Gregory M Palmer

Summary

Affiliation: University of Wisconsin
Country: USA

Publications

  1. ncbi request reprint Comparison of multiexcitation fluorescence and diffuse reflectance spectroscopy for the diagnosis of breast cancer (March 2003)
    Gregory M Palmer
    Department of Biomedical Engineering, University of Wisconsin, Madison, WI 53706, USA
    IEEE Trans Biomed Eng 50:1233-42. 2003
  2. ncbi request reprint Monte Carlo-based inverse model for calculating tissue optical properties. Part II: Application to breast cancer diagnosis
    Gregory M Palmer
    Department of Biomedical Engineering, 136 Hudson Hall, Box 90281, Duke University, Durham, North Carolina 27708 0281, USA
    Appl Opt 45:1072-8. 2006
  3. doi request reprint Cost-effective diffuse reflectance spectroscopy device for quantifying tissue absorption and scattering in vivo
    Bing Yu
    Duke University, Department of Biomedical Engineering, Durham, North Carolina 27708 0281, USA
    J Biomed Opt 13:060505. 2008
  4. ncbi request reprint A strategy for quantitative spectral imaging of tissue absorption and scattering using light emitting diodes and photodiodes
    Justin Y Lo
    Department of Biomedical Engineering, Duke University, Durham, NC 27708, USA
    Opt Express 17:1372-84. 2009
  5. ncbi request reprint Autofluorescence and diffuse reflectance properties of malignant and benign breast tissues
    Tara M Breslin
    Department of Surgery, University of Wisconsin Madison, Madison, Wisconsin 53792, USA
    Ann Surg Oncol 11:65-70. 2004
  6. pmc A robust Monte Carlo model for the extraction of biological absorption and scattering in vivo
    Janelle E Bender
    Department of Biomedical Engineering, Duke University, Durham, NC 27708, USA
    IEEE Trans Biomed Eng 56:960-8. 2009
  7. pmc Diagnosis of breast cancer using fluorescence and diffuse reflectance spectroscopy: a Monte-Carlo-model-based approach
    Changfang Zhu
    University of Wisconsin Madison, Department of Electrical and Computer Engineering, Madison, Wisconsin 53705, USA
    J Biomed Opt 13:034015. 2008
  8. ncbi request reprint Diagnosis of breast cancer using diffuse reflectance spectroscopy: Comparison of a Monte Carlo versus partial least squares analysis based feature extraction technique
    Changfang Zhu
    Department of Electrical and Computer Engineering, University of Wisconsin, Madison, Wisconsin 53705, USA
    Lasers Surg Med 38:714-24. 2006
  9. ncbi request reprint Effect of optical clearing agents on the in vivo optical properties of squamous epithelial tissue
    Stacy R Millon
    Department of Biomedical Engineering, University of Wisconsin, Madison, Wisconsin 53706, USA
    Lasers Surg Med 38:920-7. 2006
  10. pmc Electromagnetic spectroscopy of normal breast tissue specimens obtained from reduction surgeries: comparison of optical and microwave properties
    Mariya Lazebnik
    Department of Electrical and Computer Engineering, University of Wisconsin, Madison, WI 53706, USA
    IEEE Trans Biomed Eng 55:2444-51. 2008

Collaborators

Detail Information

Publications20

  1. ncbi request reprint Comparison of multiexcitation fluorescence and diffuse reflectance spectroscopy for the diagnosis of breast cancer (March 2003)
    Gregory M Palmer
    Department of Biomedical Engineering, University of Wisconsin, Madison, WI 53706, USA
    IEEE Trans Biomed Eng 50:1233-42. 2003
    ..The fluorescence excitation-emission wavelengths identified as being diagnostic from the PCA-SVM algorithm suggest that the important fluorophores for breast cancer diagnosis are most likely tryptophan, NAD(P)H and flavoproteins...
  2. ncbi request reprint Monte Carlo-based inverse model for calculating tissue optical properties. Part II: Application to breast cancer diagnosis
    Gregory M Palmer
    Department of Biomedical Engineering, 136 Hudson Hall, Box 90281, Duke University, Durham, North Carolina 27708 0281, USA
    Appl Opt 45:1072-8. 2006
    ....
  3. doi request reprint Cost-effective diffuse reflectance spectroscopy device for quantifying tissue absorption and scattering in vivo
    Bing Yu
    Duke University, Department of Biomedical Engineering, Durham, North Carolina 27708 0281, USA
    J Biomed Opt 13:060505. 2008
    ....
  4. ncbi request reprint A strategy for quantitative spectral imaging of tissue absorption and scattering using light emitting diodes and photodiodes
    Justin Y Lo
    Department of Biomedical Engineering, Duke University, Durham, NC 27708, USA
    Opt Express 17:1372-84. 2009
    ..Simulated crosstalk analysis indicates that this evolving system can be multiplexed for spectral imaging in the future...
  5. ncbi request reprint Autofluorescence and diffuse reflectance properties of malignant and benign breast tissues
    Tara M Breslin
    Department of Surgery, University of Wisconsin Madison, Madison, Wisconsin 53792, USA
    Ann Surg Oncol 11:65-70. 2004
    ..We hypothesized that a statistically significant difference would be demonstrated between benign and malignant breast tissues on the basis of their unique fluorescence and reflectance properties...
  6. pmc A robust Monte Carlo model for the extraction of biological absorption and scattering in vivo
    Janelle E Bender
    Department of Biomedical Engineering, Duke University, Durham, NC 27708, USA
    IEEE Trans Biomed Eng 56:960-8. 2009
    ..We found the best reference-target phantom combinations to be ones with similar scattering levels. The results from these phantom studies provide a set of guidelines for extracting optical parameters from clinical studies...
  7. pmc Diagnosis of breast cancer using fluorescence and diffuse reflectance spectroscopy: a Monte-Carlo-model-based approach
    Changfang Zhu
    University of Wisconsin Madison, Department of Electrical and Computer Engineering, Madison, Wisconsin 53705, USA
    J Biomed Opt 13:034015. 2008
    ....
  8. ncbi request reprint Diagnosis of breast cancer using diffuse reflectance spectroscopy: Comparison of a Monte Carlo versus partial least squares analysis based feature extraction technique
    Changfang Zhu
    Department of Electrical and Computer Engineering, University of Wisconsin, Madison, Wisconsin 53705, USA
    Lasers Surg Med 38:714-24. 2006
    ..A physical model (Monte Carlo inverse model) and an empirical model (partial least squares analysis) based approach, were compared for extracting diagnostic features from the diffuse reflectance spectra...
  9. ncbi request reprint Effect of optical clearing agents on the in vivo optical properties of squamous epithelial tissue
    Stacy R Millon
    Department of Biomedical Engineering, University of Wisconsin, Madison, Wisconsin 53706, USA
    Lasers Surg Med 38:920-7. 2006
    ..This paper quantifies tissue optical properties of the hamster cheek pouch model in order to provide a means to assess the effect of OCAs quantitatively in vivo...
  10. pmc Electromagnetic spectroscopy of normal breast tissue specimens obtained from reduction surgeries: comparison of optical and microwave properties
    Mariya Lazebnik
    Department of Electrical and Computer Engineering, University of Wisconsin, Madison, WI 53706, USA
    IEEE Trans Biomed Eng 55:2444-51. 2008
    ..55, p<0.01). Our results suggest that combining optical and microwave modalities for analyzing breast tissue samples may serve as a crosscheck and provide complementary information about tissue composition...
  11. ncbi request reprint Use of a multiseparation fiber optic probe for the optical diagnosis of breast cancer
    Changfang Zhu
    University of Wisconsin Madison, Department of Electrical and Computer Engineering, Madison, Wisconsin 53706, USA
    J Biomed Opt 10:024032. 2005
    ....
  12. pmc Advances in quantitative UV-visible spectroscopy for clinical and pre-clinical application in cancer
    J Quincy Brown
    Department of Biomedical Engineering, Duke University, Durham, NC 27708, USA
    Curr Opin Biotechnol 20:119-31. 2009
    ....
  13. pmc Quantitative optical spectroscopy: a robust tool for direct measurement of breast cancer vascular oxygenation and total hemoglobin content in vivo
    J Quincy Brown
    Department of Biomedical Engineering, Duke University, Durham, North Carolina 27708, USA
    Cancer Res 69:2919-26. 2009
    ..Diffuse reflectance spectroscopy could aid in prognosis and prediction in breast cancer via quantitative assessment of tumor physiology at the time of diagnostic biopsy...
  14. pmc Investigation of fiber-optic probe designs for optical spectroscopic diagnosis of epithelial pre-cancers
    Melissa C Skala
    Department of Biomedical Engineering, University of Wisconsin, 1550 Engineering Drive, Madison, WI 53706, USA
    Lasers Surg Med 34:25-38. 2004
    ..The second objective was to design a novel, angled illumination fiber-optic probe to maximally exploit the depth-dependent fluorescence properties of epithelial tissues...
  15. ncbi request reprint Autofluorescence spectroscopy of normal and malignant human breast cell lines
    Gregory M Palmer
    Department of Biomedical Engineering, University of Wisconsin, Madison, WI 53706, USA
    Photochem Photobiol 78:462-9. 2003
    ..In conclusion, the differences in normal and malignant human breast tissue fluorescence spectra may be attributed in part to differences in the intrinsic cellular fluorescence of normal and malignant breast epithelial cells...
  16. ncbi request reprint Monte Carlo-based inverse model for calculating tissue optical properties. Part I: Theory and validation on synthetic phantoms
    Gregory M Palmer
    Department of Biomedical Engineering, 136 Hudson Hall, Box 90281, Duke University, Durham, North Carolina 27708 0281, USA
    Appl Opt 45:1062-71. 2006
    ..It was found that optical properties could be extracted from the experimentally measured diffuse reflectance spectra with an average error of 3% or less for phantoms containing hemoglobin and 12% or less for phantoms containing Nigrosin...
  17. ncbi request reprint Steady-state fluorescence imaging of neoplasia
    Erin M Gill
    Department of Biomedical Engineering, University of Wisconsin, Madison, Wisconsin 53706, USA
    Methods Enzymol 361:452-81. 2003
  18. ncbi request reprint Optimal methods for fluorescence and diffuse reflectance measurements of tissue biopsy samples
    Gregory M Palmer
    Department of Biomedical Engineering, University of Wisconsin, Madison, Wisconsin 53706, USA
    Lasers Surg Med 30:191-200. 2002
    ..This study investigates the optimal tissue handling methods for in vitro fluorescence spectroscopy studies...
  19. pmc Monte-Carlo-based model for the extraction of intrinsic fluorescence from turbid media
    Gregory M Palmer
    Duke University, Department of Radiation Oncology, Box 3455, Durham, North Carolina 27710, USA
    J Biomed Opt 13:024017. 2008
    ..It is found that this model is able to retrieve the intrinsic fluorescence spectra of the tissue phantoms and recover the intrinsic fluorescence intensity of furan within the phantoms to within a mean error of less than 10%...
  20. ncbi request reprint Use of genetic algorithms to optimize fiber optic probe design for the extraction of tissue optical properties
    Gregory M Palmer
    Department of Radiation Oncology, Duke University, Durham, NC 27710, USA
    IEEE Trans Biomed Eng 54:1533-5. 2007
    ..30 cm(-1) for the reduced scattering coefficient (tested range of 3-40 cm(-1)), and 0.41 cm(-1) for the absorption coefficient (tested range of 0-80 cm(-1))...