TEJ PANDITA

Summary

Affiliation: University of Texas Southwestern Medical Center
Country: USA

Publications

  1. pmc Chromatin modifications and the DNA damage response to ionizing radiation
    Rakesh Kumar
    Department of Radiation Oncology, University of Texas Southwestern Medical Center Dallas, TX, USA
    Front Oncol 2:214. 2012
  2. ncbi request reprint The role of inflammatory pathways in cancer-associated cachexia and radiation resistance
    Aaron Laine
    University of Texas Southwestern Medical Center, Department of Radiation Oncology, 5801 Forest Park Road, Dallas, TX 75235
    Mol Cancer Res 11:967-72. 2013
  3. pmc Genome-wide distribution of histone H4 Lysine 16 acetylation sites and their relationship to gene expression
    Nobuo Horikoshi
    Department of Radiation Oncology, Division of Molecular Radiation Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
    Genome Integr 4:3. 2013
  4. doi request reprint Histone H4 lysine 16 acetylated isoform synthesis opens new route to biophysical studies
    Tej K Pandita
    Department of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
    Proteomics 13:1546-7. 2013
  5. doi request reprint 14th International Workshop on Ataxia-Telangiectasia ATW2012
    Tej K Pandita
    Department of Radiation Oncology, University of Texas South Western Medical Center, Dallas, TX 75390, USA Electronic address
    DNA Repair (Amst) 11:853-6. 2012
  6. pmc Tip60-mediated acetylation activates transcription independent apoptotic activity of Abl
    Zhihua Jiang
    Department of Microbiology and Molecular Genetics, Pittsburgh, PA 15240, USA
    Mol Cancer 10:88. 2011

Collaborators

  • Hari S Misra
  • Rakesh Kumar
  • Aaron Laine
  • Nobuo Horikoshi
  • Zhihua Jiang
  • Pankaj Kumar
  • Shantanu Chowdhury
  • Girdhar G Sharma
  • Puneeth Iyengar
  • Kenneth Westover
  • Min Chen
  • Clayton R Hunt
  • Manimalha Balasubramani
  • Ravindra Kamath
  • Baskaran Rajasekaran
  • Shunquian Jin

Detail Information

Publications6

  1. pmc Chromatin modifications and the DNA damage response to ionizing radiation
    Rakesh Kumar
    Department of Radiation Oncology, University of Texas Southwestern Medical Center Dallas, TX, USA
    Front Oncol 2:214. 2012
    ..In this review, we will summarize chromatin modifications by the respective chromatin modifying factors that occur during the DNA damage response...
  2. ncbi request reprint The role of inflammatory pathways in cancer-associated cachexia and radiation resistance
    Aaron Laine
    University of Texas Southwestern Medical Center, Department of Radiation Oncology, 5801 Forest Park Road, Dallas, TX 75235
    Mol Cancer Res 11:967-72. 2013
    ..Herein we discuss the role of inflammatory pathways in CAC and examine the potential link between cachexia induction and radiation resistance...
  3. pmc Genome-wide distribution of histone H4 Lysine 16 acetylation sites and their relationship to gene expression
    Nobuo Horikoshi
    Department of Radiation Oncology, Division of Molecular Radiation Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
    Genome Integr 4:3. 2013
    ..However, in mammalian cells, H4K16ac is not associated with dosage compensation and the genomic distribution of H4K16ac is not precisely known. Therefore, we have mapped the genome-wide H4K16ac distribution in human cells...
  4. doi request reprint Histone H4 lysine 16 acetylated isoform synthesis opens new route to biophysical studies
    Tej K Pandita
    Department of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
    Proteomics 13:1546-7. 2013
    ..This paper describes an improved method to prepare acetylated H4K16 as well as other covalently modified histone H4 isoform for biophysical studies...
  5. doi request reprint 14th International Workshop on Ataxia-Telangiectasia ATW2012
    Tej K Pandita
    Department of Radiation Oncology, University of Texas South Western Medical Center, Dallas, TX 75390, USA Electronic address
    DNA Repair (Amst) 11:853-6. 2012
    ..This report summarizes below a sampling of the many interesting results from the meeting...
  6. pmc Tip60-mediated acetylation activates transcription independent apoptotic activity of Abl
    Zhihua Jiang
    Department of Microbiology and Molecular Genetics, Pittsburgh, PA 15240, USA
    Mol Cancer 10:88. 2011
    ..However, the mechanism/s leading to activation of Abl's apoptotic activity is currently unknown...

Research Grants15

  1. Functional Characterization of the Mammalian MOF Gene Product
    Tej K Pandita; Fiscal Year: 2009
    ..Ultimately, understanding the basis for biochemical differences in chromatin structure between normal and tumor tissue could provide strategies for modifying the response to IR that could be useful in clinical radiation therapy. ..
  2. Tumor-cell-specific targets for combined hyperthermia and radiation effects
    Tej K Pandita; Fiscal Year: 2010
    ..If the proposed research is successfully carried out, the novel information generated from the proposed studies will be useful in designing tumor specific therapies. ..
  3. CHROMATIN MODIFYING FACTORS CONTROL RADIATION RESPONSE AND GENOMIC STABILITY
    Tej K Pandita; Fiscal Year: 2010
    ..Thus understanding these mechanisms is critical to both cancer prevention as well as development of strategies to optimize targeted and combinatorial treatment regimens with regard to the disease Ataxia- Telangiectasia. ..
  4. Functional Characterization of the Mammalian MOF Gene Product
    Tej K Pandita; Fiscal Year: 2010
    ..Ultimately, understanding the basis for biochemical differences in chromatin structure between normal and tumor tissue could provide strategies for modifying the response to IR that could be useful in clinical radiation therapy. ..
  5. Functional Characterization of the Mammalian MOF Gene Product
    TEJ PANDITA; Fiscal Year: 2009
    ..Ultimately, understanding the basis for biochemical differences in chromatin structure between normal and tumor tissue could provide strategies for modifying the response to IR that could be useful in clinical radiation therapy. ..
  6. CHROMATIN-TELOMERE STRUCTURE AND AT GENOMIC SENSITIVITY
    TEJ PANDITA; Fiscal Year: 2005
    ..These studies will provide information impacting on understanding how ATM influences telomere chromatin structure, which in turn will help to define the role of ATM in maintaining genome integrity and normal cellular behavior. ..
  7. CHROMATIN-TELOMERE STRUCTURE AND AT GENOMIC SENSITIVITY
    TEJ PANDITA; Fiscal Year: 2002
    ..These studies will provide information impacting on understanding how ATM influences telomere chromatin structure, which in turn will help to define the role of ATM in maintaining genome integrity and normal cellular behavior. ..
  8. CHROMATIN-TELOMERE STRUCTURE AND AT GENOMIC SENSITIVITY
    TEJ PANDITA; Fiscal Year: 2002
    ..These studies will provide information impacting on understanding how ATM influences telomere chromatin structure, which in turn will help to define the role of ATM in maintaining genome integrity and normal cellular behavior. ..
  9. CHROMATIN-TELOMERE STRUCTURE AND AT GENOMIC SENSITIVITY
    TEJ PANDITA; Fiscal Year: 2001
    ..These studies will provide information impacting on understanding how ATM influences telomere chromatin structure, which in turn will help to define the role of ATM in maintaining genome integrity and normal cellular behavior. ..
  10. CHROMATIN-TELOMERE STRUCTURE AND AT GENOMIC SENSITIVITY
    TEJ PANDITA; Fiscal Year: 2000
    ..These studies will provide information impacting on understanding how ATM influences telomere chromatin structure, which in turn will help to define the role of ATM in maintaining genome integrity and normal cellular behavior. ..
  11. CHROMATIN MODIFYING FACTORS CONTROL RADIATION RESPONSE AND GENOMIC STABILITY
    Tej K Pandita; Fiscal Year: 2009
    ..Thus understanding these mechanisms is critical to both cancer prevention as well as development of strategies to optimize targeted and combinatorial treatment regimens with regard to the disease Ataxia- Telangiectasia. ..