Shae B Padrick

Summary

Affiliation: University of Texas Southwestern Medical Center
Country: USA

Publications

  1. pmc Physical mechanisms of signal integration by WASP family proteins
    Shae B Padrick
    Howard Hughes Medical Institute and Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA
    Annu Rev Biochem 79:707-35. 2010
  2. pmc Hierarchical regulation of WASP/WAVE proteins
    Shae B Padrick
    Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
    Mol Cell 32:426-38. 2008

Research Grants

Collaborators

Detail Information

Publications2

  1. pmc Physical mechanisms of signal integration by WASP family proteins
    Shae B Padrick
    Howard Hughes Medical Institute and Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA
    Annu Rev Biochem 79:707-35. 2010
    ..These regulatory principles, derived from studies of WASP and N-WASP, are likely to apply broadly across the family...
  2. pmc Hierarchical regulation of WASP/WAVE proteins
    Shae B Padrick
    Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
    Mol Cell 32:426-38. 2008
    ..Allostery and dimerization act in hierarchical fashion, enabling WASP/WAVE proteins to integrate different classes of inputs to produce a wide range of cellular actin responses...

Research Grants1

  1. Inhibition of Scar by the HEM2/Abi2/Pir121 Complex
    SHAE PADRICK; Fiscal Year: 2005
    ..NMR line broadening experiments will then determine the binding site in terms of specific amino acids and the site will be confirmed by designed point mutants testing the HAP or Arp2/3 binding interfaces. ..