Affiliation: University of California
- Infant siblings and the investigation of autism risk factorsCraig J Newschaffer
Department of Epidemiology and Biostatistics, Drexel School of Public Health, 1505 Race Street, Mail Stop 1033, Philadelphia, PA 19102, USA
J Neurodev Disord 4:7. 2012..It then discusses the key features of this approach and provides a description of the design and implementation strategy of one major ASD enriched-risk pregnancy cohort study: the Early Autism Risk Longitudinal Investigation (EARLI)...
- Recurrence risk for autism spectrum disorders: a Baby Siblings Research Consortium studySally Ozonoff
Department of Psychiatry, University of California Davis, Sacramento, California 95817, USA
Pediatrics 128:e488-95. 2011..This study used prospective methods to obtain an updated estimate of sibling recurrence risk for ASD...
- MMPI-2 personality profiles of high-functioning adults with autism spectrum disordersSally Ozonoff
University of California, Davis, USA
Assessment 12:86-95. 2005..Future directions and implications for identifying adults in need of a specialized autism assessment are discussed...
- Parental report of the early development of children with regressive autism: the delays-plus-regression phenotypeSally Ozonoff
University of California Davis, CA 95817, USA
Autism 9:461-86. 2005..This group, tentatively labeled 'delays-plus-regression', deserves further study...
- Onset patterns in autism: correspondence between home video and parent reportSally Ozonoff
MIND Institute, University of California Davis Health System, Sacramento, CA 95817, USA
J Am Acad Child Adolesc Psychiatry 50:796-806.e1. 2011..This study examined the number and shape of trajectories of symptom onset evident in coded home movies of children with autism and examined their correspondence with parent report of onset...
- Performance on Cambridge Neuropsychological Test Automated Battery subtests sensitive to frontal lobe function in people with autistic disorder: evidence from the Collaborative Programs of Excellence in Autism networkSally Ozonoff
Department of Psychiatry, University of Utah School of Medicine, Salt Lake City, Utah, USA
J Autism Dev Disord 34:139-50. 2004....
- How early do parent concerns predict later autism diagnosis?Sally Ozonoff
M I N D Institute, University of California Davis Health System, Sacramento, CA 95817, USA
J Dev Behav Pediatr 30:367-75. 2009..To study the relationship between parent concerns about development in the first year and a half of life and later autism diagnostic outcomes...
- A prospective study of the emergence of early behavioral signs of autismSally Ozonoff
MIND Institute, University of California Davis, Sacramento, California 95817, USA
J Am Acad Child Adolesc Psychiatry 49:256-66.e1-2. 2010..To examine prospectively the emergence of behavioral signs of autism in the first years of life in infants at low and high risk for autism...
- Imitating actions on objects in early-onset and regressive autism: effects and implications of task characteristics on performanceSally J Rogers
University of California Davis, USA
Dev Psychopathol 22:71-85. 2010..There was no evidence that either motor or attentional aspects of the tasks contributed to the poorer imitative performance of the children with autism...
- Imitation from 12 to 24 months in autism and typical development: a longitudinal Rasch analysisGregory S Young
Medical Investigation of Neurodevelopmental Disorders M I N D Institute, Department of Psychiatry and Behavioral Sciences, University of California, Davis, Sacramento, CA 95817, USA
Dev Psychol 47:1565-78. 2011....
- Play and developmental outcomes in infant siblings of children with autismLisa Christensen
Department of Psychology, University of California, Los Angeles, 1237 Franz Hall, Los Angeles, CA 90095 1563, USA
J Autism Dev Disord 40:946-57. 2010..Group differences disappeared with the inclusion of verbal mental age. Play as an early indicator of autism and its relationship to the broader autism phenotype is discussed...
- Behavioral profiles of affected and unaffected siblings of children with autism: contribution of measures of mother-infant interaction and nonverbal communicationAgata Rozga
Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, CA, USA
J Autism Dev Disord 41:287-301. 2011..However, by 12 months, infants in the ASD group exhibited lower rates of joint attention and requesting behaviors. In contrast, NoASD-sibs did not differ from comparison infants on any variables of interest at 6 and 12 months...
- Gaze behavior and affect at 6 months: predicting clinical outcomes and language development in typically developing infants and infants at risk for autismGregory S Young
MIND Institute, Department of Psychiatry and Behavioral Sciences, School of Medicine, University of California, Davis, CA 95817, USA
Dev Sci 12:798-814. 2009..These findings suggest that although gaze behavior at 6 months may not provide early markers for autism as initially conceived, gaze to the mouth in particular may be useful in predicting individual differences in language development...
- Head circumference and height in autism: a study by the Collaborative Program of Excellence in AutismJanet E Lainhart
Department of Psychiatry, The Brain Institute at the University of Utah, Salt Lake City, Utah 84108, USA
Am J Med Genet A 140:2257-74. 2006..The wide distribution of head circumference in autism has major implications for genetic, neuroimaging, and other neurobiological research...
- Deferred and immediate imitation in regressive and early onset autismSally J Rogers
The MIND Institute, University California Davis, Sacramento, CA 95817, USA
J Child Psychol Psychiatry 49:449-57. 2008..Finally, there were no differences between onset subgroups in imitation scores, suggesting that the two share a similar phenotype involving both types of imitation...
- Is maternal influenza or fever during pregnancy associated with autism or developmental delays? Results from the CHARGE (CHildhood Autism Risks from Genetics and Environment) studyOusseny Zerbo
Department of Public Health Sciences, MS1C, University of California Davis, CA 95616, USA
J Autism Dev Disord 43:25-33. 2013..However, the fever-associated ASD risk was attenuated among mothers who reported taking antipyretic medications (OR = 1.30, 95 % CI 0.59, 2.84), but remained elevated for those who did not (OR = 2.55, 95 % CI 1.30, 4.99)...
- Atypical object exploration at 12 months of age is associated with autism in a prospective sampleSally Ozonoff
MIND Institute, University of California Davis Health System, Sacramento, CA 95817, USA
Autism 12:457-72. 2008..These results suggest that repetitive or stereotyped behaviors may be present earlier than initially thought in very young children developing the autism phenotype...
- Formal thought disorder and the autism spectrum: relationship with symptoms, executive control, and anxietyMarjorie Solomon
Department of Psychiatry and Behavioral Sciences, University of California, Davis, 2230 Stockton Blvd, Sacramento, CA, 95817, USA
J Autism Dev Disord 38:1474-84. 2008..When FTD is present in ASDs, it generally is not a co-morbid schizophrenia symptom, but is related to pragmatic language abnormalities found in ASDs. The clinical and neurobiological significance of this work is discussed...
- What do children with autism attend to during imitation tasks?Giacomo Vivanti
The M I N D Institute, University of California, Davis Medical Center, Sacramento, CA 95817, USA
J Exp Child Psychol 101:186-205. 2008....
- Gross motor development, movement abnormalities, and early identification of autismSally Ozonoff
Department of Psychiatry, University of California Davis Health System, M I N D Institute, 2825 50th Street, Sacramento, CA 95817, USA
J Autism Dev Disord 38:644-56. 2008..These findings do not replicate previous investigations suggesting that early motor abnormalities seen on home video can assist in early identification of autism...
- Examining executive functioning in children with autism spectrum disorder, attention deficit hyperactivity disorder and typical developmentBlythe A Corbett
Departments of Psychiatry and Behavioral Sciences, University of California at Davis, Davis, CA, USA
Psychiatry Res 166:210-22. 2009..In addition, the observed deficits in vigilance and inhibitory control suggest that a significant number of children with ASD present with cognitive profiles consistent with ADHD...
- The onset of autism: patterns of symptom emergence in the first years of lifeSally Ozonoff
M I N D Institute, University of California Davis, Sacramento, USA
Autism Res 1:320-8. 2008..We suggest that onset is better thought of as a dimensional process rather than dichotomous categories...
- A prospective study of response to name in infants at risk for autismAparna S Nadig
University of California Davis M I N D Institute, Sacramento, CA 95817, USA
Arch Pediatr Adolesc Med 161:378-83. 2007..To assess the sensitivity and specificity of decreased response to name at age 12 months as a screen for autism spectrum disorders (ASD) and other developmental delays...
- Behavior and sleep problems in children with a family history of autismAmy Jo Schwichtenberg
Department of Psychiatry and Behavioral Sciences, University of California, Davis, CA, USA
Autism Res 6:169-76. 2013..These findings support close monitoring of children with a family history of ASD for both behavioral and sleep issues...
- Maternal metabolic conditions and risk for autism and other neurodevelopmental disordersPaula Krakowiak
Division of Epidemiology, Department of Public Health Sciences, University of California, Davis, California, USA
Pediatrics 129:e1121-8. 2012....
- Intact emotion facilitation for nonsocial stimuli in autism: is amygdala impairment in autism specific for social information?Mikle South
Department of Psychology, University of Utah, Salt Lake City, Utah, USA
J Int Neuropsychol Soc 14:42-54. 2008....
- Social skills interventions for the autism spectrum: essential ingredients and a model curriculumLori Krasny
Department of Psychiatry, University of Utah, 421 Wakava Way, Suite 143, Salt Lake City, UT 84108, USA
Child Adolesc Psychiatr Clin N Am 12:107-22. 2003..Continued research and treatment for social skills is necessary to provide much needed empiric evidence to determine effectiveness of such interventions...
- Visual Fixation Patterns during Reciprocal Social Interaction Distinguish a Subgroup of 6-Month-Old Infants At-Risk for Autism from Comparison InfantsNoah Merin
Neuroscience Graduate Group and School of Medicine, Class 2008, University of California, Davis, CA, USA
J Autism Dev Disord 37:108-21. 2007..Ten out of the 11 infants in this subgroup had an older sibling with autism...
- Regression in autism: prevalence and associated factors in the CHARGE StudyRobin L Hansen
Medical Investigation of Neurodevelopmental Disorders Institute, University of California, Davis, Sacramento 95817, USA
Ambul Pediatr 8:25-31. 2008..The aim of this study was to examine the prevalence of regressive autism and associated demographic, medical, and developmental factors by using 2 different definitions of regression based on the Autism Diagnostic Interview, Revised...
- Annotation: what do we know about sensory dysfunction in autism? A critical review of the empirical evidenceSally J Rogers
M I N D Institute and Department of Psychiatry and Behavioral Sciences, University of California Davis, CA 95817, USA
J Child Psychol Psychiatry 46:1255-68. 2005..There is a widespread belief that sensory symptoms characterize autism and differentiate it from other disorders. This paper examines the empirical evidence for this assumption...
- Decreased transforming growth factor beta1 in autism: a potential link between immune dysregulation and impairment in clinical behavioral outcomesPaul Ashwood
Department of Medical Microbiology and Immunology, University of California at Davis, United States
J Neuroimmunol 204:149-53. 2008..Such immune dysregulation may predispose to the development of possible autoimmune responses and/or adverse neuroimmune interactions during critical windows in development...
- Early brain enlargement and elevated extra-axial fluid in infants who develop autism spectrum disorderMark D Shen
1 The Medical Investigation of Neurodevelopmental Disorders MIND Institute and Department of Psychiatry and Behavioural Sciences, UC Davis School of Medicine, University of California, Davis, Sacramento, CA, USA
Brain 136:2825-35. 2013..These findings raise the potential for the use of structural magnetic resonance imaging to aid in the early detection of children at risk for autism spectrum disorder or other neurodevelopmental disorders. ..
- Maternal periconceptional folic acid intake and risk of autism spectrum disorders and developmental delay in the CHARGE (CHildhood Autism Risks from Genetics and Environment) case-control studyRebecca J Schmidt
Department of Public Health Sciences, University of California Davis School of Medicine, Davis, CA 95616 8638, USA
Am J Clin Nutr 96:80-9. 2012..Periconceptional folate is essential for proper neurodevelopment...
- Evidence-based assessment of autism spectrum disorders in children and adolescentsSally Ozonoff
M I N D Institute, University of California Medical Center, Sacramento 95817, USA
J Clin Child Adolesc Psychol 34:523-40. 2005..g., parent well-being, family functioning, quality of life). We end with a discussion of how well the extant literature meets criteria for evidence-based assessments...
- Myeloid dendritic cells frequencies are increased in children with autism spectrum disorder and associated with amygdala volume and repetitive behaviorsElizabeth Breece
Department of Medical Microbiology and Immunology, University of California, Davis, USA
Brain Behav Immun 31:69-75. 2013..These data further implicate innate immune cells in the complex pathophysiology of ASD...
- Autism, regression, and the broader autism phenotypeJanet E Lainhart
Department of Psychiatry, University of Utah, Salt Lake City, UT 84108 1236, USA
Am J Med Genet 113:231-7. 2002..Environmental events, however, may act in an additive or "second-hit" fashion in individuals with a genetic vulnerability to autism...
- Brief report: pitocin induction in autistic and nonautistic individualsSusan Gale
Department of Psychology, University of Utah, Salt Lake City, Utah, USA
J Autism Dev Disord 33:205-8. 2003..control) or IQ level (average vs. subaverage range), failing to support an association between exogenous exposure to oxytocin and neurodevelopmental abnormalities...
- Brain enlargement is associated with regression in preschool-age boys with autism spectrum disordersChristine Wu Nordahl
Department of Psychiatry and Behavioral Sciences, Medical Investigation of Neurodevelopmental Disorders Institute, UC Davis School of Medicine, University of California, Sacramento, CA 95817, USA
Proc Natl Acad Sci U S A 108:20195-200. 2011..For boys with regressive autism, divergence in brain size occurs well before loss of skills is commonly reported. Thus, rapid head growth may be a risk factor for regressive autism...
- Gene expression changes in children with autismJeffrey P Gregg
Department of Pathology, University of California at Davis Medical Center, Sacramento, CA 95817, USA University of California at Davis, Davis, CA 95616, USA
Genomics 91:22-9. 2008..05). We conclude that the gene expression data support emerging evidence for abnormalities in peripheral blood leukocytes in autism that could represent a genetic and/or environmental predisposition to the disorder...
- Macrocephaly, corpus callosum morphology, and autismSara A Rice
Department of Psychology and Neuroscience, Brigham Young University, Provo, UT 84602, USA
J Child Neurol 20:34-41. 2005..These findings suggest no unique difference in overall regional corpus callosum surface area in autism with macrocephaly...
- Autism and family home movies: a comprehensive reviewRuben Palomo
Universidad Autonoma de Madrid, Facultad de Psicologia, Madrid, Spain
J Dev Behav Pediatr 27:S59-68. 2006..How family home movies can contribute to our understanding of the regression phenomenon is also addressed. Finally, the results are interpreted from both a theoretical and clinical point of view...
- Examining the relationship between executive functions and restricted, repetitive symptoms of Autistic DisorderBrian R Lopez
Center for Development and Disability, University of New Mexico, 2300 Menaul NE, Albuquerque, NM 87107, USA
J Autism Dev Disord 35:445-60. 2005..The implications for the executive function theory and how the theory predicts core symptoms of autism are discussed...
- Superior temporal gyrus, language function, and autismErin D Bigler
Departments of Psychology and Neuroscience, Brigham Young University, Provo, UT 84602, USA
Dev Neuropsychol 31:217-38. 2007..Taken together, these findings suggest a possible failure in left hemisphere lateralization of language function involving the STG in autism...
- The relationship between executive functioning, central coherence, and repetitive behaviors in the high-functioning autism spectrumMikle South
University of Utah, USA
Autism 11:437-51. 2007..Further research on repetitive behaviors in autism may benefit from a focus on narrow behavioral and cognitive constructs rather than general categories...
- Repetitive behavior profiles in Asperger syndrome and high-functioning autismMikle South
Department of Psychology, University of Utah and Utah Autism Research Project, USA
J Autism Dev Disord 35:145-58. 2005..The importance of expanding research in the repetitive behavior domain is highlighted as part of the necessary integration of behavioral and neurobiological approaches to understanding the etiology of autism...
- Temporal lobe, autism, and macrocephalyErin D Bigler
Department of Psychology and Neuroscience, Brigham Young University, Provo, UT, USA
AJNR Am J Neuroradiol 24:2066-76. 2003..The rationale for the reading disorder group was to have control subjects with potential temporal lobe anomalies, but who were not autistic...
- Utility of the Gilliam Autism Rating Scale in research and clinical populationsMikle South
Department of Psychology, University of Utah, USA
J Autism Dev Disord 32:593-9. 2002..It is recommended that clinicians and researchers using or considering using the GARS for autism diagnosis or ratings of autism severity recognize the need for further research regarding its use...
- Quantitative temporal lobe differences: autism distinguished from controls using classification and regression tree analysisE Shannon Neeley
Department of Statistics, Brigham Young University, Provo, UT 84602, USA
Brain Dev 29:389-99. 2007..Results are discussed in terms of pathological connectivity within the temporal lobe as it relates to autism...
- Infants at Risk of Autism: A Longitudinal StudySally Ozonoff; Fiscal Year: 2010..In study 2, the sample of infant siblings recruited in the prior award period will be followed as they begin school (age 6) to examine the stability of autism diagnoses and identify later-appearing developmental problems. ..
- Infants at Risk of Autism: A Longitudinal StudySally Ozonoff; Fiscal Year: 2007..abstract_text> ..
- Infants at Risk of Autism: A Longitudinal StudySally Ozonoff; Fiscal Year: 2009..The aim of the revision study is to identify changes in brain structure and connectivity in infancy that may be present before the clinical diagnosis of autism is made and indicate increased risk for development of the disorder. ..
- Infants at Risk of Autism: A Longitudinal StudySally Ozonoff; Fiscal Year: 2011..In study 2, the sample of infant siblings recruited in the prior award period will be followed as they begin school (age 6) to examine the stability of autism diagnoses and identify later-appearing developmental problems. ..