Research Topics
| John A OzolekSummaryAffiliation: University of Pittsburgh Country: USA Publications
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Detail Information
Publications
Nasal chondromesenchymal hamartoma in older children and adults: series and immunohistochemical analysisJohn A Ozolek
Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA
Arch Pathol Lab Med 129:1444-50. 2005..Their pathogenesis is unknown, but they may be derived from embryologic rests. To our knowledge, only 1 case in an older child has been reported, and no cases have been reported in adults...- Gliosarcoma with epithelial differentiation: immunohistochemical and molecular characterization. A case report and review of the literatureJohn A Ozolek
Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
Mod Pathol 17:739-45. 2004..This heterogeneity reflects the potential for a range of phenotypic expression in malignant gliomas that needs to be recognized. We suggest microdissection genotyping as a molecular technique to better characterize these tumors... 
Selective pathologies of the head and neck in children: a developmental perspectiveJohn A Ozolek
Department of Pathology, Children s Hospital of Pittsburgh, University of Pittsburgh Medical Center, Pittsburgh, PA 15201, USA
Adv Anat Pathol 16:332-58. 2009....- Human embryonic stem cells (HSF-6) show greater proliferation and apoptoses when grown on glioblastoma cells than mouse embryonic fibroblasts at day 19 in culture: comparison of proliferation, survival, and neural differentiation on two different feeder cJohn A Ozolek
Department of Pathology, University of Pittsburgh, Pittsburgh, PA 15213, USA
Stem Cells Dev 16:403-12. 2007..We speculate differences in proliferation, apoptosis, and neural differentiation may be due to differential elaboration of specific cytokines by MEFs and U87... - Basal/myoepithelial cells in chronic sinusitis, respiratory epithelial adenomatoid hamartoma, inverted papilloma, and intestinal-type and nonintestinal-type sinonasal adenocarcinoma: an immunohistochemical studyJohn A Ozolek
Department of Pathology, Children s Hospital of Pittsburgh, 3705 Fifth Ave, Pittsburgh, PA 15213, USA
Arch Pathol Lab Med 131:530-7. 2007..One feature of malignant glandular lesions is loss of the basal/myoepithelial layer. The immunophenotype of the basal/myoepithelial layer has not been fully examined in benign glandular lesions of the sinonasal tract... - Tumor suppressor gene alterations in respiratory epithelial adenomatoid hamartoma (REAH): comparison to sinonasal adenocarcinoma and inflamed sinonasal mucosaJohn A Ozolek
Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
Am J Surg Pathol 30:1576-80. 2006..Appreciable allelic loss within REAH suggests the possibility that REAH may be a benign neoplasm rather than a hamartoma... - Adenovirus infection within stromal cells in a pediatric small bowel allograftJohn A Ozolek
Department of Pathology, Children s Hospital of Pittsburgh, Pittsburgh, PA, USA
Pediatr Dev Pathol 9:321-7. 2006..This finding should alert pathologists examining small bowel transplant biopsies, particularly those biopsies with extensive ulceration, to include careful surveillance of the lamina propria... - Temporal soft tissue glioneuronal heterotopia in a child with a seizure disorder: case report and review of the literatureJohn A Ozolek
Department of Pathology, Children s Hospital of Pittsburgh, 3705 Fifth Avenue, Pittsburgh, PA 15213, USA
Pediatr Dev Pathol 8:673-9. 2005..We speculate that, in certain circumstances, aberrantly localized CNS tissue may be related to abnormal CNS development... - Inflammatory fibroid polyps of the gastrointestinal tract: clinical, pathologic, and molecular characteristicsJohn A Ozolek
Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
Appl Immunohistochem Mol Morphol 12:59-66. 2004..On biopsy alone, the differential diagnosis may include sarcoma and other malignancies. The absence of mutational change may help to exclude malignant lesions... - In vitro neural differentiation of human embryonic stem cells using a low-density mouse embryonic fibroblast feeder protocolJohn A Ozolek
Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
Methods Mol Biol 584:71-95. 2010..In this chapter, we provide the methods for culturing pluripotent hESCs and MEFs, differentiating hESCs using reduced density MEFs, and phenotypic analyses of this culture system... 
An optimal transportation approach for nuclear structure-based pathologyWei Wang
Center for Bioimage Informatics, Biomedical Engineering Department, Carnegie Mellon University, Pittsburgh, PA 15213, USA
IEEE Trans Med Imaging 30:621-31. 2011..Results automatically computed using this technique show potentially biologically relevant differences in nuclear structure in liver and thyroid cancers...- Human amniotic epithelial cells are reprogrammed more efficiently by induced pluripotency than adult fibroblastsCharles A Easley
Division of Developmental and Regenerative Medicine, Departments of Obstetrics, Gynecology, and Reproductive Sciences, University of Pittsburgh, Pittsburgh, PA 15213, USA
Cell Reprogram 14:193-203. 2012.... - Immunophenotypic comparison of salivary gland oncocytoma and metastatic renal cell carcinomaJohn A Ozolek
Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
Laryngoscope 115:1097-100. 2005..CD10 and CK20 were the most useful markers to distinguish metastatic renal cell carcinoma from oncocytomas in the salivary gland, whereas RCC, EMA, CK7, and vimentin are not as useful... - A general system for automatic biomedical image segmentation using intensity neighborhoodsCheng Chen
Department of Biomedical Engineering, Center for Bioimage Informatics, Carnegie Mellon University, Pittsburgh, PA 15213, USA
Int J Biomed Imaging 2011:606857. 2011.... - Congenital choristomas of the oral cavity in childrenRaymond L Chai
Department of OtolaryngologyChildren s Hospital of Pittsburgh of UPMC, University of Pittsburgh School of Medicine, Pittsburgh, Pennyslvania 15224, USA
Laryngoscope 121:2100-6. 2011..To review our institutional experience with oral cavity choristomas in children... - Detection and classification of thyroid follicular lesions based on nuclear structure from histopathology imagesWei Wang
Center for Bioimage Informatics, Department of Biomedical Engineering, Carnegie Mellon University, Pittsburgh, Pennsylvania 15213, USA
Cytometry A 77:485-94. 2010..We also conclude that the distribution of nuclear size and chromatin concentration (how tightly packed it is) seem to be discriminating features between nuclei of follicular adenoma, follicular carcinoma, and normal thyroid...