Aydogan Ozcan

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi Ultra wide-field lens-free monitoring of cells on-chip
    Aydogan Ozcan
    Electrical Engineering Department, University of California, Los Angeles, CA, USA
    Lab Chip 8:98-106. 2008
  2. ncbi Lensfree microscopy on a cellphone
    Derek Tseng
    UCLA Electrical Engineering Department, University of California, Los Angeles, CA 90095, USA
    Lab Chip 10:1787-92. 2010
  3. ncbi Portable and cost-effective pixel super-resolution on-chip microscope for telemedicine applications
    Waheb Bishara
    Department of Electrical Engineering, University of California, Los Angeles 90095, USA
    Conf Proc IEEE Eng Med Biol Soc 2011:8207-10. 2011
  4. ncbi Wide-field fluorescent microscopy on a cell-phone
    Hongying Zhu
    Electrical Engineering Department, University of California, Los Angeles, CA 90095, USA
    Conf Proc IEEE Eng Med Biol Soc 2011:6801-4. 2011
  5. ncbi Optofluidic fluorescent imaging cytometry on a cell phone
    Hongying Zhu
    Electrical Engineering Department, University of California, Los Angeles, Los Angeles, California 90095, USA
    Anal Chem 83:6641-7. 2011
  6. ncbi Compact, light-weight and cost-effective microscope based on lensless incoherent holography for telemedicine applications
    Onur Mudanyali
    Electrical Engineering Department, University of California, Los Angeles, CA 90095, USA
    Lab Chip 10:1417-28. 2010
  7. ncbi Imaging without lenses: achievements and remaining challenges of wide-field on-chip microscopy
    Alon Greenbaum
    Electrical Engineering Department, University of California, Los Angeles, Los Angeles, California, USA
    Nat Methods 9:889-95. 2012
  8. ncbi Optofluidic on-chip tomography
    Serhan O Isikman
    Electrical Engineering Department, University of California, Los Angeles, CA 90095, USA
    Conf Proc IEEE Eng Med Biol Soc 2011:8463-6. 2011
  9. ncbi Lensless fluorescent on-chip microscopy using a fiber-optic taper
    Ahmet F Coskun
    Electrical Engineering Department, University of California, Los Angeles, CA 90095, USA
    Conf Proc IEEE Eng Med Biol Soc 2011:5981-4. 2011
  10. ncbi Lensfree on-chip microscopy over a wide field-of-view using pixel super-resolution
    Waheb Bishara
    Electrical Engineering Department, University of California, Los Angeles, CA 90095, USA
    Opt Express 18:11181-91. 2010

Research Grants

  1. Towards Mega-Throughput, Label-free Genomics and Proteomics: Revolutionizing Micr
    Aydogan Ozcan; Fiscal Year: 2009

Collaborators

  • Waheb Bishara
  • Ting wei Su
  • Serhan O Isikman
  • Wei Luo
  • Liang Xue
  • Utkan Demirci
  • SATYA W DANDEKAR
  • Onur Mudanyali
  • Ahmet F Coskun
  • Hongying Zhu
  • Alon Greenbaum
  • Sam Mavandadi
  • Derek Tseng
  • Ikbal Sencan
  • Sungkyu Seo
  • Uzair Sikora
  • Oguzhan Yaglidere
  • Stoyan Dimitrov
  • Anthony Erlinger
  • Frank Yu
  • Steve Feng
  • Cetin Oztoprak
  • Chulwoo Oh
  • Swati Padmanabhan
  • Serap Altay Arpali
  • Gabriel Biener
  • Gulnaz Stybayeva
  • Hsin Hao Chiang
  • Zoltán Göröcs
  • Caglar Arpali
  • William R Prescott
  • Richard Yu
  • Karin Nielsen-Saines
  • Karin Nielsen
  • Isa Navruz
  • Kelvin Lee
  • Alexander Revzin
  • Bahar Khademhosseinieh
  • Monica Macal
  • Jaime Silangcruz
  • Bahar Khademhosseini
  • Erlan Ramanculov
  • Derek K Tseng

Detail Information

Publications45

  1. ncbi Ultra wide-field lens-free monitoring of cells on-chip
    Aydogan Ozcan
    Electrical Engineering Department, University of California, Los Angeles, CA, USA
    Lab Chip 8:98-106. 2008
    ..An important application of this approach could be a miniaturized point-of-care technology to obtain CD4 T lymphocyte counts of HIV infected patients in resource limited settings...
  2. ncbi Lensfree microscopy on a cellphone
    Derek Tseng
    UCLA Electrical Engineering Department, University of California, Los Angeles, CA 90095, USA
    Lab Chip 10:1787-92. 2010
    ..We report the performance of this lensfree cellphone microscope by imaging various sized micro-particles, as well as red blood cells, white blood cells, platelets and a waterborne parasite (Giardia lamblia)...
  3. ncbi Portable and cost-effective pixel super-resolution on-chip microscope for telemedicine applications
    Waheb Bishara
    Department of Electrical Engineering, University of California, Los Angeles 90095, USA
    Conf Proc IEEE Eng Med Biol Soc 2011:8207-10. 2011
    ..Weighing only ~95 grams, we demonstrate the performance of this field-portable microscope by imaging various objects including human malaria parasites in thin blood smears...
  4. ncbi Wide-field fluorescent microscopy on a cell-phone
    Hongying Zhu
    Electrical Engineering Department, University of California, Los Angeles, CA 90095, USA
    Conf Proc IEEE Eng Med Biol Soc 2011:6801-4. 2011
    ..We demonstrate the performance of this cell-phone fluorescent microscope by imaging labeled white-blood cells separated from whole blood samples as well as water-borne pathogenic protozoan parasites such as Giardia Lamblia cysts...
  5. ncbi Optofluidic fluorescent imaging cytometry on a cell phone
    Hongying Zhu
    Electrical Engineering Department, University of California, Los Angeles, Los Angeles, California 90095, USA
    Anal Chem 83:6641-7. 2011
    ..g., toward monitoring of HIV+ patients) or rare cell analysis as well as for screening of water quality in remote and resource-poor settings...
  6. ncbi Compact, light-weight and cost-effective microscope based on lensless incoherent holography for telemedicine applications
    Onur Mudanyali
    Electrical Engineering Department, University of California, Los Angeles, CA 90095, USA
    Lab Chip 10:1417-28. 2010
    ....
  7. ncbi Imaging without lenses: achievements and remaining challenges of wide-field on-chip microscopy
    Alon Greenbaum
    Electrical Engineering Department, University of California, Los Angeles, Los Angeles, California, USA
    Nat Methods 9:889-95. 2012
    ..5 gigapixels. We also discuss the current challenges that these computational on-chip microscopes face, shedding light on their future directions and applications...
  8. ncbi Optofluidic on-chip tomography
    Serhan O Isikman
    Electrical Engineering Department, University of California, Los Angeles, CA 90095, USA
    Conf Proc IEEE Eng Med Biol Soc 2011:8463-6. 2011
    ..These lensfree holograms are then digitally processed to compute pixel super-resolved tomograms of micro-objects to achieve sectional opto-fluidic imaging on a chip...
  9. ncbi Lensless fluorescent on-chip microscopy using a fiber-optic taper
    Ahmet F Coskun
    Electrical Engineering Department, University of California, Los Angeles, CA 90095, USA
    Conf Proc IEEE Eng Med Biol Soc 2011:5981-4. 2011
    ..g., Giardia Muris cysts). Such a compact and wide-field fluorescent microscopy platform could be valuable for cytometry and rare cell imaging applications as well as for micro array research...
  10. ncbi Lensfree on-chip microscopy over a wide field-of-view using pixel super-resolution
    Waheb Bishara
    Electrical Engineering Department, University of California, Los Angeles, CA 90095, USA
    Opt Express 18:11181-91. 2010
    ..We demonstrate the success of this pixel super-resolution approach by imaging patterned transparent substrates, blood smear samples, as well as Caenoharbditis Elegans...
  11. ncbi Holographic opto-fluidic microscopy
    Waheb Bishara
    Electrical Engineering Department, University of California, Los Angeles, CA 90095, USA
    Opt Express 18:27499-510. 2010
    ..elegans, Giardia lamblia, and Mulberry pollen. HOM does not involve complicated fabrication processes or precise alignment, nor does it require a highly uniform flow of objects within microfluidic channels...
  12. ncbi Color and monochrome lensless on-chip imaging of Caenorhabditis elegans over a wide field-of-view
    Serhan O Isikman
    Electrical Engineering Department, University of California, Los Angeles, CA 90095, USA
    Lab Chip 10:1109-12. 2010
    ..This wide field-of-view and compact on-chip imaging modality also permits straightforward integration with microfluidic systems...
  13. ncbi Lensfree computational microscopy tools for cell and tissue imaging at the point-of-care and in low-resource settings
    Serhan O Isikman
    Electrical Engineering Department, University of California, Los Angeles, USA
    Anal Cell Pathol (Amst) 35:229-47. 2012
    ..g., blood smears, Pap tests and tissue samples. In this article, the basics of these lensfree microscopy modalities will be reviewed, and their clinically relevant applications will be discussed...
  14. ncbi Maskless imaging of dense samples using pixel super-resolution based multi-height lensfree on-chip microscopy
    Alon Greenbaum
    Electrical Engineering Department, University of California, Los Angeles, CA 90095, USA
    Opt Express 20:3129-43. 2012
    ..We demonstrate the success of this multi-height in-line holographic approach by imaging dense Papanicolaou smears (i.e., Pap smears) and blood samples...
  15. ncbi Field-portable lensfree tomographic microscope
    Serhan O Isikman
    UCLA Electrical Engineering Department, University of California, Los Angeles, CA 90095, USA
    Lab Chip 11:2222-30. 2011
    ..Achieving a decent three-dimensional spatial resolution, this field-portable on-chip optical tomographic microscope might provide a useful toolset for telemedicine and high-throughput imaging applications in resource-poor settings...
  16. ncbi Multi-angle lensless digital holography for depth resolved imaging on a chip
    Ting wei Su
    Electrical Engineering Department, University of California, Los Angeles, CA 90095, USA
    Opt Express 18:9690-711. 2010
    ....
  17. ncbi Integrated rapid-diagnostic-test reader platform on a cellphone
    Onur Mudanyali
    Electrical Engineering Department, University of California, Los Angeles, CA 90095, USA
    Lab Chip 12:2678-86. 2012
    ....
  18. ncbi Distributed medical image analysis and diagnosis through crowd-sourced games: a malaria case study
    Sam Mavandadi
    Electrical Engineering Department, University of California Los Angeles, Los Angeles, California, United States of America
    PLoS ONE 7:e37245. 2012
    ..Specifically, using non-expert gamers we report diagnosis of malaria infected red blood cells with an accuracy that is within 1.25% of the diagnostics decisions made by a trained medical professional...
  19. ncbi Lensfree super-resolution holographic microscopy using wetting films on a chip
    Onur Mudanyali
    Electrical Engineering Department, University of California, Los Angeles, CA 90095, USA
    Opt Express 19:17378-89. 2011
    ..These results are especially important for the development of highly sensitive field-portable microscopic analysis tools for resource limited settings...
  20. ncbi Holographic pixel super-resolution in portable lensless on-chip microscopy using a fiber-optic array
    Waheb Bishara
    Electrical Engineering Department, University of California, Los Angeles, CA 90095, USA
    Lab Chip 11:1276-9. 2011
    ..Our results constitute the first-time that a lensfree on-chip microscope has successfully imaged malaria parasites...
  21. ncbi Compact and light-weight automated semen analysis platform using lensfree on-chip microscopy
    Ting wei Su
    Electrical Engineering Department, University of California, Los Angeles, California, USA
    Anal Chem 82:8307-12. 2010
    ....
  22. ncbi Multi-angle LUCAS for high-throughput on-chip cytometry
    Ting wei Su
    Electrical Engineering Department, University of California, Los Angeles, CA 90095, USA
    Conf Proc IEEE Eng Med Biol Soc 2008:1854-5. 2008
    ..This platform, termed multi-angle LUCAS, is especially promising for cost-effective point-of-care cell counting applications...
  23. ncbi Lensless wide-field fluorescent imaging on a chip using compressive decoding of sparse objects
    Ahmet F Coskun
    Electrical Engineering Department, University of California, Los Angeles, CA, USA
    Opt Express 18:10510-23. 2010
    ..e., over an imaging field-of-view of >8 cm(2). Such a wide-field lensless fluorescent imaging platform could especially be significant for high-throughput imaging cytometry, rare cell analysis, as well as for micro-array research...
  24. ncbi Detection of waterborne parasites using field-portable and cost-effective lensfree microscopy
    Onur Mudanyali
    Electrical Engineering Department, UCLA, CA 90095, USA
    Lab Chip 10:2419-23. 2010
    ....
  25. ncbi Lensfree optofluidic microscopy and tomography
    Waheb Bishara
    Electrical Engineering Department, University of California, Los Angeles, CA, USA
    Ann Biomed Eng 40:251-62. 2012
    ..Based on lensfree digital holographic imaging, this optofluidic microscopy and tomography concept could be valuable especially for providing a compact, yet powerful toolset for lab-on-a-chip devices...
  26. ncbi Lensfree holographic imaging of antibody microarrays for high-throughput detection of leukocyte numbers and function
    Gulnaz Stybayeva
    Department of Biomedical Engineering, University of California, Davis, CA 95616, USA
    Anal Chem 82:3736-44. 2010
    ....
  27. ncbi Lensfree fluorescent on-chip imaging of transgenic Caenorhabditis elegans over an ultra-wide field-of-view
    Ahmet F Coskun
    Electrical Engineering Department, University of California Los Angeles, Los Angeles, California, United States of America
    PLoS ONE 6:e15955. 2011
    ..This unique combination permits ultra-wide field dual-mode imaging of C. elegans on a chip which could especially provide a useful tool for high-throughput screening applications in biomedical research...
  28. ncbi Combined reflection and transmission microscope for telemedicine applications in field settings
    Gabriel Biener
    UCLA Electrical Engineering Department, University of California, Los Angeles, CA 90095, USA
    Lab Chip 11:2738-43. 2011
    ..Being compact, light-weight and cost-effective, this combined reflection and transmission microscope might especially be useful for telemedicine applications in resource limited settings...
  29. ncbi High-throughput lensfree 3D tracking of human sperms reveals rare statistics of helical trajectories
    Ting wei Su
    Electrical Engineering Department, University of California, Los Angeles, CA 90095, USA
    Proc Natl Acad Sci U S A 109:16018-22. 2012
    ..This high-throughput 3D imaging platform could in general be quite valuable for observing the statistical swimming patterns of various other microorganisms, leading to new insights in their 3D motion and the underlying biophysics...
  30. ncbi Field-portable wide-field microscopy of dense samples using multi-height pixel super-resolution based lensfree imaging
    Alon Greenbaum
    UCLA Electrical Engineering Department, University of California, Los Angeles, CA 90095, USA
    Lab Chip 12:1242-5. 2012
    ..Our results reveal the promising potential of this multi-height lensfree computational microscopy platform for e.g., pathology needs in resource limited settings...
  31. ncbi Crowd-sourced BioGames: managing the big data problem for next-generation lab-on-a-chip platforms
    Sam Mavandadi
    Electrical Engineering Department, University of California, Los Angeles, CA, USA
    Lab Chip 12:4102-6. 2012
    ....
  32. ncbi Partially coherent lensfree tomographic microscopy [Invited]
    Serhan O Isikman
    Electrical Engineering Department, University of California, Los Angeles, California 90095, USA
    Appl Opt 50:H253-64. 2011
    ..Therefore, lensfree optical tomography might be particularly useful for lab-on-a-chip applications as well as for microscopy needs in resource-limited settings...
  33. ncbi Quantum dot enabled detection of Escherichia coli using a cell-phone
    Hongying Zhu
    Electrical Engineering Department, University of California, Los Angeles, 90095, USA
    Analyst 137:2541-4. 2012
    ..coli detection platform for e.g., screening of water and food samples even in resource limited environments. The presented platform can also be applicable to other pathogens of interest through the use of different antibodies...
  34. ncbi High-throughput lens-free blood analysis on a chip
    Sungkyu Seo
    Electrical Engineering Department, University of California, Los Angeles, California 90095, USA
    Anal Chem 82:4621-7. 2010
    ..These results uncover the prospects of lens-free holographic on-chip imaging to provide a useful tool for global health problems, especially by facilitating whole blood analysis in resource-poor environments...
  35. ncbi Lensfree holographic imaging for on-chip cytometry and diagnostics
    Sungkyu Seo
    Electrical Engineering Department, University of California, Los Angeles, CA 90095, USA
    Lab Chip 9:777-87. 2009
    ..This lensless on-chip holography platform will especially be useful for point-of-care cytometry and diagnostics applications involving e.g., infectious diseases such as HIV or malaria...
  36. ncbi Lens-free optical tomographic microscope with a large imaging volume on a chip
    Serhan O Isikman
    Electrical Engineering Department, University of California, Los Angeles, CA, USA
    Proc Natl Acad Sci U S A 108:7296-301. 2011
    ..Probing a large volume with a decent 3D spatial resolution, this lens-free optical tomography platform on a chip could provide a powerful tool for high-throughput imaging applications in, e.g., cell and developmental biology...
  37. ncbi Optical imaging techniques for point-of-care diagnostics
    Hongying Zhu
    Electrical Engineering Department, University of California, Los Angeles, CA 90095, USA
    Lab Chip 13:51-67. 2013
    ..Here, we review the state-of-the-art optical imaging techniques that can have a significant impact on global health by facilitating effective and affordable POC diagnostics...
  38. ncbi A mathematical framework for combining decisions of multiple experts toward accurate and remote diagnosis of malaria using tele-microscopy
    Sam Mavandadi
    Electrical Engineering Department, University of California Los Angeles, Los Angeles, California, United States of America
    PLoS ONE 7:e46192. 2012
    ..g., thin blood smear samples. This framework could be generalized for various other tele-pathology needs, and can be used by trained experts within an efficient tele-medicine platform...
  39. ncbi Giga-pixel lensfree holographic microscopy and tomography using color image sensors
    Serhan O Isikman
    Electrical Engineering Department, University of California Los Angeles, Los Angeles, California, United States of America
    PLoS ONE 7:e45044. 2012
    ..We demonstrate the proof-of-concept of this lensfree optical tomographic microscopy platform on a color CMOS image sensor by creating tomograms of micro-particles as well as a wild-type C. elegans nematode...
  40. ncbi Wide-field lensless fluorescent microscopy using a tapered fiber-optic faceplate on a chip
    Ahmet F Coskun
    Electrical Engineering Department, University of California, Los Angeles, CA 90095, USA
    Analyst 136:3512-8. 2011
    ....
  41. ncbi Cost-effective and compact wide-field fluorescent imaging on a cell-phone
    Hongying Zhu
    UCLA Electrical Engineering Department, Los Angeles, CA 90095, USA
    Lab Chip 11:315-22. 2011
    ....
  42. ncbi Wide field-of-view lens-free fluorescent imaging on a chip
    Ahmet F Coskun
    Electrical Engineering Department, University of California, Los Angeles, CA 90095, USA
    Lab Chip 10:824-7. 2010
    ....
  43. ncbi On-chip differential interference contrast microscopy using lensless digital holography
    Chulwoo Oh
    Electrical Engineering Department, University of California, Los Angeles, CA, USA
    Opt Express 18:4717-26. 2010
    ....
  44. ncbi High-throughput lensfree imaging and characterization of a heterogeneous cell solution on a chip
    Ting wei Su
    Electrical Engineering Department, University of California, P O Box 951594, Los Angeles, California 90095, USA
    Biotechnol Bioeng 102:856-68. 2009
    ....
  45. ncbi High-throughput screening of large volumes of whole blood using structured illumination and fluorescent on-chip imaging
    Serap Altay Arpali
    Electrical Engineering Department, University of California, Los Angeles, CA 90095, USA
    Lab Chip 12:4968-71. 2012
    ....

Research Grants2

  1. Towards Mega-Throughput, Label-free Genomics and Proteomics: Revolutionizing Micr
    Aydogan Ozcan; Fiscal Year: 2009
    ....