Grier P Page

Summary

Affiliation: University of Alabama at Birmingham
Country: USA

Publications

  1. pmc Breast fibroblasts modulate epithelial cell proliferation in three-dimensional in vitro co-culture
    Andrea Sadlonova
    Department of Pathology, The University of Alabama at Birmingham, Alabama, USA
    Breast Cancer Res 7:R46-59. 2005
  2. pmc Detecting epistatic interactions contributing to human gene expression using the CEPH family data
    Hua Li
    Bioinformatics Center, Stowers Institute for Medical Research, 1000 East 50th Street, Kansas City, Missouri 64110, USA
    BMC Proc 1:S67. 2007
  3. pmc Reproducible clusters from microarray research: whither?
    Nikhil R Garge
    Medical College of Georgia, 1120 15th Street, Ca4100, Augusta, GA 30912, USA, Email
    BMC Bioinformatics 6:S10. 2005
  4. ncbi request reprint A design and statistical perspective on microarray gene expression studies in nutrition: the need for playful creativity and scientific hard-mindedness
    Grier P Page
    Department of Biostatistics, Section on Statistical Genetics, University of Alabama at Birmingham, Birmingham, Alabama 35294 0022, USA
    Nutrition 19:997-1000. 2003
  5. pmc The PowerAtlas: a power and sample size atlas for microarray experimental design and research
    Grier P Page
    Department of Biostatistics, University of Alabama, Birmingham, AL, USA
    BMC Bioinformatics 7:84. 2006
  6. pmc A proposed metric for assessing the measurement quality of individual microarrays
    Kyoungmi Kim
    Department of Biostatistics, University of Alabama, Birmingham, Alabama, USA
    BMC Bioinformatics 7:35. 2006
  7. ncbi request reprint Optimal allocation of replicates for measurement evaluation studies
    Stanislav O Zakharkin
    Department of Biostatistics, University of Alabama at Birmingham, Birmingham, AL 35294 0022, USA
    Genomics Proteomics Bioinformatics 4:196-202. 2006
  8. pmc Sources of variation in Affymetrix microarray experiments
    Stanislav O Zakharkin
    University of Alabama, Birmingham, Alabama, USA
    BMC Bioinformatics 6:214. 2005
  9. ncbi request reprint Microarray analysis
    Grier P Page
    Department of Biostatistics, University of Alabama at Birmingham, Hoover, AL, USA
    Methods Mol Biol 404:409-30. 2007
  10. ncbi request reprint Microarray data analysis: from disarray to consolidation and consensus
    David B Allison
    Section on Statistical Genetics, Department of Biostatistics, Ryals Public Health Building, 1665 University Avenue, University of Alabama at Birmingham, Alabama 35294 0022, USA
    Nat Rev Genet 7:55-65. 2006

Detail Information

Publications41

  1. pmc Breast fibroblasts modulate epithelial cell proliferation in three-dimensional in vitro co-culture
    Andrea Sadlonova
    Department of Pathology, The University of Alabama at Birmingham, Alabama, USA
    Breast Cancer Res 7:R46-59. 2005
    ..To this end, the effect of CAF and normal breast-associated fibroblasts (NAF) on the growth of epithelial cells representative of pre-neoplastic breast disease was assessed...
  2. pmc Detecting epistatic interactions contributing to human gene expression using the CEPH family data
    Hua Li
    Bioinformatics Center, Stowers Institute for Medical Research, 1000 East 50th Street, Kansas City, Missouri 64110, USA
    BMC Proc 1:S67. 2007
    ..We evaluated the power of the method by simulation studies and applied this method to the analysis of the Centre d'Etude du Polymorphisme Humain family gene expression data provided by Genetics Analysis Workshop 15 (GAW15)...
  3. pmc Reproducible clusters from microarray research: whither?
    Nikhil R Garge
    Medical College of Georgia, 1120 15th Street, Ca4100, Augusta, GA 30912, USA, Email
    BMC Bioinformatics 6:S10. 2005
    ..We used this approach to determine the performance of commonly used clustering algorithms and the degree of replicability achieved using several microarray datasets...
  4. ncbi request reprint A design and statistical perspective on microarray gene expression studies in nutrition: the need for playful creativity and scientific hard-mindedness
    Grier P Page
    Department of Biostatistics, Section on Statistical Genetics, University of Alabama at Birmingham, Birmingham, Alabama 35294 0022, USA
    Nutrition 19:997-1000. 2003
    ....
  5. pmc The PowerAtlas: a power and sample size atlas for microarray experimental design and research
    Grier P Page
    Department of Biostatistics, University of Alabama, Birmingham, AL, USA
    BMC Bioinformatics 7:84. 2006
    ..In addition, investigators frequently do not have pilot data to estimate the sample sizes required for microarray studies...
  6. pmc A proposed metric for assessing the measurement quality of individual microarrays
    Kyoungmi Kim
    Department of Biostatistics, University of Alabama, Birmingham, Alabama, USA
    BMC Bioinformatics 7:35. 2006
    ..In some cases this may be manifested as systematic spatial variation on the surface of microarray in which expression measurements within an individual array may vary as a function of geographic position on the array surface...
  7. ncbi request reprint Optimal allocation of replicates for measurement evaluation studies
    Stanislav O Zakharkin
    Department of Biostatistics, University of Alabama at Birmingham, Birmingham, AL 35294 0022, USA
    Genomics Proteomics Bioinformatics 4:196-202. 2006
    ..Therefore, it is recommended to use two technical replicates for each biological replicate if the goal is to evaluate the reproducibility of measurements...
  8. pmc Sources of variation in Affymetrix microarray experiments
    Stanislav O Zakharkin
    University of Alabama, Birmingham, Alabama, USA
    BMC Bioinformatics 6:214. 2005
    ..The objectives of this study were: (1) to estimate relative magnitudes of different sources of variation and (2) to evaluate agreement between biological and technical replicates...
  9. ncbi request reprint Microarray analysis
    Grier P Page
    Department of Biostatistics, University of Alabama at Birmingham, Hoover, AL, USA
    Methods Mol Biol 404:409-30. 2007
    ..These steps include a clearly stated biological question, experimental design, careful experimental conduct, complete statistical analysis, validation/verification of results, and dissemination of the data...
  10. ncbi request reprint Microarray data analysis: from disarray to consolidation and consensus
    David B Allison
    Section on Statistical Genetics, Department of Biostatistics, Ryals Public Health Building, 1665 University Avenue, University of Alabama at Birmingham, Alabama 35294 0022, USA
    Nat Rev Genet 7:55-65. 2006
    ..Many are special cases of more general models, and points of consensus are emerging about the general approaches that warrant use and elaboration...
  11. pmc CressExpress: a tool for large-scale mining of expression data from Arabidopsis
    Vinodh Srinivasasainagendra
    Section on Statistical Genetics, Department of Biostatistics, University of Alabama, Birmingham, Alabama 35294, USA
    Plant Physiol 147:1004-16. 2008
    ..The tool is available at http://www.cressexpress.org...
  12. pmc Human breast fibroblasts inhibit growth of the MCF10AT xenograft model of proliferative breast disease
    Andrea Sadlonova
    Department of Pathology, The University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
    Am J Pathol 170:1064-76. 2007
    ..These findings imply that NAFs can inhibit the growth of normal and hyperplastic epi-thelium but are less able to regulate the more transformed epithelial cells that arise during carcino-genesis...
  13. pmc Identification of molecular distinctions between normal breast-associated fibroblasts and breast cancer-associated fibroblasts
    Andrea Sadlonova
    Department of Pathology, Wallace Tumor Institute, University of Alabama at Birmingham, Room 420, Birmingham, AL 35294, USA
    Cancer Microenviron 2:9-21. 2009
    ..Furthermore, these early passage fibroblast cultures can be representative of gene expression in stromal fibroblasts in vivo...
  14. ncbi request reprint Applications of Bayesian statistical methods in microarray data analysis
    Dongyan Yang
    Section on Statistical Genetics, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    Am J Pharmacogenomics 4:53-62. 2004
    ..Bayesian methods will undoubtedly become more common in the future because of their great utility in microarray analysis...
  15. pmc Transcriptional coordination of the metabolic network in Arabidopsis
    Hairong Wei
    Department of Biostatistics, University of Alabama, Birmingham, Alabama 35294, USA
    Plant Physiol 142:762-74. 2006
    ..These methods and results will aid in the prioritization of candidates for genetic analysis of metabolism in plants and contribute to the improvement of functional annotation of the Arabidopsis genome...
  16. doi request reprint Single nucleotide polymorphisms affect both cis- and trans-eQTLs
    Lang Chen
    Department of Biostatistics, Section on Statistical Genetics, School of Public Health, University of Alabama at Birmingham, AL 35209, USA
    Genomics 93:501-8. 2009
    ..These results indicate that SNPs do affect both probe set summaries and eQTLs (both cis and trans), thus SNP-containing probes should be filtered out to improve the performance of eQTL mapping...
  17. ncbi request reprint The effect of insulin on expression of genes and biochemical pathways in human skeletal muscle
    Xuxia Wu
    Department of Nutrition Sciences, University of Alabama at Birmingham, 1675 University Boulevard, Birmingham, AL 35294 3360, USA
    Endocrine 31:5-17. 2007
    ..The role of NGFI-B (NR4A1) as a new potential mediator of insulin action highlights the need for greater understanding of nuclear transcription factors in insulin action...
  18. pmc HDBStat!: a platform-independent software suite for statistical analysis of high dimensional biology data
    Prinal Trivedi
    Department of Biostatistics, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    BMC Bioinformatics 6:86. 2005
    ..HDBStat! provides statisticians and biologists a flexible and easy-to-use interface to analyze complex microarray data using a variety of methods for data preprocessing, quality control analysis and hypothesis testing...
  19. doi request reprint The association between the rs2234693 and rs9340799 estrogen receptor alpha gene polymorphisms and risk factors for cardiovascular disease: a review
    Krista Casazza
    Department of Nutrition, University of Alabama at Birmingham, AL, USA
    Biol Res Nurs 12:84-97. 2010
    ....
  20. ncbi request reprint Proteomics and mass spectrometry in nutrition research
    Helen Kim
    Department of Pharmacology and Toxicology, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
    Nutrition 20:155-65. 2004
  21. ncbi request reprint Differential gene expression modulated by the cytoplasmic domain of Fc gamma RIa (CD64) alpha-chain
    Hongwei Qin
    Department of Medicine, University of Alabama at Birmingham, 1900 University Boulevard, Birmingham, AL 35294 0006, USA
    J Immunol 173:6211-9. 2004
    ....
  22. pmc Hedgehog signaling and response to cyclopamine differ in epithelial and stromal cells in benign breast and breast cancer
    Shibani Mukherjee
    Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama, USA
    Cancer Biol Ther 5:674-83. 2006
    ..Determination as to whether the increase in GLI1 and SHH expression in breast cancer indicates a significant increase in hedgehog signaling will require further evaluation...
  23. doi request reprint 2D difference gel electrophoresis of prepubertal and pubertal rat mammary gland proteomes
    Helen Kim
    Departments of Pharmacology and Toxicology, the UAB Center for Nutrient Gene Interaction, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
    J Proteome Res 7:4638-50. 2008
    ..This is a first report of mammary gland proteome differences at these important breast cancer-relevant time-points...
  24. ncbi request reprint Employment of microarray analysis to characterize biologic differences associated with tropism-modified adenoviral vectors: utilization of non-native cellular entry pathways
    Andrea L Volk
    Division of Human Gene Therapy and The Gene Therapy Center, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
    Cancer Gene Ther 12:162-74. 2005
    ..This analysis represents a unique application of microarray to study vector-related issues. Furthermore, these studies demonstrate the utility of microarray for characterizing the biologic sequelae of host-vector interaction...
  25. pmc Cross-Chip Probe Matching Tool: A Web-Based Tool for Linking Microarray Probes within and across Plant Species
    Ruchi Ghanekar
    Department of Electrical and Computer Engineering, UAB School of Engineering, University of Alabama at Birmingham, 1530 Third Avenue South, Birmingham, AL 35294 4461, USA
    Int J Plant Genomics 2008:451327. 2008
    ....
  26. pmc Correlation of microRNA levels during hypoxia with predicted target mRNAs through genome-wide microarray analysis
    Jennifer S Guimbellot
    Gregory Fleming James Cystic Fibrosis Research Center, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    BMC Med Genomics 2:15. 2009
    ..The methods described here for comparative analysis of cellular miRNA and mRNA will be useful for understanding genome wide regulatory responsiveness and refining miRNA predictive algorithms...
  27. pmc Bioinformatic tools for inferring functional information from plant microarray data: tools for the first steps
    Grier P Page
    Department of Biostatistics, University of Alabama at Birmingham, 1665 University Blvd Ste 327, Birmingham, AL 35294 0022, USA
    Int J Plant Genomics 2008:147563. 2008
    ....
  28. ncbi request reprint Novel tumor necrosis factor alpha-regulated genes in rheumatoid arthritis
    Huang Ge Zhang
    The University of Alabama at Birmingham, and the Birmingham Department of Veterans Affairs Medical Center, Birmingham, AL 35294 0007, USA
    Arthritis Rheum 50:420-31. 2004
    ..To determine novel genes regulated by tumor necrosis factor alpha (TNFalpha) signaling in primary rheumatoid arthritis synovial fibroblasts (RASFs)...
  29. pmc Bioinformatic Tools for Inferring Functional Information from Plant Microarray Data II: Analysis Beyond Single Gene
    Issa Coulibaly
    Department of Biostatistics, University of Alabama at Birmingham, 1665 University Blvd Ste 327, Birmingham, AL 35294 0022, USA
    Int J Plant Genomics 2008:893941. 2008
    ..The overall goal of this review is to provide researchers with tools and information to facilitate the interpretation of microarray data...
  30. pmc COGA phenotypes and linkages on chromosome 2
    Howard W Wiener
    Department of Epidemiology, School of Public Health, University of Alabama at Birmingham, Birmingham, AL, USA
    BMC Genet 6:S125. 2005
    ..A region on chromosome 2 at 250 cM was found to be linked to both of these derived phenotypes. Further examination of the SNPs in this region identified several haplotypes strongly associated with these derived phenotypes...
  31. ncbi request reprint S-adenosylmethionine prevents chronic alcohol-induced mitochondrial dysfunction in the rat liver
    Shannon M Bailey
    Department of Environmental Health Sciences, School of Public Health, University of Alabama, Birmingham, AL 35294, USA
    Am J Physiol Gastrointest Liver Physiol 291:G857-67. 2006
    ..These findings reveal new molecular targets through which SAM may work to alleviate one critical component of alcohol-induced liver injury: mitochondria dysfunction...
  32. pmc alpha- and gamma-Tocopherol prevent age-related transcriptional alterations in the heart and brain of mice
    Sang Kyu Park
    Department of Genetics and Medical Genetics, University of Wisconsin, Madison, WI 53706, USA
    J Nutr 138:1010-8. 2008
    ..These results demonstrate that middle age-onset dietary supplementation with alphaT and gammaT can partially prevent age-associated transcriptional changes and that these effects are tissue and tocopherol specific...
  33. ncbi request reprint Adipose tissue energy metabolism: altered gene expression profile of mice subjected to long-term caloric restriction
    Yoshikazu Higami
    Wisconsin Primate Research Center, Madison, Wisconsin, USA
    FASEB J 18:415-7. 2004
    ..Our data provide new insights on the metabolic state associated with aging retardation by LCR...
  34. pmc Evaluating statistical methods using plasmode data sets in the age of massive public databases: an illustration using false discovery rates
    Gary L Gadbury
    Department of Statistics, Kansas State University, Manhattan, Kansas, United States of America
    PLoS Genet 4:e1000098. 2008
    ..We use the procedure to compare estimates for the proportion of true null hypotheses, the false discovery rate (FDR), and a local version of FDR obtained from 15 different statistical methods...
  35. pmc Identification of genes required for cellulose synthesis by regression analysis of public microarray data sets
    Staffan Persson
    Department of Plant Biology, Carnegie Institution, Stanford, CA 94305, USA
    Proc Natl Acad Sci U S A 102:8633-8. 2005
    ..Thus, the general approach developed here is useful for identification of elements of multicomponent processes...
  36. pmc DCDC2 is associated with reading disability and modulates neuronal development in the brain
    Haiying Meng
    Department of Pediatrics, Yale Child Health Research Center, Yale University School of Medicine, New Haven, CT 06520, USA
    Proc Natl Acad Sci U S A 102:17053-8. 2005
    ..The statistical and functional studies are complementary and are consistent with the latest clinical imaging data for RD. Thus, we propose that DCDC2 is a candidate gene for RD...
  37. ncbi request reprint Results of a genomewide linkage scan: support for chromosomes 9 and 11 loci increasing risk for cigarette smoking
    Joel Gelernter
    Department of Psychiatry, Yale University School of Medicine, VA Psychiatry 116A2, 950 Campbell Avenue, West Haven, CT 06516, USA
    Am J Med Genet B Neuropsychiatr Genet 128:94-101. 2004
    ..Interestingly, one of our most promising linkage regions, includes a region previously identified as linked to PD...
  38. ncbi request reprint Mitochondrial DNA (mtDNA) haplotypes reveal maternal population genetic affinities of Sea Island Gullah-speaking African Americans
    David C McLean
    Division of Endocrinology, Diabetes, and Medical Genetics, Department of Medicine, Sea Island Families Project and Project Sugar, Medical University of South Carolina, Charleston, SC 20425, USA
    Am J Phys Anthropol 127:427-38. 2005
    ....
  39. ncbi request reprint The Collaborative Cross, a community resource for the genetic analysis of complex traits
    Gary A Churchill
    The Jackson Laboratory, 600 Main Street Bar Harbor, Maine 04609, USA
    Nat Genet 36:1133-7. 2004
    ..The Collaborative Cross will provide a common reference panel specifically designed for the integrative analysis of complex systems and will change the way we approach human health and disease...
  40. pmc Inhaled NO accelerates restoration of liver function in adults following orthotopic liver transplantation
    John D Lang
    Department of Anesthesiology, University of Washington School of Medicine, Seattle, Washington 98108 1597, USA
    J Clin Invest 117:2583-91. 2007
    ..In summary, this study supports the clinical use of iNO as an extrapulmonary therapeutic to improve organ function following transplantation...
  41. ncbi request reprint Empirical Bayes estimation of gene-specific effects in micro-array research
    Jode W Edwards
    United States Department of Agriculture, Agricultural Research Service, Department of Agronomy, Iowa State University, Ames, IA 50014, USA
    Funct Integr Genomics 5:32-9. 2005
    ..e., increase in precision, associated with EB estimators in this analysis. The method described here is available in software that is available at http://www.soph.uab.edu/ssg.asp?id=1087...