Research Topics
| BARTON PALMERSummaryAffiliation: University of California Country: USA Publications
Research Grants
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Detail Information
Publications
Anxiety disorders in the elderly: DSM-IV and other barriers to diagnosis and treatmentB W Palmer
University of California, San Diego and San Diego VA Medical Center, Department of Psychiatry, 92161, USA
J Affect Disord 46:183-90. 1997..An open-minded approach unhinged by 'conventional wisdom' is warranted...- Decisional capacity to consent to research among patients with bipolar disorder: comparison with schizophrenia patients and healthy subjectsBarton W Palmer
Department of Psychiatry, University of California, San Diego, Veterans Affairs San Diego Healthcare System, Calif 92161, USA
J Clin Psychiatry 68:689-96. 2007.... - The association of specific neuropsychological deficits with capacity to consent to research or treatmentBarton W Palmer
Department of Psychiatry, University of California, San Diego, La Jolla, California 92161, USA
J Int Neuropsychol Soc 13:1047-59. 2007..These ongoing efforts represent an important conceptual and empirical bridge between bioethical, legal, and neuropsychological approaches to understanding meaningful decision-making processes... - Relationship of individual cognitive abilities to specific components of decisional capacity among middle-aged and older patients with schizophreniaBarton W Palmer
Department of Psychiatry, University of California, San Diego, USA
Schizophr Bull 32:98-106. 2006..Also, an interactive dialogue between patient and investigator with repeated presentation of information is likely to aid understanding of disclosed information among patients with schizophrenia... - Assessment of capacity to consent to research among older persons with schizophrenia, Alzheimer disease, or diabetes mellitus: comparison of a 3-item questionnaire with a comprehensive standardized capacity instrumentBarton W Palmer
Department of Psychiatry, University of California, San Diego, USA
Arch Gen Psychiatry 62:726-33. 2005..Also, as requirements for formal assessment of decisional capacity are becoming more common, there is a clear need to identify efficient screening methods... - Informed consent for schizophrenia research: what is an investigator (or IRB) to do?Barton W Palmer
Department of Psychiatry, University of California San Diego, San Diego, CA 92093-0603, USA
Behav Sci Law 24:447-52. 2006 - What do we know about neuropsychological aspects of schizophrenia?Barton W Palmer
University of California, San Diego, 9500 Gilman Drive 0603V, La Jolla, CA 92093 0603, USA
Neuropsychol Rev 19:365-84. 2009.... - Do people with schizophrenia have differential impairment in episodic memory and/or working memory relative to other cognitive abilities?Barton W Palmer
Department of Psychiatry, University of California, San Diego, La Jolla, CA, USA
Schizophr Res 116:259-65. 2010.... - Correlates of treatment-related decision-making capacity among middle-aged and older patients with schizophreniaBarton W Palmer
Department of Psychiatry, University of California San Diego, the Veterans Medical Research Foundation, Veterans Affairs San Diego Healthcare System, San Diego, CA 92161, USA
Arch Gen Psychiatry 61:230-6. 2004..We examined the range, stability, and correlates of treatment-related decisional capacity in this patient population... - Treatment-related decision-making capacity in middle-aged and older patients with psychosis: a preliminary study using the MacCAT-T and HCATBarton W Palmer
Department of Psychiatry, University of California, San Diego, USA
Am J Geriatr Psychiatry 10:207-11. 2002..Results point to the importance of assessing DMC and to the potential modifiability of initial difficulties in understanding... - Heterogeneity in functional status among older outpatients with schizophrenia: employment history, living situation, and drivingBarton W Palmer
Department of Psychiatry, University of California, San Diego, 92161, USA
Schizophr Res 55:205-15. 2002..These findings counter notions that functional impairment is inevitable in older schizophrenia patients, and highlight the importance of assessment of functional skills and possibly targeting them as a treatment focus... - Are late-onset schizophrenia spectrum disorders neurodegenerative conditions? Annual rates of change on two dementia measuresBarton W Palmer
Department of Psychiatry, University of California, San Diego, USA
J Neuropsychiatry Clin Neurosci 15:45-52. 2003..Cognitive changes among LOSD patients were similar to those in EOSD patients and NCs, whereas the AD groups had greater declines. Results support viewing LOSDs as static encephalopathies... - Older patients with schizophrenia: challenges in the coming decadesB W Palmer
Department of Psychiatry at the University of California, San Diego, USA
Psychiatr Serv 50:1178-83. 1999.... - The relationship of neuropsychological abilities to specific domains of functional capacity in older schizophrenia patientsJovier D Evans
Department of Psychiatry, University of California, San Diego, California, USA
Biol Psychiatry 53:422-30. 2003..This is consistent with findings of relatively generalized, intercorrelated cognitive impairment in schizophrenia and multiply determined domains of everyday functioning... - Stability of cognitive performance in older patients with schizophrenia: an 8-week test-retest studyPhilip D Harvey
Department of Psychiatry, Mt Sinai School of Medicine, New York, NY 10029, USA
Am J Psychiatry 162:110-7. 2005..There are several factors that could lead to spurious improvements in cognitive test scores, including practice effects and random test-retest errors... - Worth the risk? Relationship of incentives to risk and benefit perceptions and willingness to participate in schizophrenia researchLaura B Dunn
Department of Psychiatry, University of California, San Francisco, 401 Parnassus Avenue, Box GPP 0984, San Francisco, CA 94143, USA
Schizophr Bull 35:730-7. 2009..We examined willingness to participate in research, in relation to perceived risks and benefits, among people with schizophrenia and schizoaffective disorder... - A six-factor model of cognition in schizophrenia and related psychotic disorders: relationships with clinical symptoms and functional capacityJulie Akiko Gladsjo
Department of Psychiatry, University of California, San Diego 92161, USA
Schizophr Bull 30:739-54. 2004..A simultaneous confirmatory factor analysis using the original sample and a group of healthy subjects (n = 131) demonstrated that the six-factor model of cognition was generalizable and applied equally well to both groups... - A guide for considering performance-based assessments when determining a patient's capacity for safe, independent livingDavid J Moore
Department of Psychiatry, University of California, San Diego, USA
Geriatrics 63:16-20. 2008.... - Sustained use of CPAP slows deterioration of cognition, sleep, and mood in patients with Alzheimer's disease and obstructive sleep apnea: a preliminary studyJana R Cooke
Department of Medicine, University of California, San Diego, CA, USA
J Clin Sleep Med 5:305-9. 2009..Continuous positive airway pressure (CPAP) has recently been shown to have beneficial effects on cognition in AD. Little attention has focused on the long-term benefits of CPAP in these patients... - Neurocognitive effects of antipsychotic medications in patients with chronic schizophrenia in the CATIE TrialRichard S E Keefe
Department of Psychiatry, John Umstead Hospital, Duke University Medical Center, Durham, NC 27710, USA
Arch Gen Psychiatry 64:633-47. 2007..The relative effect of the second-generation (atypical) antipsychotic drugs and older agents on neurocognition has not been comprehensively determined... - Neurocognitive impairment in middle-aged and older adults with bipolar disorder: comparison to schizophrenia and normal comparison subjectsColin A Depp
Department of Psychiatry, University of California, San Diego, United States
J Affect Disord 101:201-9. 2007..We examined neurocognitive abilities in middle-aged and older adults with bipolar disorder to groups with schizophrenia or normal subjects, as well as the relation of neurocognition to clinical characteristics... - Prevalence and correlates of adequate performance on a measure of abilities related to decisional capacity: differences among three standards for the MacCAT-CR in patients with schizophreniaLaura B Dunn
University of California, San Diego, Department of Psychiatry, United States
Schizophr Res 89:110-8. 2007..These findings underscore the need for refinement of capacity assessment procedures and for improvements in the use of capacity assessment tools for screening purposes and to assist in categorical capacity determinations... - A new brief instrument for assessing decisional capacity for clinical researchDilip V Jeste
Department of Psychiatry, University of California, San Diego, Veterans Affairs San Diego Healthcare System, Bldg 13, Fourth Floor, 3350 La Jolla Village Dr, San Diego, CA 92161, USA
Arch Gen Psychiatry 64:966-74. 2007..However, there are few reliable and validated brief tools that could be used routinely to evaluate individuals' capacity to consent to a research protocol... - Divergent trajectories of physical, cognitive, and psychosocial aging in schizophreniaDilip V Jeste
Department of Psychiatry and Sam and Rose Stein Institute for Research on Aging, University of California, San Diego, La Jolla, CA 92093, USA
Schizophr Bull 37:451-5. 2011..At the same time, effective psychotherapeutic interventions can affect brain structure and function and produce lasting positive behavioral changes in aging adults with schizophrenia... - Subsyndromal depressive symptoms in middle-aged and older persons with schizophreniaSidney Zisook
Department of Psychiatry, University of California San Diego, La Jolla, CA 92093, USA
Am J Geriatr Psychiatry 15:1005-14. 2007.... - Multimedia consent for research in people with schizophrenia and normal subjects: a randomized controlled trialDilip V Jeste
University of California, San Diego, USA
Schizophr Bull 35:719-29. 2009.... - Assessment of medication management ability in middle-aged and older adults with bipolar disorderColin A Depp
Department of Psychiatry, University of California, San Diego, CA, USA
J Clin Psychopharmacol 28:225-9. 2008..This small cross-sectional study suggests that deficits in medication management ability may be present in later-life BD. Neurocognitive deficits may be important in understanding problems with unintentional nonadherence... - Cognitive effects of treating obstructive sleep apnea in Alzheimer's disease: a randomized controlled studySonia Ancoli-Israel
Departments of Psychiatry, University of California, San Diego, La Jolla, California, USA
J Am Geriatr Soc 56:2076-81. 2008..To examine whether treatment of obstructive sleep apnea (OSA) with continuous positive airway pressure (CPAP) in patients with Alzheimer's disease (AD) results in better cognitive function... - Short-term course of neuropsychological abilities in middle-aged and older adults with bipolar disorderColin A Depp
Department of Psychiatry, University of California at San Diego, San Diego, CA 92161, USA
Bipolar Disord 10:684-90. 2008..There are few longitudinal studies of neurocognition in bipolar disorder, and the short-term course of cognitive deficits in later-life bipolar disorder is unknown... - Evaluation of specific executive functioning skills and the processes underlying executive control in schizophreniaGauri N Savla
Department of Psychiatry, University of California, San Diego, La Jolla, California 92093 0603, USA
J Int Neuropsychol Soc 17:14-23. 2011..However, the results from one task suggest that there might be additional impairment in some aspects of executive control... - Physical and mental health-related quality of life among older people with schizophreniaDavid P Folsom
University of California, San Diego, VA San Diego Healthcare System, 3350 La Jolla Village Drive, San Diego, CA 92161, USA
Schizophr Res 108:207-13. 2009..The objective of this study was to examine the relationship of age to both mental and physical aspects of HRQoL in individuals with schizophrenia as compared to normal comparison subjects (NCs)... - Performance-based and subjective measures of functioning in middle-aged and older adults with bipolar disorderColin A Depp
Department of Psychiatry, University of California, San Diego VA San Diego Healthcare System, 3350 La Jolla Village Drive 116A 1, San Diego, CA 92161, USA
J Nerv Ment Dis 197:471-5. 2009..Given its relative independence from symptoms, the UPSA may be useful in gauging the effectiveness of rehabilitation for bipolar disorder... - Correlates of spirituality in older womenIpsit V Vahia
Sam and Rose Stein Institute for Research on Aging, University of California, San Diego, La Jolla, 92093, USA
Aging Ment Health 15:97-102. 2011.... - Exergames for subsyndromal depression in older adults: a pilot study of a novel interventionDori Rosenberg
Joint Doctoral Program in Clinical Psychology University of California San Diego UCSD San Diego State University SDSU, San Diego, CA, USA
Am J Geriatr Psychiatry 18:221-6. 2010..The authors assessed the feasibility, acceptability, and short-term efficacy and safety of a novel intervention using exergames (entertaining video games that combine game play with exercise) for SSD in older adults... - Assessing decisional capacity for clinical research or treatment: a review of instrumentsLaura B Dunn
Department of Psychiatry, 0603 V, University of California, San Diego, La Jolla, CA 92093 0603, USA
Am J Psychiatry 163:1323-34. 2006..The authors critically reviewed existing measures of decisional capacity for research and treatment... - Improving understanding of research consent in middle-aged and elderly patients with psychotic disordersLaura B Dunn
Department of Psychiatry, University of California, San Diego, USA
Am J Geriatr Psychiatry 10:142-50. 2002..Interestingly, EC patients did not differ significantly from RC normal comparison subjects in their post-test scores. Among the patients, comprehension test scores correlated with level of education and cognitive performance... - Magnitude of impairment in decisional capacity in people with schizophrenia compared to normal subjects: an overviewDilip V Jeste
Department of Psychiatry, University of California, San Diego, USA
Schizophr Bull 32:121-8. 2006.... - Understanding of placebo controls among older people with schizophreniaLaura B Dunn
Department of Psychiatry, University of California, San Diego, USA
Schizophr Bull 32:137-46. 2006..We conclude that the level of understanding of important research design-related information is not static but may be influenced by how investigators approach the consent process... - Use of the mini-mental state exam in middle-aged and older outpatients with schizophrenia: cognitive impairment and its associationsDavid J Moore
Department of Psychiatry, University of California, San Diego, CA 92161, USA
Am J Geriatr Psychiatry 12:412-9. 2004.... - Tennessee WilliamsNeelum D Jeste
University of California, San Diego, VA San Diego Healthcare System 116A 1, 3350 La Jolla Village Dr, San Diego, CA 92161, USA
Am J Geriatr Psychiatry 12:370-5. 2004..Despite his mental illness, Williams continued to be a productive writer even after age 60, although his later works were less successful. The authors consider both the strengths and limitations of Williams' coping mechanisms... - Anxiety symptoms and quality of life in middle-aged and older outpatients with schizophrenia and schizoaffective disorderJulie Loebach Wetherell
Department of Psychiatry, University of California, San Diego, La Jolla, CA 92093 0603, USA
J Clin Psychiatry 64:1476-82. 2003..This study examined whether anxiety symptoms make an independent contribution to poorer quality of life among middle-aged and older outpatients with schizophrenia or schizoaffective disorder... - A collaborative model for research on decisional capacity and informed consent in older patients with schizophrenia: bioethics unit of a geriatric psychiatry intervention research centerDilip V Jeste
Department of Psychiatry and Neurosciences, University of California San Diego and VA San Diego Healthcare System, San Diego, CA 92161 USA
Psychopharmacology (Berl) 171:68-74. 2003.... - Generalized cognitive impairments, ability to perform everyday tasks, and level of independence in community living situations of older patients with psychosisElizabeth W Twamley
UCSD Department of Psychiatry, VA San Diego Healthcare System 116A 1, 3350 La Jolla Village Drive, La Jolla, CA 92161, USA
Am J Psychiatry 159:2013-20. 2002.... - A review of performance-based measures of functional living skillsDavid J Moore
Department of Psychiatry, University of California, VA San Diego Healthcare System, 116A 13, 3350 La Jolla Village Drive, San Diego, CA 92161, United States
J Psychiatr Res 41:97-118. 2007.... - An evaluation of longitudinal neurocognitive performance among middle-aged and older schizophrenia patients: use of mixed-model analysesGauri Nayak Savla
San Diego State University University of California, San Diego Joint Doctoral, Program in Clinical Psychology, 6363 Alvarado Court, Suite 103, San Diego, CA 92120 4913, USA
Schizophr Res 83:215-23. 2006..In sum, we found cognitive impairment to be stable over time among outpatients with schizophrenia, regardless of the statistical methodology used to analyze longitudinal data... - Verbal fluency impairments among middle-aged and older outpatients with schizophrenia are characterized by deficient switchingDavid J Moore
University of California, San Diego UCSD, Department of Psychiatry, Division of Geriatric Psychiatry, 9500 Gilman Drive, 0603V, La Jolla, CA 92093 0603, USA
Schizophr Res 87:254-60. 2006..Further delineation of the cognitive mechanisms of the observed lexical-semantic switching deficits in schizophrenia should be a focus of future research... - Assessment of therapeutic misconception in older schizophrenia patients with a brief instrumentLaura B Dunn
Department of Psychiatry, University of California, San Diego, La Jolla, CA 92161, USA
Am J Psychiatry 163:500-6. 2006..How best to assess therapeutic misconception is unclear. Also unclear is to what degree patients with severe mental illnesses, such as schizophrenia, may manifest these beliefs... - Transient and executive function working memory in schizophreniaElizabeth W Twamley
University of California, San Diego, Department of Psychiatry, 140 Arbor Drive, San Diego, CA 92103, USA
Schizophr Res 87:185-90. 2006..These results do not reflect differential executive function working memory dysfunction in schizophrenia, but appear to support transient and executive function working memory as separable constructs... - Adherence to continuous positive airway pressure treatment in patients with Alzheimer's disease and obstructive sleep apneaLiat Ayalon
Department of Psychiatry, University of California, San Diego, San Diego, CA, and Veterans Affairs San Diego Health Care System, San Diego, CA 92161, USA
Am J Geriatr Psychiatry 14:176-80. 2006..32, p=0.03) during the trial. CONCLUSION: Patients with AD with obstructive sleep apnea can tolerate CPAP. Adherence and long-term use may be more difficult among those patients with more depressive symptoms... - Adjudicative competenceSharron E Dawes
Department of Psychiatry, University of California San Diego, USA
Curr Opin Psychiatry 21:490-4. 2008..In this report we provide a brief overview regarding the general concept of adjudicative competence and its assessment, as well as some highlights of recent empirical studies on this topic... - Rohling's Interpretive Method and inherent limitations on the flexibility of "flexible batteries"Barton W Palmer
Department of Psychiatry, University of California, San Diego, La Jolla, CA 92093-0603, USA
Neuropsychol Rev 14:171-6; discussion 155-69. 2004..As an alternative, we suggest the value of developing and using co-normed comprehensive neuropsychological test batteries from which test users might select subsets of tests... - Continuous positive airway pressure reduces subjective daytime sleepiness in patients with mild to moderate Alzheimer's disease with sleep disordered breathingMei S Chong
Department of Psychiatry, Univeristy of California at San Diego, San Diego, CA 92161, USA
J Am Geriatr Soc 54:777-81. 2006..68 to 6.47 (P=.01) after 3 weeks of therapeutic CPAP. CONCLUSION: These data provide evidence of the effectiveness of CPAP in reducing subjective daytime sleepiness in patients with AD with SDB... - Schizophrenia in late life: emerging issuesDavid P Folsom
University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093-0664, USA
Dialogues Clin Neurosci 8:45-52. 2006..Clinical care for this ever-increasing segment of our population requires special consideration of the unique characteristics of older persons with schizophrenia... - Effective use of consent forms and interactive questions in the consent processBarton W Palmer
Division of Geriatric Psychiatry, University of California, San Diego, USA
IRB 30:8-12. 2008 - The effect of sleep-disordered breathing on stages of sleep in patients with Alzheimer's diseaseJana R Cooke
Department of Medicine, University of California, San Diego, Veterans Affairs San Diego Healthcare System, CA, USA
Behav Sleep Med 4:219-27. 2006..Treating these patients' SDB may increase their amount of REM sleep, which may result in improved daytime functioning. Controlled trials of SDB treatment in AD are needed to answer this question... - Baseline neurocognitive deficits in the CATIE schizophrenia trialRichard S E Keefe
Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC 27710, USA
Neuropsychopharmacology 31:2033-46. 2006..Multiple analyses suggested that a broad cognitive deficit characterizes this sample. These deficits are modestly related to negative symptoms and essentially independent of positive symptom severity... - Meta-consent in research on decisional capacity: a "Catch-22"?Elyn R Saks
University of Southern California Law School, USA
Schizophr Bull 32:42-6. 2006.... - The expanding role of neuropsychology in geriatric psychiatryBarton W Palmer
Am J Geriatr Psychiatry 12:338-41. 2004 - Comparison of two enhanced consent procedures for patients with mild Alzheimer disease or mild cognitive impairmentDinesh Mittal
Center for Mental Healthcare and Outcomes Research, Central Arkansas Veterans Healthcare System, North Little Rock, Arkansas 72114, USA
Am J Geriatr Psychiatry 15:163-7. 2007.... - Cognitive predictors of medication adherence among middle-aged and older outpatients with schizophreniaShafali D Jeste
Children's Hospital Boston, Boston, MA 02115, USA
Schizophr Res 63:49-58. 2003....
Research Grants
- Enhancing Consent for Alzheimer ResearchBARTON PALMER; Fiscal Year: 2009..This study's relevance derives from the idea that enhanced consent may foster comprehension as AD patients are asked to provide consent or assent to participate in clinical research. ..
- Capacity to Consent to Research on Bipolar DisorderBARTON PALMER; Fiscal Year: 2009..The data collected in the proposed study will be a key component in filling this vital informational gap. ..
- Enhancing Consent for Alzheimer ResearchBARTON PALMER; Fiscal Year: 2007..This study's relevance derives from the idea that enhanced consent may foster comprehension as AD patients are asked to provide consent or assent to participate in clinical research. ..
- CAPACITY TO CONSENT TO RESEARCH ON PSYCHOSISBARTON PALMER; Fiscal Year: 2006..We further hypothesize that fluctuations in capacity from baseline to the 3-month, 1-year, and 2-year followups will be accompanied by parallel changes in insight deficits and severity of psychiatric symptoms. ..
- Ensuring Informed Consent Delivery As A ProcessBARTON PALMER; Fiscal Year: 2003..With this experience, we will then hold two 60 minute seminars (one at each facility) to disseminate the procedures developed for wider use by all researchers at each of the two facilities. ..
- Evidence-Based Improvement in the Consenting ProcessBARTON PALMER; Fiscal Year: 2002..We are committed to continue educational activities beyond the project period of this request for funding. ..
- TREATMENT DECISION MAKING CAPACITY IN SCHIZOPHRENIABARTON PALMER; Fiscal Year: 2002..abstract_text> ..
- Enhancing Consent for Alzheimer ResearchBarton W Palmer; Fiscal Year: 2010..This study's relevance derives from the idea that enhanced consent may foster comprehension as AD patients are asked to provide consent or assent to participate in clinical research. ..