Joel Palefsky

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi request reprint Human papillomavirus-related tumors in HIV
    Joel Palefsky
    Department of Medicine, University of California, San Francisco, California 94143, USA
    Curr Opin Oncol 18:463-8. 2006
  2. pmc HPV infection in men
    Joel M Palefsky
    Department of Medicine, University of California, San Francisco, CA 94143, USA
    Dis Markers 23:261-72. 2007
  3. pmc Human papillomavirus-related disease in people with HIV
    Joel Palefsky
    University of California, San Francisco, California 94143, USA
    Curr Opin HIV AIDS 4:52-6. 2009
  4. doi request reprint The epidemiology of anal human papillomavirus and related neoplasia
    Joel M Palefsky
    Division of Infectious Disease, Department of Medicine, University of California, Box 0126, Room M1203, San Francisco, CA 94143, USA
    Obstet Gynecol Clin North Am 36:187-200. 2009
  5. ncbi request reprint Chapter 16: HPV vaccines in immunocompromised women and men
    Joel M Palefsky
    Department of Medicine, University of California San Francisco, 505 Parnassus Avenue, San Francisco, CA 94143 0126, USA
    Vaccine 24:S3/140-6. 2006
  6. pmc Anal cancer prevention in HIV-positive men and women
    Joel M Palefsky
    Department of Medicine, University of California, San Francisco, San Francisco, California 94143, USA
    Curr Opin Oncol 21:433-8. 2009
  7. pmc Human papillomavirus-related disease in men: not just a women's issue
    Joel M Palefsky
    Department of Medicine, University of California, San Francisco, California 94143, USA
    J Adolesc Health 46:S12-9. 2010
  8. doi request reprint HPV vaccine against anal HPV infection and anal intraepithelial neoplasia
    Joel M Palefsky
    Department of Medicine, University of California at San Francisco, Box 0654, San Francisco, CA 94143, USA
    N Engl J Med 365:1576-85. 2011
  9. ncbi request reprint Human papillomavirus and anal neoplasia
    Joel Palefsky
    University of California, San Francisco, 505 Parnassus Avenue, Room M1203, Box 0126, San Francisco, CA 94143, USA
    Curr HIV/AIDS Rep 5:78-85. 2008
  10. ncbi request reprint Human papillomavirus anogenital disease in HIV-infected individuals
    Peter V Chin-Hong
    Department of Medicine, University of California, San Francisco 94143 0654, USA
    Dermatol Ther 18:67-76. 2005

Detail Information

Publications82

  1. ncbi request reprint Human papillomavirus-related tumors in HIV
    Joel Palefsky
    Department of Medicine, University of California, San Francisco, California 94143, USA
    Curr Opin Oncol 18:463-8. 2006
    ....
  2. pmc HPV infection in men
    Joel M Palefsky
    Department of Medicine, University of California, San Francisco, CA 94143, USA
    Dis Markers 23:261-72. 2007
    ..The impact of HPV vaccination in women on male anogenital HPV infection will also need to be assessed...
  3. pmc Human papillomavirus-related disease in people with HIV
    Joel Palefsky
    University of California, San Francisco, California 94143, USA
    Curr Opin HIV AIDS 4:52-6. 2009
    ....
  4. doi request reprint The epidemiology of anal human papillomavirus and related neoplasia
    Joel M Palefsky
    Division of Infectious Disease, Department of Medicine, University of California, Box 0126, Room M1203, San Francisco, CA 94143, USA
    Obstet Gynecol Clin North Am 36:187-200. 2009
    ..This article describes the epidemiology of anal HPV infection, anal intraepithelial neoplasia, and anal cancer among men and women, as well as current efforts to prevent anal cancers...
  5. ncbi request reprint Chapter 16: HPV vaccines in immunocompromised women and men
    Joel M Palefsky
    Department of Medicine, University of California San Francisco, 505 Parnassus Avenue, San Francisco, CA 94143 0126, USA
    Vaccine 24:S3/140-6. 2006
    ..Clinical studies are needed to determine HPV vaccine safety and effectiveness in different populations of immunocompromised women and men...
  6. pmc Anal cancer prevention in HIV-positive men and women
    Joel M Palefsky
    Department of Medicine, University of California, San Francisco, San Francisco, California 94143, USA
    Curr Opin Oncol 21:433-8. 2009
    ..This review discusses the issues around screening to prevent anal cancer...
  7. pmc Human papillomavirus-related disease in men: not just a women's issue
    Joel M Palefsky
    Department of Medicine, University of California, San Francisco, California 94143, USA
    J Adolesc Health 46:S12-9. 2010
    ....
  8. doi request reprint HPV vaccine against anal HPV infection and anal intraepithelial neoplasia
    Joel M Palefsky
    Department of Medicine, University of California at San Francisco, Box 0654, San Francisco, CA 94143, USA
    N Engl J Med 365:1576-85. 2011
    ..We studied the safety and efficacy of quadrivalent HPV vaccine (qHPV) against anal intraepithelial neoplasia associated with HPV-6, 11, 16, or 18 infection in men who have sex with men...
  9. ncbi request reprint Human papillomavirus and anal neoplasia
    Joel Palefsky
    University of California, San Francisco, 505 Parnassus Avenue, Room M1203, Box 0126, San Francisco, CA 94143, USA
    Curr HIV/AIDS Rep 5:78-85. 2008
    ....
  10. ncbi request reprint Human papillomavirus anogenital disease in HIV-infected individuals
    Peter V Chin-Hong
    Department of Medicine, University of California, San Francisco 94143 0654, USA
    Dermatol Ther 18:67-76. 2005
    ..Prophylactic and therapeutic HPV vaccines are promising as future interventions for disease control in at-risk populations such as HIV-infected women and men...
  11. pmc Cervical human papillomavirus infection among young women engaged in sex work in Phnom Penh, Cambodia: prevalence, genotypes, risk factors and association with HIV infection
    Marie Claude Couture
    University of California San Francisco, Global Health Sciences, 50 Beale Street, Suite 1200, San Francisco, CA 94105, USA
    BMC Infect Dis 12:166. 2012
    ..We examine the prevalence and genotypes of cervical HPV, as well as the associated risk factors among young women engaged in sex work in Phnom Penh, Cambodia...
  12. ncbi request reprint Transcriptional profiling of dysplastic lesions in K14-HPV16 transgenic mice using laser microdissection
    Neerja Sethi
    Department of Medicine, University of California, San Francisco, California, USA
    FASEB J 18:1243-5. 2004
    ..We showed that the transgenic mice express correctly spliced E2 transcripts and are suitable as a preclinical model to test a therapeutic strategy using transcriptional regulation by the E2 protein...
  13. pmc The Epstein-Barr virus BMRF-2 protein facilitates virus attachment to oral epithelial cells
    Jianqiao Xiao
    Department of Medicine, University of California, San Francisco, CA 94143 0654, USA
    Virology 370:430-42. 2008
    ..These data are consistent with our previous observation that interactions between EBV BMRF-2 and integrins are critical for infection of oral epithelial cells with EBV...
  14. ncbi request reprint Self-collected versus clinician-collected anal cytology specimens to diagnose anal intraepithelial neoplasia in HIV-positive men
    Ross D Cranston
    Department of Medicine, University of California at San Francisco, 94143, USA
    J Acquir Immune Defic Syndr 36:915-20. 2004
    ..Anal intraepithelial neoplasia (AIN) is common in men who have sex with men (MSM) and may be diagnosed by anal cytology screening...
  15. pmc Highly tissue substructure-specific effects of human papilloma virus in mucosa of HIV-infected patients revealed by laser-dissection microscopy-assisted gene expression profiling
    Nicole Baumgarth
    Center for Comparative Medicine, University of California, Davis, CA, USA
    Am J Pathol 165:707-18. 2004
    ..Because of its large dynamic measurement range it could also become a method of choice to confirm and better quantify results obtained by microarray analysis...
  16. pmc Updating the natural history of human papillomavirus and anogenital cancers
    Anna Barbara Moscicki
    Division of Adolescent Medicine, Department of Pediatrics, University of California, San Francisco, San Francisco, CA, USA
    Vaccine 30:F24-33. 2012
    ..This article forms part of a special supplement entitled "Comprehensive Control of HPV Infections and Related Diseases" Vaccine Volume 30, Supplement 5, 2012...
  17. ncbi request reprint Human papillomavirus infection in HIV-infected persons
    Joel Palefsky
    University of California San Francisco, San Francisco, CA, USA
    Top HIV Med 15:130-3. 2007
    ..This article summarizes a presentation on HPV infection in HIV-infected patients made by Joel Palefsky, MD, at an International AIDS Society-USA Continuing Medical Education course in Chicago in May 2007...
  18. doi request reprint Cervical human papillomavirus incidence and persistence in a cohort of HIV-negative women in Zimbabwe
    Emily Fukuchi
    Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California San Francisco, 2340 Sutter Street, San Francisco, CA 94143, USA
    Sex Transm Dis 36:305-11. 2009
    ..Little is known about the distribution of HPV types, independent risk factors of incidence and persistence, and patterns of persistence in sub-Saharan Africa...
  19. pmc Type-specific cervico-vaginal human papillomavirus infection increases risk of HIV acquisition independent of other sexually transmitted infections
    Karen K Smith-McCune
    Department of Obstetrics, Gynecology and Reproductive Sciences, University of California San Francisco, San Francisco, California, United States of America
    PLoS ONE 5:e10094. 2010
    ..The objective of this study was to determine whether cervico-vaginal HPV infection increases the risk of HIV acquisition in women independent of other common STIs...
  20. ncbi request reprint Age-related prevalence of anal cancer precursors in homosexual men: the EXPLORE study
    Peter V Chin-Hong
    Department of Medicine, University of California San Francisco, CA 94143 0654, USA
    J Natl Cancer Inst 97:896-905. 2005
    ..The prevalence of cervical cancer precursor lesions peaks at around 30 years of age. The age-related prevalence of ASILs in HIV-negative MSM is unknown...
  21. ncbi request reprint Anal intraepithelial neoplasia in the highly active antiretroviral therapy era among HIV-positive men who have sex with men
    Joel M Palefsky
    Department of Medicine, University of California, San Francisco, California 94143, USA
    AIDS 19:1407-14. 2005
    ..We characterized the prevalence of AIN among HIV-positive MSM and examined the association between AIN and various factors including use of HAART...
  22. ncbi request reprint A trial of SGN-00101 (HspE7) to treat high-grade anal intraepithelial neoplasia in HIV-positive individuals
    Joel M Palefsky
    Department of Medicine, University of California San Francisco, 505 Parnassus Avenue, San Francisco, CA 94143, USA
    AIDS 20:1151-5. 2006
    ....
  23. ncbi request reprint Molecular cytogenetic characterization of human papillomavirus16-transformed foreskin keratinocyte cell line 16-MT
    Eva M McGhee
    Department of Community Health Systems, University of California, San Francisco, Room N505, Box 0608 San Francisco, CA 94143 0608, USA
    Cancer Genet Cytogenet 168:36-43. 2006
    ..Furthermore, these data represent the first full characterization of the HPV-positive cell line 16-MT...
  24. doi request reprint Effect of diaphragm and lubricant gel provision on human papillomavirus infection among women provided with condoms: a randomized controlled trial
    George F Sawaya
    Department of Obstetrics, Gynecology and Reproductive Sciences, University of California, San Francisco, Helen Diller Family Comprehensive Cancer Center, San Francisco, California 94118, USA
    Obstet Gynecol 112:990-7. 2008
    ..To estimate the effect of providing women with a latex diaphragm, lubricant gel, and male condoms (intervention) compared with condoms alone (control) on human papillomavirus (HPV) incidence and clearance...
  25. pmc Anal intraepithelial neoplasia in a multisite study of HIV-infected and high-risk HIV-uninfected women
    Nancy A Hessol
    Department of Clinical Pharmacy, University of California, San Francisco, California 94122, USA
    AIDS 23:59-70. 2009
    ..To study anal intraepithelial neoplasia and its associations with anal and cervical human papillomavirus (HPV), cervical neoplasia, host immune status, and demographic and behavioral risk factors in women with and at risk for HIV infection...
  26. doi request reprint Performance characteristics of anal cytology and human papillomavirus testing in patients with high-resolution anoscopy-guided biopsy of high-grade anal intraepithelial neoplasia
    J Michael Berry
    Department of Medicine, University of California San Francisco, San Francisco, California, USA
    Dis Colon Rectum 52:239-47. 2009
    ..High-resolution anoscopy with biopsy was used as the standard for detecting high-grade anal neoplasia and was compared to detection of high-grade anal neoplasia by anal cytology, human papillomavirus testing, or the combination...
  27. pmc EBV BMRF-2 facilitates cell-to-cell spread of virus within polarized oral epithelial cells
    Jianqiao Xiao
    Department of Medicine, University of California, San Francisco, USA
    Virology 388:335-43. 2009
    ..These data show that BMRF-2 may play an important role in promoting the spread of EBV progeny virions through lateral membranes of oral epithelial cells...
  28. doi request reprint Anal human papillomavirus infection is associated with HIV acquisition in men who have sex with men
    Peter V Chin-Hong
    Department of Medicine, University of California, San Francisco, San Francisco, California 94143, USA
    AIDS 23:1135-42. 2009
    ..Our aim was to determine the association between anal HPV infection and HIV acquisition...
  29. ncbi request reprint Effect of Replens gel used with a diaphragm on tests for human papillomavirus and other lower genital tract infections
    Karen K Smith-McCune
    Department of Obstetrics, Gynecology and Reproductive Sciences, University of California San Francisco, San Francisco, CA 94143 0128, USA
    J Low Genit Tract Dis 10:213-8. 2006
    ..We hypothesized that Replens gel used with a diaphragm would neither inhibit human papillomavirus (HPV) detection in cervical samples and chlamydia (CT) and gonorrhea (GC) detection in urine samples, nor affect cervical cytology quality...
  30. pmc Epstein-Barr virus (EBV)-infected monocytes facilitate dissemination of EBV within the oral mucosal epithelium
    Sharof Tugizov
    Department of Medicine, University of California San Francisco, 513 Parnassus Ave, San Francisco, CA 94143 0512, USA
    J Virol 81:5484-96. 2007
    ....
  31. ncbi request reprint Comparison of patient- and clinician-collected anal cytology samples to screen for human papillomavirus-associated anal intraepithelial neoplasia in men who have sex with men
    Peter V Chin-Hong
    University of California, San Francisco, Box 0654, 513 Parnassus Avenue, Room S 380, San Francisco, CA 94143 0654, USA
    Ann Intern Med 149:300-6. 2008
    ..Cytology screening can detect the anal cancer precursor, anal intraepithelial neoplasia (AIN). Little is known about self-collected samples for AIN screening, and few community-based AIN estimates exist...
  32. ncbi request reprint Kidney and liver transplantation in human immunodeficiency virus-infected patients: a pilot safety and efficacy study
    Peter G Stock
    Department of Surgery, Division of Transplantation, University of California, San Francisco, California 94143 0780, USA
    Transplantation 76:370-5. 2003
    ....
  33. ncbi request reprint Cervical human papillomavirus infection and cervical intraepithelial neoplasia in women positive for human immunodeficiency virus in the era of highly active antiretroviral therapy
    Joel M Palefsky
    Department of Medicine, University of California, San Francisco, USA
    Curr Opin Oncol 15:382-8. 2003
    ..The purpose of this review is to summarize recent studies of cervical HPV infection and CIN in HIV-positive women and to describe the effect of highly active antiretroviral therapy (HAART) on the course of CIN...
  34. ncbi request reprint A review of human papillomavirus vaccines: from basic science to clinical trials
    J Michael Berry
    University of California, San Francisco, Box 0512, 521 Parnassus Ave, San Francisco, CA 94143 0512, USA
    Front Biosci 8:s333-45. 2003
    ..All of the vaccines appear to be safe, well tolerated, and preliminary data indicates that most are clinically effective. Multiple trials are in progress and more mature data are expected within the next few years...
  35. ncbi request reprint Anal cancer and its precursors in HIV-positive patients: perspectives and management
    J Michael Berry
    General Clinical Research Center, University of California San Francisco School of Medicine, 505 Parnassus Avenue, Room M1203, Box 0126, San Francisco, CA 94143, USA
    Surg Oncol Clin N Am 13:355-73. 2004
    ....
  36. ncbi request reprint Epstein-Barr virus infection of polarized tongue and nasopharyngeal epithelial cells
    Sharof M Tugizov
    Department of Stomatology, School of Dentistry, University of California San Francisco, San Francisco, California, USA
    Nat Med 9:307-14. 2003
    ..Release of progeny virions from polarized cells occurs from both their apical and basolateral membranes. These data indicate that multiple approaches to prevention of epithelial infection with EBV will be necessary...
  37. ncbi request reprint Natural history and clinical management of anal human papillomavirus disease in men and women infected with human immunodeficiency virus
    Peter V Chin-Hong
    Division of Infectious Diseases, Department of Medicine, University of California, San Francisco, CA 94143 0512, USA
    Clin Infect Dis 35:1127-34. 2002
    ..Treatment for AIN remains challenging, but AIN is easier to treat when the lesions are small, and it is likely that a screening program would identify affected individuals at an earlier stage of disease...
  38. pmc Time course of humoral and cell-mediated immune responses to human papillomavirus type 16 in infected women
    Mayumi Nakagawa
    Departments of Laboratory Medicine, Schools of Medicine and Dentistry, University of California at San Francisco, San Francisco, California 94143 0134, USA
    Clin Diagn Lab Immunol 9:877-82. 2002
    ..Overall, seven of eight subjects (88%) had detectable HPV-16 E6 and/or E7 CTL responses and seven of eight women (88%) had detectable HPV-16 VLP antibody responses...
  39. ncbi request reprint Age-Specific prevalence of anal human papillomavirus infection in HIV-negative sexually active men who have sex with men: the EXPLORE study
    Peter V Chin-Hong
    Department of Medicine, University of California at San Francisco, California 94143 0654, USA
    J Infect Dis 190:2070-6. 2004
    ..In women, cervical HPV infection peaks early and decreases after the age of 30. Little is known about the age-specific prevalence of anal HPV infection in human immunodeficiency virus (HIV)-negative MSM...
  40. ncbi request reprint Encapsulated plasmid DNA treatment for human papillomavirus 16-associated anal dysplasia: a Phase I study of ZYC101
    Barbara Klencke
    Department of Medicine, Division of Medical Oncology, University of California at San Francisco, 94115, USA
    Clin Cancer Res 8:1028-37. 2002
    ..These results support the continued investigation of a therapeutic vaccination strategy for anal dysplasia...
  41. ncbi request reprint Evidence for trafficking of Epstein-Barr virus strains between hairy leukoplakia and peripheral blood lymphocytes
    Joel M Palefsky
    Department of Stomatology, School of Dentistry, and the Oral AIDS Center, University of California San Francisco, 505 Parnassus Avenue, San Francisco, CA 94143 0126, USA
    J Gen Virol 83:317-21. 2002
    ..Our data are consistent with active trafficking of EBV between these two compartments...
  42. pmc HIV is inactivated after transepithelial migration via adult oral epithelial cells but not fetal epithelial cells
    Sharof M Tugizov
    Department of Medicine, University of California San Francisco, 513 Parnassus Ave, San Francisco, CA 94143 0512, USA
    Virology 409:211-22. 2011
    ..Inactivation of innate proteins in adult oral keratinocytes restored HIV infectivity. These data suggest that high-level innate protein expression may contribute to the resistance of the adult oral epithelium to HIV transmission...
  43. pmc EBV-positive human sera contain antibodies against the EBV BMRF-2 protein
    Jianqiao Xiao
    Department of Medicine, University of California, San Francisco, CA 94143 0654, USA
    Virology 393:151-9. 2009
    ..These data indicate that RGD motif of BMRF-2 is part of an immunodominant antigenic determinant within the extracellular domain of BMRF-2 that may contribute to EBV neutralization during EBV reactivation...
  44. ncbi request reprint Surgical treatment of high-grade anal squamous intraepithelial lesions: a prospective study
    George J Chang
    Department of Surgery, University of California at San Francisco, San Francisco, California, USA
    Dis Colon Rectum 45:453-8. 2002
    ..We report the first prospective study of high-resolution anoscopy-directed surgical treatment of high-grade squamous intraepithelial lesions...
  45. ncbi request reprint Increased risk of high-grade anal neoplasia associated with a human papillomavirus type 16 E6 sequence variant
    Maria M Da Costa
    Department of Laboratory Medicine, University of California, San Francisco, San Francisco, CA 94143, USA
    J Infect Dis 185:1229-37. 2002
    ..4; 95% confidence interval, 1.1-10), after controlling for HIV status. These data provide further evidence for HPV strain variation as a factor in determining the natural history of anogenital neoplasia...
  46. ncbi request reprint Anal cancer: an HIV-associated cancer
    Barbara J Klencke
    Division of Hematology and Oncology, University of California at San Francisco, 505 Parnassus Avenue, San Francisco, CA 94143, USA
    Hematol Oncol Clin North Am 17:859-72. 2003
    ..Large, prospective studies will be required before solid conclusions about the impact of various factors on anal cancer prognosis and outcome can be drawn...
  47. ncbi request reprint Characterization of the Epstein-Barr virus glycoprotein BMRF-2
    Jianqiao Xiao
    Department of Medicine, University of California, San Francisco, USA
    Virology 359:382-96. 2007
    ..We show that BMRF-2 is a ligand for beta1, alpha5, alpha3, and alphav integrins and our data are consistent with a role for BMRF-2 in viral lytic infection...
  48. pmc Inhibition of human papillomavirus type 16 E7 phosphorylation by the S100 MRP-8/14 protein complex
    Sharof Tugizov
    Department of Medicine, University of California, San Francisco, 513 Parnassus Ave, San Francisco, CA 94143, USA
    J Virol 79:1099-112. 2005
    ..Together these results suggests that the MRP-8/14 protein complex in HPV-infected epithelial cells may play an important role in regulation of CKII-mediated E7 phosphorylation and inhibition of its oncogenic activity...
  49. ncbi request reprint High-resolution analysis of genomic alterations and human papillomavirus integration in anal intraepithelial neoplasia
    S Eric Gagne
    Comprehensive Cancer Center, Department of Laboratory Medicine, University of California, San Francisco, San Francisco, CA 94143 0126, USA
    J Acquir Immune Defic Syndr 40:182-9. 2005
    ..Our data suggest that there may be several oncogenes in this region that are coactivated to contribute to progression to high-grade AIN...
  50. ncbi request reprint Human papilloma virus type 69 identified in a clinically aggressive plantar verruca from an HIV-positive patient
    Jeffrey M Whitaker
    California College of Podiatric Medicine, San Francisco, CA 94609, USA
    J Am Podiatr Med Assoc 99:8-12. 2009
    ..Although cutaneous verrucae are typically caused by HPV-1, HPV-2, and HPV-4, infection with HIV may predispose an individual to infection with an unusual HPV type...
  51. doi request reprint 48. Cidofovir treatment prevents invasion of invasive HPV-16-positive anal keratinocytes
    Erin Isaacson Wechsler
    University of California, San Francisco, CA, USA
    Sex Health 10:593. 2013
    ..Cidofovir could potentially be useful as an adjuvant treatment for invasive anal cancers, and its mechanism of action in inhibiting cellular invasion requires further study. ..
  52. doi request reprint 32. HPV type and strain variant concordance between anal cancers and their preceding high-grade squamous intraepithelial lesions
    Joel Palefsky
    University of California, San Francisco, CA, USA
    Sex Health 10:585-6. 2013
    ..Two pairs contained the Eur-350G variant alone. Conclusions: Concordance of both the HPV type and strain variant in anal cancers and their site-matched preceding HSIL further supports the role of anal HSIL as an anal cancer precursor. ..
  53. pmc Human papillomavirus infection in women in Puerto Rico: agreement between physician-collected and self-collected anogenital specimens
    Ana Patricia Ortiz
    Cancer Control and Population Sciences Program, University of Puerto Rico Comprehensive Cancer Center and Biostatistics and Epidemiology Department, Graduate School of Public Health, University of Puerto Rico, PMB 711, Ave de Diego89, Suite 105, San Juan, PR 00927 6346
    J Low Genit Tract Dis 17:210-7. 2013
    ....
  54. ncbi request reprint Treatment of human papillomavirus (HPV) type 16-infected cells using herpes simplex virus type 1 thymidine kinase-mediated gene therapy transcriptionally regulated by the HPV E2 protein
    Neerja Sethi
    Department of Medicine and Department of Stomatology, University of California, San Francisco, San Francisco, CA 94143, USA
    Hum Gene Ther 14:45-57. 2003
    ..These results suggest that direct gene transfer of the HSV-1 TK gene into HPV-16-infected cells expressing E2 protein, accompanied by treatment with either GCV or ACV, may be a clinically feasible therapeutic strategy...
  55. doi request reprint Addition of a single E2 binding site to the human papillomavirus (HPV) type 16 long control region enhances killing of HPV positive cells via HPV E2 protein-regulated herpes simplex virus type 1 thymidine kinase-mediated suicide gene therapy
    Rachna Sharma
    Department of Medicine, University of California San Francisco, San Francisco, CA 94143, USA
    Hum Gene Ther 21:843-54. 2010
    ..As HPV-infected patients also exhibit variable E2 expression across lesions and within a lesion, this approach may potentiate the clinical utility of the herpes simplex virus type 1 TK/ganciclovir therapeutic approach...
  56. ncbi request reprint Variants of human papillomaviruses 16 and 18 and their natural history in human immunodeficiency virus-positive women
    Nicolas F Schlecht
    Albert Einstein College of Medicine, Department of Epidemiology and Population Health, 1300 Morris Park Avenue, Bronx, NY 10461, USA
    J Gen Virol 86:2709-20. 2005
    ..If non-European variants are more oncogenic, the effect may involve a late stage in cervical tumorigenesis...
  57. ncbi request reprint Incidence of cervical squamous intraepithelial lesions associated with HIV serostatus, CD4 cell counts, and human papillomavirus test results
    Tiffany G Harris
    Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    JAMA 293:1471-6. 2005
    ....
  58. ncbi request reprint Anal cancer in HIV infection: to screen or not to screen?
    Sue Goldie
    AIDS Clin Care 16:53-5, 57. 2004
  59. ncbi request reprint Effects of bacterial vaginosis and other genital infections on the natural history of human papillomavirus infection in HIV-1-infected and high-risk HIV-1-uninfected women
    D Heather Watts
    National Institute of Child Health and Human Development, NIH, Bethesda, Maryland 20892 7510, USA
    J Infect Dis 191:1129-39. 2005
    ..Whether the natural history of human papillomavirus (HPV) infection is affected by bacterial vaginosis (BV) or Trichomonas vaginalis (TV) infection has not been adequately investigated in prospective studies...
  60. ncbi request reprint Screening HIV-infected individuals for anal cancer precursor lesions: a systematic review
    Elizabeth Y Chiao
    Baylor College of Medicine, Houston Center for Quality of Care and Utilization Studies, Health Services Research and Development Service, Michael E DeBakey Veterans Affairs Medical Center, TX, USA
    Clin Infect Dis 43:223-33. 2006
    ..This review identifies important areas for further study before routine anal Pap smear screening can be recommended...
  61. ncbi request reprint Advances in prevention of cervical cancer and other human papillomavirus-related diseases
    Ian H Frazer
    University of Queensland, Center for Immunology and Cancer Research, Brisbane, QLD 4072, Australia
    Pediatr Infect Dis J 25:S65-81, quiz S82. 2006
  62. ncbi request reprint Natural history and possible reactivation of human papillomavirus in human immunodeficiency virus-positive women
    Howard D Strickler
    Department of Epidemiology and Population Health, Albert Einstein College of Medicine, 1300 Morris Park Ave, Belfer 1308, Bronx, NY 10461, USA
    J Natl Cancer Inst 97:577-86. 2005
    ....
  63. ncbi request reprint Activity of HspE7, a novel immunotherapy, in patients with anogenital warts
    Stephen E Goldstone
    Mount Sinai School of Medicine, New York, New York, USA
    Dis Colon Rectum 45:502-7. 2002
    ..Treatment of squamous intraepithelial lesions to prevent cancer often requires extensive surgery. We tested a human papillomavirus-specific immunotherapy, HspE7, as a potential alternative...
  64. ncbi request reprint Chlamydia trachomatis, herpes simplex virus 2, and human T-cell lymphotrophic virus type 1 are not associated with grade of cervical neoplasia in Jamaican colposcopy patients
    Philip E Castle
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland 20892, USA
    Sex Transm Dis 30:575-80. 2003
    ..A few recent studies have suggested that other sexually transmitted infections may increase the likelihood of a human papillomavirus (HPV) infection progressing to high-grade cervical neoplasia and cancer...
  65. ncbi request reprint Effect of antiretroviral therapy on the incidence of genital warts and vulvar neoplasia among women with the human immunodeficiency virus
    L Stewart Massad
    Southern Illinois University School of Medicine, Springfield, Illinois 62794 9640, USA
    Am J Obstet Gynecol 190:1241-8. 2004
    ..The purpose of this study was to determine the incidence and predictors of genital warts and vulvar intraepithelial neoplasia among women with the human immunodeficiency virus...
  66. ncbi request reprint High prevalence of anal human papillomavirus infection and anal cancer precursors among HIV-infected persons in the absence of anal intercourse
    Christophe Piketty
    INSERM U 430 and Hôpital Européen Georges Pompidou, 20 rue Leblanc, 75015 Paris, France
    Ann Intern Med 138:453-9. 2003
    ..Anal HPV infection and anal SIL are common in HIV-positive men who have sex with men; receptive anal intercourse is presumed to be the mode of acquisition of HPV...
  67. ncbi request reprint Association of cutaneous anergy with human papillomavirus and cervical neoplasia in HIV-seropositive and seronegative women
    Tiffany G Harris
    Albert Einstein College of Medicine, Bronx, New York 10461, USA
    AIDS 21:1933-41. 2007
    ..This study assessed the relationship of anergy test results with cervical infection by human papillomavirus (HPV) and cervical neoplasia in HIV-seropositive and seronegative women...
  68. ncbi request reprint High resolution anoscopy in the planned staged treatment of anal squamous intraepithelial lesions in HIV-negative patients
    Carlos E Pineda
    Department of Surgery, Stanford University School of Medicine, 300 Pasteur Drive, H3680F, Stanford, CA 94305 5655, USA
    J Gastrointest Surg 11:1410-5; discussion 1415-6. 2007
    ..Morbidity is minimal, and our progression to cancer rate is low (2.4%)...
  69. ncbi request reprint The impact of HIV antiviral therapy on human papillomavirus (HPV) infections and HPV-related diseases
    Isabelle Heard
    Institut National de la Santé et de la Recherche Médicale U430 and Unite d Immunologie Clinique, Hopital Europeen G Pompidou, Paris, France
    Antivir Ther 9:13-22. 2004
    ..However, data on the impact of HAART on HPV disease are sparse and mixed results have been reported...
  70. ncbi request reprint Infrared coagulator treatment of high-grade anal dysplasia in HIV-infected individuals: an AIDS malignancy consortium pilot study
    Elizabeth A Stier
    Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    J Acquir Immune Defic Syndr 47:56-61. 2008
    ..To evaluate prospectively the safety of the infrared coagulator (IRC) as a treatment for anal high-grade squamous intraepithelial lesions (HSILs) in HIV-infected individuals and to seek preliminary evidence for efficacy...
  71. doi request reprint Insulin-like growth factor axis and oncogenic human papillomavirus natural history
    Tiffany G Harris
    Department of Epidemiology and Population Health, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA
    Cancer Epidemiol Biomarkers Prev 17:245-8. 2008
    ..07; 95% CI, 0.01-0.66). These prospective data provide initial evidence that the IGF axis may influence the natural history of oncogenic HPV...
  72. doi request reprint High-resolution anoscopy targeted surgical destruction of anal high-grade squamous intraepithelial lesions: a ten-year experience
    Carlos E Pineda
    Department of General Surgery, Stanford University School of Medicine, Stanford, California, USA
    Dis Colon Rectum 51:829-35; discussion 835-7. 2008
    ....
  73. pmc The relationship between cocaine use and human papillomavirus infections in HIV-seropositive and HIV-seronegative women
    Howard Minkoff
    Department of Obstetrics and Gynecology at Maimonides Medical Center and SUNY Downstate, NY 11219, USA
    Infect Dis Obstet Gynecol 2008:587082. 2008
    ..Since both cocaine use and HPV infection are common among HIV-positive women, we sought to determine whether use of cocaine and/or crack influences the natural history of HPV among women with or at high risk of HIV...
  74. ncbi request reprint Relationship between smoking and human papillomavirus infections in HIV-infected and -uninfected women
    Howard Minkoff
    Department of Obstetrics and Gynecology, Maimonides Medical Center, Brooklyn, New York, USA
    J Infect Dis 189:1821-8. 2004
    ..Among HIV-infected women, smoking is associated with a significantly higher prevalence and incidence of HPV infection. Smoking during HIV infection may alter the natural history of HPV infection and increase the risk of cervical disease...
  75. doi request reprint HPV types present in invasive cervical cancers of HIV-seropositive women
    Howard D Strickler
    Int J Cancer 123:1224-5. 2008
  76. ncbi request reprint Incidence of anal cytological abnormalities in a cohort of human immunodeficiency virus-infected women
    Amanda J Durante
    Connecticut Emerging Infections Program, Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, Connecticut 06510, USA
    Cancer Epidemiol Biomarkers Prev 12:638-42. 2003
    ..Continued research on the association between smoking and the development of squamous intraepithelial lesions in HIV-infected women is warranted...
  77. ncbi request reprint Human papillomavirus type 16 and immune status in human immunodeficiency virus-seropositive women
    Howard D Strickler
    Department of Epidemiology and Social Medicine, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    J Natl Cancer Inst 95:1062-71. 2003
    ..To address this issue, we examined HPV test results from repeated study visits in the WIHS and from an independent study, the HIV Epidemiology Research Study (HERS)...
  78. pmc Colorectal papillomavirus infection in patients with colorectal cancer
    Sohrab Bodaghi
    HIV and AIDS Malignancy Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland 20892, USA
    Clin Cancer Res 11:2862-7. 2005
    ..The samples were processed in a blinded fashion for nested PCR and in situ PCR detection of HPV DNAs. The PCR products were gel-purified and sequenced for HPV genotyping...
  79. ncbi request reprint High prevalence of anal squamous intraepithelial lesions in HIV-positive men despite the use of highly active antiretroviral therapy
    Christophe Piketty
    Department of Immunology, INSERM U 430 and Université Pierre et Marie Curie, Hopital Europeen Georges Pompidou, Paris, France
    Sex Transm Dis 31:96-9. 2004
    ..GOAL The goal of this study was to evaluate the prevalence of anal HPV infection and SIL inpatients under HAART...
  80. ncbi request reprint Six-month natural history of oral versus cervical human papillomavirus infection
    Carole Fakhry
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21231, USA
    Int J Cancer 121:143-50. 2007
    ..001). Our study not only demonstrates that it is feasible to study the natural history of oral HPV infection with oral rinse sampling, but also indicates that oral and cervical HPV natural history may differ...
  81. ncbi request reprint Role of E-cadherin in the induction of apoptosis of HPV16-positive CaSki cervical cancer cells during multicellular tumor spheroid formation
    Takeshi Haga
    Department of Veterinary Microbiology, University of Miyazaki, 1 1 Gakuen Kibanadai Nishi, Miyazaki, Japan
    Apoptosis 13:97-108. 2008
    ....