Research Topics
| Jaume PadillaSummaryAffiliation: University of Missouri Country: USA Publications
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Detail Information
Publications
Adjusting flow-mediated dilation for shear stress stimulus allows demonstration of endothelial dysfunction in a population with moderate cardiovascular riskJaume Padilla
Kinesiology, Indiana University, Bloomington, Ind, USA
J Vasc Res 46:592-600. 2009....
Increased muscle sympathetic nerve activity acutely alters conduit artery shear rate patternsJaume Padilla
Dept of Biomedical Sciences Univ of Missouri, Columbia, 65211, USA
Am J Physiol Heart Circ Physiol 298:H1128-35. 2010..Future studies should examine the complex interaction between MSNA, arterial blood pressure, and other potential modulatory factors of shear rate patterns...- Divergent phenotype of rat thoracic and abdominal perivascular adipose tissuesJaume Padilla
Dept of Biomedical Sciences, E102 Veterinary Medicine, 1600 E Rollins Rd, Univ of Missouri, Columbia, MO 65211
Am J Physiol Regul Integr Comp Physiol 304:R543-52. 2013..Phenotypic differences in PVAT between regions of the aorta may be relevant in light of the evidence in large animals and humans that the abdominal aorta is more vulnerable to atherosclerosis than the thoracic aorta... - Differential changes in vascular mRNA levels between rat iliac and renal arteries produced by cessation of voluntary runningJaume Padilla
Department of Biomedical Sciences, E102 Veterinary Medicine, 1600 East Rollins Road, University of Missouri, Columbia, MO 65211, USA
Exp Physiol 98:337-47. 2013..This heterogeneous influence of short-term physical inactivity could be attributed to the distinct alteration in haemodynamic forces between arteries... - Long-term exercise training does not alter brachial and femoral artery vasomotor function and endothelial phenotype in healthy pigsJaume Padilla
Dept of Biomedical Sciences, W102 Veterinary Medicine, 1600 E Rollins Rd, Univ of Missouri, Columbia, MO 65211, USA
Am J Physiol Heart Circ Physiol 299:H379-85. 2010.... - Impact of aging on conduit artery retrograde and oscillatory shear at rest and during exercise: role of nitric oxideJaume Padilla
Department of Biomedical Sciences, University of Missouri, Columbia, MO 65211, USA
Hypertension 57:484-9. 2011.... - Impact of exercise training on endothelial transcriptional profiles in healthy swine: a genome-wide microarray analysisJaume Padilla
Dept of Biomedical Sciences, E102 Veterinary Medicine, 1600 E Rollins Rd, Univ of Missouri, Columbia, MO 65211, USA
Am J Physiol Heart Circ Physiol 301:H555-64. 2011.... - Brachial artery vasodilatation during prolonged lower limb exercise: role of shear rateJaume Padilla
Department of Biomedical Sciences, E102 Veterinary Medicine, 1600 East Rollins Road, University of Missouri, Columbia, MO 65211, USA
Exp Physiol 96:1019-27. 2011..These results are consistent with the hypothesis that shear stress plays a key role in signalling brachial artery vasodilatation during dynamic leg exercise... - Normalization of flow-mediated dilation to shear stress area under the curve eliminates the impact of variable hyperemic stimulusJaume Padilla
Kinesiology, Indiana University, Bloomington, IN, USA
Cardiovasc Ultrasound 6:44. 2008..The present study was designed to further examine the efficacy of FMD normalization to shear stress in reducing measurement variability... - The flow-mediated dilation response to acute exercise in overweight active and inactive menRyan A Harris
Clinical Exercise Physiology Laboratory, Department of Kinesiology, School of Health, Physical Education and Recreation, Indiana University, Bloomington, IN, USA
Obesity (Silver Spring) 16:578-84. 2008..The aim of this study was to investigate the interaction of IL-6 and TNF-alpha on endothelial function in response to acute exercise in overweight men exhibiting different physical activity profiles... - Increased brachial artery retrograde shear rate at exercise onset is abolished during prolonged cycling: role of thermoregulatory vasodilationGrant H Simmons
E102 Veterinary Medicine Bldg, Univ of Missouri, Columbia, MO 65211, USA
J Appl Physiol 110:389-97. 2011..9 ± 12.5 s(-1)). We conclude that increased brachial artery retrograde SR at the onset of leg cycling subsequently returns toward baseline values due in part to thermoregulatory cutaneous vasodilation during prolonged exercise... - Relationship between brachial and femoral artery endothelial vasomotor function/phenotype in pigsJaume Padilla
Department of Biomedical Sciences, University of Missouri, Columbia, MO 65211, USA
Exp Biol Med (Maywood) 235:1287-91. 2010.... 
Reproducibility of the flow-mediated dilation response to acute exercise in overweight menRyan A Harris
Clinical Exercise Physiology Laboratory, School of Health, Physical Education and Recreation, Department of Kinesiology, Indiana University, Bloomington, IN 47404, USA
Ultrasound Med Biol 33:1579-85. 2007..The findings of the present study support the use of FMD as an outcome variable in response to acute exercise...- The effect of acute exercise on endothelial function following a high-fat mealJaume Padilla
Department of Kinesiology, Clinical Exercise Physiology Laboratory, Indiana University, Bloomington, IN 47405, USA
Eur J Appl Physiol 98:256-62. 2006.... - Variability of flow-mediated dilation measurements with repetitive reactive hyperemiaRyan A Harris
Clinical Exercise Physiology Laboratory, Indiana University, Bloomington, Indiana 47404, USA
Vasc Med 11:1-6. 2006..In addition, this study found no time trends for FMD measurements during the 2-h morning period to allow for pre/post intervention FMD measurements... - Spontaneous bursts of muscle sympathetic nerve activity decrease leg vascular conductance in resting humansSeth T Fairfax
Department of Biomedical Sciences, University of Missouri, Columbia, MO 65212, USA
Am J Physiol Heart Circ Physiol 304:H759-66. 2013.... - Impact of acute exposure to increased hydrostatic pressure and reduced shear rate on conduit artery endothelial function: a limb-specific responseJaume Padilla
Department of Biomedical Sciences, University of Missouri, Columbia, Missouri, USA
Am J Physiol Heart Circ Physiol 297:H1103-8. 2009..Further efforts are needed to determine if this apparent protection of the leg vasculature against an acute hydrostatic challenge is attributable to posture-induced chronic adaptations... - Characterization of the brachial artery shear stress following walking exerciseJaume Padilla
Clinical Exercise Physiology Laboratory, Department of Kinesiology, Indiana University, Bloomington, IN 47405, USA
Vasc Med 13:105-11. 2008..0001) which was abolished after 2 hours. Thus, we found that brachial artery SS is greatest following high-intensity walking and that the rate of decline in SS is similar across all walking intensities... - The exercise dose affects oxidative stress and brachial artery flow-mediated dilation in trained menBlair D Johnson
Department of Kinesiology, Indiana University, Bloomington, IN 47405, USA
Eur J Appl Physiol 112:33-42. 2012..4 vs. 7.6 ± 2.7%). These data suggest that acute exercise-induced TBARS are exercise intensity-dependent whereas FMD appears to improve following energy expenditure equivalent to 30 min 50% VO(2peak), regardless of intensity or duration... - A comparison between active- and reactive-hyperaemia-induced brachial artery vasodilationJaume Padilla
Clinical Exercise Physiology Laboratory, Department of Kinesiology, Indiana University, Bloomington, IN 47405, USA
Clin Sci (Lond) 110:387-92. 2006..18+/-1.13%) treatment. In conclusion, the measurement of brachial artery vasodilation in response to active hyperaemia did not detect a change in endothelial function following a single perturbation meal, whereas reactive hyperaemia did... - Can the measurement of brachial artery flow-mediated dilation be applied to the acute exercise model?Jaume Padilla
Clinical Exercise Physiology Laboratory, Department of Kinesiology, Indiana University, Bloomington, IN, USA
Cardiovasc Ultrasound 5:45. 2007.... - Disturbed blood flow acutely induces activation and apoptosis of the human vascular endotheliumNathan T Jenkins
Department of Biomedical Sciences, University of Missouri, Columbia, MO, USA
Hypertension 61:615-21. 2013..These data provide the first in vivo experimental evidence of disturbed blood flow-induced endothelial injury in humans... - Heterogeneity of endothelial cell phenotype within and amongst conduit vessels of the swine vasculatureGrant H Simmons
Biomedical Sciences, University of Missouri, Columbia, MO, USA
Exp Physiol 97:1074-82. 2012..Importantly, even straight vessel segments from systemic conduit arteries (e.g. brachial and carotid arteries) exhibited regional phenotypic heterogeneity; a finding not expected on the basis of local haemodynamic forces alone... - Effects of endurance exercise training, metformin, and their combination on adipose tissue leptin and IL-10 secretion in OLETF ratsNathan T Jenkins
Department of 1Biomedical Sciences, University of Missouri, Columbia, MO 65211, USA
J Appl Physiol 113:1873-83. 2012..Overall, this study indicates that exercise training and metformin have additive influences on adipose tissue secretion and plasma concentrations of leptin and IL-10... - Vascular effects of exercise: endothelial adaptations beyond active muscle bedsJaume Padilla
Biomedical Sciences, University of Missouri, Columbia, Missouri, USA
Physiology (Bethesda) 26:132-45. 2011.... - Vascular consequences of a high-fat meal in physically active and inactive adultsBlair D Johnson
Clinical Exercise Physiology Laboratory, Department of Kinesiology, Indiana University, Bloomington, IN 47405, USA
Appl Physiol Nutr Metab 36:368-75. 2011..9% ± 3.7% vs. 9.3% ± 3.2%). In conclusion, the differential responses following an HFM support the concept that habitual physical activity can attenuate the negative postprandial alterations that affect vascular health... - Functional adaptations in the skeletal muscle microvasculature to endurance and interval sprint training in the type 2 diabetic OLETF ratJeffrey S Martin
Department of Biomedical Sciences, University of Missouri, Columbia, MO, USA
J Appl Physiol 113:1223-32. 2012.... - Potential clinical translation of juvenile rodent inactivity models to study the onset of childhood obesityMichael D Roberts
Department of Biomedical Sciences, College of Veterinary Medicine, University of Missouri, Columbia, 65211, USA
Am J Physiol Regul Integr Comp Physiol 303:R247-58. 2012..The use of the juvenile rodent WL or other inactivity models will continue to provide a powerful clinical translational tool that can be used for primordial prevention of human childhood obesity... - Accumulation of physical activity reduces blood pressure in pre- and hypertensionJaume Padilla
Clinical Exercise Physiology Laboratory, Department of Kinesiology, Indiana University, Bloomington, IN 47405, USA
Med Sci Sports Exerc 37:1264-75. 2005....