John A Ozolek

Summary

Affiliation: University of Pittsburgh
Country: USA

Publications

  1. ncbi request reprint Nasal chondromesenchymal hamartoma in older children and adults: series and immunohistochemical analysis
    John A Ozolek
    Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA
    Arch Pathol Lab Med 129:1444-50. 2005
  2. pmc Accurate diagnosis of thyroid follicular lesions from nuclear morphology using supervised learning
    John A Ozolek
    Department of Pathology, Children s Hospital of Pittsburgh, Pittsburgh, PA 15224, USA Electronic address
    Med Image Anal 18:772-80. 2014
  3. doi request reprint Selective pathologies of the head and neck in children: a developmental perspective
    John A Ozolek
    Department of Pathology, Children s Hospital of Pittsburgh, University of Pittsburgh Medical Center, Pittsburgh, PA 15201, USA
    Adv Anat Pathol 16:332-58. 2009
  4. ncbi request reprint Human embryonic stem cells (HSF-6) show greater proliferation and apoptoses when grown on glioblastoma cells than mouse embryonic fibroblasts at day 19 in culture: comparison of proliferation, survival, and neural differentiation on two different feeder c
    John A Ozolek
    Department of Pathology, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Stem Cells Dev 16:403-12. 2007
  5. ncbi request reprint Basal/myoepithelial cells in chronic sinusitis, respiratory epithelial adenomatoid hamartoma, inverted papilloma, and intestinal-type and nonintestinal-type sinonasal adenocarcinoma: an immunohistochemical study
    John A Ozolek
    Department of Pathology, Children s Hospital of Pittsburgh, 3705 Fifth Ave, Pittsburgh, PA 15213, USA
    Arch Pathol Lab Med 131:530-7. 2007
  6. ncbi request reprint Tumor suppressor gene alterations in respiratory epithelial adenomatoid hamartoma (REAH): comparison to sinonasal adenocarcinoma and inflamed sinonasal mucosa
    John A Ozolek
    Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    Am J Surg Pathol 30:1576-80. 2006
  7. ncbi request reprint Adenovirus infection within stromal cells in a pediatric small bowel allograft
    John A Ozolek
    Department of Pathology, Children s Hospital of Pittsburgh, Pittsburgh, PA, USA
    Pediatr Dev Pathol 9:321-7. 2006
  8. ncbi request reprint Gliosarcoma with epithelial differentiation: immunohistochemical and molecular characterization. A case report and review of the literature
    John A Ozolek
    Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    Mod Pathol 17:739-45. 2004
  9. ncbi request reprint Inflammatory fibroid polyps of the gastrointestinal tract: clinical, pathologic, and molecular characteristics
    John A Ozolek
    Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
    Appl Immunohistochem Mol Morphol 12:59-66. 2004
  10. ncbi request reprint Temporal soft tissue glioneuronal heterotopia in a child with a seizure disorder: case report and review of the literature
    John A Ozolek
    Department of Pathology, Children s Hospital of Pittsburgh, 3705 Fifth Avenue, Pittsburgh, PA 15213, USA
    Pediatr Dev Pathol 8:673-9. 2005

Detail Information

Publications19

  1. ncbi request reprint Nasal chondromesenchymal hamartoma in older children and adults: series and immunohistochemical analysis
    John A Ozolek
    Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA
    Arch Pathol Lab Med 129:1444-50. 2005
    ..Their pathogenesis is unknown, but they may be derived from embryologic rests. To our knowledge, only 1 case in an older child has been reported, and no cases have been reported in adults...
  2. pmc Accurate diagnosis of thyroid follicular lesions from nuclear morphology using supervised learning
    John A Ozolek
    Department of Pathology, Children s Hospital of Pittsburgh, Pittsburgh, PA 15224, USA Electronic address
    Med Image Anal 18:772-80. 2014
    ..In addition, these results could potentially provide nuclear morphological correlates of biological behavior and reduce health care costs by decreasing histotechnician and pathologist time and obviating the need for ancillary testing...
  3. doi request reprint Selective pathologies of the head and neck in children: a developmental perspective
    John A Ozolek
    Department of Pathology, Children s Hospital of Pittsburgh, University of Pittsburgh Medical Center, Pittsburgh, PA 15201, USA
    Adv Anat Pathol 16:332-58. 2009
    ....
  4. ncbi request reprint Human embryonic stem cells (HSF-6) show greater proliferation and apoptoses when grown on glioblastoma cells than mouse embryonic fibroblasts at day 19 in culture: comparison of proliferation, survival, and neural differentiation on two different feeder c
    John A Ozolek
    Department of Pathology, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Stem Cells Dev 16:403-12. 2007
    ..We speculate differences in proliferation, apoptosis, and neural differentiation may be due to differential elaboration of specific cytokines by MEFs and U87...
  5. ncbi request reprint Basal/myoepithelial cells in chronic sinusitis, respiratory epithelial adenomatoid hamartoma, inverted papilloma, and intestinal-type and nonintestinal-type sinonasal adenocarcinoma: an immunohistochemical study
    John A Ozolek
    Department of Pathology, Children s Hospital of Pittsburgh, 3705 Fifth Ave, Pittsburgh, PA 15213, USA
    Arch Pathol Lab Med 131:530-7. 2007
    ..One feature of malignant glandular lesions is loss of the basal/myoepithelial layer. The immunophenotype of the basal/myoepithelial layer has not been fully examined in benign glandular lesions of the sinonasal tract...
  6. ncbi request reprint Tumor suppressor gene alterations in respiratory epithelial adenomatoid hamartoma (REAH): comparison to sinonasal adenocarcinoma and inflamed sinonasal mucosa
    John A Ozolek
    Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    Am J Surg Pathol 30:1576-80. 2006
    ..Appreciable allelic loss within REAH suggests the possibility that REAH may be a benign neoplasm rather than a hamartoma...
  7. ncbi request reprint Adenovirus infection within stromal cells in a pediatric small bowel allograft
    John A Ozolek
    Department of Pathology, Children s Hospital of Pittsburgh, Pittsburgh, PA, USA
    Pediatr Dev Pathol 9:321-7. 2006
    ..This finding should alert pathologists examining small bowel transplant biopsies, particularly those biopsies with extensive ulceration, to include careful surveillance of the lamina propria...
  8. ncbi request reprint Gliosarcoma with epithelial differentiation: immunohistochemical and molecular characterization. A case report and review of the literature
    John A Ozolek
    Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    Mod Pathol 17:739-45. 2004
    ..This heterogeneity reflects the potential for a range of phenotypic expression in malignant gliomas that needs to be recognized. We suggest microdissection genotyping as a molecular technique to better characterize these tumors...
  9. ncbi request reprint Inflammatory fibroid polyps of the gastrointestinal tract: clinical, pathologic, and molecular characteristics
    John A Ozolek
    Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
    Appl Immunohistochem Mol Morphol 12:59-66. 2004
    ..On biopsy alone, the differential diagnosis may include sarcoma and other malignancies. The absence of mutational change may help to exclude malignant lesions...
  10. ncbi request reprint Temporal soft tissue glioneuronal heterotopia in a child with a seizure disorder: case report and review of the literature
    John A Ozolek
    Department of Pathology, Children s Hospital of Pittsburgh, 3705 Fifth Avenue, Pittsburgh, PA 15213, USA
    Pediatr Dev Pathol 8:673-9. 2005
    ..We speculate that, in certain circumstances, aberrantly localized CNS tissue may be related to abnormal CNS development...
  11. doi request reprint In vitro neural differentiation of human embryonic stem cells using a low-density mouse embryonic fibroblast feeder protocol
    John A Ozolek
    Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    Methods Mol Biol 584:71-95. 2010
    ..In this chapter, we provide the methods for culturing pluripotent hESCs and MEFs, differentiating hESCs using reduced density MEFs, and phenotypic analyses of this culture system...
  12. pmc An optimal transportation approach for nuclear structure-based pathology
    Wei Wang
    Center for Bioimage Informatics, Biomedical Engineering Department, Carnegie Mellon University, Pittsburgh, PA 15213, USA
    IEEE Trans Med Imaging 30:621-31. 2011
    ..Results automatically computed using this technique show potentially biologically relevant differences in nuclear structure in liver and thyroid cancers...
  13. pmc A flexible and robust approach for segmenting cell nuclei from 2D microscopy images using supervised learning and template matching
    Cheng Chen
    Center for Bioimage Informatics, Department of Biomedical Engineering, Carnegie Mellon University, Pittsburgh, Pennsylvania 15213, USA
    Cytometry A 83:495-507. 2013
    ....
  14. pmc Detection and classification of thyroid follicular lesions based on nuclear structure from histopathology images
    Wei Wang
    Center for Bioimage Informatics, Department of Biomedical Engineering, Carnegie Mellon University, Pittsburgh, Pennsylvania 15213, USA
    Cytometry A 77:485-94. 2010
    ..We also conclude that the distribution of nuclear size and chromatin concentration (how tightly packed it is) seem to be discriminating features between nuclei of follicular adenoma, follicular carcinoma, and normal thyroid...
  15. doi request reprint Human amniotic epithelial cells are reprogrammed more efficiently by induced pluripotency than adult fibroblasts
    Charles A Easley
    Division of Developmental and Regenerative Medicine, Departments of Obstetrics, Gynecology, and Reproductive Sciences, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Cell Reprogram 14:193-203. 2012
    ....
  16. ncbi request reprint Immunophenotypic comparison of salivary gland oncocytoma and metastatic renal cell carcinoma
    John A Ozolek
    Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
    Laryngoscope 115:1097-100. 2005
    ..This study compared immunohistochemical staining characteristics of oncocytomas arising from salivary gland to metastatic renal cell carcinoma using a panel of markers...
  17. pmc A general system for automatic biomedical image segmentation using intensity neighborhoods
    Cheng Chen
    Department of Biomedical Engineering, Center for Bioimage Informatics, Carnegie Mellon University, Pittsburgh, PA 15213, USA
    Int J Biomed Imaging 2011:606857. 2011
    ....
  18. doi request reprint Pathology of central nervous system posttransplant lymphoproliferative disorders: lessons from pediatric autopsies
    Gabriela Gheorghe
    Department of Pathology, Children s Hospital of Wisconsin, Medical College of Wisconsin, 9000 West Wisconsin Avenue, Milwaukee, WI 53226, USA
    Pediatr Dev Pathol 16:67-73. 2013
    ..In the presence of leptomeningeal involvement, the diagnosis could be made by cerebral spinal fluid examination...
  19. doi request reprint Congenital choristomas of the oral cavity in children
    Raymond L Chai
    Department of OtolaryngologyChildren s Hospital of Pittsburgh of UPMC, University of Pittsburgh School of Medicine, Pittsburgh, Pennyslvania 15224, USA
    Laryngoscope 121:2100-6. 2011
    ..To review our institutional experience with oral cavity choristomas in children...