Shae B Padrick
Affiliation: University of Texas Southwestern Medical Center
- Physical mechanisms of signal integration by WASP family proteinsShae B Padrick
Howard Hughes Medical Institute and Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA
Annu Rev Biochem 79:707-35. 2010..These regulatory principles, derived from studies of WASP and N-WASP, are likely to apply broadly across the family...
- Hierarchical regulation of WASP/WAVE proteinsShae B Padrick
Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
Mol Cell 32:426-38. 2008..Allostery and dimerization act in hierarchical fashion, enabling WASP/WAVE proteins to integrate different classes of inputs to produce a wide range of cellular actin responses...
- Inhibition of Scar by the HEM2/Abi2/Pir121 ComplexSHAE PADRICK; Fiscal Year: 2005..NMR line broadening experiments will then determine the binding site in terms of specific amino acids and the site will be confirmed by designed point mutants testing the HAP or Arp2/3 binding interfaces. ..