logistic regression and binary recursive partitioning
    Girish Venkataraman
    Department of Pathology, Loyola University Medical Center, 2160, South First Avenue, Bldg 110, Room 2233, Maywood, IL 60153, USA
    Virchows Arch 449:302-7. 2006
    ..Morphometric OD can be used as a surrogate marker of nondiploidy. LR and BRP models are both equivalent in identifying and correctly classifying nondiploid cases of prostate cancer using sum OD as the predictor variable...
  25. doi request reprint Is GATA3 expression maintained in regional metastases?: a study of paired primary and metastatic urothelial carcinomas
    Lei Zhao
    Department of Pathology, University of Chicago, Chicago, IL Departments of Biostatistics Pathology, University of Washington, Seattle, WA
    Am J Surg Pathol 37:1876-81. 2013
    ..Our findings demonstrate high sensitivity and specificity of the GATA3 diagnostic marker, with not only maintained but increased expression in regional metastases. ..
  26. doi request reprint Non-epithelial neoplasms of the prostate
    Gladell P Paner
    Department of Pathology, University of Chicago, Chicago, IL, USA
    Histopathology 60:166-86. 2012
    ..This review addresses and updates the clinicopathological features of the entire spectrum of non-epithelial tumours with an approach to the histological diagnosis...
  27. pmc Fyn is downstream of the HGF/MET signaling axis and affects cellular shape and tropism in PC3 cells
    Ana R Jensen
    Section of Hematology Oncology, Department of Medicine, Section of Urology, University of Chicago, Chicago, Illinois, USA
    Clin Cancer Res 17:3112-22. 2011
    ..Fyn is a member of the Src family of kinases that we have previously shown to be overexpressed in prostate cancer. This study defines the biological impact of Fyn inhibition in cancer using a PC3 prostate cancer model...
  28. ncbi request reprint Renal neoplasms in younger adults: analysis of 112 tumors from a single institution according to the new 2004 World Health Organization classification and 2002 American Joint Committee on Cancer Staging System
    Ying Cao
    Department of Pathology, Loyola University Chicago Medical Center, Maywood, Ill 60153, USA
    Arch Pathol Lab Med 129:487-91. 2005
    ..Recent modification of the World Health Organization histologic classification and the American Joint Committee on Cancer staging system of adult renal tumors further highlighted the need for case analysis in this age group...
  29. ncbi request reprint Sentinel node status and tumor characteristics: a study of 234 invasive breast carcinomas
    Ying Cao
    Department of Pathology, Loyola University Chicago Medical Center, Maywood, IL 60153, USA
    Arch Pathol Lab Med 129:82-4. 2005
    ..With the advent of lymphatic mapping and sentinel node (SN) identification, there is potential for a more efficient and sensitive evaluation of the axillary lymph node status...
  30. doi request reprint Rete testis-associated nodular steroid cell nests: description of putative pluripotential testicular hilus steroid cells
    Gladell P Paner
    Department of Pathology, University of Chicago, Chicago, IL, USA
    Am J Surg Pathol 35:505-11. 2011
    ..We propose to name these proliferations rete testis-associated nodular steroid cell nests...
  31. doi request reprint Clinicopathologic analysis of choriocarcinoma as a pure or predominant component of germ cell tumor of the testis
    Isabel Alvarado-Cabrero
    Departments of Pathology Urology, Mexican Oncology Hospital, IMSS, Mexico City, Mexico Departments of Pathology and Surgery, Section of Urology, University of Chicago, Chicago, IL
    Am J Surg Pathol 38:111-8. 2014
    ..The mononucleated trophoblastic columns in testicular CC appear to be a mixture of cytotrophoblasts and intermediate trophoblasts, similar to that described in gestational CC. ..