M A Oyama

Summary

Affiliation: University of Pennsylvania
Country: USA

Publications

  1. doi The use of NT-proBNP assay in the management of canine patients with heart disease
    Mark A Oyama
    Department of Clinical Studies, University of Pennsylvania, Philadelphia, PA 19104, USA
    Vet Clin North Am Small Anim Pract 40:545-58. 2010
  2. ncbi Using cardiac biomarkers in veterinary practice
    Mark A Oyama
    Section of Cardiology, Department of Clinical Studies Philadelphia, School of Veterinary Medicine, University of Pennsylvania, 3900 Delancey Street, Philadelphia, PA 19104, USA Electronic address
    Vet Clin North Am Small Anim Pract 43:1261-72, vi. 2013
  3. pmc Arrhythmogenic right ventricular cardiomyopathy in Boxer dogs is associated with calstabin2 deficiency
    Mark A Oyama
    University of Pennsylvania, Philadelphia, PA, USA, USA
    J Vet Cardiol 10:1-10. 2008
  4. ncbi Carvedilol in dogs with dilated cardiomyopathy
    Mark A Oyama
    Department of Veterinary Clinical Medicine, College of Veterinary Medicine, University of Illinois, Urbana, IL, USA
    J Vet Intern Med 21:1272-9. 2007
  5. doi Decreased triadin and increased calstabin2 expression in Great Danes with dilated cardiomyopathy
    M A Oyama
    Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
    J Vet Intern Med 23:1014-9. 2009
  6. ncbi Acute conversion of atrial fibrillation in two dogs by intravenous amiodarone administration
    Mark A Oyama
    Department of Veterinary Clinical Medicine, College of Veterinary Medicine, University of Illinois, Urbana, USA
    J Vet Intern Med 20:1224-7. 2006
  7. doi Insights into serotonin signaling mechanisms associated with canine degenerative mitral valve disease
    M A Oyama
    Department of Clinical Studies Philadelphia, School of Veterinary Medicine, University of Pennsylvania, 3900 Delancey St, Philadelphia, PA 19104, USA
    J Vet Intern Med 24:27-36. 2010
  8. doi Assessment of serum N-terminal pro-B-type natriuretic peptide concentration for differentiation of congestive heart failure from primary respiratory tract disease as the cause of respiratory signs in dogs
    Mark A Oyama
    Department of Clinical Studies Philadelphia, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
    J Am Vet Med Assoc 235:1319-25. 2009
  9. doi Calculation of pressure half-time
    Mark A Oyama
    Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, 3900 Delancey Street, PA 19104, USA
    J Vet Cardiol 10:57-60. 2008
  10. doi Use of the loop diuretic torsemide in three dogs with advanced heart failure
    Mark A Oyama
    Department of Clinical Studies Philadelphia, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
    J Vet Cardiol 13:287-92. 2011

Detail Information

Publications46

  1. doi The use of NT-proBNP assay in the management of canine patients with heart disease
    Mark A Oyama
    Department of Clinical Studies, University of Pennsylvania, Philadelphia, PA 19104, USA
    Vet Clin North Am Small Anim Pract 40:545-58. 2010
    ..The incorporation of NT-proBNP assay into successful clinical practice requires an understanding of the science behind the technology, as well as the clinical data available to date...
  2. ncbi Using cardiac biomarkers in veterinary practice
    Mark A Oyama
    Section of Cardiology, Department of Clinical Studies Philadelphia, School of Veterinary Medicine, University of Pennsylvania, 3900 Delancey Street, Philadelphia, PA 19104, USA Electronic address
    Vet Clin North Am Small Anim Pract 43:1261-72, vi. 2013
    ..Usage of cardiac biomarker testing in clinical practice relies on proper patient selection, correct interpretation of test results, and incorporation of biomarker testing into existing diagnostic methods. ..
  3. pmc Arrhythmogenic right ventricular cardiomyopathy in Boxer dogs is associated with calstabin2 deficiency
    Mark A Oyama
    University of Pennsylvania, Philadelphia, PA, USA, USA
    J Vet Cardiol 10:1-10. 2008
    ..To examine the presence and effect of calstabin2-deficiency in Boxer dogs with arrhythmogenic right ventricular cardiomyopathy (ARVC)...
  4. ncbi Carvedilol in dogs with dilated cardiomyopathy
    Mark A Oyama
    Department of Veterinary Clinical Medicine, College of Veterinary Medicine, University of Illinois, Urbana, IL, USA
    J Vet Intern Med 21:1272-9. 2007
    ..Dilated cardiomyopathy (DCM) is characterized by reduced systolic function, heightened sympathetic tone, and high morbidity and mortality. Little is known regarding the safety and efficacy of beta-blocker treatment in dogs with DCM...
  5. doi Decreased triadin and increased calstabin2 expression in Great Danes with dilated cardiomyopathy
    M A Oyama
    Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
    J Vet Intern Med 23:1014-9. 2009
    ..Dilated cardiomyopathy (DCM) is a common cardiac disease of Great Dane dogs, yet very little is known about the underlying molecular abnormalities that contribute to disease...
  6. ncbi Acute conversion of atrial fibrillation in two dogs by intravenous amiodarone administration
    Mark A Oyama
    Department of Veterinary Clinical Medicine, College of Veterinary Medicine, University of Illinois, Urbana, USA
    J Vet Intern Med 20:1224-7. 2006
  7. doi Insights into serotonin signaling mechanisms associated with canine degenerative mitral valve disease
    M A Oyama
    Department of Clinical Studies Philadelphia, School of Veterinary Medicine, University of Pennsylvania, 3900 Delancey St, Philadelphia, PA 19104, USA
    J Vet Intern Med 24:27-36. 2010
    ....
  8. doi Assessment of serum N-terminal pro-B-type natriuretic peptide concentration for differentiation of congestive heart failure from primary respiratory tract disease as the cause of respiratory signs in dogs
    Mark A Oyama
    Department of Clinical Studies Philadelphia, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
    J Am Vet Med Assoc 235:1319-25. 2009
    ....
  9. doi Calculation of pressure half-time
    Mark A Oyama
    Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, 3900 Delancey Street, PA 19104, USA
    J Vet Cardiol 10:57-60. 2008
    ..Thus, PHT increases as the severity of stenosis increases. In this report, we describe the methodology involved in measuring PHT in a dog with mitral valve stenosis before and after balloon valvuloplasty...
  10. doi Use of the loop diuretic torsemide in three dogs with advanced heart failure
    Mark A Oyama
    Department of Clinical Studies Philadelphia, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
    J Vet Cardiol 13:287-92. 2011
    ..This case report details the administration of torsemide in 3 dogs with advanced heart failure and apparent furosemide resistance...
  11. doi Effect of azotemia on serum N-terminal proBNP concentration in dogs with normal cardiac function: a pilot study
    M K Schmidt
    College of Veterinary Medicine, University of Florida, Gainesville, FL 32610, USA
    J Vet Cardiol 11:S81-6. 2009
    ..To evaluate amino-terminal pro-B type natriuretic peptide (NT-proBNP) concentration in dogs with renal dysfunction and normal cardiac structure and function...
  12. doi Effect of NT-pro-BNP assay on accuracy and confidence of general practitioners in diagnosing heart failure or respiratory disease in cats with respiratory signs
    G E Singletary
    Department of Clinical Studies Philadelphia, Matthew J Ryan Veterinary Hospital of University of Pennsylvania, Philadelphia, PA 19104, USA
    J Vet Intern Med 26:542-6. 2012
    ....
  13. doi Serum serotonin concentrations in dogs with degenerative mitral valve disease
    J W Arndt
    Department of Clinical Studies Philadelphia, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
    J Vet Intern Med 23:1208-13. 2009
    ..High circulating 5HT concentration is a potential source of increased signaling, and serum 5HT concentrations have not been previously reported in dogs with DMVD...
  14. doi Clinical utility of serum N-terminal pro-B-type natriuretic peptide concentration for identifying cardiac disease in dogs and assessing disease severity
    Mark A Oyama
    Department of Veterinary Clinical Studies Philadelphia, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
    J Am Vet Med Assoc 232:1496-503. 2008
    ..To determine whether serum N-terminal pro-B-type natriuretic (NT-proBNP) concentration could be used to identify cardiac disease in dogs and to assess disease severity in affected dogs...
  15. doi Prospective evaluation of NT-proBNP assay to detect occult dilated cardiomyopathy and predict survival in Doberman Pinschers
    G E Singletary
    Department of Clinical Studies Philadelphia, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
    J Vet Intern Med 26:1330-6. 2012
    ..Occult (asymptomatic) dilated cardiomyopathy (ODCM) is highly prevalent in Doberman Pinschers...
  16. ncbi Two-dimensional and M-mode echocardiographic predictors of disease severity in dogs with congenital subaortic stenosis
    Mark A Oyama
    Department of Medicine and Epidemiology, College of Veterinary Medicine, University of California, Davis 95616, USA
    J Am Anim Hosp Assoc 38:209-15. 2002
    ..The ratio of these two areas demonstrated a strong inverse relationship (P=0.001; r2=0.778) with disease severity. This ratio provides a method of estimating severity of disease by two-dimensional echocardiography...
  17. ncbi Practices and outcome of artificial cardiac pacing in 154 dogs
    M A Oyama
    Department of Cardiology, College of Veterinary Medicine, University of Illinois, Urbana 61801, USA
    J Vet Intern Med 15:229-39. 2001
    ..001). Sixty percent of dogs with preexisting CHF died within 1 year of implantation, whereas 25% of dogs without heart failure died during the same period. Owners rated their satisfaction with the procedure as high in 80% of the dogs...
  18. doi Gerbode type defect and third degree atrioventricular block in association with bacterial endocarditis in a dog
    Gordon D Peddle
    Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
    J Vet Cardiol 10:133-9. 2008
    ..The authors hypothesize that the Gerbode type defect in this case was acquired secondary to invasion and destruction of the membranous interventricular septum due to bacterial endocarditis...
  19. doi Agitated saline contrast echocardiography to diagnose a congenital heart defect in a dog
    Jason W Arndt
    Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104, United States
    J Vet Cardiol 10:129-32. 2008
    ..Agitated saline contrast echocardiography is easily performed and well-tolerated and in this report, we demonstrate the utility of this method to diagnose a rare congenital defect in a dog...
  20. ncbi Cardiac troponin-I concentration in dogs with cardiac disease
    Mark A Oyama
    Department of Veterinary Clinical Medicine, College of Veterinary Medicine, University of Illinois, Urbana, IL 61802, USA
    J Vet Intern Med 18:831-9. 2004
    ..20 ng/mL (112 days versus 357 days; P = .006). Plasma cTnI is high in dogs with cardiac disease, correlates with heart size and survival, and can be used as a blood-based biomarker of cardiac disease...
  21. ncbi Plasma endothelin-1 immunoreactivity in normal dogs and dogs with acquired heart disease
    Robert Prosek
    Department of Veterinary Clinical Medicine, College of Veterinary Medicine, University of Illinois, Urbana, IL, USA
    J Vet Intern Med 18:840-4. 2004
    ..0001, r2 = .30) or body surface area (BSA) (P = .0071, r2 = .10), and left ventricular internal dimension at end-systole indexed to aortic diameter (P = .0003, r- = .17) or BSA (P = .0008, r2 = .15)...
  22. ncbi Prospective screening for occult cardiomyopathy in dogs by measurement of plasma atrial natriuretic peptide, B-type natriuretic peptide, and cardiac troponin-I concentrations
    Mark A Oyama
    Department of Veterinary Clinical Medicine, College of Veterinary Medicine, University of Illinois, Urbana, IL 61802, USA
    Am J Vet Res 68:42-7. 2007
    ..To evaluate the use of measuring plasma concentrations of atrial natriuretic peptide (ANP), B-type natriuretic peptide (BNP), and cardiac troponin-I (cTnI) to detect dogs with occult dilated cardiomyopathy (DCM)...
  23. doi Neurohormonal activation in canine degenerative mitral valve disease: implications on pathophysiology and treatment
    M A Oyama
    Department of Clinical Studies Philadelphia, School of Veterinary Medicine, University of Pennsylvania, 3900 Delancey St, Philadelphia, PA 19107, USA
    J Small Anim Pract 50:3-11. 2009
    ..Thus, knowledge of neurohormonal mechanisms can lead to a better understanding of how to treat DMVD...
  24. doi Perceptions of quality of life and priorities of owners of cats with heart disease
    C A Reynolds
    Department of Clinical Studies Philadelphia, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
    J Vet Intern Med 24:1421-6. 2010
    ....
  25. ncbi Runaway pacemaker in a dog
    Robert Prosek
    University of Illinois, Veterinary Teaching Hospital, Urbana, IL, USA
    J Vet Intern Med 18:242-4. 2004
  26. ncbi Third degree atrioventricular block and sudden death secondary to acute myocarditis in a dog
    Whitney M Church
    Department of Veterinary Clinical Medicine, Matthew J Ryan Veterinary Hospital, Philadelphia, PA 19104, USA
    J Vet Cardiol 9:53-7. 2007
    ..This report suggests that measurement of cardiac troponin I may be an indicated test before pacemaker implantation in dogs with third degree AV block...
  27. ncbi Comparison of canine cardiac troponin I concentrations as determined by 3 analyzers
    Darcy B Adin
    Department of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, USA
    J Vet Intern Med 20:1136-42. 2006
    ..Recent interest in cardiac biomarkers has led to the validation of several commercial analyzers for cardiac troponin I (cTnI) evaluation in dogs; however, these analyzers have not been standardized...
  28. ncbi What is your diagnosis? Pericardial effusion with a clot in the pericardial space likely caused by left atrial rupture secondary to mitral regurgitation
    Robert Prosek
    Department of Veterinary Clinical Medicine, College of Veterinary Medicine, University of Illinois, Urbana, IL 61802, USA
    J Am Vet Med Assoc 222:441-2. 2003
  29. doi Weekly variability of plasma and serum NT-proBNP measurements in normal dogs
    Heidi B Kellihan
    University of Wisconsin, School of Veterinary Medicine, Department of Medicine, 2015 Linden Dr Madison, WI 53711, USA
    J Vet Cardiol 11:S93-7. 2009
    ..To determine the weekly variability of serum and plasma N-terminal pro-B-type natriuretic peptide (NT-proBNP) concentrations in healthy dogs...
  30. ncbi Evaluation of canine congenital heart disease using an echocardiographic algorithm
    M A Oyama
    Department of Veterinary Clinical Medicine, College of Veterinary Medicine, University of Illinois at Urbana-Champaign, Urbana 61802, USA
    J Am Anim Hosp Assoc 37:519-35. 2001
    ..This algorithm is supported by a number of still figures within the article as well as real-time echocardiographic images available for viewing at AAHA's website, www.aahanet.org...
  31. ncbi Implantation of a single-lead atrioventricular synchronous (VDD) pacemaker in a dog with naturally occurring 3rd-degree atrioventricular block
    Barret J Bulmer
    University of Illinois, College of Veterinary Medicine, Urbana, 61802, USA
    J Vet Intern Med 16:197-200. 2002
  32. ncbi Echocardiographic estimation of mean left atrial pressure in a canine model of acute mitral valve insufficiency
    Mark A Oyama
    Department of Veterinary Clinical Medicine, College of Veterinary Medicine, University of Illinois, Urbana, IL 61801, USA
    J Vet Intern Med 18:667-72. 2004
    ..1 or <6.0 indicated a 95% probability that MLAP was >20 mm Hg or <20 mm Hg, respectively. Echocardiography can be used to predict MLAP in isoflurane-anesthetized dogs with experimentally induced acute mitral valve insufficiency...
  33. ncbi Measurements of plasma endothelin immunoreactivity in healthy cats and cats with cardiomyopathy
    Robert Prosek
    Department of Veterinary Clinical Medicine, College of Veterinary Medicine, University of Illinois, Urbana, IL, USA
    J Vet Intern Med 18:826-30. 2004
    ..Plasma immunoreactivity of ET-1 was significantly higher in cats with myocardial disease without CHF/STE versus normal cats (P < .05) and in cats with myocardial disease with CHF/STE versus normal cats (P < .001)...
  34. ncbi Correlation of mitochondrial protein expression in complexes I to V with natural and induced forms of canine idiopathic dilated cardiomyopathy
    Rosana Lopes
    Department of Veterinary Clinical Medicine, College of Veterinary Medicine, University of Illinois at Urbana Champaign, Urbana, IL 61802, USA
    Am J Vet Res 67:971-7. 2006
    ..To identify qualitative and quantitative differences in cardiac mitochondrial protein expression in complexes I to V between healthy dogs and dogs with natural or induced dilated cardiomyopathy (DCM)...
  35. ncbi Characterization of canine mitochondrial protein expression in natural and induced forms of idiopathic dilated cardiomyopathy
    Rosana Lopes
    Department of Veterinary Clinical Medicine, College of Veterinary Medicine, University of Illinois at Urbana Champaign, Urbana, IL 61802, USA
    Am J Vet Res 67:963-70. 2006
    ..To map canine mitochondrial proteins and identify qualitative and quantitative differences in heart mitochondrial protein expression between healthy dogs and dogs with naturally occurring and induced dilated cardiomyopathy (DCM)...
  36. ncbi Advances in echocardiography
    Mark A Oyama
    Department of Veterinary Clinical Medicine, College of Veterinary Medicine, University of Illinois, 1008 West Hazelwood Drive, Urbana, IL 61802, USA
    Vet Clin North Am Small Anim Pract 34:1083-104, v. 2004
    ..Within these sections, emerging technologies that expand the capabilities of the echocardiographic examination are introduced...
  37. doi Perceptions and priorities of owners of dogs with heart disease regarding quality versus quantity of life for their pets
    Mark A Oyama
    Department of Clinical Studies Philadelphia, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
    J Am Vet Med Assoc 233:104-8. 2008
    ..To describe the relative importance of pets' quality versus quantity of life among owners of dogs with heart disease...
  38. ncbi Genomic expression patterns of cardiac tissues from dogs with dilated cardiomyopathy
    Mark A Oyama
    Department of Veterinary Clinical Medicine, College of Veterinary Medicine, University of Illinois, Urbana, IL 61802, USA
    Am J Vet Res 66:1140-55. 2005
    ..To evaluate global genome expression patterns of left ventricular tissues from dogs with dilated cardiomyopathy (DCM)...
  39. ncbi ECG of the month. Complete AV block, and lack of capture (pacing) of the ventricles by the single-lead atrial-sensing VDD system
    Robert Prosek
    Department of Veterinary Clinical Medicine, College of Veterinary Medicine, University of Illinois, Urbana, IL 61802, USA
    J Am Vet Med Assoc 225:845-6. 2004
  40. ncbi Genomic expression patterns of mitral valve tissues from dogs with degenerative mitral valve disease
    Mark A Oyama
    Department of Veterinary Clinical Medicine, College of Veterinary Medicine, University of Illinois, Urbana, 61802, USA
    Am J Vet Res 67:1307-18. 2006
    ..To evaluate global genome expression patterns of mitral valve tissues from dogs with degenerative mitral valve disease (DMVD)...
  41. doi Canine heterophilic antibodies as a source of false-positive B-type natriuretic peptide sandwich ELISA results
    Philip F Solter
    College of Veterinary Medicine, University of Illinois, 2001 S Lincoln Drive, Urbana, IL 61902, USA
    Vet Clin Pathol 37:86-95. 2008
    ..They are considered rarely in veterinary species and have not been characterized but could become important as newer, highly sensitive sandwich immunoassay technologies are developed...
  42. ncbi Assessment of cardiac chamber size using anatomic M-mode
    Mark A Oyama
    Department of Veterinary Clinical Medicine, University of Illinois, Urbana, IL 61802, USA
    Vet Radiol Ultrasound 46:331-6. 2005
    ..AMM. In healthy dogs, cardiac AMM measurements are associated with greater accuracy and less variability than CMM. AMM has the potential to improve quantification of cardiac dimensions...
  43. ncbi Physiologic VDD versus nonphysiologic VVI pacing in canine 3rd-degree atrioventricular block
    Barret J Bulmer
    Department of Veterinary Clinical Medicine, College of Veterinary Medicine, University of Illinois, Urbana, USA
    J Vet Intern Med 20:257-71. 2006
    ..VDD pacing improved hemodynamics and neurohormonal profiles over asynchronous pacing although the long-term clinical benefits of these changes remain to be determined...
  44. pmc Fenfluramine disrupts the mitral valve interstitial cell response to serotonin
    Jeanne M Connolly
    Division of Cardiology, The Children s Hospital of Philadelphia, 3615 Civic Center Boulevard, Philadelphia, PA 19104 4318, USA
    Am J Pathol 175:988-97. 2009
    ..This imbalance may explain in part the pathophysiology of Fen-related mitral valve disease...
  45. ncbi Distinguishing cardiac and noncardiac dyspnea in 48 dogs using plasma atrial natriuretic factor, B-type natriuretic factor, endothelin, and cardiac troponin-I
    Robert Prosek
    Veterinary Specialists Incorporated Animal Heart Centers, 91 NE 6th Street, Homestead, FL 33030, USA
    J Vet Intern Med 21:238-42. 2007
    ..It is challenging to differentiate congestive heart failure (CHF) from noncardiac cause of dyspnea...